Negative / Null Result ReportMedicine
Moosavi, Khorakian, Sedaghati et al. · 2026 · BMC oral health
Severe caries in mixed dentition frequently affects mandibular first permanent molars, often necessitating full-coverage restorations. Stainless steel crowns (SSCs) and porcelain-fused-to-metal (PFM) crowns are among the most commonly used…
View details →DOI: 10.1186/s12903-026-08831-4 Negative / Null Result ReportMedicine
Yue, Kong, Huang et al. · 2026 · BMC cancer
The optimal timing for thermal ablation (TA) in patients with colorectal liver metastases (CRLM) eligible for local curative therapy remains undefined. This study aimed to evaluate the impact of time to ablation (TTA) on long-term survival…
View details →DOI: 10.1186/s12885-026-16333-3 Negative / Null Result ReportMedicine
Roberts, Waddell, Atkins et al. · 2026 · The New Zealand medical journal
Our aim was to determine the 30- and 90-day all-cause mortality of healthcare-associated Staphylococcus aureus bacteraemia (HA-SAB) and determine mortality risk factors. We collected HA-SAB events from 1 July 2022 to 30 June 2024. Patient…
View details →DOI: 10.26635/6965.7321 Negative / Null Result ReportMedicine
McFarland, Sihra, Walker et al. · 2026 · Journal of racial and ethnic health disparities
To evaluate Black birthing people's knowledge of American Academy of Pediatrics (AAP) infant safe sleep recommendations over time in the context of a substantial, county-wide, tailored public health initiative against infant mortality.…
View details →DOI: 10.1007/s40615-026-02942-y Negative / Null Result ReportMedicine
Benyamini, Khan, Elmenawi et al. · 2026 · Hip international : the journal of clinical and experimental research on hip pathology and therapy
Glucagon-like peptide-1 (GLP-1) receptor agonists are increasingly utilised for metabolic optimisation in surgical patients. Their effect on postoperative patient-reported outcomes (PROMs) and satisfaction following primary total hip…
View details →DOI: 10.1177/11207000261450078 Negative / Null Result ReportMedicine
Rajvanshi, Kumar, Goyal et al. · 2026 · Pediatric pulmonology
Flexible fibreoptic bronchoscopy (FFB) is widely used in pediatric pulmonology, though hypoxemia remains a primary concern during the procedure. High-flow nasal cannula (HFNC) has shown potential in reducing hypoxemia in adults undergoing…
View details →DOI: 10.1002/ppul.71683 Negative / Null Result ReportMedicine
Dhakar, Ghori, Parihar et al. · 2026 · The Gulf journal of oncology
Oral cavity cancers often require radiotherapy (RT), leading to toxicities such as xerostomia, skin reactions, and mucositis. This study aims to compare these toxicities between three-dimensional conformal radiotherapy (3D-CRT) and…
Negative / Null Result ReportMedicine
Granfeldt, Kirkegaard, Vallentin et al. · 2026 · JAMA
Patients with in-hospital cardiac arrest have poor outcomes. Sodium bicarbonate is commonly administered during cardiac arrest, but the effects on clinical outcomes are unknown. To determine whether administration of sodium bicarbonate…
View details →DOI: 10.1001/jama.2026.10628 Negative / Null Result ReportMedicine
Itoh, Iseda, Yoshizumi et al. · 2026 · Cancer medicine
We examine the impact of interferon (IFN)-based and IFN-free treatment on the prognosis of hepatocellular carcinoma (HCC) after hepatitis C virus (HCV) sustained virological response (SVR). Clinical information was collected on 311 cases…
View details →DOI: 10.1002/cam4.71963 Negative / Null Result ReportMedicine
Naoumova, Nawaia, Krekmanova · 2026 · European journal of orthodontics
Extraction of mandibular primary second molars in patients with congenitally missing second premolars may influence oral health-related quality of life (OHRQoL), yet this has not been previously investigated. To assess the impact of…
View details →DOI: 10.1093/ejo/cjag048 Negative / Null Result ReportMedicine
