A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21742 results · page 614 of 725
Radha S, Arends M, Kislinger G et al. · 2026 · PLoS biology
Rapid information processing in complex organisms depends on myelin, which consists of a multilamellar membrane that tightly adheres to the axonal surface along the internode and at paranodal loops, where specialized adhesion proteins…
Mirda D, Hao J, Dungan M et al. · 2026 · Cancers
Background : Lynch syndrome (LS) is the most common hereditary cause of colorectal cancer (CRC), and colorectal surveillance has been shown to reduce death from CRC in this high-risk population. This study aimed to examine adherence to…
Ito K, Fujii M, Oba Y et al. · 2026 · International orthopaedics
Purpose To determine changes in low back pain (LBP) after total hip arthroplasty (THA), identify preoperative factors associated with residual LBP and LBP improvement, and clarify the association between residual LBP and patient-reported…
Hamasaki H, Taxiarchi V · 2026 · Preprint
Aims Sarcopenia and sarcopenic obesity are associated with increased risks of cardiovascular (CV) disease and mortality. This study examined the associations of body composition and daily physical activity with mortality, CV events and…
Cunningham PM, Hayes JE · 2026 · Appetite
Widespread nutrition advice instructs consumers to drink water with meals to increase fullness and reduce energy intake. However, recent data indicates greater water intake is associated with more food intake at a meal, not less. Switching…
Charoenrat B, Sungkarat S, Phirawatthakul C et al. · 2026 · BMC geriatrics
Background Neck pain is associated with altered postural and gait performance in older adults. Smartphone use may further challenge postural and gait control due to additional cognitive and motor demands. This study aimed to investigate…
Ediz E, Küçükdağ HN, Özel MA · 2026 · Scientific reports
Although high fructose consumption is known to be associated with metabolic disorders, specific intake thresholds and consumption patterns related to hepatic steatosis have not been fully defined. This study aimed to quantify daily…
Millarch AS, Schøning J, Hjulmand VG et al. · 2026 · The journal of trauma and acute care surgery
Background Opioids have a well-known capacity to induce long-term dependency with related increased morbidity and mortality. Usage patterns following traumatic injury are, however, not well studied. We investigated long-term opioid usage…
de Souza EDF, E Silva LO, Vieira LM et al. · 2026 · Theriogenology
The aim was to evaluate the effects of administering long-acting injectable progesterone (iP4) and/or hCG 3 days after timed artificial insemination (TAI) on luteal dynamics, circulating progesterone (P4) concentrations, and fertility…
Lindhard K, Hansen HP, Gliese K et al. · 2026 · The journal of vascular access
Introduction Improved arteriovenous fistula (AVF) maturation is crucial for reducing the dependency on central venous catheters in patients undergoing hemodialysis (HD). Far-infrared radiation (FIR) is a treatment modality that may enhance…
Kwieciński M, Kwiatkowski B, Ziomek W et al. · 2026 · Molecular biology reports
Despite major advances in medicine, cancer treatment remains a considerable challenge. The rising incidence of new cases and the frequent resistance to cytostatics suggest that standard therapies may be insufficient. This highlights the…
Harcęko-Zielińska E, Górska A, Romantowski J et al. · 2025 · Journal of asthma and allergy
Background The influence of intestinal microorganisms on the development and course of allergic diseases has recently been the subject of intensive research, but studies describing changes in the intestinal microbiome of asthma patients in…
Hoppe C, Hönes GS, Prinz AD et al. · 2025 · Preprint
Background Alcohol-associated liver disease (ALD) is a common type of liver disease worldwide. Excessive consumption of ethanol (EtOH) causes fat accumulation leading to hepatic steatosis. Hepatic thyroid hormone (TH) action or…
Toraño P, Balmaseda A, Bordons A et al. · 2025 · Food microbiology
Oenococcus oeni is the main species of lactic acid bacteria (LAB) responsible for malolactic fermentation (MLF) in winemaking. MLF development can present difficulties because of the harsh, stressful conditions of wine. Yeast mannoproteins…
Roberts E, Francesconi M, Flouri E · 2025 · Stress (Amsterdam, Netherlands)
Prenatal stress has been associated with poor cognitive outcomes in offspring, but the evidence about the role of exact timing of exposure is mixed and that about causal mechanisms is limited. Using the Avon Longitudinal Study of Parents…
