Failed Experiment ReportMedicine
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of dairy science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
View details →DOI: 10.3168/jds.2025-26959 Abandoned HypothesisOpen accessMedicine
Bybee SG, Clayton JL, Aruscavage N et al. · 2025 · The Gerontologist
Background and objectives Persons living with dementia often rely upon a care partner as their surrogate medical decision maker, yet little is known about how dementia care dyads achieve advance care planning (ACP) concordance: when a care…
View details →DOI: 10.1093/geront/gnaf179 Negative / Null Result ReportMedicine
Achilles S, Tomczak JN, Baumann FS et al. · 2025 · American journal of physiology. Gastrointestinal and liver physiology
DRA (Downregulated in adenoma, SLC26A3) is a major apical intestinal Cl - /HCO 3 - exchanger, which is expressed in complex and hybrid N -glycosylated forms. Although the importance of N -glycosylation is evident from the significantly…
View details →DOI: 10.1152/ajpgi.00362.2024 Negative / Null Result ReportMedicine
Kostrna J, Astudillo A, Perez E · 2025 · Research quarterly for exercise and sport
Extensive research supports the positive effects of stretching on joint flexibility. During stretching, an individual's perceptions of stretch-related discomfort and pain negatively influence affective response. This study examined the…
View details →DOI: 10.1080/02701367.2025.2496765 Negative / Null Result ReportOpen accessMedicine
Tian P, Fan M, Huang C · 2026 · Frontiers in medicine
Background Piperacillin-tazobactam is a widely used antibiotic. Although rare, thrombocytopenia related to piperacillin-tazobactam can be clinically significant. Drug-induced immune thrombocytopenia (DIIT) is difficult to distinguish from…
View details →DOI: 10.3389/fmed.2026.1775491 Negative / Null Result ReportMedicine
Erdoğan Ş, Tavat BC · 2025 · Physiology & behavior
Previous studies have suggested that time perception fluctuates throughout the day in relation to daily fluctuations of body temperature, and that there is a negative relationship between body temperature and time perception. The aim of…
View details →DOI: 10.1016/j.physbeh.2025.114943 Negative / Null Result Report
Necker-Brown A, Mostafa MM, Georgescu A et al. · 2025 · Preprint
Transcription factors of the interferon regulatory factor (IRF) family play key roles during viral and bacterial infections. However, IRF regulation by inflammatory cytokines, including interleukin (IL)-1β and tumor necrosis factor (TNF)…
View details →DOI: 10.1101/2025.07.24.665057 Negative / Null Result ReportMedicine
Yin CY, Vilai P, Thoreson AR et al. · 2026 · The Journal of hand surgery
Purpose Radial lengthening has been clinically proposed as an alternative treatment for distal radioulnar joint (DRUJ) instability associated with distal radius fractures based on the hypothesis that it functions in a manner similar to…
View details →DOI: 10.1016/j.jhsa.2025.06.013 Negative / Null Result Report
O’Brien C, Simon O, Franklin S et al. · 2025 · Preprint
Background: : Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives: : Comparison of physiological effects and behavioural…
View details →DOI: 10.22541/au.174653952.22621289/v1 Negative / Null Result ReportMedicine
Cinque K, Deere D, Veal C et al. · 2025 · Environmental management
The major drinking water reservoirs and catchments supplying many of Australia's capital cities have been protected from significant levels of public access since their construction (up to 140 years ago). In addition to the primary…
View details →DOI: 10.1007/s00267-025-02203-4 Negative / Null Result ReportMedicine
Xiong GL, Iosif AM, Gonzalez AD et al. · 2025 · Journal of the American Medical Directors Association
Objective Comparison of asynchronous telepsychiatry (ATP) with traditional synchronous telepsychiatry (STP) in skilled nursing facilities (SNFs) in California, United States. Design Patient-level randomized, controlled noninferiority…
View details →DOI: 10.1016/j.jamda.2025.105753 Negative / Null Result ReportMedicine
Karst J, Miller M, Simpson P et al. · 2026 · Journal of child health care : for professionals working with children in the hospital and community
Sickle Cell Disease (SCD) is associated with neurocognitive impairment, and routine cognitive and academic screening is recommended. Traditional reports following testing are often not health literate, limiting the usefulness of…
View details →DOI: 10.1177/13674935251326787 Negative / Null Result ReportMedicine
Bai X, Zhou D, Luo J et al. · 2025 · Medicine
Lipid metabolism abnormalities and inflammation have been implicated in gallstone disease (GSD) development, but the causal relationships and potential mediation effects among lipid metabolites, inflammatory factors, and GSD remain…
View details →DOI: 10.1097/md.0000000000044704 Negative / Null Result ReportMedicine
Ibáñez-Álamo JD, Delhey K, Izquierdo L et al. · 2025 · Ecology letters
Rapidly expanding urbanisation presents significant challenges to wildlife. Consequently, many studies have investigated the impact of urbanisation on diverse organisms. However, despite the ecological relevance of animal colouration, its…
View details →DOI: 10.1111/ele.70106 Negative / Null Result ReportOpen accessMedicine
Lee JS, Kim E, Lee UJ et al. · 2026 · Journal of Cancer
Background : The intake of red or processed meat remains controversial as a crucial factor for CRC. Thus, we performed in-depth biological monitoring. Methods: We performed a case- control study and analyzed various exposure and response…
View details →DOI: 10.7150/jca.126466 Negative / Null Result ReportOpen accessMedicine
