B cell depletion promotes melanoma tumor growth in a CD4+ T cell-dependent manner.
Oncul S; Lee H; Singh S; Yee C; Afshar-Kharghan V · 2026 · Journal of immunology (Baltimore, Md. : 1950)
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
B cells constitute ∼15% to 20% of tumor-infiltrating lymphocytes in melanoma. Their presence in the tumor microenvironment correlates with improved survival and enhanced response to immune checkpoint blockade therapy. Yet, the functional…
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Metadata source: Europe PMC · DOI 10.1093/jimmun/vkag004