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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19906 results in Negative / Null Result Report · page 620 of 664

Negative / Null Result ReportOpen accessComputer Science

Shaping Ability of Different Single Niti Files: A Cbct Assessment

B. Selivany, A. Yousif · 2020 · The Journal Of Duhok University

Aim : The study aimed to compare Shaping ability of WaveOne Gold, Reciproc Blue and 2Shape NiTi systems having different design and metallurgic properties. Method : Forty five extracted human single root with 10 mm root length were…

View details →DOI: 10.26682/sjuod.2020.23.2.11
Negative / Null Result ReportMedicine

Repeatability and comparability of a new swept-source optical coherence tomographer in optical biometry.

C. E. Monera Lucas, J. Escolano Serrano, C. T. Tarazona Jaimes et al. · 2022 · Archivos de la Sociedad Española de Oftalmología

PURPOSE To evaluate the reproducibility in the measurement of ocular biometric parameters using a new swept-source optical coherence tomographer and its comparability with an optical low coherence reflectometry biometer. DESIGN An…

View details →DOI: 10.1016/j.oftale.2022.04.003
Negative / Null Result ReportOpen accessMedicine

Interleukin-10 polymorphisms in Spanish IgA deficiency patients: a case-control and family study

J. Ortiz, M. Fernández‐Arquero, E. Urcelay et al. · 2006 · BMC Medical Genetics

BackgroundIgA deficiency (IgAD) is the most common primary immunodeficiency in Caucasians. Genetic and environmental factors are suspected to be involved in the development of the disease. Interleukin-10 (IL-10) is a cytokine with…

View details →DOI: 10.1186/1471-2350-7-56
Negative / Null Result ReportOpen accessMedicine

Early stage adrenocortical carcinoma—what contributes to poor prognosis after adrenalectomy? A retrospective cohort study

Douk Kwon, C. Rah, Byung-Chang Kim et al. · 2024 · Annals of Surgical Treatment and Research

Purpose Adrenocortical carcinoma (ACC) is a rare primary carcinoma originating in the adrenal gland with a poor prognosis and a high recurrence rate. This study evaluated the risk factors associated with recurrence in patients with early…

View details →DOI: 10.4174/astr.2024.107.4.187
Negative / Null Result ReportMedicine

Dehorning Does Not Alter the Stress Response in Southern White Rhinoceroses (Ceratotherium simum simum) during Transport: A Preliminary Investigation

Anita Metzinger, Leith C. R. Meyer, P. Buss et al. · 2024 · Journal of Wildlife Diseases

Abstract: Translocation and dehorning are common and important practices for rhinoceros management and conservation. It is not known if dehorning causes a stress response or negatively affects rhinoceroses during transport. Twenty-three…

View details →DOI: 10.7589/jwd-d-23-00061
Negative / Null Result ReportOpen accessMedicine

Ventilation during continuous compressions or at 30:2 compression-to-ventilation ratio results in similar arterial oxygen and carbon dioxide levels in an experimental model of prolonged cardiac arrest

Jukka Kopra, E. Litonius, P. Pekkarinen et al. · 2023 · Intensive Care Medicine Experimental

Background In refractory out-of-hospital cardiac arrest, transportation to hospital with continuous chest compressions (CCC) from a chest compression device and ventilation with 100% oxygen through an advanced airway is common practice.…

View details →DOI: 10.1186/s40635-022-00485-0
Negative / Null Result ReportOpen accessMedicine

Does the Use of Nitroglycerin Patch Improve Local Anaesthetic Effects in Bier's Block? A Double-Blind Placebo Controlled Study

A. Elgebaly · 2018 · Anesthesiology Research and Practice

Aim The aim of the study was to assess the nitroglycerin patch as a new additive to Bier's block and its impact on the effects and dose of lidocaine. Methods Forty patients of each sex belonging to ASA I or II underwent elective tendon…

View details →DOI: 10.1155/2018/9674731
Negative / Null Result ReportMedicine

Effect of Volume on Postoperative Outcomes After Left Pancreatectomy: A Multicenter Prospective Snapshot Study (SPANDISPAN Project)

D. Aparicio-López, J. Ramia, C. Villodre et al. · 2025 · Journal of Clinical Medicine

Background/Objectives: Like many other countries, the management of pancreatic cancer in Spain has developed in a fragmented manner. This study analyzes clinical outcomes related to patient volume at different centers after left…

View details →DOI: 10.3390/jcm14176013
Negative / Null Result ReportOpen accessMedicine

The Effect of Two Calcium Silicate Materials on the Fracture Strength of Simulated Immature Teeth during Regenerative Endodontic Treatment

H. Edrees, A. Y. Siddiqui, M. M. Almousa et al. · 2021 · Journal of Evolution of Medical and Dental Sciences

BACKGROUND Necrotic immature permanent teeth undergoing Regenerative Endodontic Treatment (RET) are subjected to functional forces that might lead to their fracture before achieving apical closure. This study compared the fracture strength…

View details →DOI: 10.14260/jemds/2021/552
Negative / Null Result ReportMedicine

A Half-Century Review of Male and Female Resident Outcomes in Oral and Maxillofacial Surgery: A Single-Institution Report.

