Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Jianfeng Li, Hongjie Zhu, Nanzhi Luo et al. · 2024 · Discover Oncology
Abstract The optimal surgical approach for elderly patients with early-stage non-small cell lung cancer (NSCLC) remains a topic of debate. A retrospective analysis was conducted on patients who underwent pulmonary resection for early-stage NSCLC at our single institution between January 2018 and December 2022. Propensity score matching was used to balance baseline characteristics between the sublobar resection and lobectomy groups. Perioperative outcomes, pulmonary function recovery, postoperative quality of life, and survival were compared between the two groups. A total of 151 patients were
View details →DOI: 10.1007/s12672-024-01468-1 Negative / Null Result ReportOpen accessForestry
Michael M. Müller, Leena Hamberg, Martti Varama · 2023 · Silva Fennica
Unequivocal evidence on the antagonistic effects of endophytic fungi associated with woody plants against insect herbivores has been documented in only a few cases so far. Experimental evidence of the significance of needle endophytes to coniferous trees has remained scant because it is difficult to obtain trees with needles free of endophytes that could be used as comparable controls for trees infected with endophytes. Previously we reported a new methodology to get Norway spruce (Picea abies (L.) Karst.) saplings without needle endophytes and to inoculate them with a needle endophyte Lophode
View details →DOI: 10.14214/sf.23026 Negative / Null Result ReportOpen accessMedicine
Laura Sterian Ward, Ilda Shizue Kunii, Rui Monteiro de Barros Maciel · 2000 · São Paulo Medical Journal
CONTEXT: Screening programs not only offer the opportunity to trace and treat almost all cases of congenital hypothyroidism but also mean large savings to the health system. However, carefully planned strategies are necessary to extend their benefits and reduce costs. OBJECTIVE: To determine the possible influence of maternal diseases that affect maternal-fetal placenta dynamics on primary thyroid stimulating hormone (TSH) screening for congenital hypothyroidism. DESIGN: Prospective non-randomized clinical trial with at least 3 months of follow-up. SETTING: A public university referral center
View details →DOI: 10.1590/s1516-31802000000500006 Negative / Null Result ReportOpen accessMedicine
Magdalena Dudek, Marta Kałużna-Oleksy, Jacek Migaj et al. · 2018 · Journal of Medical Science
Background. Coronary artery disease (CAD) is one of the most important causes of death in both men and women. There are many gender differences among patients with CAD, including risk factors and acute coronary syndrome (ACS) outcomes. The latest reports showed that mortality due to CAD is higher in women than in men. Cardiac biomarkers play an important role in risk stratification and choice of treatment strategy in patients with ACS, however some of cardiac biomarkers show worse sensitivity and specificity in women. Aim. The aim was to investigate the sex-related differences in patients with
View details →DOI: 10.20883/jms.2018.268 Negative / Null Result ReportOpen accessSurgery
Christiane Simioni, Edward Araujo Júnior, Wellington P. Martins et al. · 2012 · Brazilian Journal of Cardiovascular Surgery
OBJETIVO: Comparar do débito cardíaco (DC) e a fração de ejeção (FE) do coração de fetos masculinos e femininos obtidos por meio da ultrassonografia tridimensional, utilizando o spatio-temporal image correlation (STIC). MÉTODOS: Realizou-se um estudo de corte transversal com 216 fetos normais, entre 20 a 34 semanas de gestação, sendo 108 masculinos e 108 femininos. Os volumes ventriculares no final da sístole e diástole foram obtidos por meio do STIC, sendo as avaliações volumétricas realizadas pelo virtual organ computer-aided analysis (VOCAL) com rotação de 30º. Para o cálculo do DC utilizou
View details →DOI: 10.5935/1678-9741.20120058 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Sahil Kumar, Elise Bertin, Cormac O'Dwyer et al. · 2023 · Asian Journal of Andrology
Transmasculine individuals, considering whether to undergo total hysterectomy with bilateral salpingectomy, have the option to have a concomitant oophorectomy. While studies have evaluated hormone changes following testosterone therapy initiation, most of those patients have not undergone oophorectomy. Data are currently limited to support health outcomes regarding the decision to retain or remove the ovaries. We performed a retrospective chart review of transmasculine patients maintained on high-dose testosterone therapy at a single endocrine clinic in Vancouver, British Columbia, Canada. Twe
View details →DOI: 10.4103/aja202262 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Ahmed Alnajar, MD, MSPH, Subhasis Chatterjee, MD, Jacqueline K. Olive, MD et al. · 2024 · JTCVS Open
Objective: Isolated tricuspid valve surgery is uncommon and associated with high perioperative morbidity and mortality. We aimed to study the overall outcomes of patients who underwent minimally invasive right thoracotomy tricuspid valve surgery (Mini-TVS), consisting of either tricuspid valve repair (TVre) or replacement (TVR). Methods: We performed a retrospective analysis of all Mini-TVS procedures (2017-2022), through which we identified isolated tricuspid valve surgeries. We examined in-hospital outcomes, survival analysis over a 4-year period, and competing risk analysis for reoperative
