A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21300 results · page 349 of 710
Kent T, Lewis G, Lewis G · 2025 · Preprint
Purpose: Sexual minority and trans individuals are at increased risk of suicidal behaviour comparedwith their heterosexual and cisgender counterparts. A potential explanation for this disparity is theconcept of minority stress. The present…
Zeng J, Huang D, Zhu M et al. · 2025 · Medicine
Weekend catch-up sleep (WCS) is a behavioral strategy employed to compensate for weekday sleep loss and has been reported to be associated with various metabolic outcomes. However, its association with obesity remains controversial. This…
Subramanian G, Zelano C, Paller KA et al. · 2025 · Preprint
Abstract Reactivation of recently acquired memories during sleep supports their longevity. Reactivation can be altered during sleep using odors or sounds through a technique termed targeted memory reactivation (TMR). Here, we attempted to…
Martin E, Conway CJ · 2026 · Ecology and evolution
Aggregation is common across taxa and typically confers clear benefits to group members (e.g., allo-parenting, group defense, thermoregulation, access to resources). But aggregation can also be costly. The mechanisms that underpin…
Huchegowda R, Harbishettar V, Sinha P et al. · 2025 · Preprint
Background Cognitive impairment in the older adult population has been linked to low Vitamin B12 levels and elevated Homocysteine levels, but evidence is not clear. This study examines the relationship between serum Vitamin B12 (B12)…
Danböck SK, Hettegger S, Franke LK et al. · 2025 · Preprint
Background: Peritraumatic dissociation is thought to contribute to posttraumatic symptoms like intrusions and memory disturbances. However, trauma-analogue studies that examined effects of experimental dissociation-induction on intrusions…
Ilkovska B, Trifunova BK, Ilkovski F et al. · 2025 · Preprint
Abstract Background: Breast cancer (BC) is one of the most common malignancies among women worldwide, with approximately 2.3 million new cases and 685,000 deaths reported in 2020. Inflammation-related hematologic parameters—such as the…
Malmagro R, García‐Navas V, Priyadarshana TS et al. · 2025 · Global Ecology and Biogeography
AIM: Historical and contemporary environmental factors are hypothesised to influence the degree of ecological specialisation of species. Long‐term climate stability might facilitate specialisation by promoting stable environments and…
Labbani-Motlagh Z, Nozarian Z, Haghi Ashtiani MT et al. · 2025 · Iranian journal of immunology : IJI
Background Coronavirus Disease 2019 (COVID-19) typically manifests with milder symptoms and lower mortality rates in children when compared to adults. Objective To investigate potential mechanisms underlying this age-related protection, we…
Bahmani A, Kemmerly T, Yang BE · 2026 · ACG case reports journal
Esophageal lichen planus (ELP) is a rare inflammatory disorder frequently misdiagnosed due to its nonspecific symptoms and overlapping features with other esophageal conditions. We present 3 cases of ELP characterized by delayed diagnosis…
Komai T · 2025 · Zootaxa
A new pagurid hermit crab species, Pagurus inflatus sp. nov., has been provisionally assigned to the heterogeneous genus Pagurus Fabricius, 1775. This new species is characteristic in its elongated right cheliped with a noticeably inflated…
Petrini S, Martucciello A, Righi C et al. · 2025 · Vaccine: X
Bovine alphaherpesvirus 1 (BoAHV-1) is a major cattle pathogen that causes infectious bovine rhinotracheitis (IBR) and other respiratory and reproductive disorders, resulting in substantial global economic losses to the cattle industry.…
Su J, Zhang WB, Sun B et al. · 2025 · Experimental & applied acarology
Haemaphysalis flava Neumann, 1897 is recognized as a vector for Dabie bandavirus (severe fever with thrombocytopenia syndrome virus, SFTSV), which is the etiological agent of severe fever with thrombocytopenia syndrome (SFTS). The tick…
Edsor E, Jose M, Sajesh S et al. · 2025 · Journal of pharmacy & bioallied sciences
Background The aim of this study is to assess whether there is a difference in the wound healing process following the extraction of a tooth between type 2 diabetes patients on oral hypoglycemic medications and nondiabetic patients.…
Del Rivero J, Donahue RN, Marte JL et al. · 2025 · The oncologist
Background It has been hypothesized that sequencing antigen-directed immunotherapy with immune checkpoint inhibitors could prime a tumor for immune response to immune checkpoint inhibitors. Methods This study (NCT03072160) was designed to…
