Negative / Null Result ReportMedicine
Kharazmi K, Saroughi M, Khoshniat MT et al. · 2026 · Naunyn-Schmiedeberg's archives of pharmacology
Lead exposure is linked to various adverse effects on human health, including toxicity to multiple organs such as the kidneys, liver, and reproductive system. Lead induces its toxic effects through complex pathways, including mitochondrial…
View details →DOI: 10.1007/s00210-026-05422-6 Negative / Null Result ReportMedicine
Carboni F, Bechi N, Proietti D et al. · 2026 · Carbohydrate polymers
Glycoconjugate vaccines are effective against bacterial infections. Key characteristics for optimal immunogenicity are the carbohydrate-to-protein ratio and consequent glycosylation density. Directing the conjugation to specific sites is…
View details →DOI: 10.1016/j.carbpol.2026.125250 Negative / Null Result ReportMedicine
Toomey D, Lewis G, Rashid U et al. · 2026 · Neuromodulation : journal of the International Neuromodulation Society
Background Exercise induces short-term pain relief (exercise-induced hypoalgesia, EIH), but this response is often blunted in people with knee osteoarthritis (OA). Transcranial direct current stimulation (tDCS) has been proposed as a…
View details →DOI: 10.1016/j.neurom.2026.01.011 Negative / Null Result Report
Beffara B, Hadj-Bouziane F, Ben Hamed S et al. · 2026 · Preprint
The control of selective visuo-spatial attention is known to rely on multiple signals, including reward. While most attention control signals are well acknowledged to interact with each other, the case of reward has led to mixed findings…
View details →DOI: 10.31234/osf.io/zgkj8_v1 Negative / Null Result Report
Banerjee S, Chopra E, Smith IM et al. · 2026 · Preprint
ABSTRACT Estradiol (E2) is a potent estrogen molecule that plays a crucial role in regulating numerous healthy and pathophysiological processes. To model estrogen-dependent cellular activities in vitro in a physiologically meaningful way,…
View details →DOI: 10.64898/2025.12.31.697205 Negative / Null Result ReportMedicine
El-Karim RMG, Ali REM, Habib MR et al. · 2026 · Acta parasitologica
Bachground Schistosomiasis remains difficult to control due to persistent transmission via freshwater snails and reliance on praziquantel (PZQ) as the primary treatment. Novel adjunctive strategies targeting multiple stages of the parasite…
View details →DOI: 10.1007/s11686-026-01274-5 Negative / Null Result Report
Gupta BK, Pandey R, Thapa N et al. · 2026 · Preprint
Abstract Background Myocardial infarction (MI) remains a leading cause of morbidity and mortality worldwide, with South Asian populations facing a disproportionately high burden. In Nepal, the incidence of MI has been rising, and recent…
View details →DOI: 10.21203/rs.3.rs-9141505/v1 Negative / Null Result ReportMedicine
Madrid J, Batzianouli E, Rutz D et al. · 2026 · Journal of Parkinson's disease
BackgroundFreezing of gait (FOG) in Parkinson's disease (PD) is a major cause of disability and falls and often responds incompletely to conventional therapy. Rehabilitative interventions including cognitive strategies and sensory cueing…
View details →DOI: 10.1177/1877718x261416181 Negative / Null Result ReportMedicine
Fellin CR, Steiner RC, Buchen JT et al. · 2026 · Photobiomodulation, photomedicine, and laser surgery
Background Nerve guidance conduits (NGCs) are a clinically approved option for peripheral nerve repair but remain ineffective compared with autograft "gold standard" treatment options. A combinatorial approach to conduit-based peripheral…
View details →DOI: 10.1177/25785478251414510 Negative / Null Result ReportMedicine
Oncul S, Lee H, Singh S et al. · 2026 · Journal of immunology (Baltimore, Md. : 1950)
B cells constitute ∼15% to 20% of tumor-infiltrating lymphocytes in melanoma. Their presence in the tumor microenvironment correlates with improved survival and enhanced response to immune checkpoint blockade therapy. Yet, the functional…
View details →DOI: 10.1093/jimmun/vkag004 Negative / Null Result ReportMedicine
Bergen MA, Kim J, Piana LE et al. · 2026 · The Journal of hand surgery
Purpose To evaluate the biomechanical performance of the modified Brunelli scapholunate interosseous ligament (SLIL) reconstruction with and without suture augmentation, using a cadaveric model under cyclic loading conditions. Methods…
View details →DOI: 10.1016/j.jhsa.2025.12.024 Negative / Null Result ReportMedicine
Riesenbach IC, Tsomik G, Chiasson M et al. · 2026 · Aquaculture.
