Methods Dead-EndOpen accessMedicine
Some DY, Kiemde F, Kabore B et al. · 2026 · PloS one
Objective To evaluate the field accuracy of a malaria diagnostic algorithm combining sequential interpretation of two-step malaria RDT detecting PfHRP2 and pLDH with information on previous antimalarial treatments within the past four…
View details →DOI: 10.1371/journal.pone.0351990 Failed Experiment ReportOpen accessMedicine
He X, Kratochwil N, Ariño-Estrada G et al. · 2026 · Physics in medicine and biology
Positron emission tomography (PET) image quality is partially determined by PET detector performance, which can be improved by increasing the optical photon harvest from scintillator to photodetector. Due to the steep index mismatch at…
View details →DOI: 10.1088/1361-6560/ae752d Replication FailureOpen accessMedicine
Painter C, Phommasone K, Mayxay M et al. · 2026 · BMJ public health
Introduction In many low- and middle-income countries, there is widespread use of point-of-care tests (POCTs) to diagnose a variety of infectious diseases, even in hospitals due to weak laboratory capacity. Often, POCT use is unregulated…
View details →DOI: 10.1136/bmjph-2025-003523 Failed Experiment ReportOpen accessMedicine
Adepoju D, Ohlsson JI, Klingström T et al. · 2026 · Genetics, selection, evolution : GSE
Background In genetic terms, the history of a population can be described by its effective population size over time. We know that domestic cattle have gone through dramatic changes in recent history, including intensifying selection in…
View details →DOI: 10.1186/s12711-026-01050-z Methods Dead-EndMedicine
de Andrade Filho PH, da Silva Souza Barbosa R, Tafner GP et al. · 2026 · Journal of clinical anesthesia
Background The pericapsular nerve group (PENG) block has emerged as an effective regional anesthesia technique for managing hip pain, offering substantial analgesia while preserving motor function. However, the minimum effective volume…
View details →DOI: 10.1016/j.jclinane.2026.112267 Methods Dead-EndMedicine
Hirsch W, Enns EA, Khoruts A et al. · 2026 · Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Background Fecal microbiota transplantation (FMT) is the cost-effective strategy for managing recurrent Clostridioides difficile infection (rCDI). Prior costing models assumed FMT administration via colonoscopy. With the commercialization…
View details →DOI: 10.1093/cid/ciag263 Negative / Null Result ReportMedicine
Lubberink M, Åhlström A, Tolvanen T et al. · 2026 · Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Purpose Previously published effective dose coefficient estimates for 15 O-water are around 1 μSv/MBq, resulting in an effective dose of around 0.4 mSv for a typically injected activity of 400 MBq in clinical cardiac scans. These estimates…
View details →DOI: 10.1016/j.nuclcard.2026.102775 Negative / Null Result ReportMedicine
Cloonan MR, Maginot ER, Tieken KR et al. · 2026 · Journal of surgical education
To determine the frequency of nontechnical skills (NTS) feedback provided by attending surgeons through narrative comments and assess its effectiveness using a validated formative feedback rubric. This retrospective cross-sectional study…
View details →DOI: 10.1016/j.jsurg.2026.104035 Negative / Null Result ReportOpen accessMedicine
Huang J, Ye H, Lin J et al. · 2026 · PloS one
Background The cost-effectiveness of liposome irinotecan (II) (HR070803) in combination with 5-fluorouracil and leucovorin as a treatment for patients with locally advanced or metastatic pancreatic ductal adenocarcinoma offering a…
View details →DOI: 10.1371/journal.pone.0351853 Null DatasetOpen accessMedicine
Eid AM, Mabrouk WM, Amer M et al. · 2026 · Scientific reports
Accurate reservoir characterization in structurally complex fields is essential for optimizing hydrocarbon exploration and production. This study presents a detailed analysis of the AEB-3E reservoir within the Berenice Oil Field. It…
