Negative / Null Result Report
Suerink M, Hoffer M, Dingemans A et al. · 2026 · Preprint
Abstract Prenatal exome sequencing (pES) is challenging due to rapid turnaround requirements and limited phenotype information. Analysis strategies span gene panels through exome-wide review, with Artificial Intelligence (AI) as optional…
View details →DOI: 10.21203/rs.3.rs-9634215/v1 Negative / Null Result Report
von Oelreich E, Eriksson J, Arnason B et al. · 2026 · Preprint
Abstract Background Blunt and penetrating trauma differ in injury patterns, management, and outcomes, but data comparing early physiological and haemostatic responses within Scandinavian trauma systems remain limited. We aimed to…
View details →DOI: 10.21203/rs.3.rs-9969793/v1 Negative / Null Result ReportMedicine
Youssef MW, Perrin L, Denormandie AC et al. · 2026 · The French journal of urology
Purpose Ambulatory artificial urinary sphincter (AUS) implantation has been proposed as an alternative to conventional inpatient surgery, but comparative data remain limited. We aimed to compare early postoperative outcomes between…
View details →DOI: 10.1016/j.fjurol.2026.103135 Negative / Null Result Report
Sezici YL, Sabah GA · 2026 · Preprint
Abstract Background To evaluate and compare the performance of three artificial intelligence (AI) chatbots in generating responses to orthodontic retention-related questions in terms of clinical quality and readability. Methods A…
View details →DOI: 10.21203/rs.3.rs-9495119/v1 Negative / Null Result ReportMedicine
Yalçın S, Bostanoğlu Karaçin A, Aydın Ö et al. · 2026 · Respiratory medicine
Background In 2023, the European Academy of Allergy and Clinical Immunology (EAACI) proposed an immune response-based classification that integrates molecular, endotypic, and clinical characteristics to define predominant and co-occurring…
View details →DOI: 10.1016/j.rmed.2026.108961 Negative / Null Result ReportMedicine
Jinushi K, Saito T, Fujikawa K et al. · 2026 · Surgery today
Purposes Robotic gastrectomy (RG) offers superior dexterity and visualization compared with laparoscopic gastrectomy (LG). However, its high cost requires careful patient selection. This study aimed to evaluate whether these advantages…
View details →DOI: 10.1007/s00595-026-03292-2 Negative / Null Result ReportMedicine
Battal F, Kaya S, Kiraz HA · 2026 · Biomedicines
Background/Objectives : Hypericum perforatum L. (St. John's Wort) is extensively utilized in ethnopharmacology due to its anti-inflammatory and immunomodulatory properties. However, its effects on the interaction between innate immunity…
View details →DOI: 10.3390/biomedicines14061297 Negative / Null Result ReportMedicine
Doğan ÜK, Aslan S · 2026 · Scientific reports
The triglyceride-glucose (TyG) index has recently gained attention as a cost-effective and easily calculable surrogate marker reflecting insulin resistance-related metabolic risk. Given the close interplay between thyroid hormones, lipid…
View details →DOI: 10.1038/s41598-026-50447-9 Negative / Null Result ReportMedicine
Daoud J, Greenwood J, Botha T et al. · 2026 · Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists
ObjectiveTo evaluate confidence levels of junior doctors working in the paediatric emergency department (ED) in the assessment and management of acute mental health presentations.MethodsThis cross-sectional study invited 89 eligible junior…
View details →DOI: 10.1177/10398562261424122 Negative / Null Result Report
Edlinger M, Huber SE, Kogler ML et al. · 2026 · Preprint
Background Video games are increasingly recognised as promising tools for environmental education because of their potential to positively influence environmental attitudes and behaviours at scale. However, while effects of persuasive…
View details →DOI: 10.31234/osf.io/ghdva_v1 Negative / Null Result ReportMedicine
Gulec E, Turktan M, Hatipoglu Z et al. · 2026 · Medicine
Adult patients often experience preoperative anxiety that can influence their anesthetic requirements. We investigated the effect of a preoperative midazolam anxiolytic dose on intraoperative sevoflurane consumption. This prospective,…
View details →DOI: 10.1097/md.0000000000049474 Negative / Null Result ReportMedicine
O'Rourke J, Byrne M, Schroers G · 2026 · Western journal of nursing research
Background Artificial intelligence (AI), particularly generative and large language models, is being used in nursing education, practice, and scholarly writing. Generative AI applications have been specifically examined for their use in…
View details →DOI: 10.1177/01939459261451723 Negative / Null Result ReportMedicine
Jaghoub Q, Nacar E, Özdoğan A et al. · 2026 · Odontology
This study evaluated the initial effect of dental loupe use on the 3D accuracy of laminate veneer preparations performed by prosthodontic specialty residents under standardized in vitro conditions. Twenty-six residents completed two…
View details →DOI: 10.1007/s10266-026-01440-1 Negative / Null Result Report
Erim B, Aray Y, Binici Hİ et al. · 2026 · Preprint
Abstract Advanced glycation end products (AGEs) are bioactive compounds implicated in oxidative stress, inflammation, and the development of chronic diseases. Skin autofluorescence (SAF) is a validated, non-invasive technique used to…
View details →DOI: 10.21203/rs.3.rs-9794759/v1 Negative / Null Result ReportMedicine
Vlassenbroek R, Peeters D, Matthewman L et al. · 2026 · The Journal of small animal practice
Objectives To assess the incidence of associative immune-mediated haemolytic anaemia in dogs diagnosed with immune-mediated haemolytic anaemia and to evaluate whether performing diagnostic imaging, specifically thoracic radiographs and…
View details →DOI: 10.1111/jsap.70159 Negative / Null Result ReportMedicine
Tailor PD, Wang KY, Xu TT et al. · 2026 · Ophthalmic surgery, lasers & imaging retina
