The mitochondrial-targeted antioxidant SkQ1 prevents mitochondrial-linked apoptosis but not necroptosis or skeletal muscle atrophy in ovarian cancer
Khajehzadehshoushtar S; Delfinis LJ; Rahman FA; Garibotti MC; Gandhi S; Brahmbhatt AN; Morris BA; Garlisi B · 2024 · Preprint
WASTE classifies this as Failed Experiment Report · AI classification, approximate
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Abstract (excerpt)
The degree to which mitochondrial-linked cell death pathways contribute to skeletal muscle atrophy during cancer remain unknown. Here, we combined a novel and robust mouse model of metastatic ovarian cancer with chronic administration of…
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Metadata source: Europe PMC · DOI 10.1101/2024.10.22.617245