Replication FailureMedicine
He Z, Lyu S, Huang M et al. · 2026 · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery
Objective: To investigate the expression of HPV 6/11 in NIP tissues and evaluate the adjuvant therapeutic effect of interferon-α gel on HPV-positive NIP patients. Methods: Forty-two newly diagnosed Nasal Inverted Papilloma（NIP） patients…
View details →DOI: 10.13201/j.issn.2096-7993.2026.05.011 Negative / Null Result ReportMedicine
Naghizade B, Özyazgan İ, Bozkurt F et al. · 2026 · Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Background Autologous fat grafting is widely used in plastic surgery, but graft survival remains unpredictable, particularly under compromised conditions such as cigarette smoking. Smoking impairs microcirculation and tissue oxygenation,…
View details →DOI: 10.1016/j.bjps.2026.05.060 Negative / Null Result ReportMedicine
Taylor-Williams O, Nossent J, Inderjeeth CA · 2026 · The Journal of rheumatology
Objective Rheumatoid arthritis (RA) is a potentially devastating autoimmune disease associated with multiple comorbidities, including osteoporosis and cardiovascular disease, which exert significant morbidity and mortality burdens. Despite…
View details →DOI: 10.3899/jrheum.2025-0635 Negative / Null Result ReportMedicine
Alkhatatbeh T, Alkhatatbeh A, Liao Y et al. · 2026 · Annals of the New York Academy of Sciences
Intra-articular hyaluronic acid (IAHA) injections are used for knee osteoarthritis, but clinical response is highly variable. This study evaluated whether quantitative magnetic resonance imaging (MRI) radiomics provides incremental…
View details →DOI: 10.1111/nyas.70288 Negative / Null Result ReportMedicine
Schlaepfer CH, Lange SM, Lau GA et al. · 2026 · JAMA pediatrics
Importance People with spina bifida historically have worse survival. Despite health care improvements, survival improvement data are mixed. Objectives To compare survival for people with spina bifida to an unaffected cohort and to…
View details →DOI: 10.1001/jamapediatrics.2026.2241 Negative / Null Result ReportMedicine
Isaacs J, Bendale G, Reiter C et al. · 2025 · Journal of reconstructive microsurgery
Polyethylene glycol (PEG) hydrogel is capable of fusing transected axons and restoring axonal continuity. The technique requires precise nerve coaptation alignment and stability, which is difficult to achieve utilizing conventional…
View details →DOI: 10.1055/a-2737-5393 Negative / Null Result ReportMedicine
Kar N, Rana SS, Gupta R et al. · 2026 · Pancreas
Background and aims Endoscopic ultrasound (EUS)-guided drainage using a lumen-apposing metal stent (LAMS) has become the standard of care in managing symptomatic walled-off necrosis (WON). However, the role of nasocystic drainage (NCD) in…
View details →DOI: 10.1097/mpa.0000000000002659 Negative / Null Result ReportMedicine
Morningstar M, Edwards M, Yang L et al. · 2026 · CJEM
Objectives To systematically identify and describe optimal methodology used to improve the diagnostic accuracy of high-sensitivity cardiac troponin for diagnosis of myocardial infarction in patients with kidney dysfunction. Methods…
View details →DOI: 10.1007/s43678-026-01168-5 Negative / Null Result ReportMedicine
Sroypechr K, Hutchinson C, Satheannoppakao W et al. · 2026 · BMC nutrition
Background The folate status of women of reproductive age (WRA) in Thailand is suboptimal for reducing risk of neural tube defects (NTD). This research aimed to compare the effect of dietary folate education based on the health belief…
View details →DOI: 10.1186/s40795-026-01375-4 Negative / Null Result ReportMedicine
Thurm C, Keating LH, Raja MU et al. · 2026 · Respiratory medicine
Rationale Although low-dose computed tomography (LDCT) performed for lung cancer screening (LCS) frequently identifies previously unrecognized significant incidental findings (SIFs), the most effective way to report these findings remains…
View details →DOI: 10.1016/j.rmed.2026.108955 Negative / Null Result ReportOpen accessMedicine
Hong S, Lee S, Park JS et al. · 2026 · Journal of clinical medicine
Background : We evaluated whether adding S100B to NSE improved discrimination or high-specificity rule-in of poor neurological outcome after out-of-hospital cardiac arrest (OHCA). Methods : In this single-center retrospective cohort study,…
