Negative / Null Result ReportOpen accessMedicine
Fiske M, DiDomenico DL, Chase HW et al. · 2026 · Bipolar disorders
Objectives Bipolar Disorder (BD)-characterized by mania, affective lability, and elevated psychosis risk-is associated with sustained attention deficits. However, evidence regarding performance on the AX-Continuous Performance test task…
View details →DOI: 10.1111/bdi.70129 Negative / Null Result Report
Fan S, Liao D, Su X et al. · 2026 · Preprint
Abstract Hip fracture, a severe complication of osteoporosis, imposes a heavy burden on aging populations. Evidence on the association between the total cholesterol to high-density lipoprotein cholesterol (TC/HDL-C) ratio and hip fracture…
View details →DOI: 10.21203/rs.3.rs-9668455/v1 Negative / Null Result ReportMedicine
Baker CP, Miles A, Allen J · 2026 · Journal of voice : official journal of the Voice Foundation
Introduction Maximum phonation time (MPT) is a widely used clinical measure for assessing the effects of voice disorder on vocal function as well as pre-/post-treatment effects. Although its cost-effective nature makes MPT an appealing…
View details →DOI: 10.1016/j.jvoice.2026.05.024 Negative / Null Result Report
Şeker YK, Büyükerkmen EB · 2026 · Preprint
Abstract Objectives: This study evaluated the trueness of virtual interocclusal records (VIR) obtained using three acquisition strategies with four intraoral scanners by means of three-dimensional comparison with a laboratory reference…
View details →DOI: 10.21203/rs.3.rs-9306598/v1 Negative / Null Result ReportMedicine
Monnissen J, De Block A · 2026 · Laboratory animals
Live cephalopods used in scientific research are protected under European Directive 2010/63/EU due to growing evidence that adult cephalopods can experience pain. This protection also extends to paralarval Octopus vulgaris , despite the…
View details →DOI: 10.1177/00236772261441121 Negative / Null Result ReportMedicine
Vujović T, Begić Biškup K, Bojanić K et al. · 2026 · Scientific reports
Organic solvents are routinely used to dissolve poorly water-soluble chemicals in zebrafish-based assays. However, their intrinsic biological activity may confound behavioural endpoints and compromise data interpretation. This study…
View details →DOI: 10.1038/s41598-026-59476-w Negative / Null Result ReportMedicine
Heinonen K, Kaprio J, Trias T et al. · 2026 · Twin research and human genetics : the official journal of the International Society for Twin Studies
The purpose of this cross-sectional study was to investigate knowledge about multiple-birth families among midwives and public health nurses working in maternity and child health clinics in Finland. The data were collected with a Finnish…
View details →DOI: 10.1017/thg.2026.10055 Negative / Null Result ReportMedicine
Yamamoto T, Takahashi Y, Takagi S et al. · 2026 · JACC. Clinical electrophysiology
Background The effect of atrial fibrillation (AF) catheter ablation on neurocognitive function is debated. Objectives This study sought to investigate changes in cognitive function and brain imaging after AF ablation. Methods Patients…
View details →DOI: 10.1016/j.jacep.2025.12.037 Negative / Null Result ReportMedicine
McHugh EG, Marudo C, Safvati N et al. · 2026 · The Journal of perinatal education
The postpartum period is pivotal for both maternal and infant well-being, yet factors influencing postpartum readiness remain underexplored. This study investigates these factors with an emphasis on the impact of perinatal educators on…
View details →DOI: 10.1891/jpe-2024-0031 Negative / Null Result ReportMedicine
Li X, Wei X, Liu H · 2026 · Acta psychologica
The detrimental effect of demotivation on language learning engagement and achievement highlights the necessity to explore its antecedents. This research specifically delves into the intricate interplay between demotivation, self-esteem,…
