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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21742 results · page 545 of 725

Negative / Null Result ReportOpen accessMedicine

Predicting treatment outcomes by door-to-device time and baseline characteristics in STEMI patients undergoing PPCI: a cross-sectional study in southern Iran.

Vosoughi S, Adineh M, Kardooni A et al. · 2026 · ARYA atherosclerosis

Background Primary percutaneous coronary intervention (PPCI) is considered the gold standard for ST-elevation myocardial infarction (STEMI) treatment. While door-to-device (DTD) time critically influences outcomes, its combined impact with…

View details →DOI: 10.48305/arya.2025.45242.3055
Negative / Null Result ReportOpen accessMedicine

A Retrospective Study of the Presentation, Imaging Findings, and Outcomes in 195 Patients with Maxillofacial Fractures Treated with Closed Reduction or Open Reduction with Internal Fixation.

Durmuş Hİ, Polat ME · 2025 · Medical science monitor : international medical journal of experimental and clinical research

BACKGROUND Maxillofacial fractures represent one of the most common forms of traumatic injuries, affecting both function and aesthetics, and are associated with significant morbidity and long-term sequelae. The incidence and distribution…

View details →DOI: 10.12659/msm.949933
Negative / Null Result ReportOpen accessMedicine

Clinical characteristics, medication use, and mortality outcomes in pediatric chronic kidney disease: A retrospective study at national hospital in Jakarta.

Eff ARY, Yuliana S, Afifah NN et al. · 2026 · Journal of advanced pharmaceutical technology & research

Chronic kidney disease (CKD) in children necessitates the use of a variety of drugs to reduce disease progression and manage complications. Polypharmacy is common in children with CKD, which can increase the occurrence of harmful drug…

View details →DOI: 10.4103/japtr.japtr_207_25
Negative / Null Result ReportMedicine

The relationship between patient activation measure and use of complementary and alternative medicine in oncology patients.

Falkenried J, Ahmadi E, Davitian K et al. · 2026 · Patient education and counseling

Background Complementary and alternative medicine (CAM) is increasingly utilized by cancer patients seeking additional ways to manage their health. Understanding how patient activation influences CAM usage and interest can guide more…

View details →DOI: 10.1016/j.pec.2026.109650
Negative / Null Result ReportMedicine

Shift work, stress, time management and occupational balance: Their associations with job satisfaction among female nurses.

Akyurek G, Gündoğmuş E, Ateş D · 2026 · Work (Reading, Mass.)

BackgroundShift work is a common requirement in healthcare settings to ensure 24-h continuity of care; however, it is associated with increased stress, disrupted circadian rhythms, and decreased job satisfaction among nurses. While…

View details →DOI: 10.1177/10519815261435984
Negative / Null Result ReportMedicine

Daily Associations Between Social Media Exposure and E-Cigarette Use Among Mexican American College Students.

Hébert ET, Bataineh BS, Marti CN et al. · 2026 · Substance use & misuse

Introduction Vaping-related content is prevalent on social media, including industry-sponsored advertising and user-generated content that normalizes use. While previous research suggests a link between social media exposure and vaping,…

View details →DOI: 10.1080/10826084.2026.2670609
Negative / Null Result ReportMedicine

Interpersonal Relationship, Academic Performance, & Life Skills: A Comparative Study of Children With and Without Emotional and Behavioral Problems.

Kheto P, Pallerla S, Bhattacharjee K et al. · 2026 · Clinical child psychology and psychiatry

BackgroundEmotional and behavioral problems (EBPs) in children significantly influence developmental domains, including interpersonal relationships, academic performance, and life skills.MethodsA cross-sectional study was adopted with…

View details →DOI: 10.1177/13591045261446331
Negative / Null Result ReportMedicine

Comparing Self-Reports, Pill Counts, and Electronic Devices in Assessing ART Adherence and its Association with Viral Suppression in Adolescents Living with HIV.

Kizito S, Ssewamala FM, Nabayinda J et al. · 2026 · Journal of acquired immune deficiency syndromes (1999)

Background We compared the performance of self-reports, pill counts, and electronic adherence measures in monitoring antiretroviral therapy (ART) adherence and association with viral suppression among adolescents living with HIV (ALHIV).…

View details →DOI: 10.1097/qai.0000000000003899
Negative / Null Result ReportMedicine

Timing and type of menopause are not risk factors for the onset of diabetes: a UK Biobank cohort study.

Quesada JA, Bertomeu-Gonzalez V, Cordero A et al. · 2026 · Menopause (New York, N.Y.)

