A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21321 results · page 433 of 711
Barghash M, Obayi E, Itaman U et al. · 2025 · Cureus
Background Hiatal hernia is commonly associated with gastro-oesophageal reflux disease (GORD). However, the relationship between hernia size and reflux severity remains unclear. This study aimed to assess the impact of the hiatal hernia…
Md Kasim NA, Shirinal Izuan US, Karuppannan M · 2026 · BMC health services research
BACKGROUND: Healthcare providers commonly recommend medication reminders as a strategy to enhance adherence to prescribed medications. Patient demographic characteristics may influence medication adherence and incorporating patient-centred…
Prates AJ, Curioni OA, Ramos DM et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives: Laryngeal cancer has a high incidence and mortality rate, especially in advanced stages. Stoma recurrence after total laryngectomy is rare but lethal, and its risk factors remain controversial. We aimed to assess…
Voigt MB, Böhner A, Bahaaeldin M et al. · 2026 · CVIR endovascular
To evaluate the occurrence of periaortic inflammation, including abscess formation, as a complication following endoleak repair after endovascular aortic repair. This retrospective single-center study analyzed 88 EVAR revisions for…
Zhao N, Zhan Y, Choi J et al. · 2026 · The Journal of nutrition
Background The consumption of live microbes beyond probiotics is associated with health benefits. Despite growing interest in live microbe intake, comprehensive data on its dietary sources and research on their potential health effects in…
Mostafavi M, Rezazadeh F, Fattahi MJ et al. · 2026 · Journal of dentistry (Shiraz, Iran)
Background Multiple studies have revealed an association between vitamin D levels, genetic polymorphisms of the VDR (vitamin D receptor) gene, and the underlying causes of various bone and cartilage disorders. Purpose This study aimed to…
Ozaki K, Nishioka Y, Kamitani F et al. · 2026 · Diabetes research and clinical practice
It has been controversial whether COVID-19 increases the risk of new-onset type 1 diabetes mellitus. Using large-scale claims data, we found no statistically significant association between COVID-19 and incident type 1 diabetes mellitus in…
Buran A, Altaş H, Özkaya Uçar Y et al. · 2026 · Journal of the Turkish German Gynecological Association
Objective To evaluate pathological findings in patients positive for human papillomavirus (HPV)-31. Material and methods This retrospective study included patients evaluated in a tertiary colposcopy clinic. The 3,546 patients tested for…
Braun S, Selkridge I, Nocon A et al. · 2026 · Arthroplasty (London, England)
Background Extensor mechanism disruption following total knee arthroplasty (TKA) significantly impairs knee function and quality of life. Extensor mechanism reconstruction (EMR) is effective but carries risks, including post-operative…
Sarpeleh F, Ehtesham N, Mirjani R et al. · 2026 · Lupus
ObjectiveThe dysfunction of interleukin-7 receptor alpha (IL-7Rα), which is encoded by the IL7RA gene, has been implicated in the development of systemic lupus erythematosus (SLE). This study aimed to investigate the relationship between…
Mazurek A, Jankowski M, Grudziąż-Sękowska J · 2026 · BMC nephrology
BACKGROUND: The weekend effect refers to the observation that patients admitted to the hospital on the weekend experience poorer clinical outcomes than patients admitted during the workweek. This effect has not been previously studied…
Chen JSC, Osborne JWA, Menz HB et al. · 2026 · Journal of foot and ankle research
Background Fatty infiltration, or fatty atrophy, of the abductor digiti minimi (ADM) muscle of the foot is proposed to be associated with entrapment of the first branch of the lateral plantar nerve (i.e., Baxter's neuropathy) as part of…
Millán J, Gal B, Esquerda M et al. · 2026 · BMC medical education
Background In Spain, access to specialized medical training is determined through a highly competitive national examination (MIR). While the educational climate of medical schools has been associated with students' learning outcomes and…
Zhong R, Chen S, Cui N et al. · 2026 · Preprint
Abstract Background: Adolescents diagnosed with depression frequently experience anxiety and other psychological symptoms. Yet, the interrelationships among multiple psychological symptoms are under-investigated. Network analysis is a…
Mahaboob L, Chehade H, Gnanamuthu SS et al. · 2026 · Preprint
Abstract Background Fast-food consumption has become increasingly prevalent among university students, contributing to unhealthy dietary patterns and rising obesity rates. Understanding students' fast-food consumption habits, knowledge,…