View details →DOI: 10.1016/j.actpsy.2026.106964 Negative / Null Result ReportMedicine
Chen X, An Z, Li C et al. · 2026 · Clinical and experimental medicine
Anti-citrullinated peptide/protein antibodies (ACPAs) are specific serological markers for rheumatoid arthritis (RA), but their direct role in promoting osteoclastogenesis remains controversial. This study aims to determine whether…
View details →DOI: 10.1007/s10238-026-02208-1 Negative / Null Result ReportMedicine
Masood M, Lane B, Maghfour J et al. · 2026 · Clinical and experimental dermatology
Post-inflammatory hyperpigmentation (PIH) is a common complication following trauma or cutaneous inflammation, particularly affecting individuals with skin of colour. Tranexamic acid (TXA) is a lysine analogue with antifibrinolytic…
View details →DOI: 10.1093/ced/llag082 Negative / Null Result ReportMedicine
Banjoko A, Harris N, Mousavi S et al. · 2026 · Journal of clinical medicine
Background/Objectives: Shift work is a form of circadian dysregulation, which has been associated with adverse reproductive health outcomes. However, the association between circadian dysregulation and ovarian reserve remains uncertain.…
View details →DOI: 10.3390/jcm15124769 Negative / Null Result ReportMedicine
Zhao Y, Peng Z, Cao D et al. · 2026 · BMC health services research
Background The Chinese government piloted the public hospital's compensation system reform in 2017. It is important for policymakers to understand how this reform has affected the health workforce's compensation and its structure. We…
View details →DOI: 10.1186/s12913-026-14850-2 Negative / Null Result ReportMedicine
Zazzeron L, Grancini V, Trombetta M et al. · 2026 · Frontiers in endocrinology
Background Cystic fibrosis-related diabetes (CFRD) is the most common extra-pulmonary complication in adults with cystic fibrosis (CF) and is primarily driven by progressive beta-cell dysfunction. The impact of CFTR modulators,…
View details →DOI: 10.3389/fendo.2026.1774728 Negative / Null Result Report
Bayoglu B, Akdeniz G, Kocabasoglu N et al. · 2026 · Preprint
Abstract Background: Neuronal growth regulator 1 (NEGR1) is a cell adhesion molecule involved in neuronal development and has been identified as a genetic risk locus for major depressive disorder (MDD). However, its functional role and…
View details →DOI: 10.21203/rs.3.rs-4421084/v3 Negative / Null Result ReportMedicine
Tapescu I, Brody RM, Cao AC et al. · 2026 · Oral oncology
Objectives To determine the incidence of pathologic retropharyngeal lymph node (RPLN) metastases, evaluate the accuracy of preoperative imaging, identify predictors for RPLN involvement, and assess the impact of pathologic RPLN metastases…
View details →DOI: 10.1016/j.oraloncology.2026.108056 Negative / Null Result ReportMedicine
Prasad D, Feltham G, De Giorgi R et al. · 2026 · Journal of psychopharmacology (Oxford, England)
Introduction Cognitive flexibility, defined as the ability to shift mental strategies when environmental demands change, may influence psychological well-being and psychiatric treatment outcomes. Research increasingly implicates the renin…
View details →DOI: 10.1177/02698811261456198 Negative / Null Result ReportMedicine
Miño V, Bacigalupo F, Quezada-Scholz VE et al. · 2026 · Acta psychologica
The present study investigated whether cognitive reappraisal modulates conditioned responding during extinction in a socially relevant fear-conditioning paradigm and whether these effects vary as a function of 5-HTTLPR genotype and…
View details →DOI: 10.1016/j.actpsy.2026.107326 Negative / Null Result ReportMedicine
Gajula SNR, Kallam JS, Kanukolanu A et al. · 2026 · Biopharmaceutics & drug disposition
Echinacea is a widely used herbal supplement and is frequently co-administered with antiviral drugs, raising concerns regarding potential herb-drug interactions. This study evaluated the effect of repeated Echinacea administration on the…
