Negative / Null Result ReportMedicine
Chen, Spadaccini, Sahai et al. · 2026 · Endoscopy international open
Endoscopic ultrasound-guided choledochoduodenostomy using a lumen-apposing metal stent (EUS-CDSL) has been shown in randomized controlled trials (RCTs) to be effective compared with endoscopic retrograde cholangiopancreatography (ERCP) in…
View details →DOI: 10.1055/a-2863-1621 Failed Experiment ReportMedicine
Ren, Nan, Li et al. · 2026 · Annals of medicine
To evaluate the analgesic efficacy of thoracic paravertebral block (TPVB) with different doses of liposomal bupivacaine (LB) or ropivacaine in patients undergoing single-port thoracoscopic lung surgery. A total of 105 patients scheduled…
View details →DOI: 10.1080/07853890.2026.2687941 Failed Experiment ReportMedicine
Gauci, Millet, Jacquot et al. · 2026 · Journal of shoulder and elbow surgery
The efficacy of patient-specific guides (PSGs) in improving accuracy and reducing the number of outliers in glenoid implant positioning in anatomic total shoulder arthroplasty has been clearly shown. However, long-term clinical benefit in…
View details →DOI: 10.1016/j.jse.2026.06.018 Negative / Null Result ReportMedicine
Kim, Seo, Nam et al. · 2026 · Cancer research and treatment
Preclinical studies suggest that sodium-glucose cotransporter-2 inhibitors (SGLT-2is) may have cancer-preventive effects; however, clinical evidence remains inconclusive. Therefore, this study aimed to evaluate the association between the…
View details →DOI: 10.4143/crt.2025.1243 Negative / Null Result ReportMedicine
Huang, Xu, Qin et al. · 2026 · Lancet (London, England)
Successful reperfusion after endovascular thrombectomy does not consistently result in functional independence in acute ischaemic stroke. We aimed to assess the efficacy and safety of tirofiban, a glycoprotein IIb/IIIa receptor antagonist,…
View details →DOI: 10.1016/s0140-6736(26)00983-9 Negative / Null Result ReportMedicine
Harris, Housman · 2026 · Applied neuropsychology. Adult
Neuropsychological performance is influenced by demographic/premorbid factors in addition to acquired cognitive impairment. This study examined relationships between educational attainment, reading ability, and executive functions in a…
View details →DOI: 10.1080/23279095.2026.2693225 Negative / Null Result ReportMedicine
Pan, Luan, Zhang et al. · 2026 · PloS one
Scale-Invariant Feature Transform (SIFT) features are widely used in target recognition and tracking. This study aimed to exploit the robust performance of the SIFT algorithm to accurately calculate tumor tissue displacement during…
View details →DOI: 10.1371/journal.pone.0330578 Negative / Null Result ReportMedicine
Peretó Villaescusa, Coelho, Grillo et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Postoperative knee stiffness following total knee arthroplasty (TKA) is a challenging complication that may require surgical intervention when conservative treatment fails. Although manipulation under anesthesia (MUA) and arthroscopic…
View details →DOI: 10.1007/s00590-026-04838-3 Negative / Null Result ReportMedicine
Heigl, Paganetti, Honaker et al. · 2026 · Langenbeck's archives of surgery
The feasibility and impact of Enhanced Recovery after Surgery (ERAS) protocols in emergency settings remain poorly understood due to patient instability, limited preoperative optimization, and inconsistent protocol adherence. Therefore,…
View details →DOI: 10.1007/s00423-026-04114-2 Negative / Null Result ReportMedicine
Fajriani, Djawad, Tabri et al. · 2026 · Dermatology reports
Xerosis is a prevalent skin disorder among patients with chronic kidney disease (CKD) undergoing hemodialysis (HD). While both Aloe vera cream 30% and urea cream 20% have been shown to improve skin hydration in cases of xerosis cutis,…
View details →DOI: 10.4081/dr.2026.10496 Negative / Null Result ReportMedicine
Fahmy, El-Geleel, Anwar et al. · 2026 · Journal of the American Dental Association (1939)
Caries is the most prevalent chronic disease in children, affecting more than 530 million people worldwide. Timely restoration of primary molars is critical for maintaining function and preventing premature tooth loss. The choice of…
View details →DOI: 10.1016/j.adaj.2026.03.026 Negative / Null Result ReportMedicine
Jesus, Alves, Resende · 2026 · CoDAS
To validate and standardize the online application of the Scale of Self-Perception of Central Auditory Processing Skills (EAPAC) - expanded for Brazilian adults. The EAPAC was expanded and answered by 1,274 Brazilian individuals aged 18 to…
View details →DOI: 10.1590/2317-1782/e20250215pt Negative / Null Result ReportMedicine
Inoue, Ono, Okazaki et al. · 2026 · Cureus
Objectives Early prediction of neurological outcomes in patients with out-of-hospital cardiac arrest (OHCA) is critical for guiding treatment decisions. Machine learning (ML) model and grey-white matter ratio (GWR), both derived from brain…
View details →DOI: 10.7759/cureus.109468 Negative / Null Result ReportMedicine
Kataruka, Sannyashi, Bhattacharjee et al. · 2026 · Cureus
Neuropathic ulcers occur mainly at the plantar aspect and correspond to areas with peak plantar pressure, usually seen in a sensory-deficient foot. Trophic ulcers are seen in diabetic neuropathy, post-leprosy, and any other neurological…
View details →DOI: 10.7759/cureus.109479 Negative / Null Result ReportMedicine
Harvey, Morita, Huynh et al. · 2026 · JMIR medical informatics
Health care providers spend an excessive amount of time within electronic medical record (EMR) systems documenting patient encounters, often amounting to hours of work outside of regular office hours. This affects physician productivity…
View details →DOI: 10.2196/84104 Negative / Null Result ReportMedicine
Bala, Akyazi, Eraslan et al. · 2026 · BMC veterinary research
Environmental noise is a non-specific stressor that can activate stress-response pathways and increase the production of reactive oxygen species, contributing to oxidative stress in the brain. Limbic regions such as the amygdala and…
View details →DOI: 10.1186/s12917-026-05658-7 Negative / Null Result ReportMedicine
Chen, Wen, Zheng · 2026 · Shock (Augusta, Ga.)
