A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21733 results · page 478 of 725
Lewis-Hoeber E, Darainy M, Ebrahimi S et al. · 2026 · Journal of neurophysiology
In verbal memory, retrieval cues can facilitate recall of otherwise inaccessible information. Recent work, using passive movements following a motor learning task, suggests that somatic retrieval cues similarly access motor memories. The…
· 2006
Oxytocin is an essential lactation hormone released during breastfeeding that causes milk ejection and appears to have calming effect on the mother.[1] Administration of exogenous oxytocin to mothers having difficulty in breastfeeding has…
Wynne R, Dharmalingam R, Omarit R et al. · 2026 · Australian critical care : official journal of the Confederation of Australian Critical Care Nurses
Objectives To assess whether high flow nasal oxygen (HFNO) therapy reduces the need for endotracheal intubation in adults with acute hypoxaemic respiratory failure (AHRF) in the intensive care unit (ICU). Methods Systematic reviews were…
Zhang J, Pan Q, Jin L et al. · 2026 · The British journal of ophthalmology
Aims To investigate the effect of switching to a different type of myopia control spectacles on myopia progression. Methods This retrospective matched-cohort study involved 1012 children or adolescents who were prescribed myopia control…
Nagai T, Kuwaki A, Kodama K · 2026 · Nanoscale advances
Developing oxygen reduction reaction (ORR) catalysts with both high catalytic activity and durability is essential for the commercialization of polymer electrolyte fuel cells (PEFCs). One promising strategy to simultaneously enhance the…
Chommaux T, Renault PO, Godard P et al. · 2026 · ACS applied materials & interfaces
The electrical and mechanical behaviors of 400 nm thick indium tin oxide (ITO) thin films on polyimide substrates were investigated by means of electrical resistivity and synchrotron X-ray diffraction (XRD) measurements during equibiaxial…
Vaidie J, Demiselle J, Gabriel A et al. · 2025 · Intensive care medicine
Purpose Decision-making for management of immunosuppressive drugs in solid organ transplant patients admitted to the ICU remains controversial. This study aimed to evaluate the impact of a temporary suspension strategy (interruption of…
Gröning M, Smerup MH, Nissen H et al. · 2026 · Pediatric cardiology
To assess temporal changes in the timing of pulmonary valve replacement (PVR) among patients with tetralogy of Fallot and to determine whether temporal shifts toward earlier PVR were accompanied by differences in ventricular volumes,…
Pascoe B, Cocks K, Clarke N et al. · 2026 · Schizophrenia research
Cognitive impairment associated with schizophrenia (CIAS) is a fundamental symptom of the disorder, which significantly affects individuals' daily functioning and overall quality of life. Currently available antipsychotic drugs have little…
Thimmesch M, Cheping Simo C, Boulay M et al. · 2026 · Revue medicale de Liege
Cystic fibrosis, the most common genetic disorder in Caucasian populations, is caused by mutations in the CFTR gene (Cystic Fibrosis Transmembrane Conductance Regulator), which disrupts chloride ion transport and leads to the production of…
Kloura C, Jensen MM, Ekblond TS et al. · 2026 · Diabetes research and clinical practice
Aim The aim of this exploratory analysis was to investigate effects of time-restricted eating (TRE) on glycemic control and variability in adults with prediabetes. Methods This study utilized data from the Restricted Eating Time (RESET)…
Mommers I, Mubarik S, van Boven JFM et al. · 2025 · BMJ open respiratory research
Background Antibiotics are widely used to manage acute asthma exacerbations, despite little evidence for their effectiveness. This study assesses the added value of antibiotics alongside oral corticosteroids (OCSs) in treating asthma…
Lee BJ, Kim R · 2026 · Preprint
Background: There is a growing interest in the effects of coffee consumption on the human health. This study was conducted to identify a causal relationship between the coffee consumption and the risk of metabolic syndrome (MetS). Methods:…
Toraño P, Balmaseda A, Bordons A et al. · 2025 · Food Microbiology.