Objectives Early and premature menopause are positively associated with coronary heart disease and stroke, but there is less evidence regarding its relationship with the onset of diabetes. The primary objective of this study is to assess…

View details →DOI: 10.1097/gme.0000000000002720
Negative / Null Result ReportMedicine

Vertical Maxillary Movement Is Associated With Incisal Display in Orthognathic Surgery.

Han MD, Shimchuk A, Dosoudil E et al. · 2026 · Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

Background Maxillary incisal display (MID) is a key feature in orthodontic and orthognathic surgical planning that critically impacts esthetics and forms the basis for the vertical positioning of the maxilla. In orthognathic surgical…

View details →DOI: 10.1016/j.joms.2026.04.023
Negative / Null Result Report

Relationship between benzene concentration, MDA levels and kidney function in car painting workshops in Surabaya: A cross-sectional observational study

Tualeka AR, Aziz MY, Perumal V et al. · 2025 · Preprint

Background: Car painting workers are at risk of health problems, particularly kidney disorders, due to exposure to solvents containing benzene as the main ingredient in the car painting process. Therefore, the purpose of this study is to…

View details →DOI: 10.12688/f1000research.140287.3
Negative / Null Result ReportMedicine

Impact of emergency medical services volume on outcomes and management in prehospital traumatic cardiac arrest: a retrospective cohort study.

Morcel B, Yordanov Y, Mercier E et al. · 2026 · Scandinavian journal of trauma, resuscitation and emergency medicine

Background While volume-outcome relationships for non-traumatic out-of-hospital cardiac arrest have been reported in hospital settings, the impact of prehospital exposure, particularly for the rare and clinically complex entity of…

View details →DOI: 10.1186/s13049-026-01622-4
Failed Experiment Report

The Effect of Artificial Intelligence-Assisted Applications on the Perception of Nursing Values and the Mediating Role of Resilience

Cura ŞÜ, Atay S, Çimen M et al. · 2026 · Preprint

Abstract Background Artificial intelligence (AI)-assisted applications are becoming widespread in nursing practice and are creating a significant transformation in care processes. While this transformation may influence nurses’ perceptions…

View details →DOI: 10.21203/rs.3.rs-9039729/v1
Negative / Null Result ReportMedicine

Incidence and Associated Factors of ST-Segment Changes in Noncardiac Surgery Under General Anesthesia.

Gilani MT, Mafi N, Mashhadi L et al. · 2026 · Annals of cardiac anaesthesia

Background Intraoperative cardiac complications may result from an imbalance between myocardial oxygen supply and demand or from plaque rupture. Electrocardiographic (ECG) alterations in the ST-segment observed during surgery or anesthesia…

View details →DOI: 10.4103/aca.aca_243_25
Negative / Null Result ReportOpen accessMedicine

Postoperative Consequences of Fear and Anxiety in Open Heart Surgery: A Comparative Analysis of Two Patient Groups.

Dizdar E, Kiliç A, Alkan Kayhan S et al. · 2026 · The journal of nursing research : JNR

Background Patients undergoing open heart surgery may experience negative emotions such as anxiety, fear, panic, and anger in the preoperative period that may negatively affect their postoperative recovery. Purpose This study was designed…

View details →DOI: 10.1097/jnr.0000000000000721
Negative / Null Result Report

Effect of Material, Number of Yarns and Loop Length on Pressure, Stretchability and Thermal Properties of Seamless Knitted Fabrics for Compression Textiles

Li NW, Kwan M, Yick K · 2026 · Preprint

Compression textiles have been widely applied in medical, sportswear, and daily usage, with single-jersey structures produced by circular knitting dominating the market due to their thinness and light weight. However, the presence of seams…

View details →DOI: 10.20944/preprints202603.0050.v1
Negative / Null Result ReportOpen accessMedicine

Association of TILs and HER2-low status with pathological response in triple-negative breast cancer.

Deliktaş Onur İ, Kurukafa D, Ağyol Y et al. · 2025 · Medicine

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with the lowest treatment success rate. The aim of this study is to determine the relationship between tumor-infiltrating lymphocytes (TILs) score and HER2…

View details →DOI: 10.1097/md.0000000000043971
Negative / Null Result ReportOpen accessMedicine

COVID-19 vaccination remains essential for healthcare professionals: clinical evidence from a Polish cross-sectional study.