View details →DOI: 10.1016/j.xjon.2023.12.009 Negative / Null Result ReportOpen accessSurgery
Ali Andalib · 2016 · Global Spine Journal
Introduction Although Adolescent Idiopathic Scoliosis patients have lower Bone Mineral Density (BMD) but relationship between BMD and curve pattern, intensity of curve, or its progress in these patients is controversial. Some studies have shown a significant difference between left and right proximal femur BMDs in AIS patients. Since the curve pattern relationship with density of bilateral proximal femur has not been identified, this study aims to investigate the relationship between Spinal Coronal Profile and differences in BMD on either sides of proximal femur in patients with AIS. Material
View details →DOI: 10.1055/s-0036-1582810 Negative / Null Result ReportOpen accessSports
Ülküm Erdoğan Yüce, Özcan Saygın · 2023 · Spor Bilimleri Araştırmaları Dergisi
The aim of the study was to examine the effect of walking football applied to elderly male sedentary individuals on life satisfaction and heart rate variability. 22 male volunteers whose physical activity level was determined by International Physical Activity Questionnaire (IPAQ) were included to this study. Volunteers were divided into 11 exercise groups and 11 control groups by random sampling. While the control group had no activity participation, the exercise group performed a 20-minute warm-up, they played 60 minutes of walking football, and they performed a 10-minute cool down. This was
View details →DOI: 10.25307/jssr.1271937 Negative / Null Result ReportOpen accessMedicine
Chia Hassan Ali, Rozhan Yassin Khalil · 2025 · Advanced Medical Journal
Background and objectives: Various methods and devices are currently applicable to diagnose endometrial polyps with different outcomes. This study aimed to compare the efficacy of trans-vaginal ultra-sonography in relation to the rigid hysteroscopy in the diagnosis of endometrial polyps in patients with abnormal vaginal bleeding. Methods: This cross-sectional study enrolled 70 female patients with endometrial polyps at Sulaimani Maternity Teaching Hospital, Iraq, from May 01, 2022 to May 01, 2023. A well-designed questionnaire including the patient's age, gender, residency, educational level,
View details →DOI: 10.56056/amj.2025.356 Negative / Null Result ReportOpen accessPhysics
S. Feng, S. Feng, S. Feng et al. · 2016 · Atmospheric Chemistry and Physics
Megacities are major sources of anthropogenic fossil fuel CO 2 (FFCO 2 ) emissions. The spatial extents of these large urban systems cover areas of 10 000 km 2 or more with complex topography and changing landscapes. We present a high-resolution land–atmosphere modelling system for urban CO 2 emissions over the Los Angeles (LA) megacity area. The Weather Research and Forecasting (WRF)-Chem model was coupled to a very high-resolution FFCO 2 emission product, Hestia-LA, to simulate atmospheric CO 2 concentrations across the LA megacity at spatial resolutions as fine as ∼ 1 km. We evaluated multi
View details →DOI: 10.5194/acp-16-9019-2016 Negative / Null Result ReportOpen accessMedical physics. Medical radiology. Nuclear medicine
Mohamed S. Alwarraky, Mohamed M. Abdallah, Mohamed S. Elgharbawy · 2020 · The Egyptian Journal of Radiology and Nuclear Medicine
Abstract Background To evaluate how far is selective renal artery embolization (RAE) using permanent agents effective in treating acute renal artery bleeding. We retrospectively reviewed the medical records of patients (n = 45) with renal bleeding who were managed by selective RAE using coils, N-butyl-cyanoacrylate glue (NBCA glue), and polyvinyl alcohol (PVA). Data retrieved included the cause, number, and type of the bleeding lesions as well as the results of the embolization for 1 year after RAE. Clinical success was the primary outcome while re-bleeding and complications were the secondary
View details →DOI: 10.1186/s43055-020-00328-6 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Mengyun Li, Qing Zhang, Xu Wang et al. · 2024 · Frontiers in Neurology
ObjectiveThis study aimed to analyze the clinical characteristics and prognosis of patients with autoimmune encephalitis (PWAE) who experienced seizures during the acute phase.MethodsClinical data were collected from 84 patients diagnosed with AE at the General Hospital of Ningxia Medical University between January 2015 and January 2023. Patients were divided into seizure and non-seizure groups. Clinical characteristics of both groups were compared, including differences between anti-NMDAR and anti-LGI1 encephalitis within the seizure group. Due to the limited sample size and to avoid overfitt
View details →DOI: 10.3389/fneur.2024.1474888 Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Eva B. Aamodt, Martin Røvang, Mona K. Beyer et al. · 2026 · Frontiers in Neurology
