Negative / Null Result ReportMedicine
Çopur İ, Erbay RH, İlhan S et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : This prospective, randomized study aimed to evaluate the effects of different local anesthetic (LA) volume-dose combinations administered during supraclavicular brachial plexus block (SCBPB), a widely used…
View details →DOI: 10.3390/medicina62061103 Negative / Null Result ReportMedicine
Ekinci EI, Maldonado SG, Unseld A et al. · 2026 · Diabetes, obesity & metabolism
Aims This post hoc analysis evaluated the effect of survodutide on beta-cell function, insulin sensitivity, and glucose biomarkers in two phase 2 trial populations. Materials and methods Trial 1404-0002 randomised 413 participants with…
View details →DOI: 10.1111/dom.70861 Negative / Null Result ReportMedicine
Pyasik M, Marini E, Ippolito G et al. · 2026 · Acta psychologica
In a predictive processing framework, religiosity and spirituality (R&S) have been linked to increased reliance on prior knowledge and decreased prediction error monitoring. In addition, R&S might be differentially related to processing…
View details →DOI: 10.1016/j.actpsy.2026.107185 Negative / Null Result ReportMedicine
Piri K, Gholamzadeh Jofreh M, Haghighizadeh MH et al. · 2026 · BMC psychology
Introduction Fear of childbirth (FOC) is a significant factor contributing to requests for elective cesarean sections. This study aimed to compare the effectiveness of internet-based cognitive behavioral therapy (ICBT) versus in-person…
View details →DOI: 10.1186/s40359-026-04903-w Negative / Null Result ReportMedicine
Dijksterhuis J, Hurmuz MZM, van Dartel D et al. · 2026 · European geriatric medicine
Purpose Older hip fracture patients are often frail, complicating their recovery trajectories. Insight into patients' resilience may help in getting more understanding of their predicted recovery and adjusting their treatment plan…
View details →DOI: 10.1007/s41999-026-01514-x Negative / Null Result ReportOpen accessMedicine
Shanmugasundaram D, Wang RA · 2026 · Journal of toxicology
Objective Zylaria comprises a blend of botanical components, including Xylaria Nigripes (mycelium), Cuscuta Chinensis (seed) and Panax Notoginseng (root). This study aimed to evaluate the potential toxicity of Zylaria when administered…
View details →DOI: 10.1155/jt/6989296 Negative / Null Result ReportOpen accessMedicine
Motomura T, Higashi M, Hattori A et al. · 2026 · Internal medicine (Tokyo, Japan)
Objective Hyperuricemia is associated with cardiovascular disease and chronic kidney disease (CKD). Dotinurad is a new uricosuric drug that has not been evaluated in clinical trials in patients with advanced CKD (CKD G3b-G5). This study…
View details →DOI: 10.2169/internalmedicine.5834-25 Negative / Null Result ReportMedicine
Pedersen TA, Mori Y, Botteri E et al. · 2026 · Endoscopy
Background The effect of computer-aided detection (CADe) on performance of endoscopists with different experience levels is not well understood. This study assessed whether CADe use promotes learning or deskilling. Methods We performed a…
View details →DOI: 10.1055/a-2858-7084 Negative / Null Result ReportMedicine
Hoskens S, Bamps K, Herteleer M · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Objectives The percutaneous placement of iliosacral (IS) and transsacral (TS) screws has become a standard practice for the treatment of pelvic fractures. Due to the complex sacral anatomy, accurate screw placement is essential to avoid…
View details →DOI: 10.1007/s00590-026-04768-0 Negative / Null Result Report
Sacconi R, Saladino S, Forte P et al. · 2026 · Preprint
Abstract There is a lack of knowledge about the effect of smoking activity on the anatomy and functionality of retinal vessels. The aim of this low-risk, single-center, case-control, interventional clinical trial (ClinicalTrials.gov ID…
