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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

19859 results in Negative / Null Result Report · page 378 of 662

Negative / Null Result ReportMedicine

Pre-processing and thermal treatment modulate structure, solubility and digestibility of faba bean protein isolates: A structure–function perspective

Sharma N, Gwala S, Owens RA et al. · 2026 · Food Hydrocolloids.

Despite growing interest in faba bean (Vicia faba L.) as a sustainable plant protein source, limited studies address process-induced structural mechanisms linking functionality with gastro-intestinal (GI) digestion. This study elucidates…

Negative / Null Result ReportMedicine

Do steroids improve outcomes of idiopathic sixth nerve palsy in children?

Sternfeld A, Goren L, Ehrenberg M et al. · 2026 · Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Purpose To analyze the effect of systemic steroid treatment in children with benign acquired isolated sixth nerve palsy (BAISNP) regarding healing, recurrence risk and late sequelae. Methods A retrospective cohort design was used. The…

View details →DOI: 10.1007/s00417-026-07286-1
Negative / Null Result ReportMedicine

Haemodynamic effects of low versus high dialysate temperature in haemodialysis patients: a single-blinded, randomised, cross-over study.

Jørgensen IEH, Jensen JSK, Buus NH et al. · 2026 · BMC nephrology

Background Cooling of the dialysate may improve intradialytic haemodynamics. This study compared low dialysate temperature (LDT) of 35 °C with high dialysate temperature (HDT) of 37 °C (standard) in terms of blood pressure (BP),…

View details →DOI: 10.1186/s12882-026-04990-2
Negative / Null Result Report

Fiscal Rule Stretching in the European Union: The Impact of Elections, Financial Stress, and Excessive Deficit Procedures on Government Debt Revisions

Bhuekar A · 2026 · Preprint

This paper examines the strategic manipulationof government debt data—referred to as ”fiscal rule stretch-ing”—among European Union member states, particularly inresponse to electoral incentives, financial market stress, and theconstraints…

View details →DOI: 10.20944/preprints202603.0301.v1
Negative / Null Result ReportMedicine

Data accuracy of prescriptions reported to the Arkansas prescription drug monitoring program.

Embry K, Cima L, Turpin J et al. · 2026 · Journal of the American Pharmacists Association : JAPhA

Background Prescription Drug Monitoring Programs (PDMPs) are databases for controlled substances dispensed from retail pharmacies. Although all 50 states operate their own PDMP, only a few have assessed the accuracy of the data being…

View details →DOI: 10.1016/j.japh.2026.103138
Negative / Null Result ReportMedicine

Climatic impact on ram lamb reproductive development: the effect of solar radiation.

Gómez-Vargas JC, Parra-Bracamonte GM, Muñoz-García C et al. · 2026 · Animal : an international journal of animal bioscience

Climate change has a significant impact on global animal production. The objective was to evaluate the long-term effects of direct solar radiation on reproductive development in Pelibuey ram lambs under heat stress. Eighteen ram lambs (6.9…

View details →DOI: 10.1016/j.animal.2026.101868
Negative / Null Result ReportMedicine

Interhospital transfer dynamics in foreign body aspiration: Age-stratified nationwide retrospective cohort study.

Deniz MS, Çiflik KB, Özdemir Çiflik B et al. · 2026 · Turk gogus kalp damar cerrahisi dergisi

Background Foreign body aspiration (FBA) is an acute clinical emergency that is particularly common in the pediatric population and, if not managed promptly, can lead to serious morbidity and mortality across all age groups. The need for…

View details →DOI: 10.4274/tjtcs.2026.2026-4-11
Negative / Null Result ReportMedicine

Evaluating the predictive utility of European-based and transethnic polygenic risk scores for kidney function in older Black adults: insights from the Health and Retirement Study.

Cobb RJ, Thorpe RJ Jr, Norris KC · 2026 · The journals of gerontology. Series A, Biological sciences and medical sciences

Background Black populations in the U.S. experience a disproportionately faster progression of chronic kidney disease than the general population. Polygenic risk scores (PRS) are a promising tool for risk stratification, yet their utility…

View details →DOI: 10.1093/gerona/glag122
Negative / Null Result ReportMedicine

[Exploration of the value of VAS score in the diagnosis and treatment of patients with vestibular diseases during caloric test].

Tian L, Liu X, Yu J et al. · 2026 · Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery

Objective: To identify the factors influencing the visual analogue scale(VAS) scores for distress experienced by patients with vestibular diseases during caloric tests, and to explore the value of VAS scores in disease diagnosis and…

View details →DOI: 10.13201/j.issn.2096-7993.2026.06.002
Negative / Null Result ReportMedicine

Echolocating free-tailed bats use vision and hearing but not magnetoreception when navigating a maze.

Lemus K, Meyers R, Ellis S et al. · 2026 · Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology

Insectivorous bats navigate mainly by echolocation, but may also use visual, olfactory, and magnetic cues when travelling long distances. Parsing the relative contributions of different senses for navigation is difficult in wild bats. In…

View details →DOI: 10.1007/s00359-026-01813-5
Negative / Null Result ReportMedicine

Effects of Psychosocial Interventions on Measures of Stress Among Breast Cancer Survivors: A Scoping Review.

Cousin L, Guillen S, Behar-Horenstein LS et al. · 2026 · Cancer nursing

Background With 4 million breast cancer survivors (BCSs) in the United States, researchers are interested in mitigating the effects of stress after cancer diagnosis. This stress can affect immune and endocrine systems, elevating cancer…

View details →DOI: 10.1097/ncc.0000000000001550
Negative / Null Result ReportMedicine

Health behaviors of young adults in the context of preventing cardiovascular diseases caused by atherosclerosis.

