Negative / Null Result ReportOpen accessVocational rehabilitation. Employment of people with disabilities
Uzair Ahmad, Babar Ali, Seema Gul et al. · 2025 · Journal Riphah College of Rehabilitation Sciences
Background: Regular physical activity has a positive impact on brain function, improves perception, and significantly influences academic achievement. Objective: This study aimed to determine the association of physical activity, motor skills, and academic performance in high school students in Hayatabad, Peshawar. Methodology: A total of 349 students were recruited using stratified random sampling from both public and private high schools within the Hayatabad region, Peshawar, Pakistan from December 2020 to May 2021. Only students in 9th and 10th grades from public and private schools who met
Negative / Null Result ReportOpen accessTherapeutics. Pharmacology
Rudra Paul, Arijit Ghosh, Nilanjan Sengupta et al. · 2022 · National Journal of Physiology, Pharmacy and Pharmacology
Background: Type 2 diabetes mellitus (DM) is mainly due to multifactorial of which insulin resistance and deficiency in the incretion are two important pathophysiological factors. Vildagliptin, an oral hypoglycemic agent, acts by inhibiting dipeptidyl peptidase-4 enzyme, often uses as a first line drug along with metformin to enhance outcome. Aim and Objective: The aim of this study was to compare the effectiveness and safety of vildagliptin 50 mg twice daily dose with vildagliptin 100 mg sustained release tablet (SR) once daily in Type 2 DM patients and uncontrolled with metformin monotherapy
View details →DOI: 10.5455/njppp.2022.12.062851202217862022 Negative / Null Result ReportOpen accessMedicine
Davidović Lazar B., Kuzmanović Ilija B., Kostić Dušan M. et al. · 2002 · Srpski Arhiv za Celokupno Lekarstvo
The infection of the previously implanted vascular graft at the groin, is associated with great mortality and morbidity rate [1]. The authors present a retrospective study in which they analyzed management of infected vascular prostheses at the groin, using obturator bypass in 26 cases, and "lateral" bypass in 15 cases. The indications for obturator bypass reconstructions included: 20 infections of aorto-femoral grafts, two infected pse udoaneurysms in the groin after RTA of the superficial femoral artery, and 4 infections of iliac-femoral grafts. The indications for lateral bypass reconstruct
View details →DOI: 10.2298/sarh0202027d Negative / Null Result ReportOpen accessPhysics
Zihao Qiu, Siyu Chen, Zixin Feng et al. · 2025 · Frontiers in Physics
Futures, as significant financial derivatives, play a crucial role in financial markets by fulfilling price discovery functions and providing efficient risk hedging tools. Against the backdrop of geopolitical conflicts, market risk emerges not only from external shocks and random fluctuations but also from strategic interactions among diverse participants including hedgers, speculators, arbitrageurs, and regulators. This study integrates traditional VaR theory with machine learning methods to systematically examine risk characteristics and transmission mechanisms in the sugar futures market un
View details →DOI: 10.3389/fphy.2025.1674717 Negative / Null Result ReportOpen accessDiseases of the blood and blood-forming organs
NING Li, ZHANG Yanyan, ZENG Jinfeng et al. · 2026 · Zhongguo shuxue zazhi
[Objective] To statistically analyze the association between blood donation intervals and the incidence of adverse reactions to blood donation based on blood donor data from Shenzhen. [Methods] Basic data and records of adverse reactions to blood donation among voluntary whole blood donors in Shenzhen from January 2017 to June 2025 were extracted. A total of 795 404 whole blood donations were recorded, including 502 743 from males and 292 661 from females, with 1 088 and 751 cases of adverse reactions, respectively. Analyses were performed using R software, including restricted cubic spline (R
View details →DOI: 10.13303/j.cjbt.issn.1004-549x.2026.03.006 Negative / Null Result ReportMedicine
Sowinska N, Ochota M, Partyka A et al. · 2026 · Animal reproduction science
The domestic cat (Felis catus) provides a valuable model for developing assisted reproductive technologies (ART) that can be applied to the conservation of endangered wild felids. A major limitation in the application of ART is the…
View details →DOI: 10.1016/j.anireprosci.2026.108147 Negative / Null Result ReportOpen accessMedicine
Molly Moore Jeffery, Lucas Oliveira J e Silva, Fernanda Bellolio et al. · 2022 · BMJ Open
Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The USA; 2017–2018 influenza season, 2018–2019 influenza season, and 2019–2020 influenza/COVID-19 season.Participants People with hypertension (HTN) taking an ACEi, ARB or other HTN medications, and experiencing AVRI.Main outcome measures Change in hospital admission, intensive care unit (ICU) or coronary care unit (CCU), acute respiratory distress (ARD
View details →DOI: 10.1136/bmjopen-2021-060305 Negative / Null Result ReportOpen accessSurgery
Engin Kölükçü, Şahin Kılıç, Doğan Atılgan et al. · 2018 · Journal of Urological Surgery
Objective:The association of preoperative neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) with postoperative tumor stage and Fuhrman nuclear grade was investigated in patients with renal cell carcinoma (RCC).Materials and Methods:Data of 123 patients, who were operated due to RCC, in our clinic was analysed. NLR and PLR were evaluated in patients who were classified according to tumor stage (T1 and T2 low stage, T3 and T4 high stage) and Fuhrman nuclear grade (grade 1 and 2 low-grade, grade 3 and 4 high-grade). NLR and PLR were compared using Levene’s test between t
View details →DOI: 10.4274/jus.2133 Negative / Null Result ReportOpen accessPediatrics
LI Yue, XIE Zhiwei, TANG Yanjing, LI Benshang · 2026 · Linchuang erke zazhi
Objective Antigen escape, particularly CD19 loss, limits the efficacy of CD19-targeted chimeric antigen receptor T-cell (CAR-T) therapy in children with relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL). PAX5 gene variations have been shown to disrupt CD19 expression stability and increase relapse risk. This study aimed to compare the therapeutic efficacy of two CD19/CD22 dual-targeting CAR-T strategies, namely co-infusion versus bicistronic construct, in children with R/R B-ALL harboring PAX5 gene variations. Methods A retrospective analysis was conducted on the clinical dat
View details →DOI: 10.12372/jcp.2026.26e0038 Negative / Null Result ReportOpen accessDentistry
Mohammad Tavakoli, Ensiyeh Bateni, Mansour Rismanchian et al. · 2012 · Dental Research Journal
Background: The greater surface of bioactive glass nanoparticles presents an incomparable and promising feature similar to the biological apatite. Nanoparticles improve cellular adhesion, enhance osteoblast proliferation and differentiation, and increase biomineralization for periodontal regeneration and dental implants. Considering the fact that interaction between periodontal cells and bone graft materials are important for periodontal lesion regeneration, the present study was undertaken to investigate the genotoxicity of a novel synthesized nanoscale bioactive glass and compared it with No
View details →DOI: 10.4103/1735-3327.99831 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Pedro Davila-Piñón, Pedro Davila-Piñón, Alba Nogueira-Rodríguez et al. · 2024 · Frontiers in Oncology
BackgroundPolyDeep is a computer-aided detection and classification (CADe/x) system trained to detect and classify polyps. During colonoscopy, CADe/x systems help endoscopists to predict the histology of colonic lesions.ObjectiveTo compare the diagnostic performance of PolyDeep and expert endoscopists for the optical diagnosis of colorectal polyps on still images.MethodsPolyDeep Image Classification (PIC) is an in vitro diagnostic test study. The PIC database contains NBI images of 491 colorectal polyps with histological diagnosis. We evaluated the diagnostic performance of PolyDeep and four e
View details →DOI: 10.3389/fonc.2024.1393815 Negative / Null Result ReportOpen accessMedicine
Lara Kakabas, Krzysztof Piersiala, Aeneas Kolev et al. · 2023 · Scientific Reports
Abstract A history of allergies has been said to be associated with a lower risk of head and neck cancer compared to the general population. However, it is not known whether having an allergic sensitization influences the prognosis and advancement of cancer disease. Thus, the aim of the study was to investigate the relationship between allergic sensitization and oral cancer advancement and patient survival. Allergen-specific IgE antibodies were investigated by ImmunoCAP™ Rapid in consecutive 80 patients with oral cancer. ImmunoCAP Rapid system tests a mix of representative inhalant allergens s
View details →DOI: 10.1038/s41598-023-48879-8 Negative / Null Result Report
Chebe PC, Martens K · 2026 · Preprint