Susan Keefe, Carrie Baldwin, Elda Fisher et al. · 2025 · Journal of oral and maxillofacial surgery

BACKGROUND Limited comprehensive historical data exist comparing male and female residents in oral and maxillofacial surgery (OMS) residency programs. This gap underscores the need to examine sex-based differences to guide equitable…

View details →DOI: 10.1016/j.joms.2025.03.011
Negative / Null Result ReportOpen access

Effectiveness of Mechanical Lumbar Traction Positional Variations in Patients with Low Back Pain

G. Murugan, Sheeba Sharon R, A. K. Krishna Kumar · 2023 · International Journal of Health Sciences and Research

BACKGROUND: Low back pain (LBP) is one of the most common causes of disability among the general population. Lumbar traction is an application of distraction force to produce a separation of the joint and elongate the soft tissues.…

View details →DOI: 10.52403/ijhsr.20230217
Negative / Null Result ReportOpen access

Entry Requirements as Predictors of the Academic Performance of Postgraduate Students in Universities in Zimbabwe

Norman Rudhumbu, Patience Kelebogile Mudau · 2022 · International Journal of Learning, Teaching and Educational Research

One of the major strategies that universities use to ensure quality in education is the use of entry requirements as a screening procedure to ensure that only those considered to be the ‘best’ students are admitted. Whether these so-called…

View details →DOI: 10.26803/ijlter.21.2.6
Negative / Null Result ReportOpen accessMedicine

Effectiveness of nano-calcium phosphate paste on sensitivity during and after bleaching: a randomized clinical trial.

A. Loguércio, L. Tay, D. R. Herrera et al. · 2015 · Brazilian Oral Research

The study aimed to evaluate the effectiveness of in-office bleaching and associated tooth sensitivity on application of nano-calcium phosphate paste as desensitizing agent. Bleaching was performed with 35% hydrogen peroxide gel in 40…

View details →DOI: 10.1590/1807-3107bor-2015.vol29.0099
Negative / Null Result ReportMedicine

The Effect of the Lateral First Metatarsal Head Shape on Hallux Valgus in Forced Turnout in Pre-Pointe Female Ballet Dancers: A Pilot Study.

Paul H Doan, David M Handojo, Shivani Parihar et al. · 2024 · Journal of the American Podiatric Medical Association (Print)

BACKGROUND A rounded lateral first metatarsal head shape is associated with higher rates of hallux abducto valgus recurrence following corrective surgery; however, the effect of the lateral first metatarsal head shape on the hallux…

View details →DOI: 10.7547/21-129
Negative / Null Result ReportOpen accessMedicine

A Benchmark Side-by-Side Comparison of Two Well-Established Protocols for in vitro Hematopoietic Differentiation From Human Pluripotent Stem Cells

F. Gutiérrez-Agüera, Virginia C. Rodríguez-Cortez, P. Petazzi et al. · 2021 · Frontiers in Cell and Developmental Biology

The generation of transplantable hematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) remains challenging. Current differentiation protocols from hPSCs generate mostly hematopoietic progenitors of the primitive…

View details →DOI: 10.3389/fcell.2021.636704
Negative / Null Result ReportMedicine

Which clinical factors and biochemical parameters differentiate major depressive disorder with versus without lifetime psychotic symptoms?

C. M. Esposito, F. Legnani, J. Barkin et al. · 2026 · International journal of psychiatry in clinical practice

OBJECTIVE Major depressive disorder (MDD) is a prevalent disabling condition, with psychotic features complicating its course and management. Purpose of the study is to identify clinical and biochemical factors differentiating psychotic…

View details →DOI: 10.1080/13651501.2025.2611928
Negative / Null Result Report

DIALECTIC BEHAVIOUR THERAPYAND ASSERTIVENESS TRAINING IN MANAGING CHALLENGES OF MENTAL HEALTH AMONG ADOLESCENTS WHO ABUSE SUBSTANCES IN PORT-HARCOURT METROPOLIS

Kienka, Kienka, · 2026 · Journal of Professional Counselling

One of the rapidly growing global concerns today is the abuse of various substances that are linked with mental health with significant threat to the psychosocial challenges common in Nigeria. One of the pertinent problems is the…

View details →DOI: 10.61955/iopjof
Negative / Null Result ReportOpen accessPsychology

The Effects of a Structured and Unstructured Kindergarten Program on the Readiness Scores of Children in Selected Public Schools in Lafayette Parish, Louisiana.

