Negative / Null Result ReportMedicine
Yoshimura M, Sakamoto S, Nakanishi T et al. · 2026 · International journal of obstetric anesthesia
Background Intravenous dexmedetomidine may be given to reduce shivering and discomfort during cesarean delivery under neuraxial anesthesia. Dexmedetomidine lowers heart rate and blood pressure, reduces catecholamine release, may have a…
View details →DOI: 10.1016/j.ijoa.2026.104868 Negative / Null Result ReportMedicine
Hua SV, Roberto CA, Yam E et al. · 2026 · Appetite
Large portions contribute to excess consumption. We tested whether a portion size labeling intervention influenced consumers to select smaller lunch portions. Two cafés introduced a reduced-sized main course (half the original size and…
View details →DOI: 10.1016/j.appet.2026.108494 Negative / Null Result ReportMedicine
Jariyasakoolroj T, O'Connell K, MacDonald T et al. · 2026 · Resuscitation
Aim To examine the association between tracheal intubation (TI) attempts and chest compression (CC) pauses on chest compression fraction (CCF) during pediatric CPR across a network of emergency departments. Methods Prospective…
View details →DOI: 10.1016/j.resuscitation.2026.111018 Negative / Null Result ReportMedicine
Yang Q, Dave A, Clark RSB et al. · 2026 · Brain research
Background Short chain fatty acids (SCFAs) including acetate, produced by gut microbiota, are key signaling molecules and impact microglial maturation and metabolism. Microglia play a dual role in maintaining homeostasis and…
View details →DOI: 10.1016/j.brainres.2026.150217 Negative / Null Result ReportMedicine
Rozemeijer S, Dubois EA, de Grooth HJ et al. · 2026 · Intensive care medicine
Background Besides temperature management, there is currently no effective therapy to decrease the burden of post-cardiac arrest syndrome. The pleiotropic effects of vitamin C may improve clinical outcome. Purpose This trial investigated…
View details →DOI: 10.1007/s00134-026-08492-5 Negative / Null Result ReportMedicine
Arabia A, Muñoz P, Álvarez-Real S et al. · 2026 · Plant science : an international journal of experimental plant biology
Serotonin is a widely conserved signaling molecule essential for plant development and stress responses, but its role in fruit postharvest physiology remains largely unexplored. This study aimed to evaluate the effects of 100 μM exogenous…
View details →DOI: 10.1016/j.plantsci.2026.113003 Negative / Null Result ReportMedicine
Ko T, Sakai A, Nakano R et al. · 2026 · Digestive diseases and sciences
Background Post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis is a common complication, and its prevention remains challenging. Although aggressive infusion of lactated Ringer's solution (hereafter Lactated Ringer's)…
View details →DOI: 10.1007/s10620-026-09794-w Negative / Null Result Report
Freeman G, Rousseau A, Brunton M et al. · 2025 · Preprint
Abstract This study presents the findings on the use of narrative when communicating complex scientific uncertainties. A growing body of evidence in narrative cognition and communication has shown promise for the use of narrative in…
View details →DOI: 10.21203/rs.3.rs-7860451/v1 Negative / Null Result ReportMedicine
Roberts ET, Schmajuk G, Fitzpatrick J et al. · 2026 · Joint Commission journal on quality and patient safety
Background Metrics with acceptable reliability are necessary to ensure that quality measures reward performance. Low metric reliability may result from a lack of differences between reporting entities or low numbers of eligible patients.…
View details →DOI: 10.1016/j.jcjq.2026.01.008 Negative / Null Result ReportOpen accessMedicine
Pundi K, Frimodt-Møller EK, Soliman EZ et al. · 2025 · Open heart
Background Previous epidemiological studies demonstrated that premature atrial contractions (PACs) and premature ventricular contractions (PVCs) detected by single 12-lead ECGs can predict incident cardiovascular disease and death. The…