Vejdani-Jahromi M, Calle E, Ganem O et al. · 2026 · AJNR. American journal of neuroradiology
Background and purpose Alzheimer disease (AD) is a progressive neurodegenerative disorder that predominantly affects the aging population. Anti-amyloid β (anti-Aβ) therapies, such as lecanemab, have been developed to slow disease…
Brown J, Abdullah N, Sobuwa S · 2026 · International journal of emergency medicine
BACKGROUND: Endotracheal intubation is a critical life-saving intervention in prehospital emergency care, yet evidence supporting its safe implementation by prehospital practitioners in lower- to middle-income countries remains limited.…
Lukies M, Darby O, Wani S et al. · 2026 · Journal of medical imaging and radiation oncology
Uterine artery embolisation (UAE) is an evidence-based treatment for symptomatic fibroids and adenomyosis. Ultrasound is commonly utilised for assessment post UAE given its wide availability and low cost; however, contemporary studies…
Karatutlu AS, Karatutlu MA, Aydin S · 2026 · Renal failure
Chronic kidney disease (CKD) is characterized by progressive renal fibrosis and irreversible loss of kidney function. Decorin, an extracellular matrix proteoglycan with antifibrotic properties, may reflect underlying fibrotic activity and…
Xu G, Li X, Song G et al. · 2026 · Frontiers in sports and active living
Background Poor sleep quality and anxiety are prevalent among university students and pose growing public health concerns. Physical fitness is often assumed to be associated with better sleep and mental health outcomes; however, evidence…
Tel Adigüzel K, Atasoy S, Güler B et al. · 2026 · Nutrition and health
BackgroundMuscle strength is a key determinant of functional capacity and quality of life, influenced by various modifiable factors including nutrition. Emerging evidence suggests a potential link between dietary acid load and…
Vatansever A, Erçakmak Güneş B, Günenç Beşer C et al. · 2026 · Medicine
The cerebellar tentorium, composed of 2 laminae of dura mater, is an essential structure that separates the posterior and middle cerebral fossae. As it has a dural sinus within its 2 laminae, it carries significant risk potential. Cranium…
Pan S, Xiao L, Li Y et al. · 2026 · BMC infectious diseases
Objective The objective of this study was to investigate the changes of Myeloid-derived suppressor cells (MDSCs) and cytokines expression during mother-to-child blockade in chronic HBV infected patients. Method This was a single-center,…
Amelia P, Tobing TC, Adriansyah R et al. · 2026 · Preprint
Abstract Background: Children with congenital heart disease (CHD) are at risk of impaired quality of life (QoL) due to hemodynamic burden and nutritional disturbances. Thiamine plays an essential role in myocardial energy metabolism, but…
Saygin I, Usta ZT, Akbas A et al. · 2026 · Turk patoloji dergisi
Objective Colorectal cancer (CRC) is the third most common type of cancer worldwide and the fourth most common cause of cancer-related deaths. Innovative approaches like immunotherapy are necessary for treatment-resistant patients with a…
Hao L, Ju W, Huang Y · 2026 · The Journal of dermatological treatment
Background Photodynamic therapy (PDT) is an effective treatment for port-wine stains (PWS). However, the relationship between the diameter of malformed capillaries and the efficacy of PDT in PWS has been rarely studied. Objective This…
Wen LH, Siang JYD, Yee LF et al. · 2026 · Preprint
Abstract Objectives To investigate the incidence and factors influencing retinal displacement as well as functional visual outcomes following rhegmatogenous retinal detachment (RRD) repair. Methods A prospective observational study which…
Aslam A, Kamran M, Siddiqui S · 2026 · Frontiers in public health
Introduction One of the most widely studied topic in the educational research is teacher's wellbeing and rightly so, as resilient and well-supported teacher serves as an essential pillar for creating an effective and durable educational…
Dogruoz F, Askin A, Ergun A et al. · 2026 · Journal of clinical medicine
Background/Objectives: The extent to which patient-reported outcome measures (PROMs) reflect objective functional recovery after surgical repair of acute Achilles tendon rupture remains unclear. This study aimed to evaluate the…
El Habashy HR, Ahmed SM, Al Salmawy DA et al. · 2026 · Neurological research
Background Bell's palsy (BP) is the most common acute peripheral mononeuropathy worldwide. While electrodiagnostic studies are established tools for functional assessment, high-resolution ultrasonography (HRUS) has emerged as a…