View details →DOI: 10.1038/s41598-026-53328-3 Negative / Null Result ReportMedicine
Cheng X, Huang H, Fan Z et al. · 2026 · BMJ open ophthalmology
Objective To evaluate the efficacy and safety of portable, cost-effective manual thermal pulsation as a single therapy for meibomian gland dysfunction (MGD) and to compare the microbiota and lipid composition in subjects with different…
View details →DOI: 10.1136/bmjophth-2026-002769 Negative / Null Result ReportMedicine
Hayman NT, Pandelides Z, Colvin MA et al. · 2026 · Environmental toxicology and chemistry
A lack of marine specific data results in challenges to assessing site-specific ecological risks and developing marine water quality criteria for per- and polyfluoroalkyl substances (PFAS). Here, the toxicity and bioaccumulation of…
View details →DOI: 10.1093/etojnl/vgag168 Negative / Null Result ReportMedicine
De Groote W, Taremwa Y, Duttine A et al. · 2026 · International journal of environmental research and public health
In Uganda, in 2019, 6.8 million people experienced health conditions that are amenable to rehabilitation. This is largely due to musculoskeletal disorders such as low back pain (LBP). Measuring effective coverage of rehabilitation means…
View details →DOI: 10.3390/ijerph23060693 Negative / Null Result ReportMedicine
Aljuaid M, Alsiraj K · 2026 · Annals of the ICRP
This is a national study about the occupational Radiation doses for medical workers in the Kingdom of Saudi Arabia which covers the period since the establishment of the Nuclear and Radiological Regulatory Commission (NRRC). The study aims…
View details →DOI: 10.1177/01466453251411988 Negative / Null Result ReportOpen accessMedicine
Büyüksefil M, Çimen Ü, Şimşek Derelioğlu S et al. · 2026 · Oral health & preventive dentistry
Purpose Effective communication with paediatric patients is one of the cornerstones of paediatric dentistry. Strong communication skills play a critical role in reducing dental anxiety, enhancing patient satisfaction, and facilitating the…
View details →DOI: 10.3290/j.ohpd.c_2680 Negative / Null Result ReportMedicine
Choi JY, Song WS, Won YK et al. · 2026 · Korean journal of ophthalmology : KJO
Purpose To compare the effective phacoemulsification time used in cataract surgery and postoperative outcomes between the Veritas and the Centurion Vision System. Methods A retrospective analysis was conducted on 90 eyes from 82 patients…
View details →DOI: 10.3341/kjo.2025.0196 Negative / Null Result ReportMedicine
Jacobs S, Edelhoff H, Ebert C et al. · 2026 · BMC ecology and evolution
Effective population size (Ne) is a fundamental parameter in conservation genetics, providing relevant information on the adaptability and long-term viability of populations. In contrast, wildlife management strategies, particularly for…
View details →DOI: 10.1186/s12862-026-02543-7 Negative / Null Result ReportMedicine
Leung A, Koo J · 2026 · CNS drugs
Dermatological delusional disorders, such as delusional infestation (DI), are a unique type of psychosis in which the patient experiences specific delusions, such as parasites or inorganic materials that come out of their skin. Originally,…
View details →DOI: 10.1007/s40263-026-01309-5 Negative / Null Result ReportMedicine
Cherif IS, Essis EML, Diallo MA et al. · 2026 · Case reports in infectious diseases
Background Lassa fever is a potentially fatal viral hemorrhagic disease caused by a ribonucleic acid (RNA) virus of the Arenaviridae family, endemic in West Africa. It is highly virulent and contagious in several countries, with a…
View details →DOI: 10.1155/crdi/2672939 Negative / Null Result ReportMedicine
Columbo JA, Scali ST, Wanhainen A et al. · 2026 · Annals of surgery
Objective To determine the contemporary cost per quality-adjusted life year(QALY) gained for abdominal aortic aneurysm (AAA) repair in current practice and assess the optimal threshold for intervention. Summary background data The widely…