Vural NA, Mergen B, Güler S et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : To evaluate ocular findings in women with cervical HPV positivity undergoing loop electrosurgical excision procedure (LEEP) for cervical dysplasia and to assess conjunctival/eyelid papilloma and other ocular…
View details →DOI: 10.3390/medicina62050969 Negative / Null Result ReportMedicine
Daniel F, El Kouzi Z, Mrad J et al. · 2025 · Updates in surgery
Preoperative use of biologics has been inconsistently reported to be associated with increased frequency of infectious and surgical anastomotic complications in inflammatory bowel disease patients. We aimed to evaluate the rates of 30-day…
View details →DOI: 10.1007/s13304-025-02238-6 Negative / Null Result ReportMedicine
Albulescu P, Macsinga I, Sulea C et al. · 2025 · Psychological reports
In contemporary, high-speed work settings, ensuring the well-being of employees is of paramount importance. The current study builds on this concern about employee well-being and aims to explore the complex connection between workload (as…
View details →DOI: 10.1177/00332941251317632 Negative / Null Result ReportMedicine
Gückel T, Prior K, Newton NC et al. · 2025 · Behaviour research and therapy
Background Research has documented the prevalence and treatment of co-occurring anxiety and alcohol use, but the mechanisms underlying treatment efficacy, especially in online interventions, remain unclear. This study investigated the…
View details →DOI: 10.1016/j.brat.2025.104766 Negative / Null Result ReportMedicine
Serin I, Unal A, Dobral A et al. · 2025 · High altitude medicine & biology
Serin, Istemi, Ahmet Unal, Arzu Dobral, Fatma Elif Eroglu, Erdem Ayik, Jale Oz Unal, Mehmet Barış Cengiz, Okan Kati, Toros Taskin, Vural Bastug, and Abdulkadir Karismaz. The Effect of altitude on polycythemia vera: Is it necessary to…
View details →DOI: 10.1089/ham.2025.0001 Negative / Null Result ReportOpen accessMedicine
Zhou Z, Huang L, Sheng L et al. · 2026 · Frontiers in cell and developmental biology
Background Immune dysregulation is implicated in pregnancy complications, particularly gestational diabetes mellitus (GDM). This study aimed to identify immune-related genes and characterize immune cell infiltration in GDM placentas.…
View details →DOI: 10.3389/fcell.2026.1803128 Negative / Null Result ReportOpen accessMedicine
Büyükdemirtaş B, Benn M, Kwon HB et al. · 2026 · Psychopharmacology
Rationale Binge drinking during adolescence is associated with a higher risk of developing Alcohol Use Disorders and impaired stress reactivity in adulthood. The hypothalamic-pituitary-adrenal axis matures during adolescence and is under…
View details →DOI: 10.1007/s00213-025-06969-7 Negative / Null Result ReportMedicine
Isaacson BN, Serbin SP, Grabosky JC · 2025 · Forest Ecology and Management.
There is a vigorous debate around whether and how to manage forests for climate mitigation or for other goals such as biodiversity. To achieve any of these goals it is necessary to define the parameters within which they can exist;…
Negative / Null Result ReportOpen accessMedicine
Kanyorszky ET, Sterczer Á, Vizi Z et al. · 2026 · BMC veterinary research
BACKGROUND: Acute pancreatitis triggers the production of acute-phase proteins (APPs) in the body, among which C-reactive protein (CRP) is the most extensively studied and widely used for both diagnosis and prognosis. The diagnostic value…
View details →DOI: 10.1186/s12917-026-05409-8 Negative / Null Result Report
Ghamgosar Shahkhali M, Liu L, Ghamgosar Shahkhali MH et al. · 2025 · Preprint
Objective To explore potential genetic and/or causal associations between Post-Traumatic Stress Disorder and neurodegeneration-related isolated/idiopathic rapid-eye-movement sleep behavior disorder. Methods We conducted polygenic risk…
View details →DOI: 10.1101/2025.09.05.25335205 Negative / Null Result ReportMedicine
Yang T, Yuan X, Gao W et al. · 2024 · Internal and emergency medicine
Observational studies revealed paradoxically inverse associations between diabetes and aortic diseases (aortic aneurysm or aortic dissection), yet the causality remains to be determined. To investigate the causal associations between…
View details →DOI: 10.1007/s11739-024-03727-z Negative / Null Result ReportOpen accessMedicine
Zhang H, Zhao T, Zheng H et al. · 2026 · BMC neurology
Neuronal intranuclear inclusion disease (NIID) is a rare, progressive neurodegenerative disorder caused by abnormal GGC repeat expansions in the NOTCH2NLC gene, leading to multisystem involvement. Electrophysiological abnormalities in NIID…
View details →DOI: 10.1186/s12883-026-04898-2 Negative / Null Result ReportMedicine
Berger M, Bruggisser F, Schwarz A et al. · 2025 · Physiology & behavior
Objectives To investigate whether a single session of aerobic exercise improves inhibitory control in preadolescent children and whether this effect is mediated by changes in parasympathetic activity. Design In this experimental study, an…
View details →DOI: 10.1016/j.physbeh.2025.114820 Failed Experiment ReportMedicine
Martinez G, Tolentino K, Sukheja P et al. · 2025 · Bioorganic & medicinal chemistry letters
Screening of the ChemDiv molecular library in cholesterol media against Mycobacterium tuberculosis (Mtb) H37Rv strain identified a novel isoxazole thiophene hit as a putative Rv1625c/Cya activator with a promising in vitro activity and…
View details →DOI: 10.1016/j.bmcl.2025.130108 Negative / Null Result Report
Su Z, Wyble B, Fu Y · 2024 · Preprint
This study explores the relationship between working memory and attention during visual search tasks, focusing on how time constraints affect the encoding of visual information into working memory. The research is based on the premise that…
View details →DOI: 10.31234/osf.io/d4hc5 