Abstract The construct of sense of place (SoP) has gained growing interdisciplinary attention for its ability to capture the intricate relationship between people and their environments, a key consideration in urban planning. Despite this…
View details →DOI: 10.21203/rs.3.rs-9766699/v1 Negative / Null Result ReportOpen accessMedicine
Alberta Simona Tinu, Doina Lucia Ghergic, Mirel Stoian et al. · 2018 · Romanian Journal of Stomatology
Objectives. We performed a retrospective observational analytical study to determine the incidence of complications in the oral cavity in a group of patients diagnosed with diabetes mellitus. Material and method. We have studied 68 diabetic patients, who have been referred to dental practices seeking specialized treatment. Patient data sheets were centralized, categorized, and statistically processed with IBM SPSS Statistics 22 and Microsoft Excel 2010 depending on: sex of patients, age, type of diabetes, time elapsed from diagnosis of diabetes, the environment of origin of the patients, the l
View details →DOI: 10.37897/rjs.2018.1.1 Negative / Null Result ReportOpen accessMedicine
Yunsur Çevik, Fatma Nur Karaarslan, Şeref Kerem Çorbacıoğlu et al. · 2022 · Eurasian Journal of Emergency Medicine
Aim:The aim of this study was to examine the relationship between immature granulocyte (IG) counts and the severity of the disease and to evaluate the effectiveness of IG in predicting the poor outcomes in polymerase chain reaction-confirmed Coronavirus disease-2019 (COVID-19) cases.Materials and Methods:The study was conducted prospectively and observationally at the emergency department. Patients were divided into three groups according to the clinical severity indicators such as mild, moderate and severe. The IG level was measured from the whole blood samples taken at the admission to the e
View details →DOI: 10.4274/eajem.galenos.2021.79836 Negative / Null Result ReportOpen accessMedicine
Rasa Liutkevičienė, Ramunė Sungailienė, Alvita Vilkevičiūtė et al. · 2017 · Acta Medica Lituanica
Background. Age-related macular degeneration (AMD) is the most common cause of irreversible visual loss in industrialized countries. Early symptoms of AMD include drusen and changes in retinal pigment epithelium. However, the etiology of AMD and drusen formation is not fully understood. Recent studies suggest that CYP2C8-related metabolic processes might play an important role in the development of AMD. The aim of our study is to investigate CYP2C8 rs10509681 and CYP2C8 rs11572080 genotype frequencies in patients with early AMD and to compare them with healthy controls. Materials and Methods.
View details →DOI: 10.6001/actamedica.v24i2.3487 Negative / Null Result ReportOpen accessDiseases of the digestive system. Gastroenterology
Hao Lu, Shikuan Li, Chengzhi Wang et al. · 2025 · BMC Gastroenterology
Abstract Objective To investigate the impact of peritoneal lavage on the incidence of intra-abdominal abscess (IAA) after laparoscopic appendectomy (LA) in adults with perforated appendicitis. Methods Clinical data from adult patients intraoperatively diagnosed with perforated appendicitis and undergoing LA at the Affiliated Hospital of Qingdao University between January 2020 and January 2025 were retrospectively analyzed. Patients were divided into a no-peritoneal lavage group and a peritoneal lavage group based on whether peritoneal lavage was performed. A total of 128 patients were included
View details →DOI: 10.1186/s12876-025-04397-7 Negative / Null Result ReportOpen accessMedicine (General)
Maria Aparecida A.O. Serra, PhD, Arlene T. Medeiros, RN, Mateus D. Torres, RN et al. · 2021 · Journal of Taibah University Medical Sciences
الملخص: أهداف البحث: الأعراض الهضمية هي الشكاوى الأكثر شيوعا من قبل المرضى الذين يسعون للحصول على خدمات الرعاية الصحية الأولية. تهدف هذه الدراسة إلى تحديد أعراض الجهاز الهضمي وتحديد ارتباطها بنتائج التنظير المعوي العلوي لدى المرضى الذين عولجوا في مركز التنظير العام في شمال شرق البرازيل. طرق البحث: أجرينا دراسة مقطعية باستخدام بيانات ٧٥١ مريضا يعانون من أعراض الجهاز الهضمي ولديهم حاجة للتنظير المعوي العلوي. حددنا الارتباط بين هذه المتغيرات من خلال اختبار فيشر الدقيق وحسبنا نسبة الاحتمالات. النتائج: أظهرت النتائج أن ٨٣٪ من المرضى يعانون من آلام شرسوفية، ٧٢.٦٪ من الامتلاء بعد الأكل، و٧٢.٣٪ من حرق
View details →DOI: 10.1016/j.jtumed.2020.12.020 Negative / Null Result ReportOpen accessDermatology
Imran Majid, Gousia Sheikh, Farhath Kanth et al. · 2016 · Indian Journal of Dermatology