Oenococcus oeni is the main species of lactic acid bacteria (LAB) responsible for malolactic fermentation (MLF) in winemaking. MLF development can present difficulties because of the harsh, stressful conditions of wine. Yeast mannoproteins…
Holzhauer CG, Bickar L · 2026 · Alcohol, clinical & experimental research
Background The associations of stress and negative emotion with alcohol use are well established. These associations are mediated by cognitive and psychological mechanisms that may be sex-dependent. This pilot study examined sex…
Lamb CJ, Biedermann BM, Lin EH et al. · 2025 · JSES international
Background Spin in scientific literature is defined as bias that overstates efficacy and/or underestimates harms of an experimental treatment. Glenoid augmentation is a technique used to correct glenoid bone deficiency during shoulder…
Bkaily G, Jazzar A, Jacques D · 2026 · Canadian journal of physiology and pharmacology
Generation of reactive oxygen species (ROS) is a physiological product of cell activity that is mainly generated by the mitochondria as well as by transmembrane NADPH oxidases (NOX1-5) present at the plasma and nuclear envelope membranes.…
Zhou HY, Xin ZM, Lu YY · 2026 · Journal of clinical psychology
Objective Theory of mind (ToM), the ability of mental state attribution, is an important aspect of social cognition. The autism-psychosis diametrical model suggests that there is an opposite impact of autistic traits and psychotic-like…
Cheng J, Li F, Zhang B et al. · 2025 · Bulletin of experimental biology and medicine
We compared the therapeutic effects of dietary adjustment and fish oil in rats with experimental non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet. The NAFLD rats were either maintained on high-fat diet, or transferred…
Clarke JG, Dutta N, Nickel MS et al. · 2026 · ACS medicinal chemistry letters
Semisynthetic modification of mycothiazole ( 1 ) with Meerwein's salt to generate a more stable and/or potent analog than 8- O -acetylmycothiazole ( 2 ) unexpectedly yielded diastereomers devoid of the diene. Analysis of NMR, HR-LCMS, and…
Zhang Z, van Lieshout L, Bekkering H · 2024 · Preprint
When people are offered the opportunity to choose, they tend to learn better. To investigate cognitive mechanisms of this beneficial effect of choice on learning, a learning task was designed in which we independently manipulated choice…
Doneddu PE, Collet-Vidiella R, Gallo C et al. · 2026 · Journal of the peripheral nervous system : JPNS
Background and aims Rituximab has been proposed as a potential treatment in chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), but formal evidence regarding its clinical effectiveness is weak. The CIDPRIT trial found no…
Cavazza M, Carità G, Pizzuto S et al. · 2025 · Preprint
Abstract Background Acute occlusions of the anterior circulation with an underlying intracranial atheromatous disease (ICAD) represent a diagnostic and therapeutic challenge. The aim of this study was to compare the results of the…
Tajika A, Toyomoto R, Sakata M et al. · 2026 · BMJ mental health
Background Depression is a leading cause of global disability, and subthreshold cases contribute substantially to the burden. Cognitive behavioural therapy (CBT) is effective for depressive symptoms, but its impact on social functioning in…
Miletić M, Kovač V, Barišić L et al. · 2025 · Pharmaceutics
Background/Objectives : Resveratrol (RSV) and curcumin (CRC) have antioxidant, anti-inflammatory, photoprotective, and cell-repairing properties. We selected them to investigate the potential role involved in human keratinocyte protection.…
Charles AL, Tetsi L, Quiring G et al. · 2026 · Muscles (Basel, Switzerland)
Peripheral arterial disease is a leading cause of amputation and/or death worldwide. Phosphodiesterase 4 (PDE 4) inhibitors demonstrated beneficial effects in ischemia-reperfusion (IR) settings, but whether PDE 4 inhibition protects…
Li J, Yang C, Li K · 2026 · BMC pregnancy and childbirth
BACKGROUND: Restricted gestational weight gain (GWG) following lifestyle interventions for gestational diabetes mellitus (GDM) has been observed in clinical trials but not been explicitly confirmed in real-world clinical settings.…
Geertsma RC, Polinder J, Groen D et al. · 2025 · Preprint
Abstract Recent reports suggest that reef-building corals can shift from autotrophic to heterotrophic feeding during episodic heatwaves, which may have mitigating effects on thermal stress. It is yet unclear to what extent this could occur…
Stanley M, Huang K, Garlich J et al. · 2025 · Journal of orthopaedic trauma
Objectives To compare time, fluoroscopic utilization, and number of misses for placement of far interlocking screws in tibial and femoral nails using a targeting arm (Targeter) versus perfect circle technique (Control). Methods . Design…
Gewiss C, Gehrdau K, Hischke S et al. · 2025 · Journal of wound care
Objective The application of cold atmospheric plasma (CAP) has been described as a promising therapeutic approach for wound healing. Its use in immunologically mediated wounds such as pyoderma gangrenosum (PG) has not yet been sufficiently…