Negative / Null Result Report
Sobhi A, Hegazy RM, Zolfakar DS et al. · 2026 · Preprint
Abstract Purpose Ovarian lesions are common diseases nowadays that should be diagnosed accurately. The Ovarian-Adnexal Reporting and Data System (O-RADS) classification helps to a great extent in categorizing the type of ovarian lesions,…
View details →DOI: 10.21203/rs.3.rs-8573044/v1 Negative / Null Result Report
Mayorga AP, Peña CO, Muñoz DB et al. · 2026 · Preprint
Abstract Background The rapid urease test (RUT) is widely used for Helicobacter pylori (H. pylori) diagnosis, but its diagnostic performance in advanced gastric atrophy remains poorly characterized. Aims To evaluate RUT accuracy against…
View details →DOI: 10.21203/rs.3.rs-9490483/v1 Negative / Null Result ReportMedicine
Abi Kheir DJ, Moriles K, Carr AL et al. · 2026 · The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians
Background: The (1,3)-β-D-glucan (BDG) test can be used as a stewardship approach to decrease antifungal overutilization, development of resistance, and excess costs. Objective: This study assessed the impact that a BDG algorithm has on…
View details →DOI: 10.1177/87551225261446911 Negative / Null Result ReportMedicine
Auer A, Settypalli TBK, Rozstalnyy A et al. · 2026 · BMC veterinary research
Background Rapid diagnosis is critical for the early detection and control of transboundary animal diseases such as African Swine Fever (ASF) and Avian Influenza (AI), particularly because it enables timely containment measures at the farm…
View details →DOI: 10.1186/s12917-026-05606-5 Negative / Null Result Report
Zougmore WAMJ, Kaboré NF, Bado P et al. · 2026 · Preprint
Abstract Background : Human Papillomavirus (HPV) testing is recommended as a high-performance screening method within the World Health Organization (WHO) global strategy for cervical cancer elimination. However, the programmatic…
View details →DOI: 10.21203/rs.3.rs-9484224/v1 Negative / Null Result ReportOpen accessMedicine
Saliba M, Haddad E · 2026 · International journal of surgery case reports
Introduction The most common type of vulvar cancer is squamous cell carcinoma. The management of early-stage vulvar squamous cell carcinoma includes radical local excision of the primary tumor. Evaluation of sentinel nodes for metastases…
View details →DOI: 10.1097/rc9.0000000000000450 Negative / Null Result ReportOpen accessMedicine
Lindsley IC, Juman MM, Seifert SN et al. · 2026 · PLoS neglected tropical diseases
Large host-virus association databases are increasingly used to explore broad questions in disease ecology, particularly around host range, pathogen diversity, and the potential for spillover. While these databases have been instrumental…
View details →DOI: 10.1371/journal.pntd.0013343 Negative / Null Result Report
Wright L, Hamze J, Nagrani TR et al. · 2026 · Preprint
Abstract Background Coronary artery disease (CAD) places a disproportionate burden on rural Appalachian communities. Scioto County, Ohio has among the highest rates of CAD-related hospitalizations in the state, approaching double the…
View details →DOI: 10.21203/rs.3.rs-9246863/v1 Negative / Null Result ReportMedicine
Ibrahim M, Mostafa D, Manie EA et al. · 2026 · British poultry science
1. This study used unvaccinated sentinels plus Avian Influenza Virus (AIV) specific ELISA for differentiating infected from vaccinated animals (DIVA). Birds assessed were from 10 broiler flocks (F1-F10), three layer (F11-F13) and two…
View details →DOI: 10.1080/00071668.2026.2645007 Negative / Null Result ReportOpen accessMedicine
Tavoly M, Jørgensen CT, Sandblad KG et al. · 2026 · Research and practice in thrombosis and haemostasis
Background It has been suggested that D-dimer testing should be avoided in patients with prolonged symptoms, as results may yield false negatives. However, the evidence supporting this recommendation is limited. Objectives This study…
View details →DOI: 10.1016/j.rpth.2026.103457 Failed Experiment ReportMedicine
