Negative / Null Result ReportMedicine
Ma, Wei, Cai et al. · 2026 · IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
Virtual try-on (VTON) aims to synthesize specific fashion images dressed in given garments, which possesses great potential in real-world scenarios. Existing methods generally stand on the shoulder of the single-view VTON to train a…
View details →DOI: 10.1109/tip.2026.3700904 Negative / Null Result ReportMedicine
Gyurina, Radványi, Sasi-Szabó et al. · 2026 · Cells
Catecholamines are crucial signaling molecules that initiate thermogenesis in adipocytes through beta-adrenergic receptors (ADRBs). Adipocyte catecholamine resistance is a common feature of pediatric obesity, often impeding weight loss and…
View details →DOI: 10.3390/cells15111000 Negative / Null Result ReportMedicine
Hsiao, Lai, Chen et al. · 2026 · The journal of headache and pain
Objective and interpretable brain signatures for migraine diagnosis and phenotyping remain limited. Edge-centric connectivity treats interregional connections as primary analytical units and captures higher-order, frequency-resolved…
View details →DOI: 10.1186/s10194-026-02420-0 Negative / Null Result ReportMedicine
Kang, Kim, Kim et al. · 2026 · Experimental & molecular medicine
Inducible T cell costimulator (ICOS) signalling is essential for follicular helper T (Tfh) cell activation and has emerged as a therapeutic target in B cell-dependent autoimmune diseases such as systemic lupus erythematosus (SLE). However,…
View details →DOI: 10.1038/s12276-026-01756-6 Negative / Null Result ReportMedicine
Li, Zhang, Leng et al. · 2026 · IEEE journal of biomedical and health informatics
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder that requires early and efficient diagnosis. Functional magnetic resonance imaging (fMRI), with high temporal and spatial resolution, is a powerful tool for…
View details →DOI: 10.1109/jbhi.2026.3702096 Negative / Null Result ReportMedicine
Liao, Xiang, Chen et al. · 2026 · PloS one
The neutrophil-to-lymphocyte ratio (NLR) has shown inconsistent prognostic value in individuals with sepsis. This study aimed to clarify its ability to predict 28-day mortality via a machine learning-based analysis of a large ICU database.…
View details →DOI: 10.1371/journal.pone.0348676 Negative / Null Result ReportMedicine
Ippoliti, Gori, Coscarella et al. · 2026 · Skin health and disease
Abrocitinib, a selective Janus kinase 1 (JAK1) inhibitor, has demonstrated efficacy in moderate-to-severe atopic dermatitis (AD), although data in patients whose AD is resistant to multiple systemic therapies remain limited. We report the…
View details →DOI: 10.1093/skinhd/vzag045 Negative / Null Result ReportMedicine
Puppala, Chodavarapu, Sami et al. · 2026 · Indian journal of orthopaedics
Femoral head impaction injuries, sometimes referred to as the "Hill-Sachs lesion" of the femoral head, are an uncommon yet significant consequence of posterior hip dislocations. These occur due to compressive forces on the femoral head,…
View details →DOI: 10.1007/s43465-025-01572-6 Negative / Null Result ReportMedicine
Gan, Abu Hassan, Tan et al. · 2026 · Therapeutic advances in neurological disorders
Acute attacks of aquaporin-4 antibody neuromyelitis optica spectrum disorder (AQP4-Ab NMOSD) are typically managed with intravenous methylprednisolone, with therapeutic plasma exchange (PLEX) reserved for severe episodes. Despite these…
View details →DOI: 10.1177/17562864261449515 Negative / Null Result ReportMedicine
Bedia Cadelo, García Feijoo, Zamorano-Fernandez et al. · 2026 · BMJ case reports
A boy in his early teens presented with transient visual disturbances and headache. Brain imaging revealed bilateral occipital infarctions, while vascular studies demonstrated bilateral V3 vertebral artery wall abnormalities with…
View details →DOI: 10.1136/bcr-2026-272989 Negative / Null Result ReportMedicine
Dong, Patel, Wang et al. · 2026 · Environment international
Phthalates are pervasive endocrine-disrupting chemicals widely used in consumer products. The wide use of many phthalates results in chronic human exposure to complex mixtures rather than single compounds. Despite extensive studies on…
View details →DOI: 10.1016/j.envint.2026.110332 Negative / Null Result ReportMedicine
Malzahn, Höft Budde, Kneißl et al. · 2026 · Innere Medizin (Heidelberg, Germany)
The German healthcare system, despite its high performance, fails to achieve the goal of needs-based service provision. Supply-induced demand, regional disparities and misaligned financial incentives lead to overuse, underuse and misuse of…
View details →DOI: 10.1007/s00108-026-02117-1 Negative / Null Result ReportMedicine
Faurholt-Jepsen, Hammershøi, Bruun et al. · 2026 · Journal of affective disorders
Distinguishing between bipolar disorder type I and II constitutes a significant clinical challenge that relies on retrospective patient recall. Misclassification carries risks of inappropriate pharmacological management. Digital…
View details →DOI: 10.1016/j.jad.2026.122027 Negative / Null Result ReportMedicine
He, Lin, Zhang et al. · 2026 · Diabetes research and clinical practice
Cardiovascular-kidney-metabolic (CKM) syndrome defines a pathophysiological continuum linking obesity, metabolic dysfunction, chronic kidney disease, and cardiovascular disease. Stages 0-3 represent a critical subclinical window for…
View details →DOI: 10.1016/j.diabres.2026.113336 Negative / Null Result ReportMedicine
Romero-Alfano, Prats, Raldúa et al. · 2026 · The Science of the total environment
Mixture toxicity studies on neuroactive chemicals remain scarce and often rely on simplified combinations of compounds with known modes of action (MoA), despite the frequent non-monotonicity of neuroactive responses. Furthermore, real…
