e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21720 results · page 384 of 724

Negative / Null Result ReportMedicine

Effect of Vitamin B12 Supplementation on Hematological and Athropometric Parameters in Children With Severe Acute Malnutrition, Aged 1 to 60 Months in Nutritional Rehabilitation Center (RCT).

Pathak BK, Maurya M, Mishra N et al. · 2026 · Clinical pediatrics

Microcytic hypochromic anemia is common in severe acute malnutrition (SAM) children, but macrocytic anemia (vitamin B12/folate deficiency) is not uncommon. Vitamin B12 deficiency leads to anemia and developmental slowing. We looked for the…

View details →DOI: 10.1177/00099228251415045
Negative / Null Result ReportMedicine

Short-Term Variability in Duplex-Derived Carotid Flow Parameters in Symptomatic Patients Awaiting Carotid Endarterectomy.

Bodegom ME, Hissink RJ, El Moumni M et al. · 2026 · Annals of vascular surgery

Background Carotid stenosis is traditionally considered a relatively stable condition between symptom onset and carotid endarterectomy. However, short-term changes in duplex-derived hemodynamic parameters may occur during the waiting…

View details →DOI: 10.1016/j.avsg.2026.03.002
Negative / Null Result ReportMedicine

Multi-perspective spatial memory representation in the presence of others.

Li J, Wang Q, Xie N et al. · 2026 · Cognitive processing

In order to better adapt to spatial environments, individuals often establish a spatial frame of reference system to represent objects and their positions within a scene. This study utilized a partial scene recognition paradigm across…

View details →DOI: 10.1007/s10339-025-01327-z
Negative / Null Result ReportMedicine

Exploring fMRI-neurofeedback to reduce craving-related brain activity in people with cannabis use disorder: A feasibility study.

Murphy E, Poudel G, Dakhili AH et al. · 2026 · Addictive behaviors

Introduction Cannabis Use Disorder (CUD) can come with intense cravings, which can trigger compulsive use/relapse, underscored by anterior cingulate cortex (ACC) hyperactivity during cannabis cue-reactivity functional neuroimaging (fMRI)…

View details →DOI: 10.1016/j.addbeh.2026.108741
Negative / Null Result ReportMedicine

Treatment in Public Centers for Adult Jewish Women Survivors of Childhood Sexual Abuse in Israel: Abuse Characteristics, Psychiatric Profiles, and One-Year Treatment Outcomes.

Lev-Ari L, Mintz Malchi K, Ludmir E et al. · 2026 · Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD)

Background Childhood sexual abuse (CSA) is associated with significant psychiatric morbidity and has been reported at notable rates among Jewish Israeli women. Yet data regarding abuse characteristics, psychiatric history and longitudinal…

View details →DOI: 10.1080/15299732.2026.2648314
Negative / Null Result ReportMedicine

Mavacamten Versus Alcohol Septal Ablation in Obstructive Hypertrophic Cardiomyopathy: An Echocardiography-Derived Pressure-Volume Analysis.

Reil JC, Sequeira V, Coppée C et al. · 2026 · Circulation. Heart failure

Background Obstructive hypertrophic cardiomyopathy (oHCM) is characterized by left ventricular (LV) outflow tract obstruction, which increases afterload and chronically activates the Anrep response, a compensatory (afterload-driven) state…

View details →DOI: 10.1161/circheartfailure.125.013392
Replication FailureOpen accessMedicine

The Effect of Hip Arthroplasty on Gait Function: Comparison of Ceramic-On-Ceramic Hip Resurfacing, Metal-On-Metal Hip Resurfacing, and Total Hip Arthroplasty.

Leon D, Maslivec A, Guest B et al. · 2026 · Journal of orthopaedic research : official publication of the Orthopaedic Research Society

Ceramic-on-ceramic hip resurfacing arthroplasty (CoC-HRA) has been developed to eliminate metal ion concerns which have been associated with metal-on-metal hip resurfacing arthroplasty (MoM-HRA) while maintaining similar functionality. The…

View details →DOI: 10.1002/jor.70112
Replication FailureMedicine

Acute overfeeding impairs meal-stimulated adipose tissue microvascular blood flow in healthy adults independent of changes in adiposity.