View details →DOI: 10.1002/bdd.70034 Negative / Null Result ReportMedicine
Zhang P, Iskandarani ME, Riggs S · 2026 · IEEE transactions on visualization and computer graphics
Optical see-through head-mounted displays (OST-HMDs) allow users to interact with both physical and virtual displays overlaid in the real world within augmented reality (AR) environments. When arranging these displays in space, spatial…
View details →DOI: 10.1109/tvcg.2026.3679118 Negative / Null Result ReportMedicine
Ahmed ME, Mahjoub SMAH, Adam SIY · 2026 · Tropical animal health and production
This study evaluated the effects of partially replacing groundnut cake with soaked chickpea (Cicer arietinum L.) seeds, with or without enzyme supplementation, on growth performance, carcass traits, serum biochemical indices, and…
View details →DOI: 10.1007/s11250-026-05146-y Negative / Null Result Report
Ren X, Wu Q, Zhao M et al. · 2026 · Preprint
This research aimed to determine the effects of replacing ryegrass (Lolium perenne L.) with licorice residue (LR) on growth performance, slaughtering performance, meat quality, serum biochemistry and cecal flora. Five pelleted rations were…
View details →DOI: 10.20944/preprints202605.1776.v1 Negative / Null Result Report
Uğurlu T, Sağlam BC, Koçak S et al. · 2026 · Preprint
Abstract Background The aim of this in vitro study was to examine the effects of different glide path files on root canal transportation and centering in curved root canals. Methods In this study, 33 mandibular first molars with a 10 mm…
View details →DOI: 10.21203/rs.3.rs-9516903/v1 Negative / Null Result Report
Alqantash AH, Alshehri SM, Almalki AA et al. · 2026 · Preprint
Abstract Background Medical students, as future healthcare providers, must possess a comprehensive understanding of medication safety during pregnancy to prevent teratogenic risks and ensure maternal health. Knowledge gaps in this area can…
View details →DOI: 10.21203/rs.3.rs-9666557/v1 Negative / Null Result ReportMedicine
Thapa K, R Iyer A, A Cruz-Gonzalez M et al. · 2026 · Journal of racial and ethnic health disparities
Background Refugees often experience disruptions in social networks after resettlement. This study examined associations between bonding (within-group) and bridging (across-group) social capital and self-rated health among resettled U.S.…
View details →DOI: 10.1007/s40615-026-03052-5 Negative / Null Result Report
Kozakoğlu F, Gürses M · 2026 · Preprint
Abstract Objectives: This study aimed to evaluate the 1-year clinical performance of Ribbond-reinforced direct composite restorations placed in different orientations in endodontically treated posterior teeth. Materials and Methods: This…
View details →DOI: 10.21203/rs.3.rs-9242123/v1 Negative / Null Result ReportMedicine
Mathiesen KK, Rasmussen JH, Channir H et al. · 2026 · Acta oto-laryngologica
Background Cancer of unknown primary (CUP) is diagnostically challenging. Diagnostic strategy remains controversial. Aim The aim of this retrospective study was to evaluate the diagnostic value of FDG-PET/CT and MRI in detecting primary…
View details →DOI: 10.1080/00016489.2025.2612018 Negative / Null Result Report
Vega MM, Roberts MD, Goble DJ et al. · 2026 · Preprint
Abstract Background Aging is associated with increases in fat mass (FM) and decreases in fat-free mass (FFM), yet whether these indices independently predict force plate-derived postural sway and low-frequency postural oscillations remains…
View details →DOI: 10.21203/rs.3.rs-9763487/v1 Negative / Null Result ReportMedicine
Abdulameer HS, Zarrinkavyani K, Fathi M et al. · 2026 · Poultry science
Transport of day-old chicks is a major concern in the poultry industry, as it induces stress that can impair performance and health. This study investigated whether xylazine, an alpha-2 adrenergic agonist that reduces metabolic rate, could…
View details →DOI: 10.1016/j.psj.2026.107191