Negative / Null Result ReportOpen accessMedicine
Yao H, Chen W, Lin Z et al. · 2026 · Journal of orthopaedic surgery and research
Objective To systematically compare the clinical efficacy and safety of four posterior surgical approaches-olecranon osteotomy (OO), triceps-reflecting approach (TRA), triceps-splitting approach (TS), and triceps tongue approach (TT)-for…
View details →DOI: 10.1186/s13018-026-06739-x Negative / Null Result ReportOpen accessMedicine
Patel DM, Wilson RF, Gharibani T et al. · 2026 · Journal of patient-reported outcomes
BACKGROUND: Patient-reported outcomes (PROs) are key outcomes of importance for people with chronic kidney disease (CKD), and may be of even higher relevance for patients with concomitant anemia which can often be symptomatic. Thus, PROs…
View details →DOI: 10.1186/s41687-026-01007-2 Negative / Null Result ReportOpen accessMedicine
Advani H, Dixit A, Kumar S et al. · 2026 · Cureus
Background Gingival recession (GR) results in significant functional and cosmetic concerns and manifests as a disintegration of soft and hard tissues. Recently, clinical research has increasingly focused on the development of minimally…
View details →DOI: 10.7759/cureus.103991 Negative / Null Result ReportOpen accessMedicine
Zhang Y, Guo M, Bian Q et al. · 2026 · BMC nephrology
Background Primary membranous nephropathy (pMN) is characterized by a prolonged course, frequent relapses, and variable treatment responses. While obinutuzumab (OBI) demonstrates promising efficacy in B-cell depletion, its direct…
View details →DOI: 10.1186/s12882-026-04958-2 Negative / Null Result ReportOpen accessMedicine
Sfulcini M, Trevisi E, Piccioli-Cappelli F et al. · 2026 · PloS one
Weaning represents a critical transition in dairy calves, involving simultaneous dietary, social, and environmental changes. This study investigated how the weaning affects immune-related gene expression in circulating leukocytes of…
View details →DOI: 10.1371/journal.pone.0349643 Negative / Null Result ReportOpen accessMedicine
Mohamed HA, Azer A, AboElHassan RG · 2026 · International journal of dentistry
Background Advanced lithium disilicate glass ceramics offer excellent esthetics, but conservative crown preparations are not always the preferred choice. Various margin designs are available; however, more conservative vertical…
View details →DOI: 10.1155/ijod/5550877 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Lilla Bűdi, Dániel Hammer, Rita Varga et al. · 2025 · Pathology and Oncology Research
ObjectivesSpingosine-1-phosphate (S1P) and ceramides are bioactive sphingolipids that influence cancer cell fate. Anti-ceramide antibodies might inhibit the effects of ceramide. The aim of this study was to assess the potential role of circulating S1P and anti-ceramide antibody as biomarkers in non-small cell lung cancer (NSCLC).MethodsWe recruited 66 subjects (34 controls and 32 patients with NSCLC). Patient history and clinical variables were taken from all participants. Venous blood samples were collected to evaluate plasma biomarkers. If bronchoscopy was performed, bronchial washing fluid
View details →DOI: 10.3389/pore.2024.1611929 Negative / Null Result ReportOpen accessDentistry
Khudhair A Al- Salman, Baydaa A Al-Rawi, Omar S Rahawi · 2012 · Al-Rafidain Dental Journal
Aims: To evaluate the effect of two types of disinfectant solutions(2% alkaline glutaraldehyde, 1% sodium hypochlorite) in wettability of three types of elastomeric impression materials (light body) which are used in crown and bridge restorations at different times of immersion. Materials and me-thods: Three types of elastomeric impression materials (light body) were formed on a flat acrylic resin block and allowed to set(five specimens of each impression material was done for each immersion time(15,30 and60 minutes)of each disinfectant solution in addition to control groups). The wettability
View details →DOI: 10.33899/rden.2012.45454 Negative / Null Result ReportOpen accessPharmacy and materia medica
So-Yeon Kim, Minji Hong, Ponnuvel Deepa et al. · 2023 · Scientia Pharmaceutica