Brayner B, Mason S, Karimi E et al. · 2026 · American journal of physiology. Endocrinology and metabolism

Subcutaneous adipose tissue microvascular blood flow (MBF) increases in response to insulin or a meal, with gastric inhibitory polypeptide (GIP) being a proposed mechanism. This vascular response is blunted in people with insulin…

View details →DOI: 10.1152/ajpendo.00028.2026
Failed Experiment ReportMedicine

Randomized Controlled Trial of the Psychological and Clinical Outcomes of Reiki Plus Manual Therapy After Open Heart Surgery.

Zampino S, Hosler R, Brown K et al. · 2026 · The Journal of cardiovascular nursing

Background Reiki plus manual therapy are utilized to improve relaxation, sleep, emotional state, and pain. Evidence within hospital settings was limited, and previous studies had weak designs. Objective The purpose of this study was to…

View details →DOI: 10.1097/jcn.0000000000001334
Null DatasetOpen accessMedicine

Stabilization of Transport Properties in Thin Nonstoichiometric La<sub>1-x</sub>Sr<sub>x</sub>Mn<sub>y</sub>O<sub>3</sub> Films via Accelerated Aging for Magnetic Field Sensors.

Rudokas V, Koliada M, Stankevic V et al. · 2026 · Sensors (Basel, Switzerland)

Magnetic sensors based on the colossal magnetoresistance (CMR) effect in manganite thin films are promising for high-field measurements due to their wide operating range, low magnetoresistance anisotropy, and ability to function without…

View details →DOI: 10.3390/s26092711
Failed Experiment ReportMedicine

Post-orthotic brace upright radiographs in thoracolumbar compression fractures do not change initial management in the emergency department setting.

Randall MM, Uchimura RN, Steinmann JC et al. · 2026 · Injury

Introduction Vertebral compression fractures are common and incur significant healthcare costs. Orthotic bracing is a frequently used treatment; however, studies have shown uncertainty regarding its effectiveness. Upright radiographs after…

View details →DOI: 10.1016/j.injury.2026.113170
Abandoned HypothesisMedicine

We need to start thinking about thinking: The impact of rumination on OCD symptom improvement in exposure and response prevention.

McNamara ME, Becker MS, Nota JA et al. · 2026 · Journal of anxiety disorders

While rumination has been recognized in clinical settings as prevalent and problematic for individuals with obsessive compulsive disorder (OCD), its relationship to OCD symptom trajectories has been understudied. In a large sample of N =…

View details →DOI: 10.1016/j.janxdis.2026.103170
Negative / Null Result ReportOpen accessMedicine

Feasibility and Safety of a Computer-Controlled Device for Transradial Cerebral Angiography: A Prospective Pilot Study.

Tanaka S, Hirata K, Uramaru K et al. · 2026 · Journal of neuroendovascular therapy

Objective This study aimed to evaluate the feasibility and safety of a computer-controlled local anesthetic delivery device during transradial cerebral angiography and to descriptively assess procedural pain and hemodynamic changes in an…

View details →DOI: 10.5797/jnet.oa.2026-0040
Negative / Null Result ReportMedicine

Peripheral endothelial and coronary microvascular responses to lipophilic versus hydrophilic ACE inhibitors in newly diagnosed hypertension.

Yilmaz Y, Celik FB, Atici A et al. · 2026 · Journal of hypertension

Background The clinical relevance of tissue-selectivity among angiotensin-converting enzyme (ACE) inhibitors is debated. This study aimed to compare the effects of a lipophilic (quinapril) and a hydrophilic (lisinopril) ACE inhibitor on…

View details →DOI: 10.1097/hjh.0000000000004357
Negative / Null Result ReportOpen accessMedicine

Discordant Perioperative Prophylaxis and Major Morbidity After Pancreatoduodenectomy in Patients Undergoing PTBD: A Culture-Based Analysis.

Korkmaz YY, Gungor F, Kudas I et al. · 2026 · Journal of clinical medicine

Background : Patients undergoing pancreatoduodenectomy (PD) after preoperative percutaneous transhepatic biliary drainage (PTBD) frequently develop bacterobilia. While bile culture positivity has been variably linked to postoperative…

View details →DOI: 10.3390/jcm15062280
Negative / Null Result ReportOpen accessMedicine

Physical activity levels, sleep quality and perceived stress in Chilean students: a cross-sectional study.

