Negative / Null Result ReportMedicine
Hancock G, Batterby E, Dovers E et al. · 2026 · Emergency medicine Australasia : EMA
Background Point-of-care ultrasound (POCUS) is widely used in emergency departments (ED) and has potential value during cardiac arrest for identifying reversible causes (e.g., pericardial effusion, pneumothorax and pulmonary embolism) and…
View details →DOI: 10.1111/1742-6723.70209 Negative / Null Result ReportMedicine
Sun Q, Miao Z, Bian L et al. · 2026 · Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Methionine oxidation in monoclonal antibodies (mAbs) could critically compromise drug stability and efficacy. This investigation comprehensively evaluated the structural and functional impacts of oxidation on a mAb An under long-term…
View details →DOI: 10.1016/j.jchromb.2026.124920 Negative / Null Result ReportMedicine
Messanh KV, Muhie Ddine M, Ambrosini V et al. · 2026 · Journal of photochemistry and photobiology. B, Biology
Botrytis cinerea (B. cinerea) is a fungus with a high mutation rate and infects more than 200 plant species, causing significant yield losses. Therefore, new strategies to fight against this ubiquitous phytopathogen are highly sought…
View details →DOI: 10.1016/j.jphotobiol.2026.113365 Negative / Null Result ReportMedicine
Palner M, Kolesnik E, Baun C et al. · 2026 · Neuropharmacology
Mammalian brain may contain an endogenous pool of the psychedelic substance N,N-dimethyltryptamine (DMT), which may act as a co-transmitter with serotonin (5-HT). We tested the joint hypotheses that endogenous DMT would accumulate in rat…
View details →DOI: 10.1016/j.neuropharm.2026.110874 Negative / Null Result Report
Navez M, Gilbo N, Vandermeulen M et al. · 2026 · Preprint
Abstract Background Kidney transplantation from donation after circulatory death (DCD) donors is increasingly used but remains associated with warm ischemic injury. Normothermic machine perfusion (NMP) enables functional assessment and…
View details →DOI: 10.21203/rs.3.rs-8308681/v1 Negative / Null Result Report
Baltin ME, Shulman AA, Nikulina MI et al. · 2025 · Preprint
Immersive virtual reality (VR) technologies are being increasingly applied in clinical settings, physiotherapy, and neurorehabilitation due to their potential to modulate neurophysiological functions. However, the mechanistic basis of VR’s…
View details →DOI: 10.1101/2025.11.26.690873 Negative / Null Result ReportMedicine
Farber C, Jackson C, Renteria K et al. · 2026 · Nutrition (Burbank, Los Angeles County, Calif.)
Background Exposure to a Western diet during gestation and lactation adversely impacts offspring mood, learning, and memory. We determined if high dose maternal methyl donor nutrient (MDN) supplementation ameliorated the effects of a high…
View details →DOI: 10.1016/j.nut.2026.113149 Negative / Null Result ReportMedicine
Khaliji E, Marycz K, Horna M et al. · 2025 · American journal of veterinary research
Objective To evaluate IA autologous platelet-derived mitochondrial preparation versus vehicle control in a bilateral lipopolysaccharide (LPS)-induced model of equine synovitis. Methods 2 ng of LPS was injected into bilateral intercarpal…
View details →DOI: 10.2460/ajvr.25.05.0187 Negative / Null Result Report
Rodriguez CG, Choolani M, Illanes S · 2025 · Preprint
Objective: To study variation in moral attitudes toward selective abortion in case of prenatal diagnosis of a disability in the general population. Methods: 926 participants completed a survey in which they expressed their moral views…
View details →DOI: 10.31234/osf.io/avs6c_v2 Negative / Null Result Report
Rodriguez CG, Choolani M, Illanes S · 2025 · Preprint
Objective: To study variation in moral attitudes toward selective abortion in case of prenatal diagnosis of a disability in the general population. Methods: 926 participants completed a survey in which they expressed their moral views…
