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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 636 of 725

Negative / Null Result ReportMedicine

"Did I buy that just now?" - Investigating factors influencing the accuracy of food choice self-reports in a simulated online grocery store.

Manzke L, O'Sullivan K, Tiefenbeck V · 2025 · Appetite

Food choices profoundly impact population health and the environment. Related research often relies on self-reported data, which is prone to biases, compromising the accuracy and validity of conclusions about consumer behavior. There are…

View details →DOI: 10.1016/j.appet.2025.108032
Negative / Null Result ReportMedicine

Delivering health care without degrading health: Factors associated with hospital commitment to environmental sustainability.

Ranucci R · 2025 · Health care management review

Background In delivering health care, hospitals contribute to climate change, which adversely impacts human health. Given this paradox, there are mounting efforts to encourage environmental sustainability in hospitals. Purpose With growing…

View details →DOI: 10.1097/hmr.0000000000000439
Negative / Null Result ReportMedicine

Faster bladder filling in rats reduces detrusor overactivity but worsens (i.e., decreases) bladder compliance.

He W, Slavik N, Braun J et al. · 2024 · American journal of physiology. Renal physiology

The impact of bladder filling rate on cystometric outcomes remains unclear. Clinically, faster bladder filling is believed to increase the likelihood of observing detrusor overactivity (DO) in those with bladder dysfunction, although…

View details →DOI: 10.1152/ajprenal.00209.2024
Negative / Null Result ReportMedicine

Evaluating NLP Approaches to Extract Drug Indications.

Sarkar IN · 2026 · AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Reliable drug-indication knowledge is essential for clinical decision support and pharmacovigilance, yet manual curation is labor-intensive and difficult to scale. This study evaluated nine natural language processing approaches to extract…

Failed Experiment Report

A field experiment assessing the roles of drought, herbivory, and local climate on cyanogenesis cline formation and local adaptation in Trifolium repens

Albano LJ, Patterson CM, Kidder EJ et al. · 2025 · Preprint

Projecting how a population will adapt to environmental changes requires a mechanistic understanding of the specific biotic and abiotic factors that impose selection on that population. In white clover ( Trifolium repens ), clines in an…

View details →DOI: 10.1101/2025.03.07.642096
Failed Experiment ReportMedicine

Contribution of individual legs to overall attachment in the adult ladybird Harmonia axyridis depends on the relative leg orientation to an external force

Saitta V, Rebora M, Piersanti S et al. · 2025 · Entomologia Experimentalis et Applicata.

This study investigates the attachment ability of harlequin ladybird, Harmonia axyridis (Pallas) (Coleoptera: Coccinellidae), focusing on the synergic action of opposite legs, the anisotropy of adhesive organs and sexual dimorphism.…

View details →DOI: 10.1111/eea.13535
Failed Experiment ReportMedicine

The effect of increased strength on ball release speed and front foot contact-phase technique in elite male cricket fast bowlers.

Felton PJ, Shine KJ, Yeadon MR et al. · 2025 · Journal of sports sciences

Research on strength in cricket fast bowling has focused on ball release speed over technique. This study investigates how increased strength affects performance and front foot contact-phase technique during fast bowling. A planar,…

View details →DOI: 10.1080/02640414.2025.2480921
Negative / Null Result ReportMedicine

Lighting Up MS2: Exploring Fluence Rates for Virus Inactivation

Pousty D, Betzalel Y, Mamane H · 2025 · AWWA Water Science

This study examined the impact of UV‐LED fluence rate (incident irradiance) and wavelengths on the inactivation of MS2 bacteriophage, determined by log reduction value (LRV). Three levels of fluence rates, each differing by an order of…

Negative / Null Result ReportOpen accessMedicine

Reciprocal cross-feeding between bacteria can limit the emergence of metabolic dependencies.