View details →DOI: 10.1136/openhrt-2025-003836 Negative / Null Result ReportOpen accessMedicine
Bokan J, Schmid JQ, Middelberg C et al. · 2026 · Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie
Purpose Large overjet increases the risk of traumatic dental injury (TDI). This study, part of the Münster Long-Term Study (MLS), aimed to investigate long-term changes in overjet with or without orthodontic treatment and to evaluate…
View details →DOI: 10.1007/s00056-025-00633-7 Negative / Null Result ReportMedicine
Moreira SE, Debs AL, de Oliveira EH et al. · 2026 · Brazilian journal of physical therapy
Background Diastasis recti abdominis (DRA) is a common postpartum condition that can persist for months, impair abdominal function, and negatively affect quality of life. Despite its prevalence, there is no gold standard treatment.…
View details →DOI: 10.1016/j.bjpt.2026.101584 Negative / Null Result ReportMedicine
Su M, Saxon-Filipe S, Ahn C et al. · 2025 · Clinical breast cancer
Background Metaplastic breast carcinoma (MpBC) is an aggressive subtype of breast cancer that is usually resistant to chemotherapy. Few studies have analyzed the role of immunotherapy and other treatments in early stage MpBC. We identified…
View details →DOI: 10.1016/j.clbc.2025.07.018 Negative / Null Result ReportMedicine
Narayan P · 2025 · Indian journal of thoracic and cardiovascular surgery
Dual antiplatelet therapy (DAPT) is recommended after acute coronary syndrome (ACS), but evidence in coronary artery bypass graft (CABG) patients is limited. The TACSI (Dual Antiplatelet Therapy with Ticagrelor and Acetylsalicylic Acid…
View details →DOI: 10.1007/s12055-025-02121-4 Negative / Null Result ReportMedicine
Marr J, Meyers DJ, Ryan AM · 2026 · Health affairs (Project Hope)
The Centers for Medicare and Medicaid Services (CMS) is increasingly experimenting with prior authorization in traditional Medicare. In 2016, CMS began using pre-claim review, a prior authorization-like system in which claims are reviewed…
View details →DOI: 10.1377/hlthaff.2025.01356 Negative / Null Result ReportMedicine
Liu S, Song X, Li D et al. · 2025 · Wetlands.
Constructed Wetland (CW) is a low-carbon, sustainable ecological treatment technology widely used for deep treatment of wastewater treatment plant tailwater. However, constrained by the lack of available carbon source in the tailwater, the…
Negative / Null Result ReportMedicine
Martínez-Ocón J, Pérez M, Calvo A et al. · 2026 · Journal of clinical anesthesia
Background Sedation during endoscopic retrograde cholangiopancreatography procedures (ERCP) increases the risk of hypoxemia and the need for respiratory support in high-risk patients. High flow nasal cannula (HFNC) provides humidified gas…
View details →DOI: 10.1016/j.jclinane.2026.112189 Negative / Null Result Report
Diener J, Krafft J, Rayling S et al. · 2025 · Preprint
The global rise in nursing home (NH) populations presents substantial challenges, as residents frequently experience physical and cognitive decline, low physical activity, and high fall risk. This study evaluated the effectiveness of the…
View details →DOI: 10.20944/preprints202511.1418.v1 Negative / Null Result Report
Linares LAR, Martinez RCR, Carvalho VH et al. · 2026 · Preprint
Abstract Background and Objectives: Pain control after cardiac surgery remains suboptimal, and concerns about neuraxial techniques under anticoagulation limit the use of thoracic epidurals. The erector spinae plane (ESP) block offers a…
View details →DOI: 10.21203/rs.3.rs-8308763/v1 Negative / Null Result ReportMedicine
Michaan N, Michaan N, Laskov I et al. · 2026 · Journal of lower genital tract disease
Objectives Cervical conization (loop electrosurgical excision procedure) under local anesthesia is often associated with anxiety and procedural pain. Virtual reality (VR) glasses may enhance patient experience and reduce discomfort during…
