A Multicenter Observational Study Evaluating Outcomes Associated With Antibiotic Combination Versus Monotherapy in Patients With Septic Shock
Gustav Torisson, MD, PhD; Martin Bruun Madsen, MD, PhD; Agnes Schmidt Davidsen, MD; Anders Perner, MD, PhD; Jeffrey Lipman, MD; Joel Dulhunty, PhD; Fredrik Sjövall, MD, PhD · 2021 · Critical Care Explorations
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Objectives:. To explore the association between antibiotic combination therapy and in-hospital mortality in patients with septic shock in two tertiary ICUs in different countries. Design:. Retrospective observational study. Setting:. ICUs of two tertiary hospitals, Royal Brisbane and Women’s Hospital, Brisbane, QLD, Australia, and Rigshospitalet, Copenhagen, Denmark. Patients:. Adult patients with antibiotic treatment greater than or equal to 72 hours and vasopressor therapy greater than or equal to 24 hours. Intervention:. Combination versus mono antibiotic therapy. Measurements and Main Resu
Abstract by Gustav Torisson, MD, PhD; Martin Bruun Madsen, MD, PhD; Agnes Schmidt Davidsen, MD; Anders Perner, MD, PhD; Jeffrey Lipman, MD; Joel Dulhunty, PhD; Fredrik Sjövall, MD, PhD, Critical Care Explorations (2021) — licensed CC BY 4.0.
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Metadata source: DOAJ · DOI 10.1097/cce.0000000000000383