Mary Coletta mcdonough Newkome · 1974

The major purpose of this study was to determine if there was a significant difference in readiness test scores between students who participated in a structured kindergarten program and those who participated in an unstructured program.…

View details →DOI: 10.31390/gradschool_disstheses.2684
Negative / Null Result ReportOpen accessMedicine

Evaluation of the Effectiveness and Safety of a Multifaceted Computerized Antimicrobial Stewardship Intervention in Surgical Settings: A Single-center Cluster-randomized Controlled Trial.

Xin Yuan, Kai Chen, Jing Yuan et al. · 2023 · International Journal of Antimicrobial Agents

BACKGROUND Inappropriate antimicrobial use is common for patients undergoing surgery. Whether a multifaceted computerized antimicrobial stewardship program is effective and safe in reducing inappropriate antimicrobial use in surgical…

View details →DOI: 10.1016/j.ijantimicag.2023.106787
Negative / Null Result ReportOpen accessBiology

Effects of new polymorphisms in the bovine myocyte enhancer factor 2D (MEF2D) gene on the expression rates of the longissimus dorsi muscle

E. Juszczuk-Kubiak, R. Starzyński, T. Sakowski et al. · 2012 · Molecular Biology Reports

Myocyte enhancer factor 2D (MEF2D), a product of the MEF2D gene, belongs to the myocyte enhancer factor 2 (MEF2) protein family which is involved in vertebrate skeletal muscle development and differentiation during myogenesis. The aim of…

View details →DOI: 10.1007/s11033-012-1689-6
Negative / Null Result ReportOpen accessChemistry

Trehalose may prevent postsurgical adhesions in a rabbit model of hysterotomy.

H. Fujino, Soojung Lee, Shigeki Suzuki et al. · 2011 · Journal of Veterinary Medical Science

The adhesion-preventing effect of trehalose in visceral organs was evaluated in a rabbit model. All rabbits underwent a hysterotomy, during which mild abrasion and desiccation was induced on the surfaces of visceral organs. In the control…

View details →DOI: 10.1292/jvms.10-0342
Negative / Null Result ReportOpen accessMedicine

Physical activity-related injuries of college students in southern China: A 1-year prospective study

Dongchun Tang, Weicong Cai, Yang Gao et al. · 2020 · Scientific Reports

This prospective study was to describe the incidence and characteristics of physical activity-related injuries (PARI) among college students in southern China. Online questionnaires and telephone interviews were combined to investigate the…

View details →DOI: 10.1038/s41598-020-64317-5
Negative / Null Result ReportOpen accessMedicine

Medical management in locally advanced and metastatic prostate cancer: Does changes in treatment policy have any specific effect on PSA levels?

M. Bağcıoğlu, C. Surcel, S. Ozcan et al. · 2017 · Archivio Italiano di Urologia e Andrologia

OBJECTIVE Androgen deprivation therapy (ADT) is commonly used as a first-line treatment for locally advanced and metastatic prostatic cancer (Pca). There is no consensus about which alternative treatment should be used after the failure of…

View details →DOI: 10.4081/aiua.2017.4.282
Negative / Null Result ReportOpen accessMedicine

No difference in anti-spike antibody and surrogate viral neutralization following SARS-CoV-2 booster vaccination in persons with HIV compared to controls (CO-HIV Study)

Kendall Kling, Patrick Janulis, A. Demonbreun et al. · 2023 · Frontiers in Immunology

Background Understanding the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination will enable accurate counseling and inform evolving vaccination strategies. Little is known about antibody response…

View details →DOI: 10.3389/fimmu.2022.1048776
Negative / Null Result Report

Performance and Carass Potential of Pantaneiro Lambs Supplemented with Saccharomyces cerevisiae

Rafaela Machado dos Santos, Simone Fernanda Nedel Pértile, Marcos Barbosa Ferreira et al. · 2024 · Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde

Abstract The aim of this study was to evaluate the effect of a feed additive for feedlot Pantaneiro lambs on weight gain, dry matter intake, carcass and meat characteristics, in addition to the comparison between males and females. Eleven…

View details →DOI: 10.17921/1415-6938.2024v28n2p203-208