Background: The incidence of recurrent tinea infections after oral terbinafine therapy is on the rise. Aim: This study aims to identify the appearance of incomplete cure and relapse after 2-week oral terbinafine therapy in tinea corporis and/or tinea cruris. Materials and Methods: A total of 100 consecutive patients clinically and mycologically diagnosed to have tinea corporis and/or tinea cruris were included in the study. The enrolled patients were administered oral terbinafine 250 mg once daily for 2 weeks. All clinically cured patients were then followed up for 12 weeks to look for any rel
View details →DOI: 10.4103/0019-5154.190120 Negative / Null Result ReportOpen accessMedicine
Damkoeng Purnindu · 2023 · Siriraj Medical Journal
Dissection of one-half of adult pelvis in 197 Thai and 44 Chinese cadavers disclosed that the obturator artery arose from the internal iliac and umbilical arteries in 34.9%, from the inferior gluteal artery in 10.4%, from the internal pudendal artery in 8.7%, from the superior gluteal - inferior gluteal trunk in 4.2%, from the inferior gluteal - internal pudendal trunk in 9.1%, from the inferior epigastric artery in 12.0%, from the external iliac artery in 1.2%, and from the superior gluteal and the inferior epigastric arteries in 0.4%. There were no statistically significant differences of fi
Negative / Null Result ReportOpen accessAnesthesiology
Orhan Kılıç, Murat Yaşar Özkalkanlı, Fulya Yılmaz et al. · 2022 · Ain Shams Journal of Anesthesiology
Abstract Background Malnutrition is an important and widespread problem in hospitalised elderly orthopaedic patients. It is an important predictor of morbidity and mortality and has been associated with an increased risk of complications. Although it is a common problem in the elderly, there is neither a universally accepted criterion for the diagnosis of malnutrition nor a screening tool accepted as the gold standard to detect patients at risk of malnutrition. There is still no consensus on which is the most recommended for screening hospitalised patients for nutritional risk. The aim of this
View details →DOI: 10.1186/s42077-022-00280-9 Negative / Null Result ReportOpen accessDentistry
Deece Patuti, Harmas Yazid Yusuf, Bethy Suryawathy Hernowo · 2010 · Padjadjaran Journal of Dentistry
Introduction: CD10 can also facilitate the ability of tumour metastasis by its ability to invade blood vessel walls.Correlation of CD10 immunoexpression and eosinophil count in stromal tissue as predictors of prognosis of squamous cell carcinoma of the oral cavity. Methods: This study was preceded by collecting data on squamous cell carcinoma of the oral cavity in the medical record and paraffin blocks in the Anatomy Pathology section of 15 samples with enlarged regional lymph nodes and 15 samples without enlargement of regional lymph nodes. Then two preparations were made, the first preparati
View details →DOI: 10.24198/pjd.vol22no2.26873 Negative / Null Result ReportOpen accessMedicine
Tasić Danijela, Kovačević Zorana, Mitrović Miroslav et al. · 2021 · Scripta Medica
Background/Aim: Orthostatic hypotension (OH) is considered to be a drop in the systolic and diastolic blood pressure (> 20 mmHg; > 10 mmHg) 3 minutes from postural changes. The objective of this study was to analyse the correlation of body mass index (BMI) and OH during the treatment with trandolapril, as a single-drug treatment of hypertension. Methods: The study involved 255 patients (average age 54.3 ± 11.7; 54.1 % men) with poorly regulated hypertension, who were given trandolapril as a single-drug treatment. The patients were divided into two groups regarding stage of hypertension: first-
View details →DOI: 10.5937/scriptamed52-32561 Negative / Null Result ReportOpen accessMedicine
Hall, Natalie J, Berry, Sameer K, Aguilar, Jack et al. · 2021 · JMIR Formative Research
BackgroundA potential benefit of electronic health records (EHRs) is that they could potentially save clinician time and improve documentation by auto-generating the history of present illness (HPI) in partnership with patients prior to the clinic visit. We developed an online patient portal called AEGIS (Automated Evaluation of Gastrointestinal [GI] Symptoms) that systematically collects patient GI symptom information and then transforms the data into a narrative HPI that is available for physicians to review in the EHR prior to seeing the patient. ObjectiveThis study aimed to compare whether
View details →DOI: 10.2196/23599 Negative / Null Result ReportOpen accessDiseases of the genitourinary system. Urology
Dursun Baba, Necati Ekici, Arda Taşkın Taşkıran et al. · 2025 · BMC Urology