Sepsis is a clinical syndrome marked by a dysregulated host response to infection, impairing oxygen delivery and utilization and causing organ dysfunction. Hypoxemia, which can cause significant tissue and organ damage, commonly occurs in…
View details →DOI: 10.1097/shk.0000000000002865 Negative / Null Result ReportMedicine
Mod, Keskin, Can et al. · 2026 · International journal of impotence research
This study aimed to compare the effects of absorbable and non-absorbable sutures on postoperative erectile function, ejaculatory function and sexual satisfaction in patients undergoing penile fracture repair. In this single-center…
View details →DOI: 10.1038/s41443-026-01313-9 Negative / Null Result ReportMedicine
Fazal, Loya, Muayad et al. · 2026 · American journal of ophthalmology
Age-related macular degeneration (AMD) is a leading cause of central vision loss worldwide. Emerging evidence suggests that targeting dopaminergic pathways may influence AMD progression. This study evaluates whether levodopa ±…
View details →DOI: 10.1016/j.ajo.2026.06.037 Negative / Null Result ReportMedicine
Eroğlu, Taş, Ekici · 2026 · Zeitschrift fur Orthopadie und Unfallchirurgie
In hemiplegic patients, joint cartilage alterations may arise from impaired balance reactions, decreased selective motor control, abnormal muscle tone, or reduced weight shifting toward the affected limb. This study aimed to investigate…
View details →DOI: 10.1055/a-2887-2112 Negative / Null Result ReportMedicine
Seehra, Ellis, Doleman et al. · 2026 · Journal of surgical education
Compare the demographics of UK surgical trainees and Annual Review of Competence Progression (ARCP) panel members to assess proportional representation. Retrospective cross-sectional analysis of national trainee and assessor records, with…
View details →DOI: 10.1016/j.jsurg.2026.104018 Negative / Null Result ReportMedicine
Levine, Lyons, Chatha et al. · 2026 · Surgical laparoscopy, endoscopy & percutaneous techniques
Paraesophageal hernias are a prevalent medical condition often treated with surgical intervention, and decisions regarding hernia sac management are involved. Sac excision during PEH repair has emerged as a viable and safe management…
View details →DOI: 10.1097/sle.0000000000001470 Negative / Null Result ReportMedicine
Dharia, Plietz, Hahn et al. · 2026 · International journal of colorectal disease
The aim of this study was to assess the impact of diversion proctitis (DP) between the first and second surgical stage on pouch outcomes in patients with ulcerative colitis (UC) who underwent three-stage restorative proctocolectomy (RPC)…
View details →DOI: 10.1007/s00384-026-05182-y Negative / Null Result ReportMedicine
Goodman-Williams, Smith, Volz et al. · 2026 · Journal of interpersonal violence
Many sexual assault victims choose not to report their assault to police, and identifying characteristics that predict non-reporting can highlight areas for improvement in the criminal legal system's response to sexual assault. In the…
View details →DOI: 10.1177/08862605261455557 Negative / Null Result ReportMedicine
Zhipeng, Bing, Dongli et al. · 2026 · The American journal of gastroenterology
With the increasing frequency of electrocoagulation hemostasis used in endoscopic submucosal dissection (ESD), the incidence of postoperative bleeding is gradually decreasing, while the incidence of post-ESD electrocoagulation syndrome…
View details →DOI: 10.14309/ajg.0000000000004089 Negative / Null Result ReportMedicine
Itaya, Sano, Kajiwara et al. · 2026 · BMC pharmacology & toxicology
We previously reported that mirogabalin, a selective voltage-gated calcium channel α2δ1/α2δ2 ligand, increases the proliferative potential of pancreatic cancer. However, the risk of pregabalin, a non-selective…
View details →DOI: 10.1186/s40360-026-01176-2 Negative / Null Result ReportMedicine
Wu, Xu · 2026 · Medicine
This study aims to compare the consistency of the Gleason score after radical prostatectomy between cognitive multi-parametric magnetic resonance imaging (mpMRI)-guided transperineal ultrasound-guided transperineal prostate biopsy…
View details →DOI: 10.1097/md.0000000000049053 Negative / Null Result ReportMedicine
Meskó, Davis, Arnocky et al. · 2026 · Archives of sexual behavior
In the context of mating, individuals of the same sex often act as rivals in the pursuit, attraction, and retention of desirable partners. This study explored the relationships between intrasexual competition and various aspects of human…
View details →DOI: 10.1007/s10508-026-03464-8 Negative / Null Result ReportMedicine
Katheria, Lakshminrusimha, Morales et al. · 2026 · Pediatric research
We sought to evaluate oxidative changes in premature infants receiving 100% oxygen compared with 30% during deferred cord clamping (DCC). Premature infants born at 22 0/7 to 28 6/7 weeks received DCC in conjunction with either 30% (LO…
View details →DOI: 10.1038/s41390-026-05199-7 Negative / Null Result ReportMedicine
Beverstock, Hagan, Fernandes et al. · 2026 · Journal of perinatology : official journal of the California Perinatal Association
To assess for differences in congenital diaphragmatic hernia patient characteristics between those requiring single or multiple intubation attempts, and to determine the relationship between number of intubation attempts and time to…
View details →DOI: 10.1038/s41372-026-02759-x 