This study aimed to elucidate the anti-inflammatory activity of C. tinctorius leaves by measuring inflammatory parameters such as nitric oxide (NO) production and mRNA expression of iNOS, interleukin-6 (IL-6), and IL-1β in lipopolysaccharide (LPS)-induced HaCaT cells. Further, the effect of C. tinctorius ethanol extract on the MAPKs/NF-κB signaling pathway was examined in HaCaT cells. The phytochemical profile of the ethanol extract of C. tinctorius leaves was determined using UPLC-QTOF-MS/MS. The results indicated that the ethanol extract of C. tinctorius effectively attenuated LPS-induced se
View details →DOI: 10.3390/scipharm91010014 Negative / Null Result ReportOpen accessSports medicine
Blake Bodendorfer, Gary Stover, Christopher Ryan James MD et al. · 2015 · Orthopaedic Journal of Sports Medicine
Objectives: Athletes commonly wear fitted silicone ankle sleeves (SAS) and lace-up ankle braces (LAB). There is limited data about their effect on neuromuscular control or athletic performance. Our goal is to evaluate their efficacy in a young, active population during athletic tasks using motion analysis. Methods: Ten subjects (5 males, 5 females) without prior musculoskeletal injury were recruited. They were asked to perform the Drop Vertical Jump test (DVJ), 45 degree bound, and cutting maneuvers under three conditions: No brace, SAS, LAB. DVJ was used as a surrogate for neuromuscular contr
View details →DOI: 10.1177/2325967115s00042 Negative / Null Result ReportOpen accessZoology
Margaret J. Couvillon, Ginny Fitzpatrick, Anna Dornhaus · 2010 · Psyche: A Journal of Entomology
Bumble bees are important pollinators of crops and other plants. However, many aspects of their basic biology remain relatively unexplored. For example, one important and unusual natural history feature in bumble bees is the massive size variation seen between workers of the same nest. This size polymorphism may be an adaptation for division of labor, colony economics, or be nonadaptive. It was also suggested that perhaps this variation allows for niche specialization in workers foraging at different temperatures: larger bees might be better suited to forage at cooler temperatures and smaller
View details →DOI: 10.1155/2010/536430 Negative / Null Result ReportOpen accessFood processing and manufacture
LIU Chao, ZHAO Liangzhong, WANG Yaoqiong et al. · 2024 · Shipin yu jixie
Objective: Obtaining hhigh-yield pprotease-pproducing bacterial resources through fermentation of advantageous protease-producing strains derived from Shiping stinky tofu. Methods: Single-factor and response surface experiments were used to optimize the culture medium and fermentation conditions. Using casein as the substrate, the effects of temperature, pH, metal ions and organic reagent on the protease activity and stability of strain JX-11 were investigated using enzymology techniques. Results: One strain of high-producing proteinase-secreting bacteria, JX-11, was isolated from Shiping stin
View details →DOI: 10.13652/j.spjx.1003.5788.2023.80813 Negative / Null Result ReportOpen accessMarketing. Distribution of products
Devi Yulia Rahmi, Fikri Alwi, Ratni Prima Lita et al. · 2025 · Journal of Management and Entrepreneurship Research
Objective: The study aims to examine the effect of halal awareness, halal logo, religiosity, and price on consumers' intention to buy food products with a halal logo. This study also examines the effect of purchase intention on consumer purchase behaviour of food products with the halal logo Research Design & Methods: This study uses a quantitative method with 200 respondents who consume food products with the halal logo in West Sumatra. Data were analyzed using the PLS-SEM (Partial Least Square-Structural Equational Modeling) method. Findings: The results of the study show that the halal logo
View details →DOI: 10.34001/jmer.2025.6.06.1-60 Negative / Null Result ReportOpen accessDentistry
Eman Al Mheiri, Jahanzeb Chaudhry, Salma Abdo et al. · 2020 · BMC Oral Health
Abstract Background The aim of this study was to analyze the root and canal morphology of the maxillary permanent first molars in an Emirati population using cone-beam computed tomography (CBCT). Methods Two hundred and sixty-one CBCT scans were acquired. The data were extracted and anonymized to remove all patient identifiers. Two observers (an endodontic resident and an endodontist) evaluated all scans on diagnostic quality monitors. Results The prevalence of a second mesiobuccal canal (MB2) was 80.1% in all examined samples. Type II Vertucci classification, was the most common canal configu
