e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 570 of 725

Negative / Null Result ReportOpen accessMedicine

FreeSurfer-Based MRI Volumetry Reveals Thalamic and Hippocampal Atrophy as Significant Correlates of Disability in Multiple Sclerosis.

Juković M, Stošić S, Kostić D et al. · 2026 · Medicina (Kaunas, Lithuania)

Background and Objectives : Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease that progressively leads to brain atrophy and the accumulation of disability over time. In this study, we used FreeSurfer to…

View details →DOI: 10.3390/medicina62050886
Negative / Null Result ReportOpen accessMedicine

Optimizing and Benchmarking Machine Learning and Traditional Synaptic Event Detection Pipelines in Neurophysiology Experiments.

Sevigny JP, Schrank S, Donka RM et al. · 2026 · eNeuro

Synaptic physiology experiments are fundamental to neuroscience research. Consequently, accurate detection of synaptic currents is crucial for conducting high-quality experiments. Traditionally, detecting inhibitory and excitatory…

View details →DOI: 10.1523/eneuro.0410-25.2026
Negative / Null Result ReportOpen accessMedicine

Economic incentives contribute little to reducing agricultural damage from invasive non-native species: evidence from raccoon management in Hokkaido, Japan.

Mameno K, Suzuki T, Yamaguchi S et al. · 2026 · Pest management science

Background An economic incentive scheme is utilized to enhance citizens' support for managing invasive non-native species. However, the effectiveness of the incentive scheme in the outcomes of the management remains unclear. This study…

View details →DOI: 10.1002/ps.70397
Negative / Null Result ReportOpen accessMedicine

The effect of performance-based financing interventions on health worker motivation and job satisfaction: experimental evidence from six national pilots.

Lamba S, Friedman J, Kandpal E · 2025 · Health policy and planning

A long-standing concern suggests that performance-based financing (PBF) may undermine the intrinsic motivation of health workers by heightening extrinsic motivation concerns via the novel introduction of financial incentives. However, the…

View details →DOI: 10.1093/heapol/czaf035
Negative / Null Result ReportOpen accessMedicine

Prospective association between the triglyceride-glucose index and frailty in middle-aged and older adults: insights from a nationwide cohort study.

Hou J, Zhao S, Shi J et al. · 2026 · European journal of medical research

Background Frailty is notably prevalent in individuals aged 50 and older and has been associated with metabolic dysfunction. The triglyceride-glucose (TyG) index is a reliable surrogate marker for insulin resistance. This study aimed to…

View details →DOI: 10.1186/s40001-026-03895-y
Negative / Null Result ReportMedicine

Does perceptual disfluency affect the illusion of causality?

Bona SD, Vicovaro M · 2024 · Quarterly journal of experimental psychology (2006)

When a subjective experience of difficulty is associated with a mental task, people tend to engage in systematic and deliberative reasoning, which can reduce the usage of intuitive and effortless thinking that gives rise to cognitive…

View details →DOI: 10.1177/17470218231220928
Negative / Null Result ReportOpen accessMedicine

No substantial causal effect of genetic liability to viral infections on subacute thyroiditis: A large-scale Mendelian randomization analysis.

Zeng S, Cheng W · 2026 · Medicine

The association between viral infections and subacute thyroiditis (SAT) has been recognized, yet whether a genetic causal relationship exists between them remains unclear. To address this, we conducted a two-sample Mendelian randomization…

View details →DOI: 10.1097/md.0000000000048696
Negative / Null Result ReportOpen accessMedicine

Investigating if changing the wording of a study invitation letter increased recruitment in a project promoting tobacco cessation in a town with high smoking rates.

Schell C, Godinho A, Cunningham JA · 2026 · Substance abuse treatment, prevention, and policy

BACKGROUND: Invitation letters can be the first point of contact between research staff and potential participants and a number of modifiable variables have been studied to improve their effectiveness. The aim of this analysis was to…

View details →DOI: 10.1186/s13011-026-00704-x
Negative / Null Result ReportOpen accessMedicine

Re-evaluating the Role of Partnership-Related Perceptions in Women's Preferences for Men with Masculine Face Shapes.

Dong J, Leger K, Lee AJ et al. · 2024 · Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior

Many researchers have proposed that women perceive men with masculine face shapes to be less suitable as parents and long-term partners than men with feminine face shapes, causing women to find masculine men more attractive for short-term…

View details →DOI: 10.1177/14747049241262712
Negative / Null Result ReportOpen accessMedicine

Is rate-dependent perception affected by linguistic information about the intended syllable rate?

