e-ISSN: Pending
Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21300 results · page 353 of 710

Negative / Null Result Report

Profiles of Parental Self- and Child-Focused Emotion Regulation: Longitudinal Associations With Parental Exhaustion, Children’s Internalizing Problems, Children’s Achievement, and the Parent–Child Relationship

Jordan G, Stockinger K, Schiltz C et al. · 2025 · Preprint

Parenting is an emotion-eliciting experience that requires parents to navigate the dual demands of regulating their own and their children’s emotions. However, patterns of such self- and child-focused emotion regulation (ER) and their…

View details →DOI: 10.31234/osf.io/2u6nj_v1
Negative / Null Result Report

Long-Term Outcomes of Childhood ADHD Stimulant Use Trajectories

Plas Nvd, Noordermeer S, Hartman C et al. · 2025 · Preprint

Background. Stimulant medication is the first-line pharmacological treatment option for children with attention-deficit/hyperactivity disorder (ADHD). However, long-term effects remain unclear. Therefore, we explored long-term (>12 years)…

View details →DOI: 10.31234/osf.io/wjhtv_v1
Negative / Null Result ReportMedicine

Container Mosquito Abundance in Brooklyn Community Gardens.

Kelley AT, Boger R · 2025 · EcoHealth

Community gardens in urban Brooklyn, New York are social spaces that provide food sovereignty to many New Yorkers, but the arrival of the mosquito Aedes albopictus and longtime presence of Culex pipiens makes socializing in these spaces…

View details →DOI: 10.1007/s10393-025-01739-5
Negative / Null Result ReportMedicine

Polygenic Risk of New Onset Atrial Fibrillation in Nonischemic Cardiomyopathy.

Dababneh SF, Parker J, Ahmed R et al. · 2026 · JACC. Clinical electrophysiology

Background Polygenic risk scores for atrial fibrillation (AF) can predict lifetime and incident AF in healthy populations and patients with cardiovascular disease. Their clinical utility in predicting new onset atrial fibrillation (NOAF)…

View details →DOI: 10.1016/j.jacep.2026.01.024
Negative / Null Result ReportMedicine

Views of aging and symptoms of posttraumatic stress disorder among older adult war veterans in the context of renewed war.

Avidor S, Shenkman G, Shrira A et al. · 2026 · The journals of gerontology. Series B, Psychological sciences and social sciences

Objectives For aging combat veterans, experiencing renewed war in old age can exacerbate coping with age-related challenges. The present study sought to examine how past and current war-related stressors affect long-term trajectories of…

View details →DOI: 10.1093/geronb/gbaf226
Negative / Null Result ReportOpen accessMedicine

Psychological Distress and Bias-relevant Thinking During the Jharkhand Elections Among Young Voters.

Kumari A, Hasan K, Mirza AZ et al. · 2026 · Annals of neurosciences

Background Digital political campaigning in India has expanded rapidly, increasing the likelihood that young voters encounter election-related content routinely across social platforms and messaging groups. The Neurocognitive and mental…

View details →DOI: 10.1177/09727531261417818
Negative / Null Result ReportMedicine

Does earlier mobilization reduce venous thromboembolism after spine surgery?

Ng MK, Mathew J, Dalton J et al. · 2026 · European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society

PURPOSE: Venous thromboembolism (VTE) is an uncommon but potentially devastating complication following spine surgery. Although early mobilization is encouraged as a preventive measure, the influence of inpatient physical therapy on VTE…

View details →DOI: 10.1007/s00586-025-09714-y
Negative / Null Result ReportOpen accessMedicine

Childhood Linear Growth and Early Morbidity as Predictors of Adolescent Cognitive Ability in Malawi: A Prospective Observational Study.