View details →DOI: 10.3390/jcm15083043 Negative / Null Result ReportMedicine
Fesseler L, Patzak A, Heinz V et al. · 2026 · Experimental physiology
High-intensity exercise induces systemic acidosis, which contributes to muscular performance decline. Controlled pre-exercise hyperventilation has been proposed as a non-invasive intervention to induce respiratory alkalosis and counteract…
View details →DOI: 10.1113/ep093393 Negative / Null Result ReportMedicine
Leake HB, Wallwork SB, Moseley GL · 2026 · The journal of pain
Pain science education (PSE) aims to shift unhelpful beliefs about pain and improve clinical outcomes. However, some people report little improvement after receiving PSE-informed care. Understanding their perspectives may help refine…
View details →DOI: 10.1016/j.jpain.2026.106304 Negative / Null Result ReportMedicine
Hongoro DJ, Kengne AP, Peer N et al. · 2026 · AIDS and behavior
Mobile health (mHealth) interventions offer scalable support for adherence and self-management, yet their effects on health-related quality of life (HRQoL) among people living with HIV (PLWH) and comorbid hypertension remain unclear. We…
View details →DOI: 10.1007/s10461-026-05128-z Negative / Null Result ReportMedicine
Yamamoto K, Shinno N, Omori T et al. · 2026 · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
Background Older patients undergoing gastrectomy frequently exhibit sarcopenia and reduced physiologic reserve, increasing vulnerability to perioperative muscle loss. However, randomized evidence supporting multimodal exercise-nutrition…
View details →DOI: 10.1007/s10120-026-01747-6 Negative / Null Result ReportMedicine
Dachy G, Mooyaart JE, Gabellier L et al. · 2026 · Bone marrow transplantation
Lymphodepleting conditioning (LD) with fludarabine and cyclophosphamide is critical to ensure optimal expansion and persistence of CD19 CAR T-cells. We conducted a retrospective EBMT registry study to assess the impact of fludarabine…
View details →DOI: 10.1038/s41409-026-02925-x Negative / Null Result ReportMedicine
Nasr MH, Abdulrasool Hassan B, Othman N et al. · 2026 · Journal of pharmaceutical policy and practice
Background Vitamin D deficiency is common among individuals with type 2 diabetes mellitus (T2DM) and has been linked to insulin resistance and poor glycaemic control. However, findings from randomised controlled trials remain inconsistent.…
View details →DOI: 10.1080/20523211.2026.2680824 Negative / Null Result ReportMedicine
Zorko K, Munda A, Janež A et al. · 2026 · American journal of obstetrics and gynecology
Background Self-monitoring of blood glucose represents the standard for glycemic monitoring in gestational diabetes mellitus, while the role of continuous glucose monitoring remains uncertain. Objective To assess whether adjunctive flash…
View details →DOI: 10.1016/j.ajog.2026.03.030 Negative / Null Result ReportMedicine
Kunz Coyne AJ, Gray R, Gonnabathula P et al. · 2026 · The Journal of antimicrobial chemotherapy
Background Stenotrophomonas maltophilia complex infections are difficult to treat because of intrinsic resistance mediated by the L1 metallo-β-lactamase and L2 serine β-lactamase. Although aztreonam/avibactam is clinically available,…
View details →DOI: 10.1093/jac/dkag177 Negative / Null Result ReportMedicine
Peretz-Kahlon M, Wood K, Harris A et al. · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
BACKGROUND: Branch retinal vein occlusion (BRVO) frequently results in macular edema (ME), impairing visual acuity (VA). Intravitreal anti-vascular endothelial growth factor (VEGF) injections are standard first-line therapy but the benefit…
View details →DOI: 10.1007/s00417-026-07227-y Negative / Null Result ReportMedicine
Mustafa YH, Keogh RJ, Barry SL et al. · 2026 · Irish journal of medical science
Background Glioblastoma is the most common malignant brain tumour in adults and carries a poor prognosis despite advances in molecular characterisation and therapy. The 2021 World Health Organisation classification redefined glioblastoma…
View details →DOI: 10.1007/s11845-026-04449-1 Negative / Null Result ReportMedicine
Arije D, Bista P, Gautam S et al. · 2026 · Field Crops Research.
