A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21321 results · page 432 of 711
Sæther, Butt, Eubank et al. · 2026 · Frontiers in psychology
Psychological stressors have become a natural part of the process of developing skills in talent development environments of youth athletes. However, there is little research on psychological stressors among talented female athletes and…
Jamei-Martel, Garibaldi, Castroviejo Fernández et al. · 2026 · JSES international
The optimal management of high-grade acromioclavicular (AC) joint dislocations remains controversial. While surgical treatment improves radiographic alignment, its impact on functional outcomes remains debated. This study prospectively…
Huang, Yin, Lin · 2026 · Transplantation proceedings
The utilization of hepatitis B surface antigen-positive (HBsAg+) living kidney donors is a strategy to expand the donor pool. However, concerns regarding their renal safety after nephrectomy persist due to the potential impact of chronic…
Foster, Millist, Germaine et al. · 2026 · Epilepsia open
ES-481 is a novel potent and selective antagonist of TARP-y8-dependent AMPA receptors. We aimed to assess the potential efficacy, safety and tolerability, and pharmacokinetics of different doses of ES-481 as an add-on anti-seizure…
Ucan Gunduz, Nizam Tekcan, Erdem et al. · 2026 · Journal of pediatric ophthalmology and strabismus
To investigate microstructural alterations in the retina, choroid, and optic nerve head in children with spina bifida using optical coherence tomography. Thirty-eight children with spina bifida and 32 children without spina bifida were…
Zamaniyan, Abbasi, Habibpour et al. · 2026 · International journal of reproductive biomedicine
Diminished ovarian reserve is one of the most important issues in in vitro fertilization cycles. Some authors have reported beneficial effects of dual triggering in women with poor ovarian response, whereas other investigators have…
Alencar, Teles, Cunha et al. · 2026 · Revista brasileira de ortopedia
Artificial intelligence (AI) tools based on natural language, such as ChatGPT 4.1 mini (OpenAI Group PBC) and Gemini 2.5 Flash (Alphabet Inc.), are used by patients as sources of medical information. The current study aimed to evaluate and…
Alencar, Teles, Cunha et al. · 2026 · Revista brasileira de ortopedia
Artificial intelligence (AI) tools based on natural language, such as ChatGPT 4.1 mini (OpenAI Group PBC) and Gemini 2.5 Flash (Alphabet Inc.), are used by patients as sources of medical information. The current study aimed to evaluate and…
Petrina, Dong, Beamer et al. · 2026 · Open forum infectious diseases
Vaginal dysbiosis is associated with HIV acquisition and preterm delivery. Our objective was to evaluate prevalent vaginal infections, and changes in microbiota and cytokines among pregnant and breastfeeding women from 4 African countries…
Hardika, Kurniawan, Laksmi et al. · 2026 · Journal of the ASEAN Federation of Endocrine Societies
Leukocyte telomere length (LTL) is considered a biomarker of cellular senescence. Previous studies have reported the associations between shortened telomere length and type 2 diabetes mellitus (T2DM). However, the role of underlying…
Durgala, Horvath, Skrabanova et al. · 2026 · Frontiers in behavioral neuroscience
Traumatic brain injury (TBI) is a major health concern in the current population. Animal models are increasingly important for identifying early neurobehavioural changes associated with mild to severe as well as repetitive brain injuries.…
Choi, Park, Song et al. · 2026 · Psychiatry investigation
Although its potential antidepressant effects have been suggested, evidence on long-term outcomes for post-delivery depression remains limited. We evaluated whether peripartum intravenous magnesium sulfate (MgSO₄) is associated with…
Lamb, Akulian, Musani et al. · 2026 · Respiratory research
Single chain urokinase (LTI-01) intrapleural enzymatic therapy (IET) was safe and promising in a phase 1 clinical trial to overcome failed drainage in patients with pleural infection. The LTI-01-2001 phase 2a trial was a randomized,…
Akdogan, Aydin · 2026 · BMC oral health
Data comparing the wear of 3D printed permanent resin (PR) and milled zirconia (Z) to that of primary tooth enamel are limited. This study aimed to investigate the wear behavior of two materials and their effect on antagonist primary…
Güler, Kaplan, Şahan et al. · 2026 · Pain management nursing : official journal of the American Society of Pain Management Nurses
Pain during arteriovenous fistula (AVF) catheterization is a common discomfort faced by hemodialysis patients and can negatively affect treatment adherence, satisfaction, and overall quality of life. Effective pain management strategies…