BackgroundMeasures of white matter hyperintensities (WMHs) represent a crucial part of post-stroke outcome prediction. Automatic WMH segmentation has proven particularly challenging in stroke cases. Using an improved method for WMH segmentation that incorporates stroke lesions, we set out to explore factors associated with higher WMH burden, as well as the association between WMH burden and post-stroke dependency across two different countries that may demonstrate significant variation in radiological presentation.MethodsA total of 384 acute ischemic stroke (AIS) survivors from the Norwegian C
View details →DOI: 10.3389/fneur.2026.1712109 Negative / Null Result ReportOpen accessBusiness
Euis Soliha, H. Sophiyanto Wuryan · 2016 · Jurnal Manajemen Teori dan Terapan
The purpose of this research is to analyze the effect of the message framing on the perceived psychological risk on green environmental issues. Consumers nowadays have become more critical about issues on green consumer due to the increasing levels of consumers’ knowledge. Government and marketers also should perform active movement to increase consumers’ awareness of their environment. Those include giving a message to the consumers. When marketers deliver the message, they need to concern about message framing. Message framing is likely to influence the consumer's perception. Research design
View details →DOI: 10.20473/jmtt.v6i2.2669 Negative / Null Result ReportOpen accessNursing
Geranmayeh M, Rezaeipour A, Haghani H et al. · 2006 · حیات
Background & Aim: The severe pain of labor is the important cause of fear and anxiety in pregnant women. This study has been performed to evaluate effect of education on midwives practice. Methods & Materials: This is a quasi-experimental study. That was done 59 midwives in the labor wards of non-educational of Guilan University of Medical Sciences Hospital. Data gathered by a questioner, which its validity was done by panel of experts and reliability by test-retest. 59 midwives were chosen by quota sampling and participated in a one-day workshop. Pretest and post-test questioner completed bef
Negative / Null Result ReportOpen accessNeurology. Diseases of the nervous system
Akçay ÖVÜNÇ ÖZÖN, Erhan BİLİR · 2015 · Archives of Epilepsy
Objectives:Epileptic seizures diagnosed wth clinical and electroencephalographic (EEG) signs were classified according to ILAE 1981, Lüders, and ILAE 2001 systems in the present study, the aim of which was to compare classification systems by means of preictal and postictal consistency, and to determine deficiencies of the classification systems.Methods:In the present study, 50 patients who had epileptic seizures during monitorization were evaluated by a single observer at the Gazi University Medical Faculty Long-Term Video-EEG Monitorization Unit between March 2003 and September 2004. Seizure
View details →DOI: 10.5505/epilepsi.2015.48569 Negative / Null Result ReportOpen accessPsychology
Anton P. Martinez, Elizabeth Milne, Georgina Rowse et al. · 2025 · Frontiers in Psychology
BackgroundInformation about the self and others is organized in cognitive-affective structures that influence and guide interpersonal behavior. These structures are referred to as relational schemas and are thought to be influenced by early interpersonal experiences with significant others leading to secure or insecure attachment patterns as adults. When insecure, these patterns appear to contribute to paranoid interpretations about the intentions of others by indirect pathways such as negative self-esteem and a bias toward untrustworthiness. Experimental studies employing classical conditioni
View details →DOI: 10.3389/fpsyg.2024.1474562 Negative / Null Result ReportOpen accessConsciousness. Cognition
Alessandro Mazza, Ellen Voorrips, Gethin Hughes et al. · 2025 · Journal of Cognition
Daily, we perform activities in the presence of others (e.g., office work). While it’s well-established that the mere presence of others can influence our performance, it is less clear whether others’ performance, rather than just their presence, influences us. To address this, we replicated Desender et al.’s (2016) study, Is mental effort contagious?, and conducted a second experiment to follow up on our failure to replicate their findings. Desender et al. (2016) used a modified joint Simon task where two participants performed side by side. The manipulated participant completed an easy (most
View details →DOI: 10.5334/joc.456 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Alexander Kuck, Alexander Kuck, Dick F. Stegeman et al. · 2018 · Frontiers in Neuroscience
Trans-spinal direct current stimulation (tsDCS) is an electro-modulatory tool with possible application in the rehabilitation of spinal cord injury. TsDCS generates a small electric field, aiming to induce lasting, functional neuromodulation in the targeted neuronal networks. Earlier studies have shown significant modulatory effects after application of lumbar tsDCS. However, for clinical application, a better understanding of application specific factors is required. Our goal was to investigate the effect of different electrode configurations using lumbar spinal tsDCS on spinal excitability.