Loeb SA, Tharp DL, Zawieja SD et al. · 2026 · Journal of cardiovascular pharmacology
Over 30 million individuals globally are afflicted with heart failure with preserved ejection fraction (HFpEF). Despite this substantial figure, treatment options for HFpEF remain limited. This is largely attributed to the variability in…
View details →DOI: 10.1097/fjc.0000000000001844 Negative / Null Result ReportOpen accessMedicine
Otwell T, Knight B, Coryell M et al. · 2025 · Frontiers in cellular and infection microbiology
Molecular diagnostic assays are critical tools to test, diagnose and treat infectious and other diseases. For example, PCR test results have been extremely valuable during the COVID-19 pandemic, not only to provide appropriate health care…
View details →DOI: 10.3389/fcimb.2025.1524025 Negative / Null Result ReportMedicine
Gudmundsdottir H, Hernandez-Delima FJ, McDowell BC et al. · 2026 · Surgery
Background Regional lymph node involvement impacts prognosis for patients with pancreatic neuroendocrine tumors and may influence management decisions for small tumors. Conventional cross-sectional imaging modalities have low sensitivity…
View details →DOI: 10.1016/j.surg.2026.110136 Negative / Null Result ReportOpen accessMedicine
Khoshakhlagh M, Dehghani T, Alizadeh A et al. · 2026 · Iranian journal of pathology
Background & objective Real-time PCR is widely used to detect SARS-CoV-2, the virus responsible for COVID-19, but false-negative results can occur even with internal controls. This study aimed to investigate the impact of using alternative…
View details →DOI: 10.30699/ijp.2025.2053609.3417 Negative / Null Result ReportOpen accessMedicine
Cañete FT, Williams L, Parry R et al. · 2026 · Forensic science international. Synergy
The Phadebas® Forensic Press Test (PFPT) is widely employed in forensic laboratories for presumptive saliva screening by observation of α-amylase activity. This enzyme hydrolyses starch embedded in the test paper, resulting in a blue…
View details →DOI: 10.1016/j.fsisyn.2026.100691 Negative / Null Result Report
Lesmanawati DAS, Widiasta A, Ghrahani R et al. · 2026 · Preprint
Abstract Background Patients with systemic lupus erythematosus (SLE) are at increased risk of tuberculosis (TB) because of disease-related immune dysregulation and prolonged immunosuppressive therapy. Screening for latent TB infection…
View details →DOI: 10.21203/rs.3.rs-9728431/v1 Negative / Null Result ReportMedicine
Liu M, Kong L, Sun W et al. · 2026 · Journal of immunotherapy (Hagerstown, Md. : 1997)
To investigate the clinical profile of nivolumab-induced autoimmune hemolytic anemia (AIHA) and to reveal the diagnostic and therapeutic patterns of this disease. Articles on nivolumab-induced AIHA published before October 31, 2025 were…
View details →DOI: 10.1097/cji.0000000000000612 Negative / Null Result ReportMedicine
Costa M, Rodrigues P, Araújo B et al. · 2026 · Diagnostic microbiology and infectious disease
Cryptococcal meningitis is a life-threatening opportunistic infection in advanced HIV disease. Cryptococcal antigen (CrAg) detection by lateral flow assay (LFA) is the diagnostic cornerstone, offering high sensitivity and specificity.…
View details →DOI: 10.1016/j.diagmicrobio.2026.117512 Negative / Null Result ReportMedicine
Li QX, Luo LZ · 2026 · BMC infectious diseases
Background Cutaneous infections caused by non-tuberculous mycobacteria (NTM) are rare. Atypical clinical manifestations and the need for precise microbiological identification often result in misdiagnosis and underdiagnosis. Case…
View details →DOI: 10.1186/s12879-026-13549-3 Negative / Null Result ReportOpen accessMedicine
Gambuś K, Moszczyński K, Popovchenko S et al. · 2026 · Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery
Introduction Accurate assessment of mediastinal lymph node involvement is crucial for treatment planning in lung cancer. Combined endobronchial and endoscopic ultrasound (CUS) offers high sensitivity and negative predictive value (NPV),…