Tsujimoto, Yamashiro, Suzuki et al. · 2026 · International journal of endocrinology
Adult growth hormone deficiency (AGHD) is often diagnosed after surgery for nonfunctioning pituitary neuroendocrine tumor (NF-PitNET). While a growth hormone stimulation test (GHST) is required to establish its diagnosis, it is associated…
View details →DOI: 10.1155/ije/8842344 Negative / Null Result ReportMedicine
Fukue, Suetomi, Matsuura et al. · 2026 · Circulation reports
As part of work-style reform for physicians, task shifting to non-physician healthcare professionals has been promoted in Japan. We previously reported task shifting results for percutaneous coronary interventions (PCI), but the status in…
View details →DOI: 10.1253/circrep.cr-25-0329 Negative / Null Result ReportMedicine
Tomita, Kakuta, Kainuma et al. · 2026 · Circulation reports
Robotic mitral valve repair (MVr) offers superior visualization and dexterity, potentially overcoming challenges in severe thoracic deformity such as pectus excavatum. This study compared surgical outcomes after MVr in patients with and…
View details →DOI: 10.1253/circrep.cr-26-0003 Negative / Null Result ReportMedicine
Liu, Xiang, Li et al. · 2026 · Frontiers in psychology
To better serve the best interests of minors, there is a growing consensus on the need for differentiated correction approaches for juvenile offenders based on their classifications. To implement these tailored interventions, it is…
View details →DOI: 10.3389/fpsyg.2026.1704471 Negative / Null Result ReportMedicine
Ranabothu, Smith, Perkins et al. · 2026 · Pediatric transplantation
Pediatric kidney transplant recipients typically receive low-KDPI deceased donor kidneys but often experience higher HLA mismatches. The relationship between KDPI and HLA mismatch and their combined effect on graft and patient outcomes in…
View details →DOI: 10.1111/petr.70351 Negative / Null Result ReportMedicine
Kamagaté, Jusot, Mory et al. · 2026 · Therapeutic advances in drug safety
In Côte d'Ivoire, pharmacovigilance is not a routine activity in most healthcare facilities and many healthcare professionals have limited knowledge of pharmacovigilance methods. This study aimed to evaluate the quality of adverse…
View details →DOI: 10.1177/20420986261446480 Negative / Null Result ReportMedicine
Saeed, Jalal · 2026 · Pulmonary medicine
The COVID-19 pandemic, caused by SARS-CoV-2, has led to significant global mortality and morbidity. Angiotensin-converting Enzyme 2 (ACE2) has been identified as the primary receptor for viral entry into host cells and is believed to play…
View details →DOI: 10.1155/pm/1013605 Negative / Null Result ReportMedicine
Mohammed, Naser, Abozaid · 2026 · Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
Composite resin placement technique may influence marginal integrity, polymerization stress distribution, and long-term clinical performance of posterior restorations. This randomized controlled clinical trial evaluated the 24-month…
View details →DOI: 10.1111/jerd.70202 Negative / Null Result ReportMedicine
Niu, Bao, Zhao · 2026 · Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
This study aimed to systematically evaluate the efficacy and safety of different doses of domperidone (DOM) combined with esomeprazole (ESM) in the treatment of reflux esophagitis, providing a basis for precise clinical medication. This…
View details →DOI: 10.1093/dote/doag053 Negative / Null Result ReportMedicine
Shi, Yuan, Gao et al. · 2026 · Journal of neuroengineering and rehabilitation
Transcranial magnetic stimulation (TMS), as a non-invasive neurostimulation technique, modulates neural activity by applying electromagnetic fields to specific areas of the brain. It is clinically used for several approved indications,…
View details →DOI: 10.1186/s12984-026-02045-z Negative / Null Result ReportMedicine
