Negative / Null Result ReportOpen accessMedicine
Hayat F, Chiu S, Stuart A et al. · 2025 · Journal of gastrointestinal oncology
Background Tobacco smoking accounts for 22% of the pancreatic cancer burden in Australia. Smoking may increase therapy-related adverse effects and was associated with shorter survival in the previous analysis of all stages of pancreatic…
View details →DOI: 10.21037/jgo-2025-186 Negative / Null Result ReportOpen accessMedicine
Gu L, Lin J, Yue J et al. · 2025 · Journal of inflammation research
Janus kinase (JAK) inhibitors, developed for autoimmune diseases, have been repurposed as potential therapies for severe COVID-19. Growing evidence indicates that their clinical utility is heterogeneous and cannot be generalized as a class…
View details →DOI: 10.2147/jir.s554898 Negative / Null Result ReportMedicine
Jain H, Zakieh O, Chanbour H et al. · 2025 · Clinical neurology and neurosurgery
Introduction Coronal malalignment (CM) remains an understudied and challenging problem in adult spinal deformity (ASD) surgery, and the impact of the lumbosacral fractional curve (LSF) correction on postoperative outcomes remains poorly…
View details →DOI: 10.1016/j.clineuro.2025.109152 Negative / Null Result ReportMedicine
Gkini E, Mehta RL, Tearne S et al. · 2025 · COPD
Rationale The Predict&Prevent trial was designed to provide a definitive randomised clinical trial of a personalised early warning decision support system, COPDPredict™. Methods Adults with ≥1 AECOPD were randomly assigned in a 1:1 ratio…
View details →DOI: 10.1080/15412555.2025.2544719 Negative / Null Result Report
Askarian-Amiri S, Weissenhorn W, Sadoul R et al. · 2025 · Preprint
Extracellular vesicles (EVs), including exosomes, are widely believed to mediate intercellular communication by delivering molecular cargo to recipient cells. However, the efficiency and mechanisms of such cargo delivery remain unclear. In…
View details →DOI: 10.1101/2025.04.01.646561 Negative / Null Result ReportMedicine
Manolitsis I, Feretzakis G, Tzelves L et al. · 2025 · Studies in health technology and informatics
The ASCAPE project aims to improve the health-related quality of life of prostate cancer patients using artificial intelligence-driven solutions. This study tries to unravel the complex relationships between patient data variables and…
View details →DOI: 10.3233/shti250634 Negative / Null Result ReportMedicine
Heck MM, Lehmann J, Amiel T et al. · 2025 · European urology
The extent of lymph node dissection (LND) at the time of radical cystectomy (RC) for bladder cancer (BC) may affect oncologic outcomes. We present updated long-term data from a prospective, multicenter, phase 3 trial involving patients…
View details →DOI: 10.1016/j.eururo.2025.09.001 Negative / Null Result ReportOpen accessMedicine
Helk O, Wagner L, Sengölge G et al. · 2026 · Diagnostics (Basel, Switzerland)
Background/Objectives: Kidney injury is a frequent complication of multiple myeloma (MM) and monoclonal gammopathies. Podocyte stress markers, such as urinary nephrin and podocin, have been studied in other renal diseases but their utility…
View details →DOI: 10.3390/diagnostics16060922 Negative / Null Result ReportMedicine
Zivkovic Habibi L, Zaibat M, Frenkiel J et al. · 2025 · Soins. Gerontologie
Day care centers are medical and social facilities that provide day care for people over 60 with Alzheimer's or related diseases. The main aim of the study presented here was to assess the impact of horticultural therapy sessions on the…
View details →DOI: 10.1016/j.sger.2024.10.008 Negative / Null Result ReportMedicine
Osama G, Elhilali H, Salah M et al. · 2025 · Strabismus
Purpose To compare the efficacy of two methods: first, bilateral symmetric anteriorization of the inferior oblique muscle and second: combined resection and anteriorization of the inferior oblique (IO) muscle for asymmetric dissociated…