View details →DOI: 10.1097/sla.0000000000007134 Failed Experiment ReportMedicine
Ilbag P, Rismanchian M, Yazdanirad S · 2026 · Scientific reports
The purpose of using electroplating is the high cost of corrosion of metal equipment. However, the dangers of this process are the basis for using industrial hygiene control methods in this industry. The aim of this study is to…
View details →DOI: 10.1038/s41598-026-42541-9 Negative / Null Result ReportMedicine
Sabzehei S, Innocenti N, Rigoli M et al. · 2026 · Expert opinion on drug discovery
Introduction Prion diseases are rare, fatal neurodegenerative disorders caused by the conformational conversion of cellular prion protein (PrP) into a pathogenic counterpart called PrP Sc , that replicates by templated misfolding. The…
View details →DOI: 10.1080/17460441.2026.2688321 Negative / Null Result Report
S M, K Mk, K S · 2026 · Preprint
Abstract Industrial discharge from the textile and dyeing industries in Tamil Nadu’s Tiruppur district has severely contaminated the soil with heavy metals, posing significant ecological and human health risks. This study assesses…
View details →DOI: 10.21203/rs.3.rs-9582376/v1 Failed Experiment ReportMedicine
Ducharme MT, Elmenawi KA, Poilvache H et al. · 2026 · The Journal of arthroplasty
Introduction Periprosthetic joint infections (PJI) are complex to manage and frequently result in prolonged hospitalization while awaiting outpatient antibiotic therapy coordination. Moving this work to the preoperative setting for…
View details →DOI: 10.1016/j.arth.2026.06.025 Negative / Null Result ReportOpen accessMedicine
Ran X, Shang Y, Yang X et al. · 2026 · Lasers in medical science
To investigate whether noninvasive reflectance confocal microscopy (RCM)-derived vascular parameters can serve as objective predictors of therapeutic response to pulsed dye laser (PDL) treatment in patients with port wine stain (PWS),…
View details →DOI: 10.1007/s10103-026-04906-4 Negative / Null Result ReportOpen accessMedicine
Yu XQ, Drzymalski DM, Qian J et al. · 2026 · Drug design, development and therapy
Background Left uterine displacement is presumed to decrease vasopressor requirements during cesarean delivery due to decreased aortocaval compression, but studies have been equivocal. Our primary aim was to determine the median effective…
View details →DOI: 10.2147/dddt.s591446 Methods Dead-EndMedicine
Chopra AA, MacLeod JS, Compton TM et al. · 2026 · Clinical spine surgery
Study design Break-even cost analysis. Objectives This study uses a break-even cost-effectiveness model to assess whether enoxaparin is cost-effective for venous thromboembolism (VTE) prophylaxis in patients undergoing posterior lumbar…
View details →DOI: 10.1097/bsd.0000000000002102 Negative / Null Result ReportMedicine
Fabbri F, Albusaidi I, Ntani G et al. · 2026 · Occupational medicine (Oxford, England)
Background Hand dermatitis is a common occupational skin disease and is particularly prevalent among healthcare workers. Aims To identify which digital skin surveillance methods are effective for detecting hand dermatitis. Methods A…
View details →DOI: 10.1093/occmed/kqag028 Methods Dead-EndOpen accessMedicine
Nduka IJ, Okafor CE, Ekwunife OI · 2026 · PloS one
Mammography still remains the gold standard for breast cancer screening, considering its impact on breast cancer mortality. However, it has a relatively low utilization rate in Nigeria. Although the National Strategic Cancer Control Plan…
View details →DOI: 10.1371/journal.pone.0351492 Negative / Null Result ReportOpen accessMedicine
Rotter JM, Seifert R · 2026 · European journal of clinical pharmacology
Purpose Drug supply shortages are a recurring issue in developed countries, with consequences for patients even before the COVID-19 pandemic. Questions arise regarding the effectiveness and tolerability of alternative treatments chosen by…
View details →DOI: 10.1007/s00228-026-04052-4 