Insects, such as black soldier flies (BSF), have garnered attention in the aquaculture industry as a sustainable protein and lipid alternative to fishmeal and fish oil. However, research is lacking on which components of BSF improve fish…
Negative / Null Result Report
Salinas-Marcos J, Cruz-Luis J, Aguirre L · 2025 · Preprint
The “algarrobo”, Neltuma pallida is a key tree species in the seasonally dry tropical forests in Equatorial Pacific South America, currently at risk. Its regeneration depends on endozoochorous seed dispersal, in which seeds are ingested…
View details →DOI: 10.20944/preprints202511.1812.v1 Negative / Null Result ReportMedicine
Nakajima K, Ishida Y, Miura D et al. · 2026 · Odontology
This study investigated the effects of air abrasion with different abrasive particles on the surface roughness and bond strength of resin-based luting agents to enamel and dentin, including dentin surfaces treated with immediate dentin…
View details →DOI: 10.1007/s10266-025-01293-0 Negative / Null Result Report
Fleming HA, Whines A, Whelehan P et al. · 2025 · Preprint
Central to survival is our ability to learn that the sensory properties of food are associated with metabolic interoceptive signals (e.g., changing blood glucose). These signals influence cognition and brain activity, shaping the hedonic…
View details →DOI: 10.31234/osf.io/px3ub_v2 Negative / Null Result ReportMedicine
Lagravinese G, Castellana G, Genco M et al. · 2026 · Applied psychophysiology and biofeedback
Chronic obstructive pulmonary disease (COPD) is associated with persistent dyspnea, reduced functional capacity, and significant cognitive and affective impairments. Pulmonary rehabilitation improves the physical and psychological…
View details →DOI: 10.1007/s10484-025-09763-5 Negative / Null Result Report
Nilsson M, Berrebi J, Nikkhou-Aski S et al. · 2025 · Preprint
BackgroundThe hippocampus is crucial for learning, memory, and stress regulation but is vulnerable to biological and environmental influences that compromise its structural and metabolic integrity. Proton magnetic resonance spectroscopy…
View details →DOI: 10.31234/osf.io/gcmsq_v1 Negative / Null Result ReportMedicine
Oboite FO, Spencer S · 2025 · Forest Ecology and Management.
