Negative / Null Result ReportOpen accessMedicine
Takemura K, Murakawa Y, Kono H et al. · 2026 · Case reports in oncology
Introduction Fruquintinib is a selective vascular endothelial growth factor receptor inhibitor approved for metastatic colorectal cancer (mCRC) that is refractory to standard therapies. While its efficacy and safety have been demonstrated…
View details →DOI: 10.1159/000549871 Negative / Null Result ReportMedicine
Yılmaz NA, Caner İ · 2026 · BMC medical education
Innovative educational strategies are increasingly needed in physiotherapy education to support students' learning and professional development. Game-based learning (GBL) is an interactive, student-centered approach that may enhance…
View details →DOI: 10.1186/s12909-026-09782-8 Negative / Null Result ReportMedicine
Schwab ME, Stottlemyre R, Khan FA · 2026 · Journal of pediatric surgery
Purpose In patients with congenital lung malformations (CLM), prenatal imaging is used to risk stratify patients and delineate algorithms for delivery planning and neonatal care. Most algorithms include a chest x-ray immediately after…
View details →DOI: 10.1016/j.jpedsurg.2026.163261 Negative / Null Result Report
Spitz J, Langlotz A, Lunow J et al. · 2026 · Preprint
1. How changes in habitat conditions influence insect diversity has been intensively studied. However, whether trophic interactions of insects are also influenced by such changes is largely unknown. Higher habitat heterogeneity is often…
View details →DOI: 10.32942/x2wx00 Negative / Null Result ReportOpen accessMedicine
Ziraldo ER, Yang Y, Arcand J et al. · 2026 · Public health nutrition
Objectives To assess changes in (1) Na content of processed foods in the Canadian food supply and (2) the proportion of products meeting Health Canada's voluntary Na reduction targets (SRT) between 2010 and 2020. Design This repeated,…
View details →DOI: 10.1017/s1368980026102067 Negative / Null Result Report
bai j, han m, wu x et al. · 2026 · Preprint
Abstract Background It is reported that the micro-functional connections of obese patients are abnormal and vary greatly after bariatric surgery. However the effect and change of the overall brain functional connection remain uncertain.…
View details →DOI: 10.21203/rs.3.rs-8318590/v1 Negative / Null Result ReportMedicine
Yin R, Qin Y, Liang X et al. · 2026 · International journal of molecular sciences
Fungal iterative non-reducing polyketide synthases (NR-PKS) contain a unique product template (PT) domain for aromatic cyclization. Among them, some NR-PKSs, such as the sorbicillin NR-PKS (SorB), have an apparently inactive PT. It is…
View details →DOI: 10.3390/ijms27125534 Negative / Null Result ReportMedicine
Ling SHT, Zafiris E, Cohen JN et al. · 2026 · Journal of applied physiology (Bethesda, Md. : 1985)
Conventional duplex ultrasound is commonly used to measure blood velocity in the internal carotid artery (ICA) for disease screening and cerebral or extracranial flow estimation. Pouseillian-based flow calculations assume laminar flow,…
View details →DOI: 10.1152/japplphysiol.00452.2026 Negative / Null Result ReportMedicine
Lee S, Lee M, Song H et al. · 2026 · Addictive behaviors
Ecological momentary assessment (EMA) may function not only as an assessment method but possibly also an intervention strategy by increasing self-monitoring and awareness of drinking behavior. Personalized feedback (PF) integrated with EMA…
View details →DOI: 10.1016/j.addbeh.2026.108780 Negative / Null Result ReportMedicine
Sadighi T, Dudley A, Churaman B et al. · 2026 · Nursing education perspectives
This study explored the impact of an interprofessional mass casualty simulation on undergraduate nursing students' disaster preparedness. A total of 127 students participated; 50 completed pre- and postsurveys using a validated 14-item…
View details →DOI: 10.1097/01.nep.0000000000001542 Negative / Null Result ReportMedicine
Skotniczny K, Terbalyan A, Linek P et al. · 2026 · Nutrients
Background Acute dehydration impairs performance, but its effects on resting neuromuscular and tissue mechanics are unclear. We tested whether baseline hydration status and exercise-induced sweat loss alter the resting neuromechanical…
View details →DOI: 10.3390/nu18122015 Negative / Null Result ReportMedicine
Xiao J, Choi HM, Yim G et al. · 2026 · American journal of epidemiology
Epidemiological evidence on whether cesarean delivery influences offspring neurodevelopment remains inconsistent. We evaluated the associations between maternal cesarean delivery and childhood autism spectrum disorder (ASD) and…
View details →DOI: 10.1093/aje/kwag150 Negative / Null Result Report
Mevliyaoğulları E · 2026 · Preprint
Abstract Background The present study evaluated a technology-driven approach for producing a plant-protein-rich bird food based on colloid-mill-modified zein suspension and compared its first-clutch reproductive performance with an…
View details →DOI: 10.21203/rs.3.rs-9904294/v1 Negative / Null Result ReportMedicine
Bilici N, Paruzel-Czachura M, Workman CI et al. · 2026 · BMC psychology
Facial anomalies, such as scars, are often linked to an "anomalous-is-bad" stereotype, in which people with visible differences are seen as less warm or less moral. We developed the "Normalizing Anomalies with Mobile Exposure" (NAME)…
View details →DOI: 10.1186/s40359-026-04964-x Negative / Null Result ReportMedicine
Akimoto Y, Itagaki T, Takashima T et al. · 2026 · Respiratory care
Background High-flow nasal cannula (HFNC) is commonly used for acute hypoxemic respiratory failure and for subjects at risk of postextubation failure. HFNC reduces inspiratory work, but its effects on expiratory muscle activity, including…
