Negative / Null Result Report
J Vietheer, C Unbehaun, K Classen et al. · 2019 · European Heart Journal
Abstract Background Graft failure caused by allograft rejection and vasculopathy is the most common cause of mortality after heart transplantation. To detect an early allograft rejection, endomyocardial biopsy is still needed. Tissue…
View details →DOI: 10.1093/eurheartj/ehz746.0235 Negative / Null Result Report
Cassandra Campbell, Kristin Wyckoff, Ronak Naik et al. · 2025 · Pediatric Cardiology
Abstract We sought to determine the impact of the COVID-19 on prenatal diagnosis (PND) of clinically significant congenital heart disease (CHD) and the role of socioeconomic status (SES), complexity of diagnosis, and proximity to advance…
View details →DOI: 10.1007/s00246-025-03844-2 Negative / Null Result Report
Fernando Medrano, Benjamín Gallardo, Pablo Gutiérrez et al. · 2024 · Marine Ornithology
The impact of the El Niño varies across seabirds, usually altering the distribution and causing population declines. Understanding El Niño’s effects is thus critical for conservation. We monitored 296 nests of the little-known Hydrobates…
View details →DOI: 10.5038/2074-1235.52.2.1603 Replication Failure
Haoyu Lian, Siyuan Zhou, Huanyang He et al. · 2026 · Frontiers in Oncology
Objective The purpose of this study was to reveal the genetic correlation of RANKL polymorphisms with bone metastasis in breast cancer patients. Methods In this study, 139 bone metastasis patients and 152 no metastasis were included as the…
View details →DOI: 10.3389/fonc.2026.1788455 Negative / Null Result ReportOpen access
Willy Sandhika, Faroek Hoesin, Dyah Fauziah · 2020
No significant correlation was found between c-erbB2 expression and tumor size (T-stage). c-erbB2 expression in various N-stages were as follows: N0 (80%), N1 (33,3%), N2 (50%), N3 (42,9%). No significant correlation was found between…
Negative / Null Result ReportOpen access
Mismetti, Patrick, Decousus, Hervé, Moulin, Nathalie et al. · 2006
International audienceIn a prospective study, nine patients with phlegmasia caerulea dolens (PCD) related to iliac occlusive thrombosis were treated with intravenous thrombolysis. After thrombolysis, despite no significant improvement in…
Negative / Null Result ReportOpen access
Seung Whan Doo (703584), Young Myoung Ko (703588), Hwa Yeon Sun (3628463) et al. · 2017
Total IPSS and Qmax showed no significant improvement. Storage IPSS and QoL showed significant improvement and PVR showed significant increase. The black diamond signifies that the mean difference is in favor of IPSS. The size of each…
View details →DOI: 10.1371/journal.pone.0169248.g002 Negative / Null Result ReportOpen access
田原, 靖昭, 西澤, 昭, 管原, 正志 et al. · 1991
Aerobic exercise class was opened and blood and physical composition were examined. Results indicated that no significant improvement on measured items was observed. Frequency of participation is suggested to be increased or class goal…
Negative / Null Result ReportOpen access
ÖZGEN ALPAYDIN, AYLİN, Begum GORGULU, Aylin Özgen ALPAYDIN et al. · 2022
Background: Specific breathing exercises are reported to improve quality of life and reduce symptoms; although no significant benefit on lung function or reduction of exacerbation risk is indicated. Additionally, inspiratory muscle…
View details →DOI: 10.30621/jbachs.998416 Negative / Null Result ReportOpen access
· 2011
Mild hypoxia is common after stroke and associated with poor long-term outcome. Oxygen supplementation could prevent hypoxia and improve recovery. A previous study of routine oxygen supplementation showed no significant benefit at 7 and 12…
View details →DOI: 10.1371/journal.pone.0019113 Negative / Null Result ReportOpen access
Khalid Mustafa Ali (4461853), Christine Roffe (220471), Anushka Warusevitane (220475) et al. · 2011
Mild hypoxia is common after stroke and associated with poor long-term outcome. Oxygen supplementation could prevent hypoxia and improve recovery. A previous study of routine oxygen supplementation showed no significant benefit at 7 and 12…
Negative / Null Result ReportOpen access
Akerley, Wallace, Herndon, James E. 2nd, Vokes, Everett E. et al. · 2017
BACKGROUND: In Cancer and Leukemia Group B 39801, we evaluated whether induction chemotherapy before concurrent chemoradiotherapy would result in improved survival and demonstrated no significant benefit from the addition of induction…
View details →DOI: 10.1097/jto.0b013e3181b27b33. Negative / Null Result ReportOpen access
Jiankang Jin (703171), Stephen J. Archibald (703175), Janani Panneerselvam (703170) et al. · 2015
A , RT-PCR analysis showed IL-24 reduced CXCR4 mRNA levels at 6 h and 24 h ( P B , CXCR4 promoter activity was determined using a luciferase reporter vector. Induction of IL-24 showed no significant reduction in luciferase activity…
View details →DOI: 10.1371/journal.pone.0122439.g004 Negative / Null Result ReportOpen access
Andrew W. Taylor (451751) · 2013
The macrophages lysates were assayed for protein concentration and Caspase 3 activity. There was no significant change of Caspase 3 activity in cells treated with α-MSH compared to SFM cells. The graft is the mean ± SD of Caspase 3…
View details →DOI: 10.1371/journal.pone.0074488.g004 Negative / Null Result ReportOpen access
Sandra Demaria (15026216), Shannon Martello (11246282), Molykutty J. Aryankalayil (5544962) et al. · 2020
