A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21742 results · page 632 of 725
Keskin HO, Ozkara E, Erzurumluoglu E et al. · 2026 · Biomedicines
Background: Meningiomas exhibit considerable biological heterogeneity that is not fully captured by histopathological grading. Tissue-based molecular markers may provide complementary insight into tumor biology within routine diagnostic…
Ghobashy MK, AbdelFatah MA, Youssef ME et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
Purpose Posterior vertebral column resection (PVCR) for severe post-traumatic thoracic angular kyphosis is effective but carries high morbidity. This study compares unilateral PVCR (UPVCR) with traditional bilateral PVCR (BPVCR),…
Kurihara Y, Tsuchiya A, Dumas G et al. · 2026 · Preprint
Summary Joint agency, the shared feeling of “we are doing this together”, has been linked to inter-brain synchrony, but its causal role in shaping this experience remains unclear. We applied dual transcranial alternating current…
Mausz J, Donnelly EA, Batt AM et al. · 2026 · Preprint
Objectives: Paramedics are at elevated risk for adverse mental health outcomes due to occupational exposures including trauma, workplace violence, and chronic operational stress. Community Paramedicine (CP) represents an evolving model of…
Nakauchi C, Masunaga N, Eguchi Y et al. · 2026 · BMC cancer
Background Immunohistochemistry (IHC) is widely used to determine estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2) status, which are crucial for predicting breast cancer recurrence and guiding adjuvant therapy…
Gözener Canbülbül S, Canbülbül B, Özcan Şİ et al. · 2026 · Journal of pediatric rehabilitation medicine
PurposeThis pilot study aimed to compare the effects of face-to-face and telerehabilitation approaches on thoracic hyperkyphosis, back extensor muscle strength, and discomfort in children.MethodsA randomized clinical trial was conducted in…
Potluri AS, Yadav AS, Weintraub MT et al. · 2026 · The Journal of arthroplasty
Introduction This multicenter randomized controlled trial (RCT) sought to determine if dual-mobility bearings (DM) reduce dislocations in patients at high-risk for instability undergoing primary total hip arthroplasty (THA) compared to…
Nakamae A, Nekomoto A, Nakata K et al. · 2026 · The journal of knee surgery
Abstract This study aimed to identify factors associated with greater quantitative pivot shift in anterior cruciate ligament (ACL)-injured knees by quantitatively assessing the pivot shift under anesthesia using a navigation system prior…
Cakir M, Buyuk C, Kan B · 2026 · The International journal of oral & maxillofacial implants
Purpose Achieving optimal primary stability is critical for dental implant success, particularly in low-density bone regions such as the posterior maxilla. Conventional high-speed drilling with irrigation may remove vital bone fragments…
Kawaguchi M, Hoshina M, Sugahara S et al. · 2026 · Cureus
Objective This pilot study investigated the dosimetric impact of artificial intelligence (AI)-generated seminal vesicle (SV) autocontouring (AC) compared with manual contouring (MC) in high-risk prostate cancer volumetric-modulated arc…
Erken AA, Dincer ST · 2026 · Asia-Pacific journal of clinical oncology
Aim Total neoadjuvant therapy has been adopted to improve systemic disease control in locally advanced rectal cancer, yet long-term real-world outcomes, particularly in non-Western populations, remain incompletely defined. We compared…
Benedikt M, Herrmann M, Aziz F et al. · 2026 · Journal of clinical medicine
Background : Sodium glucose-linked transport 2 inhibitors (SGLT2-Is) are well known to exert beneficial effects in chronic heart failure (CHF) independent of left ventricular ejection fraction (LVEF). As inflammation plays a key role in…
Whiteside SPH, Gloe LM, Biggs BK · 2026 · Journal of clinical psychology
Objectives Cognitive behavioral therapy (CBT) is the most researched treatment for childhood anxiety disorders (CADs). Improving outcomes and efficiency of CBT will require identifying and optimizing the most efficacious therapeutic…
Erdoğan F, Cengiz T, Şimşek ŞA et al. · 2026 · Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
Background Pediatric femoral neck fractures are rare but carry a high risk of complications such as avascular necrosis (AVN), premature physeal closure, and coxa vara. Although stable internal fixation is essential, the optimal number of…
Pandey K, Choubey B, Gupta N et al. · 2026 · Journal of neonatal-perinatal medicine
BackgroundRespiratory distress is a frequent complication in preterm infants, often requiring respiratory support. Respiratory distress syndrome (RDS), caused by surfactant deficiency in the immature lung, is the predominant etiology in…