Salvage logging is widely used after wildfires to recover economic value and facilitate regeneration, yet its effects on post-fire recovery remain uncertain. The 2003 McLure fire in southern interior British Columbia burned a landscape…
Negative / Null Result Report
Meier M, Merz CJ, Rüttgens T et al. · 2025 · Preprint
Stress and the associated cortisol release have profound effects on long-term memory (LTM). While glucose can increase the cortisol stress response and exhibits memory enhancing effects in non-stressful situations, the interaction of…
View details →DOI: 10.31234/osf.io/vjmk2_v2 Negative / Null Result ReportMedicine
Dalmeijer SWR, Zweedijk BE, Boldewijn DF et al. · 2026 · Surgical oncology
Purpose Accurate intraoperative localization of small intestinal neuroendocrine tumors (SI-NETs) remains a surgical challenge, with standard staging protocols frequently missing small primary or metastatic lesions. ICG has shown utility in…
View details →DOI: 10.1016/j.suronc.2026.102443 Negative / Null Result ReportMedicine
Broadley D, Le Riche A, Yu Y et al. · 2026 · International journal of molecular sciences
Androgen receptor (AR) signaling plays a key role in male pattern baldness. We investigated whether targeting Dickkopf 1 ( DKK1 ) and Secreted frizzled-related protein 1 ( SFRP1 ), two AR-regulated genes, offers a novel therapeutic…
View details →DOI: 10.3390/ijms27041815 Negative / Null Result Report
Chamily FA, Vanderklok BR, Buzinski OD et al. · 2025 · Preprint
Environmental enrichment can have complex, contradictory effects on aggression and animal welfare. Although increasing enrichment may reduce aggression by limiting the visibility of competitors, it may also intensify territorial defense…
View details →DOI: 10.64898/2025.12.11.693693 Negative / Null Result ReportMedicine
Essang S, Iyer A, Durantini AM et al. · 2026 · Photochemistry and photobiology
Singlet oxygen ( 1 O 2 ) is a reactive species that plays a role in environmental and biological surface chemistry; however, the mechanisms of the association of airborne 1 O 2 at the air/surface interface are poorly known. Here, we help…
View details →DOI: 10.1111/php.14125 Negative / Null Result ReportMedicine
Pister ML, Brost KN, Campbell JM et al. · 2025 · Journal of dairy science
Feeding plasma protein has been shown to have health benefits and help ameliorate stress in preweaning calves, aiding their ability to handle the challenges of weaning and initial social interactions. We hypothesized that feeding plasma…
View details →DOI: 10.3168/jds.2025-26693 Negative / Null Result Report
Freislederer F, Dimitriu M, Audigé L et al. · 2025 · Preprint
Abstract Background The subacromial bursa is a key source of mesenchymal stem cells that may support rotator cuff tendon healing. Since microvascularization contributes to tendon repair, we aimed to examine postoperative…
View details →DOI: 10.21203/rs.3.rs-6545398/v1 Negative / Null Result Report
Prado E, Argioli AS, Funichello M et al. · 2025 · Preprint
Abstract Agricultural adjuvants are among the most critical factors influencing spray deposition and herbicide efficacy against weeds. This study evaluated spray deposition parameters by spraying different non-ionic adjuvants on Euphorbia…
View details →DOI: 10.21203/rs.3.rs-6474409/v1 Negative / Null Result ReportMedicine
Bertret V, Latimier RLG, Monbet V · 2025 · Water research
This study compares various modeling approaches to predict ammonium concentration in wastewater treatment plants (WWTPs), with a focus on integrating data assimilation techniques. It explores white-box, grey-box, and black-box models,…
View details →DOI: 10.1016/j.watres.2025.123673 Negative / Null Result ReportMedicine
Harlev C, Bue M, Petersen EK et al. · 2025 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Background Epithelial ovarian cancer remains a leading cause of mortality among gynecological malignancies, with a high incidence of peritoneal carcinomatosis at diagnosis. Hyperthermic intraperitoneal chemotherapy (HIPEC) has emerged as a…
View details →DOI: 10.1016/j.ejso.2025.110378 Negative / Null Result Report
Sato H, Sumida A · 2025 · Preprint
Conifers generally exhibit narrow, deep crowns, whereas broadleaf trees typically form spherical crowns. A widely accepted hypothesis attributes this difference to variation in solar angles: conifers, which prevail in high-latitude regions…
View details →DOI: 10.22541/au.174192316.68245617/v1 Negative / Null Result ReportOpen accessMedicine
Pihlaja S, Lipsanen J, Ritola V et al. · 2026 · Frontiers in psychology
Among patients receiving internet-delivered cognitive behavioral therapy (iCBT) for depression in routine clinical practice, 101 patients were randomized to either iCBT as usual or to iCBT with add-on scheduled telephone support (STS).…
View details →DOI: 10.3389/fpsyg.2026.1704049 