View details →DOI: 10.1177/19433654261453032 Negative / Null Result ReportMedicine
Tschoner T, Mueller KR, Zablotski Y et al. · 2026 · The Veterinary record
Background Cattle only show subtle signs of pain, making pain assessment difficult. The approach to pain and the use of analgesics depend on the treating person's experience and opinions. Methods Bavarian veterinary students were asked to…
View details →DOI: 10.1002/vetr.70731 Negative / Null Result ReportMedicine
Fiszdon JM, Wang K, Fulford D et al. · 2026 · Journal of the International Neuropsychological Society : JINS
Objectives Poor social function in people with psychosis has been linked to impairments in social cognition and neurocognition, which in turn have been identified as promising treatment targets. We developed a novel social cognitive…
View details →DOI: 10.1017/s1355617726102070 Negative / Null Result ReportMedicine
Liu N, Zhao J, Wu B et al. · 2026 · International ophthalmology
Purpose To evaluate the changes in corneal astigmatism, axial length and anterior chamber depth following vitrectomy versus phacovitrectomy in patients with rhegmatogenous retinal detachment (RRD) under more detail group.To discuss how to…
View details →DOI: 10.1007/s10792-026-04139-y Negative / Null Result ReportMedicine
Mitzner TL, Remillard ET, Mumma KT et al. · 2026 · Healthcare (Basel, Switzerland)
Background/Objectives : Telewellness programs can expand access to exercise and social opportunities for older adults, especially those with mobility disabilities. The TechSAge Tele Tai Chi clinical trial assessed whether the Tai Chi for…
View details →DOI: 10.3390/healthcare14121756 Negative / Null Result ReportMedicine
Terao R, Yashiro K, Kuriyama T et al. · 2026 · BMC ophthalmology
Background This study is aimed to evaluate retinal pigment epithelium (RPE) entropy in eyes with full-thickness macular hole (FTMH) using polarization-sensitive optical coherence tomography (PS-OCT). Methods Patients diagnosed with…
View details →DOI: 10.1186/s12886-026-05008-z Negative / Null Result ReportMedicine
Kerr S, Minatoguchi S, Dumitriu Carcoana AO et al. · 2026 · Cardiovascular intervention and therapeutics
This study evaluated the serial anatomical and morphological changes in de novo coronary lesions treated with a drug-coated balloon (DCB) using integrated-backscatter intravascular ultrasound (IB-IVUS). The aim of this study was to…
View details →DOI: 10.1007/s12928-026-01298-8 Negative / Null Result ReportMedicine
Kotenko O, Kozlovskaya N, Emirova K et al. · 2026 · Nephron
Background The objective of a multicentre, prospective, observational study of an eculizumab biosimilar (Elizaria®) was to analyse the efficacy and safety of long-term complement inhibitor therapy in patients with atypical haemolytic…
View details →DOI: 10.1159/000552914 Negative / Null Result Report
Tao J, Cheng D, Wang N · 2026 · Preprint
Abstract Background Fluid retention and the obesity paradox often mask true muscle wasting in patients with proteinuric chronic kidney disease (CKD), and conventional quantity-based metrics such as body mass index or cross-sectional tissue…
View details →DOI: 10.21203/rs.3.rs-9335582/v1 Negative / Null Result ReportMedicine
Joswig H, Oreizi-Esfahani S, Medack S et al. · 2026 · World neurosurgery
Background Parkinson's disease (PD) is a neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra, resulting in motor and nonmotor symptoms including diminished sleep quality and altered dream…
View details →DOI: 10.1016/j.wneu.2026.124816 Negative / Null Result ReportOpen accessMedicine
Raza GS, Jokelainen J, Stenbäck V et al. · 2026 · PloS one
Physical activity (PA) has numerous positive health effects, including improvements in cognitive function. PA stimulates the release of glycosylphosphatidylinositol-specific phospholipase D1 (GPLD1) from the liver, resulting in hippocampal…
View details →DOI: 10.1371/journal.pone.0349883 Negative / Null Result ReportMedicine
Esen Öksüzoğlu M, Kabukçu HO · 2026 · BMC psychiatry
Background Sleep terror (ST) is a common NREM parasomnia in early childhood and may be associated with broader emotional and behavioral dysregulation. However, its links with psychopathological symptoms and nutritional biomarkers remain…
View details →DOI: 10.1186/s12888-026-08298-1 Negative / Null Result Report
Agarwal P, Thapa M, Karki P · 2026 · Preprint
Abstract Background Increase in IOP after Vitreoretinal surgery is uncommon but sight threatening complication. This study aims to determine the incidence and risk factors of intraocular pressure (IOP) elevation following vitreoretinal…
View details →DOI: 10.21203/rs.3.rs-9509509/v1 Negative / Null Result ReportMedicine
Tcherner S, Durom E, Peters J et al. · 2026 · COPD
In patients with moderate-to-severe COPD, airway mucus-occlusions correlate with airflow limitation, exacerbation and mortality-risk. However, the clinical relevance of mucus-plugs in milder COPD is not well-understood. We evaluated…
View details →DOI: 10.1080/15412555.2026.2681969 Negative / Null Result ReportMedicine
Huang F, Chen K · 2026 · Human factors
ObjectiveThis study investigated how affective characteristics of interruptions (valence and arousal) influence task resumptions and post-interruption performance in younger and middle-aged/older adults under different task…
View details →DOI: 10.1177/00187208261446106 Negative / Null Result Report
Sevahil D · 2026 · Preprint
The aim of this study was to examine the causal pathways from prosocial behavior to well-being in different grades of primary school children. We assessed for whether family support andpeer acceptance mediate this relationship, along to…
View details →DOI: 10.31234/osf.io/nyahz_v1