Cultivated soils in arid and semi-arid regions are vulnerable to soil organic carbon (SOC) loss due to variable crop yields, residue removal, and frequent fallowing. Replacing fallow periods with cover crops has been promoted to increase…
Negative / Null Result ReportMedicine
Yi Y, Yano K · 2025 · Physiologia plantarum
Elevated CO 2 (eCO 2 ) can enhance plant growth, but it may also accelerate senescence, which could offset the growth benefits. Phosphorus (P) supply can enhance the photosynthetic rate under eCO 2 conditions and promote biomass…
View details →DOI: 10.1111/ppl.70470 Negative / Null Result Report
Liang H, Zhang D, An X et al. · 2026 · Preprint
Abstract The rise of generative AI (GenAI) has sparked interest in whether human-AI collaboration can enhance creativity, yet empirical findings remain mixed. This study systematically compared 4 collaboration models (i.e., AI-first,…
View details →DOI: 10.21203/rs.3.rs-8774138/v1 Negative / Null Result ReportMedicine
Gupta N, Seo J, Phan F et al. · 2026 · Heart rhythm
Background Lead dwell time (DT) is associated with increased complexity of cardiac implantable electronic device (CIED) extraction. Optimal strategies for risk mitigation are not well studied. Objective This study aimed to evaluate the…
View details →DOI: 10.1016/j.hrthm.2026.04.025 Negative / Null Result ReportMedicine
Chen YF, Kou HW, Chen TH et al. · 2026 · Journal of gastrointestinal cancer
Purpose Radical surgery is the primary treatment for localized gastric cancer (GC), but the benefit of adjuvant chemotherapy in stage IB GC remains unclear. This study evaluates its impact on recurrence and survival post-gastrectomy.…
View details →DOI: 10.1007/s12029-026-01472-4 Negative / Null Result ReportMedicine
Andrade A, Mureb M, Karaman N et al. · 2026 · Journal of neuro-oncology
PURPOSE: KRAS G12C mutations occur in approximately 11% of non-small-cell lung cancer (NSCLC) patients and are associated with aggressive disease and poor prognosis. Although KRAS G12C-inhibitors are now approved, their impact on Gamma…
View details →DOI: 10.1007/s11060-026-05547-x Negative / Null Result ReportMedicine
Mikami R, Imai S, Hayakawa M et al. · 2025 · Die Pharmazie
This study aimed to evaluate the temporal effect of a serum creatinine (SCr) correction intervention in critically ill patients with daily muscle wasting. A total of 5,355 critical care days in 574 patients with creatinine clearance (Clcr)…
View details →DOI: 10.1691/ph.2025.5569 Negative / Null Result ReportMedicine
Montenegro J, Oliveira CL, Nguyen NK et al. · 2026 · The Journal of nutrition
Background Excess body weight is associated with chronic low-grade inflammation and metabolic abnormalities, such as insulin resistance, and dyslipidemia. Objectives This study aimed to assess the impact of a soy protein-yogurt-honey…
View details →DOI: 10.1016/j.tjnut.2026.101595 Negative / Null Result ReportOpen accessMedicine
Bliesner RK, Stevens AA, Holling L et al. · 2026 · Cureus
Background Being in the large majority, right-handed people are not required to use their nondominant hands throughout their daily lives, resulting in a loss of motor dexterity. As technology continues to advance, improving motor dexterity…
View details →DOI: 10.7759/cureus.108025 