Makiev EA, Kozhevnikova TN, Pronin AV et al. · 2026 · Voprosy virusologii
Objective To evaluate how influenza infection affects the hypolipidemic effect of a novel combined drug - Prenophytol based on polyisoprenoids (sodium polyprenyl phosphate and beta-sitosterol) in mice with experimental dyslipidemia.…
Mohamed FB, Middleton DM, Manmatharayan A et al. · 2026 · Spinal cord
Study design (Phantom & Human) OBJECTIVE: The purpose of this study was to optimize imaging sequences to suppress artifacts induced by metallic hardware, using phantoms implanted with spinal hardware and participants with spinal cord…
Khawaja SA, Hanna L, Singh A et al. · 2026 · EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Background Stroke remains a significant concern in patients undergoing Transcatheter Aortic Valve Implantation (TAVI). Despite advances in TAVI technology and techniques, rates have remained unchanged, with trials of Cerebral embolic…
Wang J, Ma Y · 2026 · BMC ophthalmology
Background The efficacy and safety profile of the active-fluidics system (AFS) in diabetic cataract patients remains inadequately characterized. This study specifically evaluated AFS versus gravity-fluidics system (GFS) in type 2 diabetes…
Reis AM, Barros AS, Poças PS et al. · 2026 · The Journal of sports medicine and physical fitness
Background Jumper's knee, also known as patellar tendinopathy, is a common overuse injury among athletes involved in sports that require repetitive jumping and high-impact activities, such as volleyball. Understanding the risk factors…
Savaş EM, Bozkurt HH, Kemer NI et al. · 2026 · Leukemia research
Management of relapsed or refractory acute leukemia remains challenging, as allogeneic transplantation is the only curative option. Although targeted therapies are increasingly incorporated as bridge-to-transplant strategies in both AML…
Pei LC, Wang T, Guo YJ et al. · 2026 · BMC pregnancy and childbirth
Background To evaluate the association between triple therapy (hydroxychloroquine sulfate, aspirin, and enoxaparin sodium) and pregnancy outcomes in patients with undifferentiated connective tissue disease (UCTD)-related recurrent…
Karunainathan MG, Lee C, Zohalinejad KD et al. · 2026 · Acta ophthalmologica
Purpose To evaluate real-world safety experience with aflibercept 8 mg in a large case series of patients with neovascular age-related macular degeneration (nAMD). Methods Due to a high proportion of patients on short treatment intervals,…
London KS, Cherney A, Neupane S et al. · 2026 · The American journal of emergency medicine
Background Non-trauma center (NTC) emergency departments (EDs) play regular but underappreciated roles in the management of severely injured patients, yet many lack formal protocols to guide care. We describe the implementation and…
Shirane K, Kitagawa N, Morishima R et al. · 2026 · Journal of pediatric surgery
Background Pulmonary metastasectomy can improve the survival of children with pulmonary metastases from solid tumors. However, preoperative imaging often suggests chest wall and/or mediastinal invasion, raising concerns about…
Teng NMY, Vijayakumar B, Smith DJF et al. · 2026 · Access microbiology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was a global pandemic where infected individuals experienced mild or severe disease. Unfortunately, some patients who experienced severe disease also had lasting abnormalities.…
Gándara-Mireles JA, Reyes Espinoza EA, Loera-Castañeda V et al. · 2026 · Current issues in molecular biology
Doxorubicin (Dox) is a cornerstone in the treatment of pediatric acute lymphoblastic leukemia (ALL), but its use is limited by dose-dependent cardiotoxicity. Oxidative stress, arising from mitochondrial dysfunction, enzymatic generation of…
Szczupak M, Kobak J, Krupa-Nurcek S · 2026 · Frontiers in public health
Introduction Shift work is a recognized occupational risk factor for sleep disturbances, particularly among healthcare professionals. Nurses are especially vulnerable due to irregular work schedules, night duties, and the high physical and…
Zhang Q, Yang T, Li L et al. · 2026 · Neurosurgical review
Chronic internal carotid artery occlusion (CICAO) is a significant cause of ischemic cerebrovascular events, with an annual stroke risk of up to 20%. Although the long-term efficacy of hybrid surgical revascularization (HSR) versus…
Aslan T, AlShamrani M, Buck B et al. · 2026 · Stroke and vascular neurology
Background Stroke rates rise steeply with age but data on tenecteplase in patients ≥80 years remain limited. This post-hoc analysis of the AcT trial compared tenecteplase with alteplase in this population. Methods The analysis included all…