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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21300 results · page 350 of 710

Negative / Null Result ReportOpen accessMedicine

Early stage adrenocortical carcinoma—what contributes to poor prognosis after adrenalectomy? A retrospective cohort study

Douk Kwon, C. Rah, Byung-Chang Kim et al. · 2024 · Annals of Surgical Treatment and Research

Purpose Adrenocortical carcinoma (ACC) is a rare primary carcinoma originating in the adrenal gland with a poor prognosis and a high recurrence rate. This study evaluated the risk factors associated with recurrence in patients with early…

View details →DOI: 10.4174/astr.2024.107.4.187
Negative / Null Result ReportMedicine

Dehorning Does Not Alter the Stress Response in Southern White Rhinoceroses (Ceratotherium simum simum) during Transport: A Preliminary Investigation

Anita Metzinger, Leith C. R. Meyer, P. Buss et al. · 2024 · Journal of Wildlife Diseases

Abstract: Translocation and dehorning are common and important practices for rhinoceros management and conservation. It is not known if dehorning causes a stress response or negatively affects rhinoceroses during transport. Twenty-three…

View details →DOI: 10.7589/jwd-d-23-00061
Negative / Null Result ReportOpen accessMedicine

Ventilation during continuous compressions or at 30:2 compression-to-ventilation ratio results in similar arterial oxygen and carbon dioxide levels in an experimental model of prolonged cardiac arrest

Jukka Kopra, E. Litonius, P. Pekkarinen et al. · 2023 · Intensive Care Medicine Experimental

Background In refractory out-of-hospital cardiac arrest, transportation to hospital with continuous chest compressions (CCC) from a chest compression device and ventilation with 100% oxygen through an advanced airway is common practice.…

View details →DOI: 10.1186/s40635-022-00485-0
Negative / Null Result ReportOpen accessMedicine

Does the Use of Nitroglycerin Patch Improve Local Anaesthetic Effects in Bier's Block? A Double-Blind Placebo Controlled Study

A. Elgebaly · 2018 · Anesthesiology Research and Practice

Aim The aim of the study was to assess the nitroglycerin patch as a new additive to Bier's block and its impact on the effects and dose of lidocaine. Methods Forty patients of each sex belonging to ASA I or II underwent elective tendon…

View details →DOI: 10.1155/2018/9674731
Negative / Null Result Report

DIALECTIC BEHAVIOUR THERAPYAND ASSERTIVENESS TRAINING IN MANAGING CHALLENGES OF MENTAL HEALTH AMONG ADOLESCENTS WHO ABUSE SUBSTANCES IN PORT-HARCOURT METROPOLIS

Kienka, Kienka, · 2026 · Journal of Professional Counselling

One of the rapidly growing global concerns today is the abuse of various substances that are linked with mental health with significant threat to the psychosocial challenges common in Nigeria. One of the pertinent problems is the…

View details →DOI: 10.61955/iopjof
Negative / Null Result ReportOpen accessPsychology

The Effects of a Structured and Unstructured Kindergarten Program on the Readiness Scores of Children in Selected Public Schools in Lafayette Parish, Louisiana.

Mary Coletta mcdonough Newkome · 1974

The major purpose of this study was to determine if there was a significant difference in readiness test scores between students who participated in a structured kindergarten program and those who participated in an unstructured program.…

View details →DOI: 10.31390/gradschool_disstheses.2684
Negative / Null Result ReportOpen accessMedicine

Evaluation of the Effectiveness and Safety of a Multifaceted Computerized Antimicrobial Stewardship Intervention in Surgical Settings: A Single-center Cluster-randomized Controlled Trial.

Xin Yuan, Kai Chen, Jing Yuan et al. · 2023 · International Journal of Antimicrobial Agents

BACKGROUND Inappropriate antimicrobial use is common for patients undergoing surgery. Whether a multifaceted computerized antimicrobial stewardship program is effective and safe in reducing inappropriate antimicrobial use in surgical…

View details →DOI: 10.1016/j.ijantimicag.2023.106787
Negative / Null Result ReportOpen accessBiology

Effects of new polymorphisms in the bovine myocyte enhancer factor 2D (MEF2D) gene on the expression rates of the longissimus dorsi muscle

E. Juszczuk-Kubiak, R. Starzyński, T. Sakowski et al. · 2012 · Molecular Biology Reports

Myocyte enhancer factor 2D (MEF2D), a product of the MEF2D gene, belongs to the myocyte enhancer factor 2 (MEF2) protein family which is involved in vertebrate skeletal muscle development and differentiation during myogenesis. The aim of…

View details →DOI: 10.1007/s11033-012-1689-6
Negative / Null Result ReportOpen accessChemistry

Trehalose may prevent postsurgical adhesions in a rabbit model of hysterotomy.

