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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 598 of 725

Negative / Null Result ReportMedicine

Task Instructions Significantly Affect Maximum Phonation Time.

Baker CP, Miles A, Allen J · 2026 · Journal of voice : official journal of the Voice Foundation

Introduction Maximum phonation time (MPT) is a widely used clinical measure for assessing the effects of voice disorder on vocal function as well as pre-/post-treatment effects. Although its cost-effective nature makes MPT an appealing…

View details →DOI: 10.1016/j.jvoice.2026.05.024
Negative / Null Result ReportMedicine

Exploring ethical reasoning and welfare perceptions of <i>Octopus vulgaris</i> paralarvae among scientific and non-scientific communities.

Monnissen J, De Block A · 2026 · Laboratory animals

Live cephalopods used in scientific research are protected under European Directive 2010/63/EU due to growing evidence that adult cephalopods can experience pain. This protection also extends to paralarval Octopus vulgaris , despite the…

View details →DOI: 10.1177/00236772261441121
Negative / Null Result ReportMedicine

Comparative assessment of behavioural alterations induced by common laboratory solvents in zebrafish (Danio rerio) larvae.

Vujović T, Begić Biškup K, Bojanić K et al. · 2026 · Scientific reports

Organic solvents are routinely used to dissolve poorly water-soluble chemicals in zebrafish-based assays. However, their intrinsic biological activity may confound behavioural endpoints and compromise data interpretation. This study…

View details →DOI: 10.1038/s41598-026-59476-w
Negative / Null Result ReportMedicine

Multiple-Birth Family Knowledge in Maternity and Child Health Clinics: Filling Knowledge Gaps to Improve Multiple-Birth Family Nursing.

Heinonen K, Kaprio J, Trias T et al. · 2026 · Twin research and human genetics : the official journal of the International Society for Twin Studies

The purpose of this cross-sectional study was to investigate knowledge about multiple-birth families among midwives and public health nurses working in maternity and child health clinics in Finland. The data were collected with a Finnish…

View details →DOI: 10.1017/thg.2026.10055
Negative / Null Result ReportMedicine

Neurocognitive Function, Cerebral Blood Flow, and Hippocampal Volume After Catheter Ablation of Atrial Fibrillation.

Yamamoto T, Takahashi Y, Takagi S et al. · 2026 · JACC. Clinical electrophysiology

Background The effect of atrial fibrillation (AF) catheter ablation on neurocognitive function is debated. Objectives This study sought to investigate changes in cognitive function and brain imaging after AF ablation. Methods Patients…

View details →DOI: 10.1016/j.jacep.2025.12.037
Negative / Null Result ReportMedicine

Sociodemographic Factors Associated With Postpartum Readiness: A Survey Study.

McHugh EG, Marudo C, Safvati N et al. · 2026 · The Journal of perinatal education

The postpartum period is pivotal for both maternal and infant well-being, yet factors influencing postpartum readiness remain underexplored. This study investigates these factors with an emphasis on the impact of perinatal educators on…

View details →DOI: 10.1891/jpe-2024-0031
Negative / Null Result ReportMedicine

Absence of osteoclastogenic response to pooled polyclonal anti-citrullinated peptide/protein antibodies from patients with rheumatoid arthritis in vitro.

Chen X, An Z, Li C et al. · 2026 · Clinical and experimental medicine

Anti-citrullinated peptide/protein antibodies (ACPAs) are specific serological markers for rheumatoid arthritis (RA), but their direct role in promoting osteoclastogenesis remains controversial. This study aims to determine whether…

View details →DOI: 10.1007/s10238-026-02208-1
Negative / Null Result ReportMedicine

The efficacy of tranexamic acid in prevention and treatment of post-inflammatory hyperpigmentation: a pilot study.

Masood M, Lane B, Maghfour J et al. · 2026 · Clinical and experimental dermatology

Post-inflammatory hyperpigmentation (PIH) is a common complication following trauma or cutaneous inflammation, particularly affecting individuals with skin of colour. Tranexamic acid (TXA) is a lysine analogue with antifibrinolytic…

View details →DOI: 10.1093/ced/llag082
Negative / Null Result ReportMedicine

The impacts of public hospital compensation reform on the health workforce compensation and its structure: quasi-experimental evidence in China.

Zhao Y, Peng Z, Cao D et al. · 2026 · BMC health services research

Background The Chinese government piloted the public hospital's compensation system reform in 2017. It is important for policymakers to understand how this reform has affected the health workforce's compensation and its structure. We…

View details →DOI: 10.1186/s12913-026-14850-2
Negative / Null Result ReportMedicine

Beta cell function and insulin sensitivity during elexacaftor/tezacaftor/ivacaftor therapy in people with cystic fibrosis.

