Negative / Null Result ReportMedicine
Popovic D, Reddy YNV, Omar M et al. · 2025 · Mayo Clinic proceedings
Objective Myeloperoxidase (MPO) is a heme peroxidase that scavenges nitric oxide and contributes to microvascular dysfunction. Patients with heart failure and preserved ejection fraction (HFpEF) have microvascular dysfunction that leads to…
View details →DOI: 10.1016/j.mayocp.2025.02.022 Negative / Null Result ReportOpen accessMedicine
Cohen M, Orgel E, Nevarez-Mejia J et al. · 2025 · EJHaem
Introduction Obesity contributes to poorer clinical outcomes in patients with acute lymphoblastic leukemia. We have shown that adipocytes cause anthracycline resistance by absorbing and metabolizing them into less-active alcohol…
View details →DOI: 10.1002/jha2.70140 Negative / Null Result ReportMedicine
Więcławski W, Smus A, Binder M · 2025 · Vision research
Pupillary light response (PLR) is modulated by the allocation of spatial attention. Larger pupil constrictions for bright stimuli presented on the left side are considered indicative of pseudoneglect, a subtle attentional bias observed in…
View details →DOI: 10.1016/j.visres.2025.108618 Negative / Null Result ReportOpen accessMedicine
Mielniczek M, Lunde P, Grzyb W et al. · 2025 · Journal of functional morphology and kinesiology
Objective: The aim of the study was to investigate the effect of eight weeks of in-season training with wearable resistance attached to the forearm on spike velocity in female volleyball players. Methods: A total of 13 senior female…
View details →DOI: 10.3390/jfmk10040458 Negative / Null Result ReportMedicine
Müller A, Zethof JHT, Pirani C et al. · 2025 · Rhizosphere
Biofilm formation on plant roots is traditionally assumed an important trait for plant growth promoting rhizobacteria, but its importance in the interplay between soil, plant roots and the rhizosphere bacterial and archaeal community is…
Negative / Null Result ReportMedicine
Sasaki AE, Benites NM, Rodrigues B et al. · 2025 · Hearing research
Rodent auditory brainstem neurons undergo substantial electrophysiological maturation during the postnatal period, spanning both pre- and post-hearing phases. These developmental adaptations support high-frequency, temporally precise…
View details →DOI: 10.1016/j.heares.2025.109388 Negative / Null Result ReportOpen accessMedicine
Duong LHK, Lam NV, Tran VT · 2025 · Life (Basel, Switzerland)
Background: Atrial high-rate episodes (AHREs) detected by pacemakers are linked to increased stroke risk. The predictive value of high-sensitivity cardiac troponin I (hs-cTnI) for AHREs in pacemaker patients remains uncertain. This study…
View details →DOI: 10.3390/life15121850 Negative / Null Result ReportOpen accessMedicine
Kim SH, Heo JH, Cunanan K et al. · 2026 · Journal of the Endocrine Society
Context While popular weight-loss medications have raised concerns about lean mass loss, the normative effects of nonpharmacologic weight loss on body composition remain unclear. Objective We assessed how the extent of weight loss from…
View details →DOI: 10.1210/jendso/bvag015 Negative / Null Result ReportMedicine
Parsowith EJ, Herring E, Cohen B et al. · 2025 · Experimental gerontology
Background Over 25% of U.S. older adults experience chronic knee pain, which worsens with inactivity, creating a cycle of pain, disability, and sedentary behavior. However, a limited understanding of the underlying mechanisms hinders the…
View details →DOI: 10.1016/j.exger.2025.112803 Negative / Null Result ReportMedicine
Rubino M, Fan R', Kulesz PA et al. · 2026 · The Laryngoscope
Objectives Complete or relative voice rest is recommended following phonomicrosurgery. Primarily, adherence to rest has been measured using patient reports, but their validity is unknown. Instrumental measures of rest adherence are…
View details →DOI: 10.1002/lary.70432 Negative / Null Result ReportOpen accessMedicine
Bertram AM, Lalot F, van der Werff L et al. · 2025 · Frontiers in psychology
Introduction Many daily situations require rapid judgments about whether information is true or false based on limited information. Prior research has predominantly examined how statement and source characteristics influence these…
View details →DOI: 10.3389/fpsyg.2025.1626047 Negative / Null Result ReportMedicine
Alharbi BM, Williams HE, Parr T et al. · 2025 · Mathematical biosciences
We propose a mathematical model based on coupled ordinary differential equations (ODEs) for metabolite concentrations with the aim of investigating how modifications to the rates affects outputs from a regulatory network. Our aim is to…
View details →DOI: 10.1016/j.mbs.2025.109455 Negative / Null Result ReportMedicine
Poller A, Jha S, Molander L et al. · 2025 · International journal of cardiology
Background It is incompletely understood why patients with takotsubo syndrome (TS) have milder symptoms and a better hemodynamic profile than patients with ST-elevation myocardial infarction (STEMI) despite similar or more extensive…
View details →DOI: 10.1016/j.ijcard.2025.133668 Negative / Null Result Report
López-Moraga A, De Ceuninck M, Van der Heyden Y et al. · 2025 · Preprint
Although avoidance can serve an adaptive function in daily life, excessive or persistent avoidance can form a debilitating symptom of anxiety-related disorders. The transition from adaptive to maladaptive avoidance remains poorly…
View details →DOI: 10.1101/2025.02.28.640742 Negative / Null Result ReportOpen accessMedicine
Sencan A, Dundar N, Gunel B et al. · 2025 · Medeniyet medical journal
Objective To compare mechanical power (MP) levels among flow-controlled ventilation (FCV), volume-controlled ventilation (VCV), and pressure-controlled volume-guaranteed ventilation (PCV-VG) during laparoscopic surgery and to test the…