View details →DOI: 10.21203/rs.3.rs-8916335/v1 Negative / Null Result Report
Cagini C, Messina M, Fiore T et al. · 2026 · Preprint
Abstract Purpose This study investigates the efficacy of a liposomal ophthalmic solution containing cross-linked hyaluronic acid, trehalose, and stearylamine in reducing the occurrence of dry eye-like signs and symptoms in patients…
View details →DOI: 10.21203/rs.3.rs-9533021/v1 Negative / Null Result ReportMedicine
Lu J, Shorey A, Uduba R et al. · 2026 · Clinical transplantation and research
Background Up to 23% of renal transplant recipients may develop transplant renal artery stenosis (TRAS). However, diagnosis requires angiography, and the contrast used may be nephrotoxic. We aimed to identify predictors of TRAS and clarify…
View details →DOI: 10.4285/ctr.25.0052 Negative / Null Result ReportMedicine
Feng J, Li S, Li X et al. · 2026 · Journal of agricultural and food chemistry
The effects of dietary supplementation with conjugated linoleic acid (CLA) on broiler duck growth performance and the quality of dry-cured products were investigated. Ten days preslaughter with the supplementation of 2 mL/d CLA was more…
View details →DOI: 10.1021/acs.jafc.6c02008 Negative / Null Result ReportOpen accessMedicine
To B, Prasath V, Veney D et al. · 2026 · NPJ breast cancer
Circulating tumor DNA (ctDNA) 'tumor fraction' (TF) may correlate with therapy response, but little is known regarding TF dynamics immediately after therapy initiation. Plasma samples from a single-arm clinical trial enrolling patients…
View details →DOI: 10.1038/s41523-026-00953-w Negative / Null Result ReportMedicine
Mace C, Deighton R · 2026 · Death studies
Empirical evidence is lacking on the effectiveness of grief telephone counseling, particularly in Australia. This study addresses an important gap by evaluating the effectiveness of the Integrating Grief Program-Victoria (IGP-V), an…
View details →DOI: 10.1080/07481187.2026.2646872 Negative / Null Result ReportMedicine
Ajai S, Agnihotri R · 2026 · Journal of dental hygiene : JDH
Purpose Recently, charcoal-based oral hygiene products, such as toothpastes, have gained popularity due to their whitening and antibacterial properties. However, there is limited data on charcoal-bristle electric toothbrushes. The purpose…
Negative / Null Result ReportMedicine
Lee BC, Lee J, Cho KH et al. · 2026 · Gerontology
Introduction Sarcopenia and osteosarcopenia are increasingly prevalent among older adults. Exercise and nutritional support are key non-pharmacological treatments; however, their benefits may diminish after discontinuation. This study…
View details →DOI: 10.1159/000552519 Negative / Null Result Report
Ma P, Wu Q, Xin W et al. · 2026 · Preprint
Purpose Comparison of ocular parameters (ACD, AL, LT, VL, CCT, ASD, LC, LT/ACD) in preterm infants with retinopathy after treatment, those with spontaneous regression, and those without retinopathy, at postmenstrual (ages of 0 (40 weeks),…
View details →DOI: 10.64898/2026.05.14.26353221 Negative / Null Result ReportOpen accessMedicine
Nalbant A, Olgun HE, Hendek M et al. · 2026 · Lasers in medical science
The aim of this study was to compare the effectiveness of diode laser and combined treatment protocols, applied in addition to mechanical debridement, in the treatment of peri-implantitis on clinical periodontal parameters and S100A8…
View details →DOI: 10.1007/s10103-026-04925-1 Negative / Null Result ReportMedicine
Baek CH, Lim C, Kim JG et al. · 2026 · Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
Background Cystic changes within interpositional grafts used for arthroscopy-assisted lower trapezius tendon transfer (aLTT) are occasionally detected on postoperative magnetic resonance imaging (MRI); however, their clinical significance…
View details →DOI: 10.1016/j.jos.2026.04.009 Negative / Null Result ReportMedicine
Fattahi F, Abed S, Kouchakali G et al. · 2026 · Molecular neurobiology