Videman K, Leppänen JM, Hallamaa L et al. · 2026 · Acta paediatrica (Oslo, Norway : 1992)

Aim Growth faltering and loss of development potential are common in low- and middle-income countries. We aimed to study whether linear growth before and after 2 years, height-for-age Z-score (HAZ) from 1 month until 13 years and morbidity…

View details →DOI: 10.1111/apa.70369
Negative / Null Result Report

The time course of neural activity predictive of self-initiated movement

Jeay-Bizot L, Basbug M, Maoz U et al. · 2025 · Preprint

Decades of research have shown that early ramping activity is a very reliable antecedent of self-initiated movement. However, the dominant paradigm has been to only analyze data epochs culminating in movement, which discounts how often…

View details →DOI: 10.31234/osf.io/vdbg8_v1
Negative / Null Result Report

Does Previous Anaphylaxis Determine Differences Between Patients Undergoing Oral Food Challenges to Cow’s Milk and Hen’s Egg?

Klim L, Michalik M, Wąsowicz P et al. · 2025 · Preprint

Background: Oral food challenges (OFCs) are still the reference standard for confirming food allergy, yet the influence of previous anaphylaxis on challenge outcomes remains uncertain. Patients with a history of anaphylaxis are often…

View details →DOI: 10.20944/preprints202512.2132.v1
Negative / Null Result ReportMedicine

Transdermal Initiation of Buprenorphine Among Hospitalized Persons: A Retrospective Study.

Hathaway DB, Sato T, Szpak V et al. · 2026 · Journal of the Academy of Consultation-Liaison Psychiatry

Background Buprenorphine is an effective treatment for opioid use disorder but may be difficult to initiate among hospitalized patients due to concerns about acute pain and withdrawal risks. Objective We sought to evaluate the safety and…

View details →DOI: 10.1016/j.jaclp.2025.11.001
Negative / Null Result ReportMedicine

Throwing Load Does Not Affect Musculoskeletal Measures Around Competitive Pitching in Adolescent Baseball Pitchers.

Pexa BS, Giuliani-Dewig HK, Myers JB et al. · 2025 · Journal of athletic training

Context Baseball pitching load is linked to injury in adolescent baseball athletes; however, it is unclear if pitch counts are a good indicator of total upper extremity load during baseball pitching. Objectives The purpose of this study is…

View details →DOI: 10.4085/1062-6050-0052.25
Negative / Null Result Report

Developmental Relationship Between Home Literacy Environment and Emergent Literacy in a Transparent Orthography: A Two-Year Longitudinal Study in Japanese Preschoolers

Tanji T, Takahashi K, Matsushita H et al. · 2025 · Preprint

Abstract We examined the relationship between home literacy environment and early literacy acquisition in Japanese syllabic Hiragana and whether this relationship changes during the preschool years. One hundred five Japanese-speaking young…

View details →DOI: 10.21203/rs.3.rs-7583467/v1
Negative / Null Result ReportMedicine

Value of carbohydrate antigen 125 in pleural effusion from acute heart failure and its relationship with atrial fibrillation.

Pérez Pisón E, Llàcer P, Croset F et al. · 2026 · Medicina clinica

Introduction Pleural effusion (PE) is a frequent complication in acute heart failure (AHF), driven by hydrostatic pressure, impaired lymphatic drainage, and systemic inflammation. This study aimed to evaluate the association between…

View details →DOI: 10.1016/j.medcli.2025.107316
Negative / Null Result ReportMedicine

Association of QTc Dispersion with Mortality, Intensive Care Unit Admission, Intubation, and Hospital Stay Duration in Acute Methadone Poisoning.

Taherkhani A, Yeganegi H, Tavasol A et al. · 2026 · Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir

Objective The objective of this study is to investigate the prognostic significance of QTc dispersion (QTcd) in patients with acute methadone poisoning and its association with critical clinical outcomes, including mortality, Intensive…

View details →DOI: 10.5543/tkda.2025.69048
Negative / Null Result ReportMedicine

Serum zinc-α2-glycoprotein and renal dysfunction in the general population: evidence from a 13-year cohort study.

Enomoto M, Fukami A, Adachi H et al. · 2026 · Clinical and experimental nephrology

Background Zinc-α2-glycoprotein (ZAG) is an adipokine, which may act locally to regulate adipocyte metabolism. Downregulation of ZAG expression in obesity has been reported in obesity in both mice and humans. In contrast, other studies…

View details →DOI: 10.1007/s10157-025-02813-6
Negative / Null Result ReportMedicine

Systematic reexamination of early verb dominance: Verbal and nonverbal characteristics of caregiver input and their contribution to long-term language outcomes.