Severijnen GGA, Bosker HR, McQueen JM · 2025 · Psychonomic bulletin & review

Speech is highly variable in rate, challenging the perception of sound contrasts that are dependent on duration. Listeners deal with such variability by perceiving incoming speech relative to the rate in the surrounding context. For…

View details →DOI: 10.3758/s13423-025-02746-x
Negative / Null Result ReportOpen accessMedicine

Changes in Fertility Trends and Women's Fertility Desires in the Wake of the Homicide Surge in Mexico.

Floridi G, Gargiulo M, Aburto JM · 2026 · Population research and policy review

Since 2006, Mexico has experienced a surge in homicides due to national policies and international influences on drug trafficking activities. Although the effects of the so-called "Drug War" have been extensively studied in demography and…

View details →DOI: 10.1007/s11113-026-09999-x
Negative / Null Result ReportOpen accessMedicine

Association between historical lead exposure, population density, and autism prevalence: a county-level ecological study in Norway.

Grossman A · 2026 · Frontiers in neuroscience

Background Autism spectrum disorder (ASD) prevalence has increased markedly across high-income countries, including Norway, yet environmental drivers remain poorly understood. We hypothesized that historical lead exposure may inversely…

View details →DOI: 10.3389/fnins.2026.1729731
Negative / Null Result Report

Collaborative registered replication of Griskevicius et al. (2010): Can pro-environmental behavior be promoted by priming status motivation?

Lazarevic LB, Wagge JR, Buchanan EM et al. · 2023 · Preprint

The present study presents the results of a collaborative registered replication of Griskevicius et al. (2010, Experiment 1). As part of the Collaborative Replication and Education Project, 24 student groups from six countries (N = 3,774)…

View details →DOI: 10.31234/osf.io/sfmz8_v1
Negative / Null Result ReportOpen accessMedicine

Word length vs. lexical factors: Re-examining what causes the word-length effect in serial recognition.

Guitard D, Neath I, Surprenant AM · 2026 · Memory & cognition

The word-length effect refers to the finding that memory on many short-term/working memory tasks is better for words with fewer syllables than words with more syllables. The standard account attributes this result to a combination of decay…

View details →DOI: 10.3758/s13421-025-01762-5
Negative / Null Result ReportOpen accessMedicine

Effectiveness of an environmental nutrition and physical activity intervention in early childhood education and care settings (NAPSACC UK): a multicentre cluster randomised controlled trial.

Kipping R, Anne Simpson S, Hannam K et al. · 2026 · The Lancet regional health. Europe

Background Early childhood education and care (ECEC) provision is widespread. NAPSACC UK is an intervention in ECECs designed to improve nutrition and physical activity policies, practice and provision through ECEC staff workshops,…

View details →DOI: 10.1016/j.lanepe.2025.101550
Negative / Null Result ReportOpen accessMedicine

Opposing Roles of Testosterone and Cortisol in Prosocial Risk-Taking.

Huang S, Zhang D, Zhuang J · 2026 · Behavioral sciences (Basel, Switzerland)

Prosocial risk-taking is defined as engagement in altruistic behaviors that may have personal costs. Emerging research indicates that testosterone-a gonadal steroid hormone-is linked to behaviors aimed at promoting one's social status. In…

View details →DOI: 10.3390/bs16040568
Negative / Null Result ReportOpen accessMedicine

The effect of trainee career intentions on mentor's interest in the trainee: Experimental evidence from academia.

Smirnova I, Shannon A, Teplitskiy M · 2025 · Research policy

In many industries trainees often seek careers different from their mentors. For example, many PhD students seek non-academic careers. Anecdotally, mentors invest less in different-career trainees, but causal evidence is lacking. To fill…

View details →DOI: 10.1016/j.respol.2025.105232
Negative / Null Result ReportOpen accessMedicine

Social identification and paranoia.

Greenburgh A, Zamperetti L, Bell V et al. · 2024 · Royal Society open science

Paranoia is associated with variation in social behaviour, such as lower inclination to trust others or to behave generously in economic game settings. Such variation may stem, in part, from a reduced tendency to socially identify with…

View details →DOI: 10.1098/rsos.231961