View details →DOI: 10.3389/fnins.2018.00151 Negative / Null Result ReportOpen accessPsychology
Aiste Dirzyte, Aidas Perminas, Aiste Skarnulyte et al. · 2024 · European Journal of Mental Health
Introduction: While personality traits and early maladaptive schemas (EMSs) can affect an individual’s behavior and well-being, the links between these constructs are under-researched, especially in non-clinical samples. Aims: Two studies were conducted to address these links, intending to explore their specifics, as previous research evidenced various associations’ models. Methods: In Study 1, the sample consisted of 120 respondents (65.0% females) living in the UK and the USA. In Study 2, the sample consisted of 244 respondents (68.0% females) living in Lithuania. In both studies, most of th
Negative / Null Result ReportOpen accessMedicine
Nicholette D Palmer, Lingyi Lu, Thomas C Register et al. · 2021 · PLoS ONE
Relative to European Americans, African Americans have lower 25-hydroxyvitamin D (25OHD) and vitamin D binding protein (VDBP) concentrations, higher 1,25-dihydroxyvitamin D (1,25(OH)2D3) concentrations and bone mineral density (BMD), and paradoxically reduced burdens of calcified atherosclerotic plaque (subclinical atherosclerosis). To identify genetic factors contributing to vitamin D and BMD measures, association analysis of >14M variants was conducted in a maximum of 697 African American-Diabetes Heart Study participants with type 2 diabetes (T2D). The most significant association signals w
View details →DOI: 10.1371/journal.pone.0251423 Negative / Null Result ReportOpen accessMedicine
Jianxun Fang, Yuze Cao, Jun Ni · 2024 · European Journal of Medical Research
Abstract Background Intracranial aneurysm (IA) accounts for a substantial source of non-traumatic subarachnoid hemorrhage, with inflammation postulated as a potential factor in its pathogenesis. The present study aims at evaluating the association between circulating inflammatory cytokines and risk of IA under a bidirectional two-sample Mendelian randomization (MR) design. Methods For primary analysis, summary statistics of inflammatory regulators was obtained from a genome-wide association study (GWAS) comprising 8293 Finnish participants. Summary data of IA were extracted from a GWAS which c
View details →DOI: 10.1186/s40001-023-01609-2 Negative / Null Result ReportOpen accessMedicine
Franziska Emmerling, Carolien Martijn, Hugo J E M Alberts et al. · 2017 · PLoS ONE
Cognitive effort and self-control are exhausting. Although evidence is ambiguous, behavioural studies have repeatedly suggested that control-demanding tasks seem to deplete a limited cache of self-regulatory resources leading to performance degradations and fatigue. While resource depletion has indirectly been associated with a decline in right prefrontal cortex capacity, its precise neural underpinnings have not yet been revealed. This study consisted of two independent experiments, which set out to investigate the causal role of the right dorsolateral prefrontal cortex (DLPFC) in a classic d
View details →DOI: 10.1371/journal.pone.0174331 Negative / Null Result ReportOpen accessPsychology
Alberto Manzi, Yana Durmysheva, Shannon K. Pinegar et al. · 2019 · Frontiers in Psychology
Recent research by Vohs et al. (2013) garnered media attention after reporting that disordered environments increase creativity. The present research was designed to conceptually replicate and extend this finding by exploring the effect of workspace disorder on creativity. Participants were randomly assigned to work at a neatly organized (Order condition) or a messy desk (Disorder condition), where they completed several paper-and-pencil and computerized tasks, including two validated creativity measures (Abbreviated Torrance Test for Adults; ATTA; Goff and Torrance, 2002; Alternative Uses Tas
