e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21300 results · page 360 of 710

Negative / Null Result ReportMedicine

Difference in outcomes between right and left posterior descending artery percutaneous coronary intervention: an Australian statewide registry analysis.

Rahman Zahin, Batchelor, Brennan et al. · 2026 · The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology

Percutaneous coronary intervention (PCI) is an important treatment for coronary artery disease, and coronary dominance may influence procedural risk. PCI to a left-sided posterior descending artery (L-PDA) occurs in the setting of…

View details →DOI: 10.1186/s43044-026-00755-2
Failed Experiment ReportMedicine

Survival Outcomes in Early Onset Appendiceal Adenocarcinoma (EOAA).

Gujarathi, Belmont, Rodman et al. · 2026 · Annals of surgical oncology

The incidence of early onset (age&#x2009;<&#x2009;50 years at diagnosis) appendiceal adenocarcinoma (EOAA) is rising alarmingly. Reported data on etiology, treatment, and outcomes is scarce. In this study, we report clinical outcomes for…

View details →DOI: 10.1245/s10434-026-19855-z
Failed Experiment ReportMedicine

Age-dependent alterations in anterior cingulate excitation-inhibition balance in major depressive disorder revealed by 7-Tesla magnetic resonance spectroscopy.

Yoshihara, Suwa, Kubota et al. · 2026 · NeuroImage. Clinical

Altered excitation-inhibition (E/I) balance has been implicated in the pathophysiology of major depressive disorder (MDD), but previous magnetic resonance spectroscopy (MRS) findings have been inconsistent, partly due to methodological…

View details →DOI: 10.1016/j.nicl.2026.104018
Negative / Null Result ReportMedicine

Glucose Metrics During School Hours in Primary School-Aged Children With Type 1 Diabetes: A Population-Based Cohort Study.

Paull, Connor, Smith et al. · 2026 · Journal of paediatrics and child health

School time represents a significant component of overall glycaemia for children with type 1 diabetes (T1D), and glucose levels during instructional time may be important for optimising academic progress. There is, however, limited…

View details →DOI: 10.1111/jpc.70463
Negative / Null Result ReportMedicine

The financial burden resulting from complementary and alternative medicine in oncology care.

Bagdonas, Sch&#xe4;fer, Wolf et al. · 2026 · BMC complementary medicine and therapies

Complementary and alternative medicine (CAM) is widely used by oncology patients to manage symptoms, reduce stress, and improve quality of life. Unlike conventional treatments, CAM is rarely reimbursed in Germany, resulting in significant…

View details →DOI: 10.1186/s12906-026-05417-z
Negative / Null Result ReportMedicine

Efficacy of a digitally designed anatomical repositioning splint for adolescent temporomandibular joint anterior disc displacement with reduction: a randomized controlled trial.

Wang, Wang, Wu et al. · 2026 · BMC oral health

Anterior disc displacement with reduction (ADDwR) is a common temporomandibular joint disorder in adolescents. Conventional anterior repositioning splints (ARS) often lack anatomical adaptation, which may limit their therapeutic precision…

View details →DOI: 10.1186/s12903-026-08753-1
Negative / Null Result ReportMedicine

Urologic outcomes in children with closed spinal dysraphism with and without untethering of the spinal cord.

Avellan, Pakkasj&#xe4;rvi, Palom&#xe4;ki et al. · 2026 · Journal of pediatric surgery

Closed spinal dysraphism (CSD) comprises a heterogeneous group of congenital anomalies that may remain asymptomatic or present with neurological and urological dysfunction. This study aimed to evaluate long-term urological outcomes in…

View details →DOI: 10.1016/j.jpedsurg.2026.163235
Negative / Null Result ReportMedicine

A TriNetX global collaborative network retrospective cohort study on the impact of COVID-19 vaccination on juvenile idiopathic arthritis.

Yong, Chiang, Yang et al. · 2026 · Scientific reports

The objective is to determine the Impact of COVID-19 Vaccination and Medical Utilization in Juvenile Idiopathic Arthritis (JIA) patients. Our study retrieved data from the US Collaborative Network in TriNetX between January 1st, 2020, and…

View details →DOI: 10.1038/s41598-026-52548-x
Negative / Null Result ReportMedicine

Does Tibial Tunnel Placement Affect Postoperative Function and Isokinetic Outcomes in Patients Undergoing Anatomical Single-Bundle Anterior Cruciate Ligament Reconstruction with Hamstring Autograft?

Arslanta&#x15f;, Deveci, Ozdemir et al. · 2026 · The journal of knee surgery

Tunnel malposition is a frequent complication of anterior cruciate ligament (ACL) reconstruction. We evaluated whether the tibial tunnel location of patients who underwent anatomical single-bundle ACL reconstruction with hamstring tendons…

View details →DOI: 10.1055/a-2886-7914
Negative / Null Result ReportMedicine

Comparison of early-onset and average-onset colorectal cancer in Saudi Arabia: A multicenter retrospective cohort study.