View details →DOI: 10.1186/s12903-020-01269-2 Negative / Null Result ReportOpen accessBiology (General)
Iryna Raievska, Andrii Schogolev · 2024 · Біологічні студії
Background. Morphometric indicators are crucial for evaluating the development and productivity of soybeans. They are influenced by genetic and environmental factors. The use of nearly isogenic soybean lines is a convenient model for determining the impact of early maturity genes and daylength on growth indicators. The aim of this study was to determine the influence of different daylengths and early maturity genes on soybean morphometric indicators under conditions of the temperate zone (at the latitude of Kharkiv – 50° N). Materials and Methods. The study involved nearly isogenic soybean lin
View details →DOI: 10.30970/sbi.1803.784 Negative / Null Result ReportOpen accessPublic aspects of medicine
Hnin Wai Lwin Myo, Akiko S Hosler, Lawrence M Schell et al. · 2023 · Public Health Nutrition
Abstract Objective: The Burmese population is one of the fast-growing refugee populations in the USA. This study investigated behavioural and environmental factors associated with fruit and vegetable (FV) consumption among Burmese refugees. Design: We conducted a cross-sectional interview survey in 2018–2019. The 24-h recall was used to assess dietary behaviour. Multivariable logistic regression models were constructed with meeting the daily FV consumption recommendation (two or more servings of fruits and three or more servings of vegetables) as the outcome variable. We selected socio-economi
View details →DOI: 10.1017/s1368980023000125 Negative / Null Result ReportOpen accessBusiness
Esra Karpuz Demir, Seval Çetinoğlu, Yasemin Deniz Koç · 2026 · Future Business Journal
Abstract This study investigates return and volatility spillovers among the S&P Green Bond Index, S&P Global 1200 Carbon Efficient Index, S&P Global 1200 ESG Index, MAC Global Solar Energy Index, S&P Global Clean Energy Index, MSCI World Index, and MSCI Emerging Markets Index over the period from 30/06/2014 to 22/07/2024. Using a Vector Autoregressive–Exponential Generalized Autoregressive Conditional Heteroskedasticity (VAR-EGARCH) model, the study examines the dynamic interlinkages between sustainable finance indexes, energy markets, and global equity markets. The findings reveal that return
View details →DOI: 10.1186/s43093-026-00882-x Negative / Null Result ReportOpen accessMaterials of engineering and construction. Mechanics of materials
Li Zhou, Bo Chen, Yong Huang · 2022 · Advances in Materials Science and Engineering
To investigate the stress-strain relationship of fiber reinforced phosphogypsum (PG) under uniaxial compression, a total of twenty-seven PG prism specimens were fabricated and tested. The influences of the content of admixture, content of fiber, and water-solid ratio on the stress-strain curve of the specimens were investigated. Three kinds of failure modes were summarized by observing the experimental phenomena; they were called “compaction failure,” “tension failure,” and “mixed stress failure,” respectively. Through in-depth analysis of the test data, it was found that decreasing the water-
View details →DOI: 10.1155/2022/7221491 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Shivani Srivastava, Harsh Pandey, Surya Kumar Singh et al. · 2019 · Advanced Pharmaceutical Bulletin
Purpose: Basically insulin is known to be secreted by β cells of the pancreas. Recently, it has also been found to be produced and expressed by intestinal epithelial cells with the help of L cells secreting glucagon like peptide 1 (GLP 1). Here, we have studied the same intestinal insulin expression property in T2D rats. Methods: Following 2 weeks of high fat diet (HFD) consumption, we have been given a single dose of streptozotocin (STZ) (35 mg/kg bw). Rats were then sacrificed after 1, 7 and 21 days. The GLP 1 analogue, liraglutide was also given to one group of diabetic rats, upto their res
View details →DOI: 10.15171/apb.2019.039 Negative / Null Result ReportOpen accessVeterinary medicine