Kawalec-Kajstura E, Kopeć M, Sułkowska J et al. · 2025 · Folia medica Cracoviensia

Introduction Cardiovascular diseases caused by atherosclerosis are one of the leading causes of death in Poland and worldwide. Atherosclerosis develops from the earliest years of life and is influenced by modifiable risk factors resulting…

View details →DOI: 10.24425/fmc.2025.156703
Negative / Null Result ReportMedicine

Ultrasonographic optic nerve sheath diameter for predicting elevated intracranial pressure and clinical severity in children: a prospective observational study.

Naseem M, Anand V, Das R et al. · 2026 · European journal of pediatrics

Elevated intracranial pressure (ICP) can complicate various neurological conditions in children and may result in fatal brainstem herniation. Early detection and management can prevent this fatal complication. This prospective…

View details →DOI: 10.1007/s00431-026-07053-8
Negative / Null Result ReportMedicine

The Impact of the Number of Implantation-Window uNK Cells on Pregnancy Outcomes and Decidualization.

Huang B, Ma Y, Rao F et al. · 2026 · Reproductive sciences (Thousand Oaks, Calif.)

This study aims to further clarify the correlation between the quantity of natural killer (NK) cells in the endometrium and the successful implantation of embryos during the specific implantation window. Patients were stratified into four…

View details →DOI: 10.1007/s43032-026-02125-4
Negative / Null Result ReportMedicine

Comparative Analysis of Proton and Carbon-Ion Therapy for Head and Neck Cancer: LET-Dependent α/β Ratios in EQD2 and NTCP.

Wakisaka Y, Miyasaka Y, Tominaga Y et al. · 2026 · Radiation research

Proton therapy (PT) and carbon-ion therapy (CIT) differ not only in their physical dose characteristics but also in their biological effects, attributable to variations in fractionation protocols and linear energy transfer (LET). These…

View details →DOI: 10.1667/rade-25-00183.1
Negative / Null Result ReportMedicine

Threat or opportunity? Challenge vs hindrance appraisals of generative AI and self-regulated teaching among pre-service EFL teachers: A COR perspective.

Liu F, Wu H · 2026 · Acta psychologica

This study investigates how Chinese pre-service teachers of English as a foreign language (EFL) develop self-regulated teaching competencies in the face of disruptions posed by generative artificial intelligence (GenAI) and structural…

View details →DOI: 10.1016/j.actpsy.2026.106747
Negative / Null Result ReportMedicine

Structural reconfiguration of gluten-starch matrices driven by yeast fermentation and its effects on quality of fermented dried noodles.

Zhang G, Zhao P, Zhu L et al. · 2026 · Food chemistry

This study aimed to systemically investigate the effects of yeast fermentation (0-2% yeast, flour basis; 0.5-2 h) on gluten and starch structures, and cooking and textural properties of fermented dried noodles (FDN). Yeast fermentation…

View details →DOI: 10.1016/j.foodchem.2026.149417
Negative / Null Result ReportMedicine

Dysregulation of HIF-1α-regulated and thromboinflammatory genes may contribute to thrombotic risk in patients with BCR::ABL1-negative myeloproliferative neoplasms.

Morath O, Wolfrum T, Crodel C et al. · 2026 · Journal of thrombosis and haemostasis : JTH

Background Hypoxia-inducible factor-1α (HIF-1α) regulates multiple pathways involved in metabolism, inflammation, and coagulation and may contribute to thrombotic complications in patients with BCR::ABL1-negative myeloproliferative…

View details →DOI: 10.1016/j.jtha.2026.04.013
Negative / Null Result ReportMedicine

Persistent Chemotherapy-Induced Alopecia: Updates in Diagnosis and Treatment Persistent Chemotherapy Induced Alopecia: An Updated Approach.

Garza-Rodríguez V, Imbernon-Moya A, Hermosa-Gelbard A et al. · 2026 · Actas dermo-sifiliograficas

Chemotherapy-induced alopecia (CIA) is characterized by absent or incomplete hair regrowth after completion of chemotherapy. Alopecia that persists beyond 6 months after completing chemotherapy is defined as persistent chemotherapy-induced…

View details →DOI: 10.1016/j.ad.2026.104660
Negative / Null Result ReportMedicine

Autopolyploidy exacerbates dominance masking under negative frequency-dependent selection: evidence from sporophytic self-incompatibility in Arabidopsis arenosa and Arabidopsis lyrata.

Vekemans X, Kolesnikova U, Vlček J et al. · 2026 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences

Polyploidy is widespread within flowering plants, with 35% of extant species being recent polyploids. Whether and how polyploidy modulates the action of natural selection remains debated, and the particular case of balancing selection has…

View details →DOI: 10.1098/rstb.2025.0182
Negative / Null Result ReportMedicine

Asthma in Active Military Aircrew: Long-term Health and Flight Performance.

Angel O, Rittblat M, Freund O et al. · 2026 · The Israel Medical Association journal : IMAJ

Background Asthma poses unique challenges in aviation medicine. While strict criteria typically dictate waiver approvals in military aviators with asthma, the Israeli Air Force (IAF) applies a more individualized approach. Still, evidence…

Negative / Null Result ReportMedicine

Combined Hormonal Contraception with Low-Dose Ethinylestradiol is Associated with Modest Reduction of Breast Milk Volume when Administered Vaginally, but Not Orally.

Segev L, Weitzman G, Hijazi B et al. · 2026 · Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine

Background Combined hormonal contraception (CHC) is habitually not prescribed to breastfeeding women due to concerns of decreased milk production. This habit is based on inconclusive studies that examined lactation suppression of CHC with…

View details →DOI: 10.1177/15568253261450161