View details →DOI: 10.4274/mmj.galenos.2025.66664 Negative / Null Result ReportMedicine
Wesolowski LT, DiSilvestro AN, Williams BD et al. · 2025 · Journal of equine veterinary science
Disruption of circadian rhythms contributes to a myriad of health issues. Rhythms can be strengthened using artificial light but whether optimal light patterns support health parameters in horses is unknown. To test the hypothesis that…
Negative / Null Result ReportMedicine
Rau J, Joseph R, Weise L et al. · 2025 · Journal of neurotrauma
Previous studies have shown that administration of high doses of morphine in the acute phase of spinal cord injury (SCI) significantly undermines locomotor recovery and increases symptoms of chronic pain in a rat spinal contusion model.…
View details →DOI: 10.1089/neu.2024.0375 Negative / Null Result ReportMedicine
Pleau J, Tanguay N, Courtemanche Y et al. · 2025 · Maternal and child health journal
Objectives The objectives of this study are to describe cannabis use during pregnancy, identify associated factors, examine the associations between prenatal cannabis use and the cognitive, motor and language development of 2-year-old…
View details →DOI: 10.1007/s10995-025-04077-8 Negative / Null Result ReportMedicine
Quaedflieg CWEM, Ashton SM, Beckers T et al. · 2025 · Journal of behavior therapy and experimental psychiatry
Fear is a universal experience and fuels our response to cope with threat. Persistent fear, after the threat is no longer present, is a central symptom seen in a number of clinical conditions. Exposure therapy, the most common treatment to…
View details →DOI: 10.1016/j.jbtep.2025.102018 Negative / Null Result Report
van Berlo E · 2024 · Preprint
In this study, we investigated how spatial, temporal, and effort dimensions collectively influence reward discounting across different age groups. Using a 3D simulated environment, participants aged 7 to 77 chose between a nearby tree with…
View details →DOI: 10.31234/osf.io/grv5w Negative / Null Result Report
Lazar R, Fazlali F, Dourte M et al. · 2024 · Preprint
Whether light exposure during the day reduces non-visual light effects later in the evening has not been studied in adolescents. We investigate whether afternoon-early evening (AEE) light interventions (130 lx, 2500 lx, 4.5 hours, compared…
View details →DOI: 10.1101/2024.10.02.616112 Negative / Null Result Report
Vidal V, Pretel MR, Capurro L et al. · 2024 · Preprint
Abstract The application of neuroscience findings in educational settings offers promising opportunities to enhance academic performance. Adolescents, particularly affected by delayed sleep patterns due to early school start times, often…
View details →DOI: 10.21203/rs.3.rs-5485881/v1 Negative / Null Result Report
Molloy M, McLennan E, Fox S et al. · 2024 · Preprint
The gut microbiome is an important component of host health and function and is influenced by internal and external factors such as host phylogeny, age, diet, and environment. Monitoring the gut microbiome has become an increasingly…
View details →DOI: 10.22541/au.172969938.82154815/v1 Negative / Null Result ReportOpen accessMedicine
Hidding M, van der Stouwe E, Rosema BS et al. · 2025 · Psychological medicine
Background Low self-esteem is an important and potentially modifiable risk factor for the development and outcome of psychotic disorders. The factors involved in low self-esteem in psychotic disorders are not yet fully understood. The…
View details →DOI: 10.1017/s0033291725102857 Negative / Null Result ReportOpen accessMedicine
Nam J, Bellinger GC, Li J et al. · 2025 · JMIR cardio
Background Wearable activity monitors offer clinicians and researchers accessible, scalable, and cost-effective tools for continuous remote monitoring of functional status. These technologies can complement traditional clinical outcome…
View details →DOI: 10.2196/70007 Negative / Null Result Report
van Berlo E, Hausfeld J, Engelmann JB et al. · 2024 · Preprint
In this study, we investigated how spatial, temporal, and effort dimensions collectively influence reward discounting across different age groups. Using a 3D simulated environment, participants aged 7 to 77 chose between a nearby tree with…
View details →DOI: 10.31234/osf.io/asd7k Negative / Null Result Report
Angeletos Chrysaitis N, Seriès P · 2024 · Preprint
Bayesian studies of perception have documented how the brain learns the statistics of a new environment and uses them to interpret sensory information. Impairments in this process have been hypothesised to be central to autism spectrum…
View details →DOI: 10.1101/2024.07.12.603256 Negative / Null Result ReportOpen accessMedicine
Liu X, Zheng W, Hoon L et al. · 2026 · Npj mental health research
Smartphone-delivered interventions offer a scalable solution for university students experiencing depression, yet outcomes remain inconsistent. This study examined predictors of depression remission and response in the AI-enhanced Vibe Up…
View details →DOI: 10.1038/s44184-026-00208-3 Negative / Null Result ReportOpen accessMedicine
Bakhshinejad JA, Watkins CM, Pelton LM et al. · 2026 · International journal of exercise science
The primary aim of this investigation was to examine the effects of three drop jumps (DJ) on mean velocity (m/s) of subsequent deadlifts at various percentages of 1 RM. A secondary exploratory aim was to evaluate whether protocol order,…
View details →DOI: 10.70252/ijes2026105 Negative / Null Result ReportOpen accessMedicine
Lewandowski KE, Luo J, Yao B et al. · 2025 · Frontiers in psychiatry
Introduction Motivational impairments are a hallmark symptom of psychotic disorders. However, motivation is a multidimensional construct believed to be underpinned by different neural mechanisms and differentially impaired both between and…
View details →DOI: 10.3389/fpsyt.2025.1485460 