Narges Sotoudeh, Mohammad Reza Namavar · 2022 · Veterinary Medicine and Science
Abstract Background A combination of ketamine‐xylazine (K‐X) is frequently used for anaesthesia in rats. Sex and age affect this cocktail dosage. Ketamine causes a hypnotic effect by blocking NMDA receptors located on the dendritic spine of the CA1 region. Objectives The present study aimed to find the optimal dosage of K‐X and its association with the changes in dendritic spine number of the CA1 region for aged and young rats of both sexes. Methods We injected 150–4 mg/kg of K‐X in young and 100–2 mg/kg in aged Wistar rats intraperitoneally and recorded the onset time and duration of anaesthe
View details →DOI: 10.1002/vms3.936 Negative / Null Result ReportOpen accessCities. Urban geography
Armand Fréjuis Akpa, Augustin Foster Chabossou · 2024 · Research in Globalization
The introduction of information and communication technology (ICT) has altered the way society operates things. ICT is used in various sectors, including agriculture. It can be used in the agricultural sector to distribute pricing and encourage agricultural commodity exports. The study aims to investigate the effect of ICT on cashew nut export in Benin using an autoregressive distributed lag (ARDL) approach. Data were collected over the period of 31 years (1990–2020) in Benin. The estimated results showed that mobile cellular telephone subscription is negatively and significantly correlated wi
View details →DOI: 10.1016/j.resglo.2024.100197 Negative / Null Result ReportOpen accessOphthalmology
V S Vijitha, Tarjani Vivek Dave, Somasheila I Murthy et al. · 2021 · Indian Journal of Ophthalmology
Purpose: To describe a series of sight-threatening ocular and adnexal involvement associated with dengue hemorrhagic fever and their treatment options. Methods: Retrospective, interventional, non-comparative case series. Medical records of patients who presented with ocular symptoms attributed to dengue hemorrhagic fever were reviewed. Demography, presenting features, and treatment outcomes were recorded. Outcome measures assessed included globe salvage, vision salvage, and visual improvement. The outcome was deemed as favorable if vision salvage was possible and unfavorable if the vision was
View details →DOI: 10.4103/ijo.ijo_1588_20 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Alan J. Weaver, Timothy R. Borgogna, Galen O’Shea-Stone et al. · 2022 · Antibiotics
The rise in bacterial resistance to common antibiotics has raised an increased need for alternative treatment strategies. The natural antibacterial product, 18β-glycyrrhetinic acid (GRA) has shown efficacy against community-associated methicillin-resistant Staphylococcus aureus (MRSA), although its interactions against planktonic and biofilm modes of growth remain poorly understood. This investigation utilized biochemical and metabolic approaches to further elucidate the effects of GRA on MRSA. Prolonged exposure of planktonic MRSA cell cultures to GRA resulted in increased production of staph
View details →DOI: 10.3390/antibiotics11060781 Negative / Null Result ReportOpen accessPublic aspects of medicine
Rob Horne, Caroline Sabin, Trudie Chalder et al. · 2025 · Programme Grants for Applied Research
Background Antiretroviral therapy has transformed human immunodeficiency virus infection intoa chronic condition associated with normal life expectancy. In the United Kingdom, the uptake of antiretroviral therapy is generally high, but a delay in starting antiretroviral therapy and non-adherence compromise the health and well-being of people living with human immunodeficiency virus, increase the risk of transmission of human immunodeficiency virus and increase National Health Service costs. Objectives The overall aim was to improve antiretroviral therapy uptake and adherence by addressing perc
View details →DOI: 10.3310/kppw8401 Negative / Null Result ReportOpen accessScience (General)
Ayodele Owonubi, Favour Kenneth Chiwendu · 2022 · UMYU Scientifica Journal