H. Fujino, Soojung Lee, Shigeki Suzuki et al. · 2011 · Journal of Veterinary Medical Science

The adhesion-preventing effect of trehalose in visceral organs was evaluated in a rabbit model. All rabbits underwent a hysterotomy, during which mild abrasion and desiccation was induced on the surfaces of visceral organs. In the control…

View details →DOI: 10.1292/jvms.10-0342
Negative / Null Result ReportOpen accessMedicine

Physical activity-related injuries of college students in southern China: A 1-year prospective study

Dongchun Tang, Weicong Cai, Yang Gao et al. · 2020 · Scientific Reports

This prospective study was to describe the incidence and characteristics of physical activity-related injuries (PARI) among college students in southern China. Online questionnaires and telephone interviews were combined to investigate the…

View details →DOI: 10.1038/s41598-020-64317-5
Negative / Null Result ReportOpen accessMedicine

Medical management in locally advanced and metastatic prostate cancer: Does changes in treatment policy have any specific effect on PSA levels?

M. Bağcıoğlu, C. Surcel, S. Ozcan et al. · 2017 · Archivio Italiano di Urologia e Andrologia

OBJECTIVE Androgen deprivation therapy (ADT) is commonly used as a first-line treatment for locally advanced and metastatic prostatic cancer (Pca). There is no consensus about which alternative treatment should be used after the failure of…

View details →DOI: 10.4081/aiua.2017.4.282
Negative / Null Result ReportOpen accessMedicine

No difference in anti-spike antibody and surrogate viral neutralization following SARS-CoV-2 booster vaccination in persons with HIV compared to controls (CO-HIV Study)

Kendall Kling, Patrick Janulis, A. Demonbreun et al. · 2023 · Frontiers in Immunology

Background Understanding the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination will enable accurate counseling and inform evolving vaccination strategies. Little is known about antibody response…

View details →DOI: 10.3389/fimmu.2022.1048776
Negative / Null Result ReportMedicine

Factors affecting long-term prognosis in adult patients with psychogenic non-epileptic seizures.

Turksever Meliha, Guldiken Baburhan, Ozkan Hulya et al. · 2024 · Ideggyógyászati Szemle

Background and purpose Among epileptic patients who are monitored using the video-electroencephalography monitoring (VEM) technique, in some patients a psychogenic non-epileptic seizure (PNES) can be identified as a definitive diagnosis.…

View details →DOI: 10.18071/isz.77.0021
Negative / Null Result ReportOpen accessBiology

Maximal COX-2 and ppRb expression in neurons occurs during early Braak stages prior to the maximal activation of astrocytes and microglia in Alzheimer's disease

J. Hoozemans, E. S. van Haastert, Robert Veerhuis et al. · 2005 · Journal of Neuroinflammation

Neuronal expression of cyclooxygenase-2 (COX-2) and cell cycle proteins is suggested to contribute to neurodegeneration during Alzheimer's disease (AD). The stimulus that induces COX-2 and cell cycle protein expression in AD is still…

View details →DOI: 10.1186/1742-2094-2-27
Negative / Null Result ReportMedicine

Metabolic and Nutritional Outcomes After Sleeve Gastrostomy and Gastric Bypass in Adolescents: A Cohort Study with 1-Year Follow-Up

Faraneh Zolfaghari, M. Barzin, M. Mahdavi et al. · 2025 · Hormone and Metabolic Research

Abstract We conducted this study to compare the anthropometric and metabolic outcomes and nutritional status, after sleeve gastrostomy (SG) and gastric bypass (GB) in adolescents with severe obesity. We selected 219 adolescents with severe…

View details →DOI: 10.1055/a-2679-9676
Negative / Null Result ReportOpen accessMedicine

Open simple prostatectomy and robotic simple prostatectomy for large benign prostatic hyperplasia: Comparison of safety and efficacy

J. Cho, K. T. Moon, J. Lee et al. · 2021 · Prostate International

Background To compare the safety and efficacy of open simple prostatectomy (OSP) and robotic simple prostatectomy (RSP) for the treatment of large benign prostatic hyperplasia (BPH). Materials and methods We retrospectively reviewed the…

View details →DOI: 10.1016/j.prnil.2020.11.004
Negative / Null Result ReportMedicine

Obesity and meningioma: a US population-based study paired with analysis of a multi-institutional cohort.

R. Khazanchi, K. Nandoliya, Maryam N. Shahin et al. · 2024 · Journal of Neurosurgery

OBJECTIVE Whether obesity is associated with meningioma and the impact of obesity by gender has been debated. The primary objective of this study was to investigate differences in BMI between male and female patients undergoing craniotomy…

View details →DOI: 10.3171/2023.11.jns23732
Negative / Null Result Report

Pemberian POC Urine Ternak Berbeda Konsentrasi Terhadap Pertumbuhan dan Serapan Kalium Tanaman Jagung Manis (Zea Mays L.)