Russo, Comune, Di Nardo et al. · 2026 · International journal of cardiology
The shortened protocol of Nitroglycerin (NTG)-potentiated head-up tilt testing (HUTT), the so-called "fast Italian protocol," has been shown to significantly reduce test duration while maintaining diagnostic yield and safety in adults with…
Yeh, Ahuja, Patel et al. · 2026 · Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
We conducted a target trial emulation study to examine the effect of two glucagon-like peptide-1 receptor agonists (GLP1RAs) (semaglutide and tirzepatide) on clinical outcomes in patients with inflammatory bowel diseases (IBD) with obesity…
Li, Chen, Zhou et al. · 2026 · Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions
Moderate/severe mitral regurgitation (MR) can affect the prognosis of patients with transcatheter aortic valve replacement (TAVR). However, few studies have focused on the role played by papillary muscles (PMs). We intend to explore the…
Bodur, Küçükekenci̇ · 2026 · BMC oral health
This study investigated how different access cavity designs and irrigation solutions influence the removal of calcium hydroxide from root canals. Eighty-four mandibular molars were divided into three groups according to their access…
Zhai, Zhu, Lan et al. · 2026 · Annali italiani di chirurgia
This study aimed to explore the clinical application of surgical methods based on different lung segments and pathological subtypes in the treatment of T1b lung adenocarcinoma. A total of 207 patients with T1b lung adenocarcinoma admitted…
Sun, Gong, Zhu et al. · 2026 · Annali italiani di chirurgia
This study aims to explore the critical risk factors associated with surgical site infection (SSI) in patients with type 2 diabetes mellitus (T2DM) undergoing oral and maxillofacial surgery, and to develop a predictive model to support…
Shu, Jin, Peng · 2026 · Annali italiani di chirurgia
Given the high incidence of postoperative cognitive decline and reduced self-efficacy in lung cancer patients undergoing radical thoracoscopic surgery, this study aimed to investigate the effect of evidence-based nursing combined with…
Kavakli, Bozkurt, Diri et al. · 2026 · Surgical endoscopy
Conventional abdominal wall blocks primarily target somatic afferent nerves and may therefore provide limited relief for the peritoneal component of postoperative pain. This study aimed to investigate whether a laparoscopic-guided deep…
Calkins, Alaei, Winkler et al. · 2026 · Scientific reports
Tendons are essential for force transmission, yet the influence of menstrual cycle phase on upper-limb positional tendon mechanics is unknown. This exploratory study investigated biceps brachii tendon mechanics across the menstrual cycle.…
Nakashima, Iguchi, Sugimoto et al. · 2026 · Clinical nuclear medicine
Chronic lung allograft dysfunction (CLAD) is a major cause of late morbidity after lung transplantation, and spirometry lacks the ability to detect regional lung changes. Thus, in this study, we investigated whether quantitative perfusion…
Muto, Ohtake · 2026 · Journal of occupational and environmental medicine
To evaluate whether nudge emails increased early registration for an occupational health support program among employees advised to act after annual health checkups. In this stratified randomized controlled trial, 871 employees with no…
Jimbih, Mazlan, Waran et al. · 2026 · PloS one
Traumatic brain injury (TBI) resulting from road traffic accidents (RTAs) is a leading cause of morbidity in children globally. However, paediatric TBI outcomes are understudied in Southeast Asia. To examine functional outcomes and…
Kibak, Mouritsen · 2026 · Journal of helminthology
The concept of 'ecology of fear' recognises the importance of non-consumptive effects of predators inspiring fear in their prey, but has subsequently been broadened to include the non-consumptive effects of parasites on their hosts. Here,…
Chiriani, Fiorillo, Song et al. · 2026 · Applied ergonomics
The evolution of autonomous vehicle interiors presents both opportunities and challenges in optimizing space for Non-Driving Related Activities (NDRAs). Previous research explored the reconfiguration of interiors in autonomous vehicles to…
Badi, Yilmaz, Odabasi Tezer et al. · 2026 · European endodontic journal
This study evaluated tooth discolouration potential of triple antibiotic paste (TAP) containing either minocycline or cefuroxime, Ledermix and Odontopaste using spectrophotometric analysis. Sixty extracted human maxillary central incisors…