Kim M, Mun J, Kim G et al. · 2026 · Developmental psychology

Early language input to infants varies in lexical composition across languages and contexts. For instance, American-English input emphasizes nouns more than verbs, while Mandarin Chinese and Korean inputs provide more verbs than nouns, the…

View details →DOI: 10.1037/dev0002089
Negative / Null Result ReportMedicine

Testing Sentence-in-Noise Recognition With Synthetic Speech and Automatic Speech Recognition.

Calandruccio L, Weidman D, Leatherwood A et al. · 2025 · Journal of speech, language, and hearing research : JSLHR

Purpose Characterizing speech-in-noise recognition is fundamental to both clinical audiology and hearing research. Current methods rely on human speech recordings and human testers. However, modern artificial intelligence tools could…

View details →DOI: 10.1044/2025_jslhr-24-00893
Negative / Null Result ReportMedicine

Young athletes' social goals during the children-to-youth sport transition: A latent profile and latent transition analysis.

Jørgensen TM, Abrahamsen FE, Gjesdal S · 2026 · Journal of sports sciences

While the social aspect of sports is considered crucial for participation, the influence of social goals in motivating young athletes remains relatively unexplored. This study examined social goal profiles and their stability during…

View details →DOI: 10.1080/02640414.2025.2575416
Negative / Null Result ReportMedicine

Social attunement and alcohol use: The role of age and gender.

Romein C, Colyer-Patel K, Kroon E et al. · 2026 · Addictive behaviors

Background Alcohol use typically peaks during adolescence and early adulthood, when its social reinforcement value is high, and then decreases as individuals take on more adult-like responsibilities. The present study investigates whether…

View details →DOI: 10.1016/j.addbeh.2025.108587
Negative / Null Result ReportMedicine

Personality profiles and trauma history in ketamine therapy for mood and anxiety disorders: A latent profile analysis of short-term outcomes.

Gregoire N, Klukas E, Kaseweter K et al. · 2025 · Psychopharmacology

Rationale Ketamine-assisted therapy is emerging as a fast-acting intervention for treatment-resistant depression and anxiety. However, individual response to treatment varies, and little is known about how personality traits and trauma…

View details →DOI: 10.1007/s00213-025-06948-y
Negative / Null Result ReportMedicine

Can higher guy's scores predict increased complications? exploring the link with clavien-dindo classification.

Gul L, Ullah S, Yousuf SB et al. · 2025 · JPMA. The Journal of the Pakistan Medical Association

Objectives To determine the role of guy's stone score in predicting the complications rate for percutaneous nephrolithotomy. Methods The descriptive study was conducted at the Sindh Institute of Urology and Transplantation, Karachi, from…

View details →DOI: 10.47391/jpma.20571
Negative / Null Result ReportMedicine

Intravenous Bolus Fluid Therapy Versus No Fluid Therapy Prior to Pericardiocentesis in Dogs: A Randomized Controlled Trial in 30 Dogs.

Jones N, Humm K, Tinson EW · 2026 · Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)

Objective To determine the cardiovascular and respiratory effects of bolus IV isotonic crystalloid fluid therapy before pericardiocentesis in dogs with pericardial effusion. Design Prospective, randomized, nonblinded clinical trial…

View details →DOI: 10.1111/vec.70073
Negative / Null Result ReportMedicine

Hemolysis and Acute Kidney Injury Following Cardiac Surgery With Cardiopulmonary Bypass in Patients With Preexisting Renal Dysfunction.

Volleman C, Phelp PG, Dubelaar DPC et al. · 2026 · Journal of cardiothoracic and vascular anesthesia

Objectives Acute kidney injury (AKI) is a common complication following cardiac surgery with cardiopulmonary bypass (CPB). This study investigated whether cell-free hemoglobin (CFHb) levels after CPB are associated with endothelial damage…

View details →DOI: 10.1053/j.jvca.2026.02.039