Yakıt Yeşilyurt, Birinci Olgun, Dağ et al. · 2026 · BMC women's health
Breathing exercises may modulate dysmenorrhea by enhancing relaxation and eliciting analgesic effects. This study investigated the effects of Pelvic Floor Muscle Training (PFMT) with or without Dynamic Neuromuscular Stabilization…
View details →DOI: 10.1186/s12905-026-04578-w Negative / Null Result ReportMedicine
Chen, Song, Zang et al. · 2026 · BMC anesthesiology
Right lateral thoracotomy cardiac surgery induces postoperative atelectasis due to cardiopulmonary bypass (CPB), patient positioning, and mechanical ventilation. Fixed positive end-expiratory pressure (PEEP) may fail to meet pediatric…
View details →DOI: 10.1186/s12871-026-03947-0 Negative / Null Result ReportMedicine
Yıldız, Çalış, Dokuz et al. · 2026 · Psychiatry research
This study examined differences in choroidal structural parameters, including the choroidal vascularity index, among patients with schizophrenia, bipolar disorder, and healthy controls. This cross-sectional study included 40 patients with…
View details →DOI: 10.1016/j.psychres.2026.117268 Negative / Null Result ReportMedicine
Chen, Yi, Cao et al. · 2026 · Neurology
The efficacy of endovascular treatment for acute large vessel occlusion strokes has been demonstrated, but whether it can improve functional outcomes in patients with acute ischemic stroke (AIS) who only present with severe large vessel…
View details →DOI: 10.1212/wnl.0000000000218157 Negative / Null Result ReportMedicine
Bejarano, Hull, Young et al. · 2026 · PloS one
We exploit state-level policy changes for physical therapy direct access to estimate the effect of enacting direct access physical therapy policy on per-capita opioid pill volume (PCPV) and opioid-related deaths (ORD) compared to states…
View details →DOI: 10.1371/journal.pone.0333292 Negative / Null Result ReportMedicine
Wonglhow, Wetwittayakhlang, Sunpaweravong et al. · 2026 · Cancer management and research
Ampullary adenocarcinoma is a rare malignancy with limited evidence on the efficacy of systemic chemotherapy for advanced disease. This study aimed to evaluate the treatment outcomes of gemcitabine- and fluoropyrimidine-based regimens and…
View details →DOI: 10.2147/cmar.s608153 Negative / Null Result ReportMedicine
Acar, Özdemir, Yalinay Dikmen · 2026 · Frontiers in neurology
Emerging evidence suggests that circadian rhythms may influence migraine pathophysiology through interactions between sleep-wake regulation and pain modulation pathways. This study aimed to investigate the association between chronotype…
View details →DOI: 10.3389/fneur.2026.1812863 Negative / Null Result ReportMedicine
Yanaoka, Tyler, Hasegawa · 2026 · Frontiers in physiology
This study investigated the effect of body mass (BM) on the efficacy of mixed-method cooling (ice slurry ingestion + cooling vest) applied between exercise bouts. Sixteen males completed two experimental trials in the heat (35°C, 50%…
View details →DOI: 10.3389/fphys.2026.1817856 Negative / Null Result ReportMedicine
Hogmark, Westermark, Envall et al. · 2026 · Acta obstetricia et gynecologica Scandinavica
Intrauterine devices (IUDs) effectively prevent unwanted pregnancies. Little is known about long-term outcomes of women choosing an IUD after second-trimester medical abortion. We performed a 12-month follow-up of a multicenter randomized…
View details →DOI: 10.1111/aogs.70259 Negative / Null Result ReportMedicine
Zhou, Bian, Yang et al. · 2026 · Interdisciplinary cardiovascular and thoracic surgery
The micropapillary pattern is a high-risk factor for postoperative recurrence in lung adenocarcinoma (LUAD), but the role of adjuvant chemotherapy (ACT) in stage IA LUAD with micropapillary pattern (LUADmp) after resection remains unclear.…
View details →DOI: 10.1093/icvts/ivag165