View details →DOI: 10.31234/osf.io/avs6c_v1 Negative / Null Result Report
VanRyzin JW, Laraia GA, Gyawali U et al. · 2025 · Preprint
ABSTRACT Astrocyte dysfunction within the nucleus accumbens (NAc) has been increasingly implicated in maladaptive reward processing and the development of addiction-like behaviors. In this study, we investigated how impairing astrocyte…
View details →DOI: 10.1101/2025.10.20.683571 Negative / Null Result ReportMedicine
Quan F, Ma J, Zhao Y et al. · 2025 · Aquaculture international
This study investigated the effects of supplementing high soybean meal diets with alpha-ketoglutaric acid (AKG) on the intestinal health and growth performance of spotted sea bass (Lateolabrax maculatus). A total of 270 fish (average…
Negative / Null Result ReportMedicine
Zoughaib WS, Fry MJ, Singhal A et al. · 2026 · Medicine and science in sports and exercise
Purpose Increasing nitric oxide bioavailability via nitrate (NO 3- ) ingestion enhances muscle contractility, which may be due to phosphorylation of the regulatory light chain of myosin. If so, there should be an interaction between NO 3-…
View details →DOI: 10.1249/mss.0000000000003932 Negative / Null Result Report
Svigruha R, Yañez-Guerra LA, Caña-Bozada VH et al. · 2025 · Preprint
Abstract Ecdysone-controlled pathways regulate ecdysozoan development through both a nuclear (nEcR) and a membrane receptor (mEcR). Ecdysone signaling was long thought to be exclusive to ecdysozoans; however, studies since 2010 have…
View details →DOI: 10.21203/rs.3.rs-8193722/v1 Negative / Null Result ReportMedicine
Wackernagel D, Gavelli V, Nydert P · 2025 · Clinical nutrition ESPEN
Background & aims In preterm and sick newborn infants, peripherally inserted central catheters (PICC) are used for the delivery of concentrated parenteral nutrition and other high risk drugs. Despite the precaution issued by the ESPGHAN…
View details →DOI: 10.1016/j.clnesp.2025.03.024 Negative / Null Result ReportMedicine
Barbosa MG, Vos DY, Verzijl CRC et al. · 2026 · Cellular and molecular gastroenterology and hepatology
Background & aims Hepatocellular carcinoma is the third leading cause of cancer-related mortality worldwide. Therapeutic options for hepatocellular carcinoma remain limited, and the mechanisms underlying hepatocellular carcinoma are not…
View details →DOI: 10.1016/j.jcmgh.2026.101788 Replication FailureMedicine
Gama de Matos D, de Santana JL, Aidar FJ et al. · 2026 · Journal of clinical medicine
Background : Frailty is a multifactorial condition that significantly impacts older adults' health and independence, which can be mitigated through training. This study examined the effects of a 12-week progressive strength training (PST)…
View details →DOI: 10.3390/jcm15051679 Negative / Null Result ReportMedicine
Li T, Jiang X, Tian X et al. · 2026 · The Journal of endocrinology
Postmenopausal osteoporosis, characterized by estrogen deficiency-induced bone loss and elevated fracture risk, is commonly managed with hormone replacement therapy (HRT). This study aimed to evaluate whether passive exercise via…
View details →DOI: 10.1530/joe-26-0059 Negative / Null Result ReportMedicine
Chen W, Zhang C, Guo W et al. · 2026 · Journal of experimental botany
Apple is an important economic species, but it suffers from biotic stress during its growth and development. Fungi and pests are two types of biotic stress that have significant destructive effects on apple. Members of the leucine-rich…
View details →DOI: 10.1093/jxb/erag089 Negative / Null Result ReportMedicine
Fischer J, Seguel JM, Drole K et al. · 2026 · BMC sports science, medicine & rehabilitation
Background This study investigated the comparative acute effects of 3 × 30 s of vibration foam rolling (VFR) or percussive massage (PM) on the hamstring muscles, specifically range of motion (ROM), maximum voluntary isometric contraction…
View details →DOI: 10.1186/s13102-026-01732-7 Negative / Null Result ReportMedicine