Dhanu Pangestu Anggi Dinata, Anis Sholihah · 2024 · Folium : Jurnal Ilmu Pertanian

Livestock urine is one of the potential raw materials for for making potential liquid organic fertilizer (POC). Livestock urine contains various important nutrients, such as nitrogen, phosphorus, and potassium. Research This research was…

View details →DOI: 10.33474/folium.v8i2.22351
Negative / Null Result Report

Relationship Between Work-life Balance and Quality of Life among Millennials and Generation Z: a Correlation and Independent T Test Study

Nachaal S, M. R, Kavyaprabha N · 2026 · International Journal For Multidisciplinary Research

The present study aimed to investigate the relationship between Work-Life Balance (WLB) and Quality of Life (QOL) among Millennials and Generation Z employees through a quantitative correlational research design. To achieve this purpose,…

View details →DOI: 10.36948/ijfmr.2026.v08i02.74785
Negative / Null Result ReportMedicine

Safety and efficacy of anifrolumab therapy in systemic lupus erythematosus in real-world clinical practice: LOOPS registry.

Y. Miyazaki, M. Funada, S. Nakayamada et al. · 2023 · Rheumatology

OBJECTIVES To determine the safety and efficacy of anifrolumab in patients with systemic lupus erythematosus (SLE) classified based on the Lupus Low Disease Activity State (LLDAS) in real-world clinical practice. METHODS This retrospective…

View details →DOI: 10.1093/rheumatology/kead568
Negative / Null Result ReportOpen accessComputer Science

Smart learning environments for a smart city: from the perspective of lifelong and lifewide learning

Rongxia Zhuang, Haiguang Fang, Yan Zhang et al. · 2017 · Smart Learning Environments

In the perspective of lifelong learning, lifewide learning and learning society, learning environments have expanded from schools to a more broader space, and even to the whole city. School, family, community, workplace, and museum can be…

View details →DOI: 10.1186/s40561-017-0044-8
Negative / Null Result ReportOpen accessComputer Science

Utilizing the Blackboard Learning Management System at the University of Ha’il from the Perspective of Faculty Members using Internet Of Things (IOT)

A. Ali, Khaled Mohammad Abu Sheirah · 2021 · International Journal of Education and Information Technologies

The study aims to investigate the perceptions of faculty members in the preparatory year at the University of Ha’il concerning the use of the Blackboard learning management system, and to identify the impact of the study variables (gender,…

View details →DOI: 10.46300/9109.2020.14.23
Negative / Null Result ReportMedicine

Validation of a freely distributable software for the analysis of electrophysiological signals: Smart Tools for Evoked Potentials (STEP)

Kelly Cristina Lira de Andrade, Aline Tenório Lins Carnaúba, C. Batista et al. · 2025 · International Symposium on Cooperative Database Systems for Advanced Applications

ABSTRACT Purpose This study aimed to validate the STEP, an application developed for the analysis of various auditory and vestibular electrophysiological signals. The STEP was designed to enhance the accuracy and efficiency of latency and…

View details →DOI: 10.1590/2317-1782/e20240265en
Negative / Null Result ReportOpen access

Utility of ST2 soluble biomarker in patients with atrial fibrillation and pulmonary veins isolation

L. González-Melchor, J. García-Seara, J. Martinez-Sande et al. · 2023 · Europace

Abstract Funding Acknowledgements Type of funding sources: Public hospital(s). Main funding source(s): No fundings related Background Atrial fibrillation (AF) is the more frequent arrhythmia in clinical practice and the efficacy of…

View details →DOI: 10.1093/europace/euad122.162
Negative / Null Result ReportOpen accessMedicine

Comparative effects of cilazapril, carvedilol and their combination in preventing from left ventricular remodelling after acute myocardial infarction in rats.

Yuejin Yang, Yida Tang, Y. Ruan et al. · 2002 · Journal of the Renin-Angiotensin-Aldosterone System

OBJECTIVES To compare the effects of cilazapril, carvedilol and their combination in preventing left ventricular remodelling (LVRM) after acute myocardial infarction (AMI) in rats. METHODS Twenty-four hours after left coronary artery…

View details →DOI: 10.3317/jraas.2002.005
Negative / Null Result ReportOpen accessMedicine

Asymmetry of Lacunae between Brain Hemispheres Is Associated with Atherosclerotic Occlusions of Middle Cerebral Artery

Lingshan Wu, Hao Huang, Zhi-yuan Yu et al. · 2023 · Brain Science

Cerebral small vessel disease (CSVD) commonly coexists with intracranial atherosclerotic stenosis (ICAS). Previous studies have tried to evaluate the relationship between ICAS and CSVD; however, they have yielded varied conclusions.…

View details →DOI: 10.3390/brainsci13071016
Negative / Null Result Report

An evaluation and comparison of frictional resistance, surface roughness, and microbial colonization of silver-coated and uncoated stainless steel archwires – An in vivo study

Rutvi Vikram Raval, Padmaja Sharma, Harshit Naik et al. · 2024 · APOS Trends in Orthodontics

When undergoing fixed orthodontic treatment, white spot lesions and caries are frequently observed. The silver coating on brackets, archwires, and bands can help prevent these conditions. However, this might have an impact on friction and…

View details →DOI: 10.25259/apos_83_2024