View details →DOI: 10.3389/fpsyg.2018.02662 Negative / Null Result ReportOpen accessBiotechnology
Haoyang Zhao, Mengfan Yang, Yujiao Liu et al. · 2025 · npj Microgravity
Abstract Disuse osteoporosis, caused by mechanical unloading, is linked to dysregulated TGFβ and BMP signaling. This study explores their roles and evaluates BMP9 as a potential therapy. A hindlimb unloading (HLU) mouse model was used to assess bone changes and signaling alterations. In vitro, a Rotary Cell Culture System (RCCS) with 3D printing simulated microgravity. BMP9 was overexpressed in bone marrow stromal cells (BMSCs) and osteocytes treated with TGFβ1. HLU mice showed reduced bone density, microstructural integrity, and dysregulated signaling (increased p-Smad2/3, decreased p-Smad1/5
View details →DOI: 10.1038/s41526-025-00510-y Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Daniel Wiswede, Jascha Rüsseler · 2021 · Frontiers in Human Neuroscience
Introduction: The present study was conducted to verify a promising experimental setup which demonstrated an inversed Stroop-effect (much faster responses for incongruent relative to congruent Stroop trials) following a mismatching tone. In the matching condition, which was an almost exact replication of the original study, participants were required to indicate whether word color and word meaning were matching, whereas in the response conflict condition, instruction was the same as in a classical Stroop task and required the participants to respond to the word color. As in the original study,
View details →DOI: 10.3389/fnhum.2021.680885 Negative / Null Result ReportOpen accessMedicine
Cherubino Paolo, Sala Andrea, Casalone Rosario et al. · 2005 · Journal of Translational Medicine
Abstract Background Local myogenesis, neoangiogenesis and homing of progenitor cells from the bone marrow appear to contribute to repair of the infarcted myocardium. Implantation into heart tissues of autologous skeletal myoblasts has been associated with improved contractile function in animal models and in humans with acute myocardial ischemia. Since heart infarction is most prevalent in individuals of over 40 years of age, we tested whether culture methods available in our laboratory were adequate to obtain sufficient numbers of differentiated skeletal myoblasts from muscle biopsy specimens
View details →DOI: 10.1186/1479-5876-3-21 Negative / Null Result ReportOpen accessPsychology
A. Norvilas, Miller J. C. · 2010 · Psichologija
D. Fernandez-Duque ir I. M. Thornton (2000) tariamai atrado, kad asmuo gali užfiksuoti pakitimą ir be sąmonės įsiterpimo. Tačiau šį atradimą gerokai menkina vienas pačių autorių pripažintas metodologinis trūkumas – kontrolinių bandymų nebuvimas. Siekdami tiksliau nustatyti, ar norint pastebėti pakitimą reikia sąmonės tarpininkavimo, ar jo užfiksavimas gali vykti ir be sąmonės įsiterpimo, dar kartą tyrėme, kaip matomame objekte aptinkamas pasikeitimas, tačiau šį kartą tyrėmė dvejopai: vienu atveju be kontrolinių bandymų, kaip ir D. Fernandez-Duque ir I. M. Thorntonas, o kitu atveju atlikome ir
View details →DOI: 10.15388/psichol.2010.0.2574 Negative / Null Result ReportOpen accessInternal medicine
Elisabeth A. Rosenthal, David R. Crosslin, Adam S. Gordon et al. · 2021 · BMC Medical Genomics
Abstract Background Elevated triglycerides (TG) are associated with, and may be causal for, cardiovascular disease (CVD), and co-morbidities such as type II diabetes and metabolic syndrome. Pathogenic variants in APOA5 and APOC3 as well as risk SNVs in other genes [APOE (rs429358, rs7412), APOA1/C3/A4/A5 gene cluster (rs964184), INSR (rs7248104), CETP (rs7205804), GCKR (rs1260326)] have been shown to affect TG levels. Knowledge of genetic causes for elevated TG may lead to early intervention and targeted treatment for CVD. We previously identified linkage and association of a rare, highly cons
View details →DOI: 10.1186/s12920-020-00854-2 