Metabolic data from PC3 cells 6h, 24h, and 48h after SD or MF radiation. Samples were sent to Metabolon for processing. Results indicate decrease in glycolysis intermediates in SD sample at 6h. No significant changes to TCA cycle…
View details →DOI: 10.1158/1078-0432.22477403.v1 Negative / Null Result ReportOpen access
Hull, Glenn · 2017
This paper determines the effects of police interventions on darknet markets. Darknet markets have been rapidly growing and the amount of drugs being sold on them keeps rising. This paper finds no significant changes in prices of drug…
Negative / Null Result ReportOpen access
Borgers, Sherry, Buenning, Meredith, Farmer, Art et al. · 1980
This research was published by the KU Center for Research on Learning, formerly known as the University of Kansas Institute for Research in Learning Disabilities.The study found that LD adolescents did not differ significantly from non-LD…
Negative / Null Result ReportOpen access
Yuko Yoshimura (283970), Hirotoshi Hiraishi (283977), Mitsuru Kikuchi (140272) et al. · 2015
Two-way ANOVA (treatment × drug) failed to demonstrate any drug or treatment effects, and no significant interaction between these two factors was detected. Therefore, we failed to demonstrate any OT-related effect on…
View details →DOI: 10.1371/journal.pone.0116918.g004 Negative / Null Result ReportOpen access
SPATERNA, Andrea, MECHELLI A., SANTORO D. et al. · 2008
A case of canine cutaneous sterile pyogranuloma/granuloma syndrome (SPGS) with generalized asymmetrical alopecia and plaques is described. Results from histopathologic examination were suggestive of SPGS and failed to demonstrate any…
Negative / Null Result ReportOpen access
Wood, Joanne M. · 2002
It has been suggested that over 90% of the sensory information for driving is visual. Despite this belief, traditional studies have failed to demonstrate that increased crash rates arise from impaired vision. However, more recent studies…
Replication FailureOpen access
Robert H. Biggerstaff · 1973
The study of the Carabelli trait among 199 monozygotic and dizygotic twin pairs failed to demonstrate a high degree of heritability. Analyses of antimere differences in individuals indicated a lack of mirroring and no sexual dimorphism.…
View details →DOI: 10.1177/00220345730520013301 Negative / Null Result ReportOpen access
Grimaud, Dominique, Berthier, Fréderic, Ichai, Carole et al. · 2009
International audienceOBJECTIVES: Traumatic brain injury (TBI) is still a major cause of mortality and morbidity. Recent trials have failed to demonstrate a beneficial outcome from therapeutic treatments such as corticosteroids,…
View details →DOI: 10.1007/s00134-008-1283-5 Negative / Null Result ReportOpen access
Manolis AS, Padeletti L., Mont L et al. · 2008
Dual-chamber (DDD) pacing has generally been regarded as "physiologic pacing" and therefore expected to be superior to ventricular pacing. Major randomized trials have so far failed to demonstrate significant reductions in the incidences…
View details →DOI: 10.1016/j.ahj.2008.05.004 Negative / Null Result ReportOpen access
José M. Ferro, Guilhermina Cantinho, Élia Baeta · 1991
A 45-year-old right-handed man developed “crossed” anomie aphasia, neglect and inaccurate reaching of his left arm in both hemispaces due to a right parietal haemorrhage. Aphasia cleared in a few days. SPECT failed to demonstrate crossed…
View details →DOI: 10.3233/ben-1991-4203 Negative / Null Result ReportOpen access
Manuel Carlos Martins Castro (5255606) · 2022
ABSTRACT Online hemodiafiltration is potentially a superior mode of dialysis compared to conventional hemodialysis. However, prospective randomized controlled trials have failed to demonstrate such superiority. Post-hoc analyses of these…
View details →DOI: 10.6084/m9.figshare.19964391.v1 Failed Experiment ReportOpen access
Jim Sheedy (20157615) · 2009
Mental rehearsal is thought to have positive effects upon the learning and retention of gross motor skills such as those demanded in many sports. A field study using 30 participants from the sport of lawn bowls failed to demonstrate a…
Failed Experiment ReportOpen access
Heyman, S, McAfee, J G, Davis, M A et al. · 1980
Eight neonates with jaundice were studied simultaneously with 99mTc-p-butyl-IDA and 131I-rose bengal. Due to physical decay, 99mTc-p-butyl-IDA failed to demonstrate delayed excretion through the patent extrahepatic biliary tract in 3 of 5…
Negative / Null Result ReportOpen access
Marc Fisher, Ulrich Dirnagl, Geoffrey A Donnan et al. · 2020
Background and Purpose-As a research community, we have failed to demonstrate that drugs which show substantial efficacy in animal models of cerebral ischemia can also improve outcome in human stroke. Summary of Review-Accumulating…
Negative / Null Result ReportOpen access
Claire L. Gibson (6162488), Philip M. Bath (3111867) · 2015
Two multi-centre phase III clinical trials examining the protective potential of progesterone following traumatic brain injury have recently failed to demonstrate any improvement in outcome. Thus, it is timely to consider how this impacts…
Negative / Null Result ReportOpen access
M. Santilli, E. Grieco, ROSSETTI, MARCO et al. · 2014
Low high-density lipoprotein cholesterol (HDL-C) levels are associated with cardiovascular (CV) disease in type 2 diabetes (T2D). Unfortunately available drugs to increase HDL-C have failed to demonstrate a reduction in CV risk. We…
View details →DOI: 10.1016/j.diabres.2013.12.061 