Introduction Alzheimer's disease (AD) is a progressive neurological disorder associated with high prevalence. Numerous studies have been conducted to regulate the expression of inflammatory genes, indicating that any changes may ultimately…
View details →DOI: 10.1007/s12035-026-05821-z Negative / Null Result ReportMedicine
Caple MA, Lau JA · 2025 · Proceedings. Biological sciences
Local adaptation is widely documented, but contributing selective agents are rarely identified or disentangled. Here, we test whether plants are adapted to their local soil nitrogen conditions and whether microbes mediate plant adaptation…
View details →DOI: 10.1098/rspb.2025.2019 Negative / Null Result ReportOpen accessMedicine
Muñoz-Vendrell A, Arroyo-Pereiro P, León I et al. · 2026 · Journal of neurology
Background Subcutaneous natalizumab offers greater convenience than intravenous administration, but pharmacokinetic differences have raised concerns about potential subclinical disease activity. Serum neurofilament light chain (sNfL) and…
View details →DOI: 10.1007/s00415-026-13949-0 Failed Experiment ReportMedicine
Boegl M, Kasper I, Dewailly D et al. · 2026 · Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
Objective Up to 50% of women with functional hypothalamic amenorrhea (FHA) exhibit polycystic ovarian morphology (PCOM) on ultrasound. We aimed to compare the hormonal response to ovulation induction with pulsatile GnRH therapy in FHA…
View details →DOI: 10.1080/09513590.2026.2677994 Negative / Null Result ReportMedicine
Zhao L, Zeng C, Jia X et al. · 2026 · Medicine
Breast cancer (BC) has the highest cancer incidence and mortality in women worldwide, and the relationship between serum enzymes and BC has been inconsistent in previous observational studies. In this paper, 2-sample Mendelian…
View details →DOI: 10.1097/md.0000000000049516 Negative / Null Result ReportMedicine
Al-Mohana RAAM, Jianping H, Alhammadi MS et al. · 2026 · Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
Objective To elucidate the pattern and extent of long-term condylar adaptation within the temporomandibular joint (TMJ) following mandibular setback by bilateral sagittal split osteotomy (BSSO) in patients with mandibular prognathism, with…
View details →DOI: 10.1016/j.jcms.2026.104622 Negative / Null Result ReportMedicine
Kubota H, Makino Y, Yoshida M et al. · 2026 · International journal of legal medicine
Background It is important to understand post-mortem changes in post-mortem computed tomography (PMCT) image interpretation. Only a few studies have focused on the eyeballs. This study aimed to clarify the changes in eyeball findings on…
View details →DOI: 10.1007/s00414-026-03829-7 Negative / Null Result ReportOpen accessMedicine
Lu Y, Shu L, Liu C et al. · 2026 · Frontiers in cardiovascular medicine
Background Ethanol infusion of the vein of Marshall (EIVOM) has emerged as a promising adjunct to pulmonary vein isolation (PVI) for atrial fibrillation (AF). Methods Patients undergoing catheter ablation for persistent AF (>3 months) were…
View details →DOI: 10.3389/fcvm.2026.1807237 Negative / Null Result ReportMedicine
Kocaman Y, Yanmaz LE · 2026 · Veterinary ophthalmology
Purpose This study aimed to evaluate the effects of ivermectin administration on aqueous tear production and ocular surface health in dogs and to investigate its potential association with quantitative keratoconjunctivitis sicca (KCS).…
View details →DOI: 10.1111/vop.70180 Negative / Null Result ReportMedicine
Lin YJ, Chen QY, Zhao SY et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose This study investigated the clinical characteristics and prognosis of rhegmatogenous retinal detachment (RRD) in patients with implantable collamer lens (ICL). Methods A retrospective review was conducted of medical records from…
View details →DOI: 10.1097/iae.0000000000004772 