Alessy, Al-Bawardy, Alabdullah et al. · 2026 · Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

Although overall colorectal cancer (CRC) incidence has stabilized or declined in some regions, early-onset CRC (EO-CRC) is increasing in many countries. We aimed to compare EO-CRC with average-onset CRC (AO-CRC) to inform screening and…

View details →DOI: 10.4103/sjg.sjg_51_26
Negative / Null Result ReportMedicine

Thermal ablation versus hepatectomy in patients with liver metastases from RAS-mutated colorectal cancer.

Wen, Zhou, Chen et al. · 2026 · Journal of cancer research and therapeutics

To compare the efficacy and safety of thermal ablation therapy and hepatectomy in patients with RAS-mutated colorectal liver metastases (CRLMs). A 1:1 propensity score matching (PSM) analysis was conducted to categorize patients into…

View details →DOI: 10.4103/jcrt.jcrt_1515_25
Negative / Null Result ReportMedicine

Large Language Models and Metabolic Bariatric Surgery: A Pilot Concordance Study Between ChatGPT and Multidisciplinary Team Recommendations.

Ahmed, Bhanderi, Westerman et al. · 2026 · Obesity surgery

Operation selection in metabolic surgery is a complex decision making process led by a multidisciplinary team that integrates multiple anatomical, clinical, metabolic and psychosocial aspects. The ability of large language models (LLMs)…

View details →DOI: 10.1007/s11695-026-08777-0
Negative / Null Result ReportMedicine

Impact of Renal Artery Diameter and Bridging Stent Length on Renal Outcomes of Patients Treated by Multi-Branch Endovascular Aortic Repair.

Nunes, Theis, Gomes et al. · 2026 · Journal of vascular surgery

Branched endovascular aortic repair (BEVAR) has been increasingly utilized as a treatment option for thoracoabdominal aortic aneurysms (TAAAs), but risk of renal artery (RA) branch occlusion remains a concern. The aim of this study was to…

View details →DOI: 10.1016/j.jvs.2026.05.035
Negative / Null Result ReportMedicine

Masticatory Muscle Activity in a Group of Thai Children with Skeletal and Dental Malocclusions: A Pilot Study Using Surface Electromyography.

Saleechan, Pumklin, Puapichartdumrong et al. · 2026 · European journal of dentistry

This pilot study aimed to investigate masseter muscle (MM) and anterior temporal muscle activity, symmetry, synergy, and effort in Thai children with skeletal and dental malocclusions. Children aged 9 to 12 years were recruited ( N…

View details →DOI: 10.1055/s-0046-1820500
Negative / Null Result ReportMedicine

Contemporary management of paediatric acute mastoiditis in Aotearoa New Zealand.

Noakes, Stevenson, Bird et al. · 2026 · International journal of pediatric otorhinolaryngology

There has been a recent increase in the incidence of paediatric acute mastoiditis (AM) with a global trend towards more conservative management strategies. Our aim was to evaluate the contemporary management of paediatric AM in Aotearoa…

View details →DOI: 10.1016/j.ijporl.2026.112882
Negative / Null Result ReportMedicine

Extracorporeal Membrane Oxygenation Support Before Pediatric Heart Transplantation: A Comparison of Two Eras.

Bilgili, Abu-Mowis, Jeng et al. · 2026 · ASAIO journal (American Society for Artificial Internal Organs : 1992)

The United Network for Organ Sharing (UNOS) Database was studied to evaluate the state of extracorporeal membrane oxygenation (ECMO) utilization before pediatric heart transplantation and to compare outcomes over the last two decades. A…

View details →DOI: 10.1097/mat.0000000000002726
Negative / Null Result ReportMedicine

Effectiveness of Forum Play to promote respectful maternity care: A pilot intervention investigating self-reported perception and behaviour among care providers in urban Nepal.

Paudel Ghimire, Dahal, Joshi et al. · 2026 · PloS one

Ensuring respectful maternity care is crucial to promote positive childbirth experiences among women. Globally, 22-100% women report experiencing at least one form of disrespect and abuse during facility-based birth, with a study in Nepal…

View details →DOI: 10.1371/journal.pone.0349437
Negative / Null Result ReportMedicine

The Effect of Isotonic Versus Isometric Strength Exercise for Pain and Strength in Proximal Hamstring Tendinopathy: A Randomized Crossover Trial.

Rich, Ford, Cook et al. · 2026 · Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

The effect of isometric exercise on pain and strength for various tendinopathies has been investigated but there are no published studies on proximal hamstring tendinopathy (PHT). The objective of this trial was to determine the…

View details →DOI: 10.1097/jsm.0000000000001478
Negative / Null Result ReportMedicine

Multiparametric MRI-Based Habitat Radiomics Combined with Deep Transfer Learning for Predicting Extrathyroidal Extension in Papillary Thyroid Carcinoma.

Li, Zeng, Wang et al. · 2026 · Journal of imaging informatics in medicine

The objective of the study is to develop and validate a multiparametric MRI (mpMRI)-based model that integrated with habitat-based radiomics, deep transfer learning (DTL), and quantitative parameters for the preoperative prediction of…

View details →DOI: 10.1007/s10278-026-02011-0