Background and objective This study aimed to characterize clinical characteristics and visual outcomes of patients with hemorrhagic choroidal detachments. Patients and methods Single-center retrospective case series of patients with…
View details →DOI: 10.3928/23258160-20260413-02 Negative / Null Result ReportMedicine
Saito Y, Kyoda Y, Nofuji S et al. · 2026 · International journal of urology : official journal of the Japanese Urological Association
Objectives No previous studies have directly compared pre- and postoperative pressure flow study (PFS) outcomes between transurethral resection of the prostate (TURP) and photoselective vaporization of the prostate using the GreenLight XPS…
View details →DOI: 10.1111/iju.70532 Negative / Null Result ReportMedicine
Wallig MA, Kabir MR, Han A et al. · 2026 · The Journal of the Acoustical Society of America
Quantitative ultrasound parameters offer effective tools to evaluate microstructural changes in liver tissue and noninvasively assess tissue health. We examined the relationship between steatotic liver disease severity, measured by the…
View details →DOI: 10.1121/10.0043904 Negative / Null Result ReportMedicine
Zaver HB, Reszczynski O, Singh A et al. · 2026 · Clinical and translational gastroenterology
Introduction Telehealth access is integral to digestive health care. This study examined demographic, insurance, and social determinants of health associated with missed telehealth appointments, with secondary comparisons with missed…
View details →DOI: 10.14309/ctg.0000000000001032 Negative / Null Result ReportMedicine
Seetapan K, Nobsathian S, Bullangpoti V et al. · 2026 · Environmental toxicology and chemistry
The fish embryo toxicity test is widely used as an alternative to conventional acute fish toxicity assays, but its ecological relevance may be limited when the model species is nonnative to the region of interest. Here, we evaluated rose…
View details →DOI: 10.1093/etojnl/vgag077 Negative / Null Result ReportMedicine
Loucas R, Loucas M, Müller R et al. · 2026 · Plastic and reconstructive surgery
Background Breast lipofilling is a commonly utilized method in plastic surgery for breast reconstruction and augmentation. However, the procedure is often limited by the unpredictable survival of fat grafts, leading to dissatisfied…
View details →DOI: 10.1097/prs.0000000000013135 Negative / Null Result Report
HOWARD G, CRETU C · 2026 · Preprint
Abstract This study examined differences in professional practice, teaching motivations, and self-efficacy beliefs between outdoor teachers (OT) and classroom-based teachers (TT) in Israeli elementary schools, addressing limited…
View details →DOI: 10.21203/rs.3.rs-9188152/v1 Negative / Null Result ReportMedicine
Yadav S, Kiran SP, Gurjar SK et al. · 2026 · Journal of minimal access surgery
Introduction Laparoscopic Heller's myotomy (LHM) with a partial fundoplication is the standard surgical therapy for achalasia cardia. However, the ideal gastric extension of the myotomy remains controversial, as it may influence both…
View details →DOI: 10.4103/jmas.jmas_534_25 Negative / Null Result ReportMedicine
Kadum F, Benko K, Batičić L et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Atrial fibrillation (AF) and atrial flutter are associated with significant morbidity. While electrical cardioversion (ECV) is a standard treatment for sinus rhythm restoration, early arrhythmia recurrence is…
View details →DOI: 10.3390/medicina62061130 Negative / Null Result ReportMedicine
Chao X, Liu X, Luo J et al. · 2026 · Ear and hearing
Objectives To evaluate cochlear nerve responsiveness to electrical stimulation in prelingually deafened adults with late cochlear implantation by analyzing electrically evoked compound action potentials (eCAPs), and to compare their neural…
View details →DOI: 10.1097/aud.0000000000001850 Negative / Null Result Report
Nakamura M, Iino K, Ozaki T et al. · 2026 · Preprint
Abstract Purpose Placental abruption has a high recurrence risk, but the timing of recurrence relative to the previous episode remains unclear. This study evaluated recurrence timing and compared recurrent and first-time placental…
View details →DOI: 10.21203/rs.3.rs-9504787/v1 Negative / Null Result ReportMedicine
Mattar YA, Refaat O, El-Makawi S et al. · 2026 · The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Background Family history and APOE ε4 carriage represent the strongest non-modifiable Alzheimer's disease (AD) risk factors after advancing age. Early identification of cognitive markers in individuals at risk is essential for effective…
View details →DOI: 10.1080/15622975.2026.2666647 Negative / Null Result ReportMedicine
Schwanitz von Keitz P, Liebau KH, Mittelmeier W et al. · 2026 · Children (Basel, Switzerland)
Background: Developmental dysplasia of the hip (DDH) is the most common congenital musculoskeletal disorder in newborns. Flexion-abduction orthoses are widely used in early treatment; however, in vivo data on their biomechanical load…
View details →DOI: 10.3390/children13060777 Negative / Null Result Report
Li P, Ge L, Liu Y et al. · 2026 · Preprint
Background: /Objectives: Frailty and postoperative symptom burden are prevalent in older adults undergoing colorectal cancer (CRC) surgery, but their temporal, within-person interplay remains unclear. We aimed to investigate this…
View details →DOI: 10.20944/preprints202606.0136.v1 Negative / Null Result ReportMedicine
Hansen BK, Sandefur EP, Garcia AR et al. · 2026 · The journal of knee surgery
Abstract Cyclops lesions are a common postoperative complication that occurs in up to 47% of patients after anterior cruciate ligament reconstruction (ACLR), often resulting in painful extension loss. While risk factors for cyclops lesions…
View details →DOI: 10.1055/a-2886-8022