Hoffmann K, Michalak M, Jarząb M et al. · 2026 · Frontiers in public health

Introduction Six years after the emergence of SARS-CoV-2, vaccination remains still central to preventing severe COVID-19. The aim was to determine the impact of the vaccine type and number of doses on the course of COVID-19 infection…

View details →DOI: 10.3389/fpubh.2026.1750819
Negative / Null Result ReportMedicine

Associations of 2000 m Rowing Ergometer Performance With Load-Velocity Relationship Variables Obtained During Bilateral and Unilateral Prone Bench Pull and Leg Press.

Pérez-Castilla A, Quidel-Catrilelbún MEL, Baena-Raya A et al. · 2026 · Journal of strength and conditioning research

Abstract Pérez-Castilla, A, Quidel-Catrilelbún, MEL, Baena-Raya, A, Miras-Moreno, S, Conceição, F, Fernandes, JFT, and Ramirez-Campillo, R. Associations of 2000 m rowing ergometer performance with load-velocity relationship variables…

View details →DOI: 10.1519/jsc.0000000000005505
Failed Experiment ReportOpen accessMedicine

The impact of infertility-related stress, physiological stress and some fertility indices on clinical pregnancy in women undergoing in vitro fertilization.

Omidifar N, Najafi E, Nasiri K et al. · 2025 · BMC pregnancy and childbirth

BACKGROUND: Despite numerous studies on the impact of stress on post-in vitro fertilization (IVF) clinical outcomes are contradictory and researchers recommend the need for further studies. Therefore, the purpose of the present study was…

View details →DOI: 10.1186/s12884-025-08280-x
Negative / Null Result ReportMedicine

The Elevated Eosinophil Counts and Neutrophils/Lymphocytes Ratio as Predicting Biomarkers in Non-responders, Chronic Spontaneous Urticarial Patients to Cetirizine/Famotidine Treatment.

Khalili A, Estakhri Z, Shams A et al. · 2026 · Iranian journal of allergy, asthma, and immunology

The responses of patients with chronic spontaneous urticaria (CSU) to regular therapeutic options vary. While these methods are effective for some patients, many do not respond successfully. Despite several studies conducted to identify…

View details →DOI: 10.18502/ijaai.v25i3.21253
Negative / Null Result ReportOpen accessMedicine

The relationship between compassion fatigue and perceptions of spirituality and spiritual care in intensive care unit nurses: a cross-sectional study.

Neşe A, Yiğit B, Bakır E · 2026 · BMC nursing

BACKGROUND: Intensive care units (ICUs) are high-stress environments that significantly predispose nurses to compassion fatigue, affecting both their well-being and the quality of patient care. Spirituality and spiritual care are often…

View details →DOI: 10.1186/s12912-026-04630-y
Negative / Null Result ReportMedicine

Within-individual changes in mitochondrial DNA copy number across the life course and links to individual performance.

Salmón P, Hernandez-Gonzalez M, Boner W et al. · 2026 · Biology letters

Ageing is characterized by complex biological processes reflected in cellular and molecular changes. Mitochondria, which are crucial for energy production and cellular homeostasis, are particularly vulnerable to age-related deterioration.…

View details →DOI: 10.1098/rsbl.2025.0521
Negative / Null Result ReportOpen accessMedicine

Relationship of vitamin D receptor expression with hormone receptors and other clinicopathological features in primary breast carcinomas: A retrospective cross-sectional study.

Ünlü Y, Ömeroğlu E, Ay AS et al. · 2025 · Medicine

Breast cancer is a heterogeneous disease in which estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 play crucial roles in molecular subtyping, diagnosis, treatment, and…

View details →DOI: 10.1097/md.0000000000044222
Negative / Null Result ReportMedicine

Incidence of thromboembolic events in testicular cancer patients receiving cisplatin (TESTCIS study).

Dubois M, Joly M, Dionne A et al. · 2026 · Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

IntroductionDespite the increased incidence of testicular cancer in men aged 15 to 35, patients with this neoplasm have a high five-year survival rate thanks to chemotherapy. However, cisplatin, a drug used in the standard treatment for…

View details →DOI: 10.1177/10781552261445806
Negative / Null Result ReportMedicine

The relationship between individual characteristics and musculoskeletal disorders in tuna fishermen in Pelita Jaya Hamlet, West Seram Regency, in 2024.

Mailuhu JT, Silalahi PY, Maruanaya S et al. · 2025 · International maritime health

Background Indonesia is a country with vast marine areas. It is also part of the world's coral reef triangle, which means that Indonesia has various types of coral reef species. This gives Indonesia a very strong maritime potential.…

View details →DOI: 10.5603/imh.102161