Chuang Y-C, Behringer MG, Patton GE et al. · 2026 · Applied and environmental microbiology

Cross-feeding is prevalent in microbial communities. Through time, cross-feeding is thought to enrich for loss-of-function mutations, thereby creating or reinforcing dependencies between community members. However, few studies have…

View details →DOI: 10.1128/aem.00363-26
Negative / Null Result ReportMedicine

Referral to chronic pain management and physiotherapy services in adults with severe mental illness: A matched cohort study.

Ma R, Romano E, Perera G et al. · 2025 · General hospital psychiatry

Introduction Chronic pain (CP) is common among people with severe mental illness (SMI). It remains unclear whether patients with comorbid CP and SMI receive equivalent pain management referrals compared to those with CP alone. This…

View details →DOI: 10.1016/j.genhosppsych.2025.05.013
Failed Experiment ReportMedicine

Geometric, cell cycle and maternal-to-zygotic transition-associated YAP dynamics during preimplantation embryo development.

Chalifoux M, Avdeeva M, Posfai E · 2025 · Developmental biology

During the first cell fate decision in mammalian embryos, the inner cell mass cells, which will give rise to the embryo proper and other extraembryonic tissues, segregate from the trophectoderm cells, the precursors of the placenta. Cell…

View details →DOI: 10.1016/j.ydbio.2025.05.006
Failed Experiment ReportMedicine

Population Genomics of <i>Macrophomina</i> spp. Reveals Cryptic Host Specialization and Evidence for Meiotic Recombination.

Pennerman KK, Goldman P, Dilla-Ermita CJ et al. · 2025 · Molecular plant-microbe interactions : MPMI

Knowledge of the factors structuring populations of pathogenic fungi is fundamental to disease management efforts and basic biology. However, this crucial information is missing for many important pathogens, including broad-host-range and…

View details →DOI: 10.1094/mpmi-03-25-0032-r
Negative / Null Result ReportMedicine

The effect of an Iyengar yoga-based exercise programme versus a seated yoga relaxation programme on falls in people aged 60 years and older (SAGE): a pragmatic, two-arm, parallel randomised controlled trial.

Oliveira JS, Sherrington C, Lord SR et al. · 2025 · The lancet. Healthy longevity

Background Exercises targeting balance and strength are proven to prevent falls. Yoga is growing in popularity and can improve balance and mobility in older adults, but its effects on falls have not been rigorously tested. In this study,…

View details →DOI: 10.1016/j.lanhl.2025.100749
Negative / Null Result ReportOpen accessMedicine

Performance of next-generation AI chatbots in gynecological knowledge assessment: a comparative pilot study of ChatGPT-5, Gemini-3, DeepSeek-V3.2, and Claude-4.5-Opus.

Huan O, Wang Z · 2026 · Archives of gynecology and obstetrics

Purpose As artificial intelligence (AI) models evolve into their next generations, their application in specialized medical fields requires rigorous validation. While large language models (LLMs) have shown promise in general medicine,…

View details →DOI: 10.1007/s00404-026-08358-7
Negative / Null Result ReportMedicine

Preferences for Gender Stereotypicality in Artificial Intelligence: Existence, Comparison to Human Biases, and Implications for Choice.

Spielmann J, Stern C · 2026 · Personality & social psychology bulletin

Do people prefer that artificial intelligence (AI) aligns with gender stereotypes when requesting help to answer a question? We found that people preferred gender stereotypicality (over counterstereotypicality and androgyny) in voice-based…

View details →DOI: 10.1177/01461672241307276
Failed Experiment ReportMedicine

Optimizing Genome Editing in Mollusks (<i>Crassostrea gigas</i>) <i>in Vitro</i> Validation of sgRNA and Identifying Key Factors Influencing Efficiency.

Li Q, Yu H, Du S et al. · 2025 · The CRISPR journal

CRISPR-Cas9 genome editing holds tremendous potential for accelerating genetic improvements in aquaculture. The success of the CRISPR-Cas9 system relies on the specificity and efficiency of engineered single-guide RNAs (sgRNAs). In this…

View details →DOI: 10.1089/crispr.2024.0086