Fujii N, Katagiri A, Nakagome K et al. · 2026 · Scandinavian journal of medicine & science in sports
Continuous monitoring of core temperature is crucial for optimizing exercise performance, promoting health, and ensuring safety. Here, we evaluated the validity of a machine learning-based earbud-type core temperature sensor during…
View details →DOI: 10.1111/sms.70315 Negative / Null Result Report
Lamekina Y, Panela R, Kortje C et al. · 2026 · Preprint
Event segmentation – the division of continuous experience into meaningful units – is essential for understanding narratives. Although event segmentation has been widely studied in visual contexts, little is known about how listeners…
View details →DOI: 10.31234/osf.io/x47cm_v3 Negative / Null Result Report
Lamekina Y, Panela R, Kortje C et al. · 2026 · Preprint
Event segmentation – the division of continuous experience into meaningful units – is essential for understanding narratives. Although event segmentation has been widely studied in visual contexts, little is known about how listeners…
View details →DOI: 10.31234/osf.io/x47cm_v2 Negative / Null Result Report
Selimović-Pašić A, Haglund L, Bensberg M et al. · 2026 · Preprint
The BCL-2 inhibitor venetoclax (VEN) in combination with hypomethylating agents (HMAs) has improved treatment responses in acute myeloid leukaemia (AML), but the mechanisms underlying their synergy remain unclear. We investigated the role…
View details →DOI: 10.64898/2026.04.13.718134 Failed Experiment ReportMedicine
Katanec T, Šimunović L, Likić R et al. · 2026 · Acta stomatologica Croatica
Objective Statins exhibit pleiotropic effects on bone metabolism, including osteogenic and angiogenic activity. The aim of this pilot study was to evaluate whether local application of simvastatin combined with a bovine-derived xenogeneic…
View details →DOI: 10.15644/asc60/2/6 Negative / Null Result ReportMedicine
Maksymowych WP, Weiss PF, Francavilla ML et al. · 2026 · Seminars in arthritis and rheumatism
Objective The OMERACT JAMRIS working group has defined a spectrum of MRI lesions in the sacroiliac joint (SIJ) in pediatric cases with spondyloarthritis (SpA) that match domains for inflammation and structural damage. We aimed to assess…
View details →DOI: 10.1016/j.semarthrit.2026.153018 Negative / Null Result Report
Gama de Matos D, de Santana JL, Aidar FJ et al. · 2025 · Preprint
Background: Frailty is a multifactorial condition that significantly impacts older adults health and independence, which can be mitigated through training. This study examined the effects of a 12-week progressive strength training (PST)…
View details →DOI: 10.20944/preprints202511.1155.v1 Negative / Null Result ReportMedicine
Yang Y, Lan C, Jiang Z · 2026 · Tissue engineering and regenerative medicine
Background This study evaluates the impact of Bacillus subtilis dual-strain enteric-coated capsules combined with vonoprazan-amoxicillin (VA) therapy on Helicobacter pylori (Hp) eradication rates, gastrointestinal symptoms, adverse events…
View details →DOI: 10.1007/s13770-026-00803-7 Negative / Null Result ReportMedicine
Pinheiro-Machado E, Kuiper T, Huurman RH et al. · 2026 · Journal of biomedical materials research. Part B, Applied biomaterials
Polymer scaffolds are a promising platform for the transplantation of insulin-producing cells in Type 1 Diabetes. While vascularization has been a primary focus due to its role in oxygen and nutrient delivery, the interplay between blood…
View details →DOI: 10.1002/jbm.b.70088 Negative / Null Result ReportMedicine
Ten Berg S, Beske RP, Grand J et al. · 2026 · European heart journal. Acute cardiovascular care
Background Noradrenaline is frequently used to increase mean arterial pressure (MAP) in patients with cardiogenic shock caused by infarction-related out-of-hospital cardiac arrest (OHCA-AMICS). This Blood pressure and Oxygenation-Targets…
View details →DOI: 10.1093/ehjacc/zuag045 