The objectives of this research were to investigate the nature of pH buffer capacity and evaluate its association selected soil characteristics the study area. Soil samples from ten profile pits from within the study area were collected from genetic horizons. Soil samples were tested in the laboratory for electrical conductivity and pH buffer capacity using standard procedures. Soil data were analyzed using descriptive statistics. One-way analysis of variance and correlation analysis were applied to determine effects and relationships of selected soil properties with soil pH buffer capacity. T
View details →DOI: 10.56919/usci.1222.006 Negative / Null Result ReportOpen accessTechnology
Domagoj Nakić, Katarina Licht, Hana Posavčić et al. · 2025 · Results in Engineering
Increasing amounts of sewage sludge (SS) and phosphorus-induced eutrophication are major global issues, and this study addresses both under a unified approach, by exploring the potential of biochar derived from SS gasification in an experimental plant as an efficient adsorbent for phosphate removal in synthetic wastewater. The key innovation involves the use of a novel biochar, generated as a byproduct of an innovative gasification process, without any additional pretreatment. This approach could help reduce both environmental and economic burdens in potential real-world applications. Pristine
View details →DOI: 10.1016/j.rineng.2025.106077 Negative / Null Result ReportOpen accessAgriculture (General)
A. S. Abdulrhman, Sh. M. M. Al-Atrushy · 2024 · The Iraqi Journal of Agricultural science
This investigation was aimed to study the effect of soil application of Bio health and foliar application with Tecamin max and Benzyl adenine on growth characteristic of sweet orange (Citrus sinensis L.) seedlings during two successive seasons (2020 and 2021). Bio health was added with three concentrations (0, 6 and 12 g.L-1) to the soil and foliar application of Tecamin max with three concentration (0, 5 and 10 ml.L-1), Benzyl adenine with three concentration (0, 100 and 200 mg. L-1) on the sweet orange seedlings which were brought from private nursery in Duhok city and have two- years old an
View details →DOI: 10.36103/w0z2q378 Negative / Null Result ReportOpen accessPsychiatry
Roxoliana Tsisar, Kristen E. Zentner, Katherine Shettell et al. · 2026 · Frontiers in Psychiatry
BackgroundPsychoeducation for families of young adults with psychosis is an evidence-based intervention that alleviates carer burden. The implementation of programming is limited, leaving family carers shouldering a heavy burden without appropriate support.ObjectiveThis pre-post longitudinal pilot study evaluated the preliminary outcomes of a psychoeducational group intervention for family carers of young adults with psychosis, aimed at building skills and reducing carer burden to support recovery in their loved ones.MethodsThe intervention, co-developed and co-facilitated by healthcare profes
View details →DOI: 10.3389/fpsyt.2026.1724396 Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Joanna Hajduk, Cyrill Brunner, Sebastian Malik et al. · 2020 · mAbs
Minor changes in the quality of biologically manufactured monoclonal antibodies (mAbs) can affect their bioactivity and efficacy. One of the most important variations concerns the N-glycosylation pattern, which directly affects an anti-tumor mechanism called antibody-dependent cell-meditated cytotoxicity (ADCC). Thus, careful engineering of mAbs is expected to enhance both protein-receptor binding and ADCC. The specific aim of this study is to evaluate the influence of terminal carbohydrates within the Fc region on the interaction with the FcγRIIIa/CD16a receptor in native and label-free condi
View details →DOI: 10.1080/19420862.2020.1736975 Negative / Null Result ReportOpen accessMedicine (General)
Sepide Ghasemian, Zahra Hojjati Zidashti · 2018 · Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum
Background and Objectives: Iron can play an important role in exercise performance of women. The purpose of the present research was to determine the effects of combined exercise training and Feroglobin supplementation on serum iron and lipid profile in Women with iron deficiency anemia. Methods: In this study, 36 trained females with iron deficiency anemia (mean age, 26.8±6.3 years and body mass index, 19.55±4.4kg/m2) of Lahijan city, were selected as subjects and randomly divided into three groups of supplement+combined training, placebo+combined training, and control. Iron lev