Aguilera-Eguía R, Fuentes-Barría H, Avilés-Santos Y et al. · 2026 · Frontiers in sports and active living

Objective To describe sleep quality, perceived stress, and physical activity levels, as well as to identify the associations between these variables in fourth-year Kinesiology students at the Catholic University of the Most Holy Conception…

View details →DOI: 10.3389/fspor.2026.1789806
Negative / Null Result ReportOpen accessMedicine

Perioperative Anesthetic Factors and Flap Outcome in Pediatric Head and Neck Free Flap Reconstruction: A Retrospective Study.

Lech D, Maksymowicz R, Matysek J et al. · 2026 · Journal of clinical medicine

Background: Microvascular free flap reconstruction is an established method for the management of complex head and neck defects in pediatric patients. However, the influence of perioperative anesthetic management on flap outcome in this…

View details →DOI: 10.3390/jcm15114321
Negative / Null Result ReportMedicine

Lanthanum carbonate lowers serum phosphorus without altering body phosphorus burden in maintenance peritoneal dialysis patients: a randomized crossover trial.

Kopple JD, Bross R, Ekramzadeh M et al. · 2025 · The American journal of clinical nutrition

Background Many studies show that intestinal phosphate binders reduce serum phosphorus concentrations in hyperphosphatemic patients with chronic kidney failure. To our knowledge, there are virtually no studies of the effect of these…

View details →DOI: 10.1016/j.ajcnut.2025.08.015
Negative / Null Result ReportMedicine

Prospective Monitoring of Serum Values of CBC, Total IgE, Thyroid Findings, D-Dimer, Vitamin D, and Inflammatory Molecules CRP, ESR, and IL-6 and Clinical Features of Chronic Spontaneous Urticaria Patients During Antihistamine Treatment.

Kuna M, Štefanović M, Barac E et al. · 2026 · International journal of molecular sciences

Having appropriate and meaningful diagnostic procedures is crucial in the approach to patients with chronic spontaneous urticaria (CSU), so we wanted to investigate relationships between CSU patients' common serum factors and clinical CSU…

View details →DOI: 10.3390/ijms27052503
Negative / Null Result ReportOpen accessMedicine

Analysis of PR-1, PR-2, PR-10, chitinases and chitinase-like proteins genes expression in pea roots under the action of salicylic acid and methyl jasmonate.

Egorova AM · 2026 · Vavilovskii zhurnal genetiki i selektsii

Stress phytohormones - salicylic and jasmonic acids - participate in the plant defense response. The increase in the content of these compounds during plant infection by pathogens leads to the activation of signaling pathways, ultimately…

View details →DOI: 10.18699/vjgb-26-24
Negative / Null Result ReportMedicine

Advances in Marfan Syndrome Care: The Limits of Type B Dissection.

Tchitchinadze M, Milleron O, Eliahou L et al. · 2026 · The Annals of thoracic surgery

Background To evaluate the progress of care for patients with Marfan syndrome with FBN1 pathogenic variant carriers over the past 30 years. Methods Patients who visited the center were entered into a prospective registry. Aortic events…

View details →DOI: 10.1016/j.athoracsur.2026.01.045
Negative / Null Result ReportMedicine

Return to Driving After Anterior Total Hip Arthroplasty.

Masturov YA, Hogan WB, Regal S et al. · 2026 · Orthopedics

Background Traditional guidance after posterior-approach total hip arthroplasty (THA) recommends return to driving at 6-8 weeks. Muscle-sparing direct anterior THA (A-THA) may enable earlier recovery. Our objective was to assess brake…

View details →DOI: 10.3928/01477447-20260113-01
Negative / Null Result ReportMedicine

Structure of sulfur chains encapsulated in single-walled carbon nanotubes.

Saiful Islam M, Fujimori T, Miyanaga T et al. · 2025 · Journal of physics. Condensed matter : an Institute of Physics journal

The encapsulation of sulfur (S) within single-walled carbon nanotubes (S@SWCNTs) provides a unique opportunity to stabilize and study the structure and bonding of one-dimensional sulfur chains, which do not exist in a free state. In this…

View details →DOI: 10.1088/1361-648x/ae2f88