View details →DOI: 10.1080/09273972.2024.2402925 Negative / Null Result ReportMedicine
Sadeghinia A, Emadi SN, Jamshidi S et al. · 2025 · Lasers in medical science
Background Despite extensive research, there is still no consensus on the optimal treatment for Striae distensae (SD). Aim To evaluate the efficacy of ablative (short pulse (SP) mode) versus combined ablative and non-ablative (short pulse…
View details →DOI: 10.1007/s10103-025-04488-7 Negative / Null Result ReportOpen accessMedicine
Dubin A · 2025 · Annals of intensive care
Background Fluids are a key component of shock resuscitation. Nevertheless, their microvascular effects are complex. In fluid responsive patients, fluids may increase tissue perfusion because of the increase in cardiac output. Since shock…
View details →DOI: 10.1186/s13613-025-01607-z Negative / Null Result ReportMedicine
Wregg JF, Hofer A, Gruber-Wackernagel A et al. · 2026 · Experimental dermatology
Water-filtered infrared-A (wIRA) has been proposed to enhance tissue perfusion and modulate fibrosis, but clinical evidence in morphea (localised scleroderma) is limited. We conducted a prospective, intra-individual pilot split-study in 10…
View details →DOI: 10.1111/exd.70273 Negative / Null Result Report
Cradeur A, Abshire M, Schichtel M et al. · 2025 · Preprint
Objectives: This prospective study aimed to assess noise levels in otolaryngology operating rooms (OR), explore noise variation across subspecialties, and examine the correlation between noise, verbal communication, and surgery complexity.…
View details →DOI: 10.20944/preprints202512.0871.v1 Negative / Null Result ReportMedicine
Acikgoz NB, Toplu-Hocaoglu A, Yildirim BA et al. · 2026 · Epilepsy research
Purpose The ketogenic diet has long been used in epilepsy treatment, particularly in drug-resistant cases, but its efficacy in idiopathic generalized epilepsy, including absence epilepsy, remains less studied. This study aimed to evaluate…
View details →DOI: 10.1016/j.eplepsyres.2026.107847 Negative / Null Result Report
SAW YH, CHAI HI, YAHYA NA et al. · 2026 · Preprint
Abstract Background Energy drinks are widely consumed acidic beverages that may compromise the longevity of resin composite restorations. However, limited evidence exists regarding the use of swept-source optical coherence tomography…
View details →DOI: 10.21203/rs.3.rs-9770016/v1 Negative / Null Result Report
Pettenuzzo T, Sella N, Zarantonello F et al. · 2026 · Preprint
Abstract Background. High-flow nasal cannula (HFNC) is a promising respiratory support modality that improves oxygenation, alveolar recruitment, and comfort while reducing dead space compared to conventional oxygen therapy. Recently, a…
View details →DOI: 10.21203/rs.3.rs-8496018/v1 Negative / Null Result ReportMedicine
Dağlı E, Çapar ÖF, Sert S · 2026 · Scientific reports
This study examines the effects of freeze-thaw (F-T) cycles on the unconfined compressive strength (UCS) of untreated and stabilized soils using fly ash, lime, and lime-fly ash mixtures (30% FA, 5% L, and 30% FA + 5% L). Specimens were…
View details →DOI: 10.1038/s41598-026-52479-7 Negative / Null Result ReportOpen accessMedicine
Ryou S, Jung Y, Kim DS et al. · 2026 · The Korean journal of internal medicine
Background/aims Few studies have compared modified endoscopic mucosal resection (EMR) techniques for small rectal neuroendocrine tumors (NETs). This study evaluated the clinical outcomes of ligation-assisted EMR (EMR-L) and precutting EMR…
View details →DOI: 10.3904/kjim.2025.234 Negative / Null Result ReportMedicine
Liu L, Shen Y, Yang S et al. · 2026 · Journal of biotechnology
As an enzyme cofactor, antioxidant, and stabilizer of cellular structures, Mn²⁺is essential for microbial growth, metabolism, and environmental adaptation. In this work, the impact of varying Mn²⁺ levels on caproic acid formation and…
View details →DOI: 10.1016/j.jbiotec.2026.04.025 Negative / Null Result ReportMedicine