Zazzeron L, Grancini V, Trombetta M et al. · 2026 · Frontiers in endocrinology

Background Cystic fibrosis-related diabetes (CFRD) is the most common extra-pulmonary complication in adults with cystic fibrosis (CF) and is primarily driven by progressive beta-cell dysfunction. The impact of CFTR modulators,…

View details →DOI: 10.3389/fendo.2026.1774728
Negative / Null Result ReportMedicine

The renin angiotensin system in cognitive flexibility: Effects of single-dose losartan on task-switching in healthy volunteers.

Prasad D, Feltham G, De Giorgi R et al. · 2026 · Journal of psychopharmacology (Oxford, England)

Introduction Cognitive flexibility, defined as the ability to shift mental strategies when environmental demands change, may influence psychological well-being and psychiatric treatment outcomes. Research increasingly implicates the renin…

View details →DOI: 10.1177/02698811261456198
Negative / Null Result ReportMedicine

Pharmacokinetic Assessment of Atazanavir and Favipiravir Following Echinacea Supplementation: A Controlled Herb-Drug Interaction Investigation.

Gajula SNR, Kallam JS, Kanukolanu A et al. · 2026 · Biopharmaceutics & drug disposition

Echinacea is a widely used herbal supplement and is frequently co-administered with antiviral drugs, raising concerns regarding potential herb-drug interactions. This study evaluated the effect of repeated Echinacea administration on the…

View details →DOI: 10.1002/bdd.70034
Negative / Null Result ReportMedicine

Multitasking Across Physical and Virtual Displays: The Effect of Spatial Discontinuity and Task Load.

Zhang P, Iskandarani ME, Riggs S · 2026 · IEEE transactions on visualization and computer graphics

Optical see-through head-mounted displays (OST-HMDs) allow users to interact with both physical and virtual displays overlaid in the real world within augmented reality (AR) environments. When arranging these displays in space, spatial…

View details →DOI: 10.1109/tvcg.2026.3679118
Negative / Null Result ReportMedicine

Broiler response to partial replacement of groundnut cake with soaked chickpea (Cicer arietinum L.) and enzyme supplementation.

Ahmed ME, Mahjoub SMAH, Adam SIY · 2026 · Tropical animal health and production

This study evaluated the effects of partially replacing groundnut cake with soaked chickpea (Cicer arietinum L.) seeds, with or without enzyme supplementation, on growth performance, carcass traits, serum biochemical indices, and…

View details →DOI: 10.1007/s11250-026-05146-y
Negative / Null Result Report

Effects of Substituting Dietary Ryegrass with Licorice Residue on Growth Performance, Meat Quality, Serum Biochemistry and Cecal Microbiota of Rabbits

Ren X, Wu Q, Zhao M et al. · 2026 · Preprint

This research aimed to determine the effects of replacing ryegrass (Lolium perenne L.) with licorice residue (LR) on growth performance, slaughtering performance, meat quality, serum biochemistry and cecal flora. Five pelleted rations were…

View details →DOI: 10.20944/preprints202605.1776.v1
Negative / Null Result Report

Investigation of the Effect of Different Glide Path Files on Canal Transportation and Centering in Curved Root Canals – A Micro-Computed Tomography Study

Uğurlu T, Sağlam BC, Koçak S et al. · 2026 · Preprint

Abstract Background The aim of this in vitro study was to examine the effects of different glide path files on root canal transportation and centering in curved root canals. Methods In this study, 33 mandibular first molars with a 10 mm…

View details →DOI: 10.21203/rs.3.rs-9516903/v1
Negative / Null Result ReportMedicine

Mechanisms Linking Bonding and Bridging Social Capital and Self-Rated Health Among U.S. Refugees: A Structural Equation Modeling Approach.

Thapa K, R Iyer A, A Cruz-Gonzalez M et al. · 2026 · Journal of racial and ethnic health disparities

Background Refugees often experience disruptions in social networks after resettlement. This study examined associations between bonding (within-group) and bridging (across-group) social capital and self-rated health among resettled U.S.…

View details →DOI: 10.1007/s40615-026-03052-5
Negative / Null Result ReportMedicine

Diagnostic value of 18F-FDG PET/CT and MRI in patients suspected of cancer of unknown primary in the head and neck.

Mathiesen KK, Rasmussen JH, Channir H et al. · 2026 · Acta oto-laryngologica

Background Cancer of unknown primary (CUP) is diagnostically challenging. Diagnostic strategy remains controversial. Aim The aim of this retrospective study was to evaluate the diagnostic value of FDG-PET/CT and MRI in detecting primary…

View details →DOI: 10.1080/00016489.2025.2612018
Negative / Null Result ReportMedicine

Effects of xylazine on blood biochemical, oxidative, and haematological to responses to transport distance stress in day-old broiler chicks.

Abdulameer HS, Zarrinkavyani K, Fathi M et al. · 2026 · Poultry science

Transport of day-old chicks is a major concern in the poultry industry, as it induces stress that can impair performance and health. This study investigated whether xylazine, an alpha-2 adrenergic agonist that reduces metabolic rate, could…

View details →DOI: 10.1016/j.psj.2026.107191