Andersen Z, Kilgore S, Waite-Cusic J et al. · 2025 · Journal of dairy science
Hispanic-style cheeses (HSC), particularly fresh soft varieties, have been associated with numerous outbreaks of Listeria monocytogenes, highlighting the need to identify product characteristics or interventions that could mitigate L.…
Bybee SG, Clayton JL, Aruscavage N et al. · 2025 · The Gerontologist
Background and objectives Persons living with dementia often rely upon a care partner as their surrogate medical decision maker, yet little is known about how dementia care dyads achieve advance care planning (ACP) concordance: when a care…
Achilles S, Tomczak JN, Baumann FS et al. · 2025 · American journal of physiology. Gastrointestinal and liver physiology
DRA (Downregulated in adenoma, SLC26A3) is a major apical intestinal Cl - /HCO 3 - exchanger, which is expressed in complex and hybrid N -glycosylated forms. Although the importance of N -glycosylation is evident from the significantly…
Kostrna J, Astudillo A, Perez E · 2025 · Research quarterly for exercise and sport
Extensive research supports the positive effects of stretching on joint flexibility. During stretching, an individual's perceptions of stretch-related discomfort and pain negatively influence affective response. This study examined the…
Tian P, Fan M, Huang C · 2026 · Frontiers in medicine
Background Piperacillin-tazobactam is a widely used antibiotic. Although rare, thrombocytopenia related to piperacillin-tazobactam can be clinically significant. Drug-induced immune thrombocytopenia (DIIT) is difficult to distinguish from…
Erdoğan Ş, Tavat BC · 2025 · Physiology & behavior
Previous studies have suggested that time perception fluctuates throughout the day in relation to daily fluctuations of body temperature, and that there is a negative relationship between body temperature and time perception. The aim of…
Necker-Brown A, Mostafa MM, Georgescu A et al. · 2025 · Preprint
Transcription factors of the interferon regulatory factor (IRF) family play key roles during viral and bacterial infections. However, IRF regulation by inflammatory cytokines, including interleukin (IL)-1β and tumor necrosis factor (TNF)…
Yin CY, Vilai P, Thoreson AR et al. · 2026 · The Journal of hand surgery
Purpose Radial lengthening has been clinically proposed as an alternative treatment for distal radioulnar joint (DRUJ) instability associated with distal radius fractures based on the hypothesis that it functions in a manner similar to…
O’Brien C, Simon O, Franklin S et al. · 2025 · Preprint
Background: : Physical restraint of horses for veterinary procedures is necessary to allow completion of tasks effectively and without injury to patient or personnel. Objectives: : Comparison of physiological effects and behavioural…
Cinque K, Deere D, Veal C et al. · 2025 · Environmental management
The major drinking water reservoirs and catchments supplying many of Australia's capital cities have been protected from significant levels of public access since their construction (up to 140 years ago). In addition to the primary…
Xiong GL, Iosif AM, Gonzalez AD et al. · 2025 · Journal of the American Medical Directors Association
Objective Comparison of asynchronous telepsychiatry (ATP) with traditional synchronous telepsychiatry (STP) in skilled nursing facilities (SNFs) in California, United States. Design Patient-level randomized, controlled noninferiority…
Rezazadeh F, Lavaee F, Dezhkameh S et al. · 2025 · Preprint
Abstract Background: Lichen planus (LP), an inflammatory and chronic disorder, is immune-mediated and influences nails, skin, hair, and mucosal tissues. Autoimmune diseases affect females more commonly, and it is reported that there is an…
So R, Kariyama K, Oyamada S et al. · 2024 · Preprint
Objective To evaluate the effectiveness of screening and ultra-brief intervention (Ultra-BI) delivered by primary care physicians in less than 1 minute compared to simplified assessment only (SAO) for reducing alcohol consumption among…
Oliveira AHA, Paula DM, Serafini S et al. · 2026 · Acta cirurgica brasileira
Purpose To evaluate the effects of direct and remote ischemic preconditioning and postconditioning on kidney ischemia-reperfusion injury in young rats. Methods This study was divided into two experimental phases: preconditioning and…
Kesgin YM, Kaan AZ, Arslan M et al. · 2025 · World journal of emergency surgery : WJES
Background Textbook outcome (TO) is a concept that describes achieving an uneventful course for a patient undergoing surgery. It was first described for colorectal surgery and is now increasingly linked to various topics of surgical…