View details →DOI: 10.1016/j.scitotenv.2026.181901 Negative / Null Result ReportMedicine
Lin, Li, Cheng et al. · 2026 · Briefings in bioinformatics
Current metabolomics approaches predominantly rely on group-level differential abundance screening. While effective for identifying biomarkers, this paradigm often overlooks upstream regulatory hubs and fails to resolve the…
View details →DOI: 10.1093/bib/bbag264 Negative / Null Result ReportMedicine
Oduncu, Zor, Çimen et al. · 2026 · Forensic science, medicine, and pathology
Gunshot wounds (GSW) pose serious risks to both mother and fetus. Determining the trajectory and cause of death in the fetus in GSW is of forensic importance. This study aims to contribute to the literature with two rare GSW cases leading…
View details →DOI: 10.1007/s12024-026-01271-0 Negative / Null Result ReportMedicine
Lu, Wang, Chen et al. · 2026 · Cell death discovery
Proper oocyte maturation is critical for female fertility, yet whether cuproptosis, a recently identified copper-dependent cell death pathway, affects meiotic maturation remains unknown. Here, we show that Cu(II)-elesclomol (ELC-Cu(II))…
View details →DOI: 10.1038/s41420-026-03168-x Negative / Null Result ReportMedicine
Walther, Hänel, Krohn et al. · 2026 · International journal of sports physiology and performance
To compare effects of block periodization against evenly distributed low-intensity training on endurance performance in well-trained junior cross-country (XC) skiers. Twenty junior cross-country skiers participated in a crossover design…
View details →DOI: 10.1123/ijspp.2025-0552 Negative / Null Result ReportMedicine
Gu, Wen, Liu et al. · 2026 · Circulation
Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high mortality. Dysregulation of intracellular ion (ie, Na + /H + and Ca 2 + ) cycling underlies reduced cardiac contractility. The…
View details →DOI: 10.1161/circulationaha.126.079823 Negative / Null Result ReportMedicine
Srimanan, Sawangsribanterng, Poolsawat et al. · 2026 · Cureus
Internuclear ophthalmoplegia (INO) is a classic neuro-ophthalmologic syndrome caused by disruption of the medial longitudinal fasciculus (MLF), resulting in impaired adduction of the affected eye and abducting nystagmus of the…
View details →DOI: 10.7759/cureus.107359 Negative / Null Result ReportMedicine
Patel, Patel · 2026 · Cureus
Chronic pain is a complex phenomenon whose assessment involves not only physiological but also psychological and social components. Due to its subjective and variable nature, accurately measuring chronic pain remains challenging in both…
View details →DOI: 10.7759/cureus.109593 Negative / Null Result ReportMedicine
Songthap, Wanaratwichit, Mekrungrongwong · 2026 · BMC public health
Despite existing efforts, premarital sex among Thai adolescents remains a critical public health concern, exacerbated by nearly universal smartphone access and prolonged daily digital exposure. Traditional surveillance often fails to…
View details →DOI: 10.1186/s12889-026-27807-1 Negative / Null Result ReportMedicine
Cruciani, Cafaro, Perricone et al. · 2026 · Clinical and experimental rheumatology
This study aimed to compare different treatment strategies for rheumatoid arthritis (RA) patients following inadequate response to initial methotrexate (MTX) therapy, evaluating clinical outcomes, tolerability profiles, and factors…
View details →DOI: 10.55563/clinexprheumatol/zssu99 Negative / Null Result ReportMedicine
Zhang, Wei, Wu et al. · 2026 · Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Alcohol-associated liver disease (ALD) progresses from steatosis to steatohepatitis, but the underlying mechanisms remain unclear. Here, we investigated SETDB1's role in ALD progression involving LC3B-mediated LC3-associated phagocytosis…
View details →DOI: 10.1002/advs.202513189 Negative / Null Result ReportMedicine
Bonglack, Carrel-Lammert, Hoehn et al. · 2026 · Urogynecology (Philadelphia, Pa.)
Acute urinary tract infections (UTIs) are common after prolapse and anti-incontinence surgery, with incidence rates varying from 14% to 64%. The objective was to decrease rates of symptomatic urinary tract infections in patients undergoing…
View details →DOI: 10.1097/spv.0000000000001742 Negative / Null Result ReportMedicine
Mizuno, Chretien, Nishida et al. · 2026 · Journal of gastroenterology
Immune checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs), including cholangitis, a rare but clinically severe hepatobiliary phenotype. Whether potassium-competitive acid blockers (PCABs) such as vonoprazan are…
View details →DOI: 10.1007/s00535-026-02469-3 Negative / Null Result ReportMedicine
Wu, Liu, Wang et al. · 2026 · Scientific reports
Prolonged preoperative fasting is common in pediatric anesthesia, yet its effect on gastric residual volume (GRV) remains inadequately explored. We conducted a prospective cross-sectional study to examine the association between prolonged…
View details →DOI: 10.1038/s41598-026-57602-2 Negative / Null Result ReportMedicine
Costa de Oliveira, Caminha Souza, Cândido Alves et al. · 2026 · Clinical nutrition ESPEN
Breast cancer remains a critical global public health concern, with diet representing one of the primary modifiable lifestyle factors influencing both disease prevention and the risk of recurrence. This study aimed to evaluate the…
View details →DOI: 10.1016/j.clnesp.2026.103441 Negative / Null Result ReportMedicine
Pham, Vu, Le et al. · 2026 · PloS one
C5a and its receptor, C5aR, are involved in the degranulation of mast cells and basophils, leading to the release of proinflammatory cytokines. However, to date, their roles in the pathogenesis of chronic spontaneous urticaria (CSU) remain…
View details →DOI: 10.1371/journal.pone.0351329 