Abstract Background Urinary stone disease is a common urological disorder, particularly among middle-aged individuals. Extracorporeal Shock Wave Lithotripsy (ESWL) is often the first-line treatment for kidney and ureteral stones. Traditionally, fluoroscopy is used for stone targeting in ESWL, but it exposes patients and clinicians to radiation and cannot visualize non-opaque stones. Ultrasonographic targeting eliminates these issues. This study compares the advantages and disadvantages of fluoroscopy and ultrasound-targeted ESWL. Methods At Düzce University Hospital, 100 patients with radio-op
View details →DOI: 10.1186/s12894-025-01716-8 Negative / Null Result ReportOpen accessMicrobiology
Bakori, H. S., Kumurya, A. S., Idris, A. M. · 2024 · UMYU Journal of Microbiology Research
Mycoplasma genitalium is an emerging sexually transmitted pathogen with potential implications for reproductive health. This study aimed to investigate and compare the seroprevalence of M. genitalium among fertile and infertile women to provide insights into its potential association with fertility outcomes. A cross-sectional study was conducted involving a total of 90 women, including 31 fertile and 59 infertile women. Serum samples were collected and tested for the presence of M. genitalium-IgG antibodies using ELISA detection techniques. Data on demographic characteristics, including age an
View details →DOI: 10.47430/ujmr.2492.014 Negative / Null Result ReportOpen accessSurgery
Taner İyigun, Mugisha Kyaruzi, Barış Timur et al. · 2019 · Turkish Journal of Vascular Surgery
Objectives: This study aims to compare midterm results of patch angioplasty with primary closure techniques in patients undergoing carotid endarterectomy (CEA) in terms of restenosis. Patients and methods: This prospective, single-center, randomized study included a total of 137 patients (42 females, 95 males; mean age 64.4±8.8 years; range 36 to 86 years) who underwent CEA between January 2010 and October 2015. The patients were divided into two groups: the patch angioplasty group (n=70) and the primary closure group (n=67). The mean follow-up was 2-7 years. Carotid computed tomography angiog
Negative / Null Result ReportOpen accessMedical technology
Simon Marchant, Shona Michael, Laura Milner et al. · 2019 · Journal of Rehabilitation and Assistive Technologies Engineering
Introduction Functional electrical stimulation uses clinician-set parameters to modify stimulation. This study aimed to investigate whether timing parameters in the ODFS Pace functional electrical stimulation device have an effect on the gait of the general population of functional electrical stimulation users who have a foot drop. Methods Twelve functional electrical stimulation users with foot drop resulting from upper motor neurone disorders were recruited from the functional electrical stimulation Service in Leeds, UK. A crossover trial design was used, comparing adjusted values of rising
View details →DOI: 10.1177/2055668319859142 Negative / Null Result ReportOpen accessEducation
ولاء أحمد عباس مرسى · 2018 · تکنولوجیا التعلیم: سلسلة دراسات و بحوث
هدف البحث إلى تحديد انسب نمط لبيئة التعلم المقلوب (تدريس الأقران مقابل الاستقصائي) في إطار تفاعله مع استراتيجية التنظيم الذاتي للتعلم (البحث عن المساعدة مقابل البحث عن المعلومات)، ودراسة مدى تأثيرها في تنمية التحصيل الفوري والمرجأ، ودافعية الإنجاز، والرضا عن بيئة التعلم لدى طلاب تکنولوجيا التعليم. وقد استخدم في هذا البحث التصميم التجريبي ذي المجموعات التجريبية الأربعة، وهو امتداد للتصميم التجريبي ذي المجموعة الواحدة، واشتمل البحث على متغير مستقل وله مستويان: بيئة التعلم المقلوب (تدريس الأقران مقابل الاستقصائي)، مع استراتيجية التنظيم الذاتي للتعلم (البحث عن المساعدة مقابل البحث عن المعلومات)، و
View details →DOI: 10.21608/tesr.2018.124659 Negative / Null Result ReportOpen accessSurgery
Amber M. Parker, MD, Nicholas Genovese, MD, Alexy Ilchuk, BS et al. · 2026 · Journal of Hand Surgery Global Online
Purpose: To assess and compare the associative value of comorbidity fracture-specific index (CFI) versus the Charlson comorbidity index (CCI) in identifying patients at risk for early complications after open reduction and internal fixation (ORIF) of distal radius fractures (DRFs). Methods: We performed a single-center retrospective cohort study including patients ≥40 years who underwent ORIF for closed DRF using a volar locking plate with a minimum of 1 year follow-up. CCI and CFI scores were calculated based on comorbidities over the prior 15 years. The primary outcome was 90-day postoperati
View details →DOI: 10.1016/j.jhsg.2026.100959 