Pec J, Nigl M, Fox H et al. · 2026 · Journal of cardiovascular development and disease
(1) Background: Early treatment of sleep-disordered breathing (SDB) with adaptive servo-ventilation (ASV) after acute myocardial infarction (AMI) has been shown to improve myocardial salvage. This analysis evaluates nocturnal…
Hansen EK, Hansen D, Schalkwijk C et al. · 2026 · Blood purification
Introduction Far infrared radiation may improve arteriovenous fistula maturation and patency rates in patients on hemodialysis (HD). The mechanism is proposed to involve anti-inflammatory and vasodilatory effects in the arteriovenous…
Siffredi V, Liverani MC, Fernandez NB et al. · 2025 · Child: care, health and development
Background Very preterm (VPT) adolescents show executive and socio-emotional difficulties that persist into adulthood. Beneficial effect of mindfulness-based intervention (MBI) has been found in VPT young adolescents immediately after the…
Weeks JJ, Johnson PA, Garcia-Tomas V · 2025 · Current opinion in anaesthesiology
Purpose of the review Regional anesthesia is valuable in peripheral vascular surgery, either as the primary anesthetic or as an adjuvant to general anesthesia. Patients presenting for vascular surgery often have associated comorbidities…
Rioux C, Chambaron S, Farineaux E et al. · 2025 · Preprint
Exploring our attitudes towards food is of great interest to identify barriers and opportunities in the consumption of healthy and sustainable products, such as pulses. The present study investigated French adults’ implicit attitudes…
Conteduca J, Longo D, Casto A et al. · 2025 · Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina
Purpose The objective of this study was to assess the benefits of utilizing a silicone ring tourniquet in relation to traditional pneumatic cuff tourniquets and scenarios without any tourniquet intervention. The tested hypothesis…
Ricigliano VA, Szejko N, Camera V et al. · 2026 · Multiple sclerosis and related disorders
Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neuronal loss, with significant public health impact. Despite important therapeutic advances, major unmet needs remain, mainly in…
Terakawa H, Kawata C, Kurokawa Y et al. · 2025 · Gan to kagaku ryoho. Cancer & chemotherapy
Oncotype DX is performed to predict prognosis and the added benefit of chemotherapy in hormone receptor-positive, HER2-negative breast cancer, with the goal of individualizing chemotherapy decisions. Here, we report 2 cases of early- stage…
Singh A · 2026 · Preprint
Abstract Three decades of national-level ICDS evaluation have produced largely inconclusive results at the anthropometric growth parameters of children. This paper argues that this inconclusiveness reflects an aggregation problem:…
Dravigney L, Chartier C, Grelaud P et al. · 2026 · Journal of helminthology
Anthelmintic resistance (AR) in gastrointestinal nematodes is insufficiently studied in cattle in many European regions, including France, where only three studies have been conducted in the north-west. This study evaluated the efficacy of…
Granda D, Szmidt MK, Jarmuzek-Orska P et al. · 2026 · Scientific reports
To date, only a few studies have examined the relationship between dietary patterns and premenstrual syndrome (PMS), and these have been limited to Asian populations with inconclusive results, while studies in European populations are…
Schötz C, White A, Gelbrecht M et al. · 2026 · Chaos (Woodbury, N.Y.)
Predicting chaotic dynamical systems is critical in many scientific fields, such as weather forecasting, but challenging due to the characteristic sensitive dependence on initial conditions. Traditional modeling approaches require…
De Silva DTN, Hamilton AJ, Strunk T et al. · 2026 · European journal of hospital pharmacy : science and practice
Objective To investigate the chemical and visual compatibility of dexmedetomidine injection with 44 secondary intravenous (IV) drugs and six 2-in-1 parenteral nutrition (PN) solutions used in neonatal intensive care unit settings. Methods…
Gurbaxani BM · 2026 · Epidemics
Objectives The COVID-19 pandemic highlighted the need for non-pharmaceutical interventions (NPI) to mitigate hospitalization and death prior to vaccine availability. However, the precise impact of those mitigations have remained…
Giulia C, Simona M, Monia M et al. · 2026 · Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
Background and aims The current diagnostic approach to inherited cardiac conditions (ICCs) is primarily focused on the analysis of single-nucleotide variants (SNVs) and small insertions/deletions (InDels). However, as recommended for other…