Yilmaz AB, Karimzada K, Ozercan AY et al. · 2025 · Journal of robotic surgery
To evaluate the predictive value of the Estimation of Physiologic Ability and Surgical Stress (E-PASS) score, Comorbidity Score for Robotic Surgery (CRS) and Charlson Comorbidity Index (CCI) in relation to postoperative complications in…
View details →DOI: 10.1007/s11701-025-02406-1 Negative / Null Result ReportOpen accessMedicine
Marshall MJ, Peck K, Hunter R et al. · 2024 · Behavioral sciences (Basel, Switzerland)
Eysenck's biopsychological model of stress posits that the extraversion-introversion distinction is associated with different thresholds of arousal, which in turn moderate the stress response. Although higher thresholds of activation have…
View details →DOI: 10.3390/bs14111098 Negative / Null Result Report
Gow J, Roofeh D · 2025 · Preprint
Abstract Background: Giant cell arteritis (GCA) is a large vessel vasculitis characterized by granulomatous inflammation classically affecting the carotid artery branches. GCA most often presents with one or more classic clinical features…
View details →DOI: 10.21203/rs.3.rs-5860997/v1 Negative / Null Result ReportMedicine
Graf J, Buder A · 2025 · Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
Primary erythrocytosis, also known as polycythemia vera, is a myoproliferative disease resulting in an increased red blood cell mass and is associated with increased hematocrit and hemoglobin concentrations. Patients have an augmented risk…
View details →DOI: 10.1055/a-2471-6729 Negative / Null Result ReportMedicine
Khalifa H, Ayaty M, Oreaba R et al. · 2025 · Journal of the Egyptian National Cancer Institute
Objectives Following external beam radiation therapy (EBRT) with concurrent chemotherapy, we analyzed the benefits of surgical resection for locally advanced cervical carcinoma in terms of the frequency and severity of complications and…
View details →DOI: 10.1186/s43046-025-00292-0 Negative / Null Result ReportMedicine
Lyu HH, Wen X, Lin JT et al. · 2025 · Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
Objective: To compare the Kadish T staging, AJCC T staging, and Dulguerov T staging system in terms of their impact on surgical treatment selection and survival prognosis in patients with olfactory neuroblastoma (ONB). Methods: The cases…
View details →DOI: 10.3760/cma.j.cn115330-20240723-00438 Negative / Null Result ReportMedicine
Chen PY, Young TC, Lin CY et al. · 2025 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Objective To determine the hearing outcomes in patients with sudden sensorineural hearing loss (SSNHL) after exposure to different brands of vaccines against COVID-19. Study design Cohort study. Setting Tertiary referral center. Patients…
View details →DOI: 10.1097/mao.0000000000004509 Negative / Null Result ReportMedicine
Zheng X, Zhang T, Zhan T et al. · 2025 · Respiratory medicine
Purpose Positive end-expiratory pressure (PEEP) refers to a vital respiratory therapeutic tool for treating ARDS. Since overweight individuals face a greater risk of pulmonary complications than others, this study aims to assess whether…
View details →DOI: 10.1016/j.rmed.2025.108093 Negative / Null Result ReportMedicine
Syed-Abdul MM, Tian L, Hegele RA et al. · 2025 · The lancet. Diabetes & endocrinology
There is a well-established link between the severity of hypertriglyceridaemia and acute pancreatitis and long-term triglyceride-lowering therapies known to prevent episodes of acute pancreatitis. Therefore, it has been assumed, without…
View details →DOI: 10.1016/s2213-8587(25)00028-2 Negative / Null Result ReportMedicine
Pina L, Eufemio CM, Dove J et al. · 2025 · Surgical endoscopy
Introduction Laparoscopic Sleeve Gastrectomy (LSG) and Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) constitute the most commonly performed bariatric metabolic surgery (BMS) procedures in the USA. The number of robotic-assisted BMS cases…
View details →DOI: 10.1007/s00464-025-11719-z 