View details →DOI: 10.5114/kitp.2026.160677 Negative / Null Result Report
Alger JR, Gupta I, Farkouh L et al. · 2026 · Preprint
Background Prior neuroimaging suggests brain differences between children with attention deficit hyperactivity disorder due to prenatal alcohol exposure (ADHD+PAE) and non-exposed children with ADHD due to other, e.g., familial, causes…
View details →DOI: 10.64898/2026.05.25.26354065 Negative / Null Result ReportMedicine
Dellbrügge F, Schaumann N, Kruppa M et al. · 2026 · Pneumologie (Stuttgart, Germany)
Abstract We present the case of a 39-year-old Indian female patient diagnosed with tuberculous mastitis and lymph node tuberculosis. The patient had a history of tuberculosis infection treatment as a newborn. She initially presented with…
View details →DOI: 10.1055/a-2845-3440 Negative / Null Result ReportMedicine
Li X, Huang Y, Hao J et al. · 2026 · Current HIV research
Background Married Men who have Sex with Men (MSM) constitute a bridge population for HIV diffusion into low-risk groups, with spousal non-disclosure rates exceeding 60% in China. It will increase the risk of secondary transmission within…
View details →DOI: 10.2174/011570162x444930260409114355 Negative / Null Result ReportMedicine
Tsang SM, Merino Gutierrez V, Yu J et al. · 2026 · Veterinary sciences
Canine babesiosis caused by Babesia gibsoni is prevalent in Hong Kong. While molecular diagnosis via PCR is highly sensitive, it typically requires reference laboratory access, delaying clinical decisions. This study evaluated the…
View details →DOI: 10.3390/vetsci13060548 Negative / Null Result ReportMedicine
Hijaze E, Razi T, Arbel R et al. · 2026 · Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
Objective To evaluate the diagnostic performance of BioPlex 2200 multiplex immunoassay (BI) for detecting antinuclear antibodies (ANA), compared with the gold standard, the indirect immunofluorescence assay (IIF), as a screening…
View details →DOI: 10.1097/rhu.0000000000002372 Negative / Null Result ReportMedicine
Tri PM, Hung NT, Liet DH et al. · 2026 · Emergency radiology
Purpose To assess the diagnostic performance of computed tomography (CT) for predicting main pancreatic duct injury in surgically explored patients with distal pancreatic trauma. Methods We conducted a prospective single-center diagnostic…
View details →DOI: 10.1007/s10140-026-02504-z Negative / Null Result ReportMedicine
Wei XT, Zhu LY, Wu YL et al. · 2026 · Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi
Objective: To evaluate the screening performance and related factors of ultrasound for hepatic steatosis in community-based elderly populations using controlled attenuation parameter (CAP) measured by transient elastography as the…
View details →DOI: 10.3760/cma.j.cn112338-20250626-00436 Negative / Null Result Report
TEZCE A, DURMUŞ E · 2026 · Preprint
Abstract Purpose The objective of this study is to compare the diagnostic efficacy of Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) in detecting lumbar spondylolysis among patients presenting with chronic low back pain, and…
View details →DOI: 10.21203/rs.3.rs-9247900/v1 Negative / Null Result Report
Livorsi DJ, Ritter S, Lund BC et al. · 2026 · Preprint
Abstract Background: The pneumococcal urinary antigen test can help rapidly identify Streptococcus pneumoniae as the cause of community-acquired pneumonia (CAP). In this study, we assessed the utility of this test across an integrated…
View details →DOI: 10.21203/rs.3.rs-9267869/v1 Negative / Null Result ReportOpen accessMedicine
Zorlutuna Kaymak N, Pekel İ, Demir Tekol S et al. · 2026 · BMC ophthalmology
Purpose To evaluate the diagnostic utility and real-world clinical impact of polymerase chain reaction (PCR) analysis of aqueous humor (AH) and vitreous samples in patients with uveitis including suspected infectious and mixed…
View details →DOI: 10.1186/s12886-026-05002-5 