View details →DOI: 10.1097/lgt.0000000000000928 Negative / Null Result ReportMedicine
Butala AD, Nanayakkara S, Johnston R et al. · 2026 · The American journal of cardiology
Stroke is a serious complication following transcatheter aortic valve implantation, associated with increased disability and mortality. Despite this, there is a lack of patient-level data examining stroke in contemporary, lower-risk…
View details →DOI: 10.1016/j.amjcard.2026.03.005 Negative / Null Result ReportMedicine
Zhou Y, Dai C, Wu F et al. · 2026 · Pulmonology
Background Low-dose theophylline has anti-inflammatory effects, but its efficacy in mild to moderate COPD remains controversial. Research question Is low dose theophylline effective and safe in patients with mild to moderate COPD? Methods…
View details →DOI: 10.1080/25310429.2026.2652159 Negative / Null Result ReportMedicine
Geoffrion D, Mikhail D, Rizk M et al. · 2025 · Ocular immunology and inflammation
Authors reported an 18% rate of endophthalmitis in Boston type 1 keratoprosthesis (KPro) patients, higher than previously reported rates. Most cases occurred during the COVID-19 pandemic, likely due to reduced access to care. Bandage…
View details →DOI: 10.1080/09273948.2025.2583219 Negative / Null Result ReportOpen accessMedicine
Pacini GS, Manfro AG, Schuchmann RA et al. · 2026 · Clinical kidney journal
Background Percutaneous kidney allograft biopsy is essential for evaluating graft dysfunction, but post-procedural bleeding remains the most frequent complication, particularly among recipients with impaired renal function. Desmopressin…
View details →DOI: 10.1093/ckj/sfag083 Negative / Null Result ReportMedicine
Stelmashook EV, Genrikhs EE, Alexandrova OP et al. · 2025 · Biomeditsinskaia khimiia
Copper ions (Cu2+) at concentrations of 25-50 μM stimulate lipopolysaccharide (LPS)-induced nitric oxide (NO) production in glial cell cultures derived from rat cerebral cortex and containing both astrocytes and microglia. Addition of a…
View details →DOI: 10.18097/pbmcr1597 Negative / Null Result ReportMedicine
Hamaya R, Li S, Lau J et al. · 2026 · American journal of hypertension
Background Multivitamin-multimineral (MVM) supplements have been associated with lower blood pressure (BP) in several small trials. We investigated the effects of a MVM on incident hypertension and BP in a secondary analysis of the COcoa…
View details →DOI: 10.1093/ajh/hpaf224 Negative / Null Result Report
Li M, Liu L, Qin Y et al. · 2025 · Preprint
Abstract Purpose The relationship between moderate physical activity (MPA) and vigorous physical activity (VPA) concerning the risk of sarcopenia in adolescents remains unclear. We aimed to investigate the association between MPA, VPA, and…
View details →DOI: 10.21203/rs.3.rs-6299119/v1 Negative / Null Result ReportMedicine
Detelich J, Martin GS · 2025 · Annals of internal medicine
Clinical impact ratings Emergency Med: [Formula: see text] GIM/FP/GP: [Formula: see text] Critical Care: [Formula: see text].
View details →DOI: 10.7326/annals-25-00805-jc Negative / Null Result ReportMedicine
Dubrovsky L, Pushkarsky T, Brichacek B et al. · 2026 · Microorganisms
Trained immunity (TRIM) enhances innate immune responses through epigenetic and metabolic reprogramming but may become maladaptive, contributing to chronic inflammation. In people living with HIV (PLWH), maladaptive TRIM has been proposed…
View details →DOI: 10.3390/microorganisms14020355 Negative / Null Result ReportMedicine
Tamoto M, Kai S, Yoshida H et al. · 2026 · Journal of cardiothoracic and vascular anesthesia
Objectives To compare the real-world effectiveness of combined propofol and dexmedetomidine (PRODEX) sedation with propofol monotherapy on survival and postoperative delirium (POD) in a large nationwide cohort of patients undergoing…
View details →DOI: 10.1053/j.jvca.2025.11.037 