Negative / Null Result ReportMedicine
De S Ferreira JM, Rodrigues HP, Alba HDR et al. · 2026 · Animal : an international journal of animal bioscience
High-concentrate diets supplemented with rumen-protected fats are widely used in feedlot lamb systems to improve energy supply and performance; however, the metabolic efficacy of these lipid sources may depend on the availability of…
View details →DOI: 10.1016/j.animal.2026.101869 Negative / Null Result Report
Hanson M, Pitcher D · 2025 · Preprint
Understanding the behaviour and emotions of other people is predicated on accurately decoding nonverbal facial cues. In the current study, we investigated whether the ensemble encoding of these facial cues is processed differently between…
View details →DOI: 10.64898/2025.12.04.692417 Negative / Null Result ReportMedicine
· 2025 · Nephron
In the article "Immunosuppressant Agents as Add-On Therapy Failed to Improve the Outcome of Immunoglobulin A Nephropathy with Crescent Score C1" [Nephron. 2024;148:587-600; https://doi.org/10.1159/000534788] by Bi et al., the funding grant…
View details →DOI: 10.1159/000548396 Negative / Null Result Report
Santos RdS, Gazzola MG, Figueira PM et al. · 2026 · Preprint
Abstract Background Despite rapid advances in large language models (LLMs), automated ICD-10 coding of real-world clinical narratives remains unreliable. A key challenge lies not only in model limitations, but in the intrinsic ambiguity of…
View details →DOI: 10.21203/rs.3.rs-8712058/v1 Negative / Null Result ReportMedicine
Ngeve SM, Khoury AL, Long JM · 2026 · Journal of visualized experiments : JoVE
Vanishing Lung Syndrome (VLS) is a rare, severe form of bullous pulmonary disease characterized by giant bullae occupying more than 30% of the hemithorax, which can easily be misdiagnosed as a pneumothorax. While cigarette smoking is the…
View details →DOI: 10.3791/68578 Negative / Null Result ReportMedicine
Stahl M, Zeidan AM · 2026 · Blood
Abstract Aside from allogeneic transplantation, the current standard-of-care approach for higher-risk myelodysplastic syndromes/neoplasms (HR-MDS) remains monotherapy with a hypomethylating agent (HMA), including azacitidine, decitabine,…
View details →DOI: 10.1182/blood.2025029727 Negative / Null Result ReportMedicine
Matsushita H, Oba K, Kurono K et al. · 2026 · Shock (Augusta, Ga.)
Introduction In cardiogenic shock (CS), persistent microcirculatory impairment despite improved macrocirculatory parameters is associated with poor outcomes. Therapeutic strategies must therefore address both macro- and micro-circulation.…
View details →DOI: 10.1097/shk.0000000000002842 Negative / Null Result ReportMedicine
Florens N · 2026 · Nephrologie & therapeutique
Cardiovascular mortality among hemodialysis patients remains strikingly high—around 10% per year—despite substantial advances in dialysis technology and medical care. Historically, several strategies extrapolated from the general…
View details →DOI: 10.1684/ndt.2026.156 Negative / Null Result ReportMedicine
Sekiguchi Y, Tsutsumi H, Kudo M et al. · 2026 · Gan to kagaku ryoho. Cancer & chemotherapy
84-year-old male was diagnosed with diffuse large B-cell lymphoma.He had Stage Ⅳ, performance status was 2, and 'high risk' according to the International Prognostic Index.He was started on Pola-R-mini-CHP.The day after completion of the 4…
Negative / Null Result ReportMedicine
Al Hindawi MA, Omran NE, Mostafa MH et al. · 2026 · European journal of pharmacology
In metastatic melanoma with a BRAF V600 mutation, inhibitors of BRAF and MEK have improved survival. Resistance may be acquired through late genetic alterations that restore mitogen-activated protein kinase (MAPK) signaling. Resistance can…
View details →DOI: 10.1016/j.ejphar.2026.178679 Negative / Null Result ReportMedicine
Chen H, Wang J, Fan C et al. · 2026 · Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
Background and aim The benefit of combining linaclotide with polyethylene glycol (PEG) for improving bowel preparation quality and adenoma detection in patients at risk for inadequate bowel preparation remains uncertain. This study aimed…
View details →DOI: 10.1016/j.dld.2026.01.229 Replication FailureMedicine
Xu K, Zhang R, Yuan Y et al. · 2026 · European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Aims Gallbladder carcinoma (GBC) has a poor prognosis, with lymph node metastasis (LNM) being a key prognostic factor. Controversies remain regarding lymph node dissection (LND) utility and prognostic differences of direct (DGBC) vs.…
View details →DOI: 10.1016/j.ejso.2026.111460 Null DatasetMedicine
Li A, Liu C, Xing R et al. · 2026 · Carbohydrate research
Phenol-sulfuric acid method, a classical approach for total sugar quantification, suffers from substantial variation in the colorimetric efficiency among different monosaccharides, which may result in significant measurement bias. In this…
View details →DOI: 10.1016/j.carres.2026.109835 Replication FailureMedicine
August D, Marsh N, Hall S et al. · 2026 · The Journal of perinatal & neonatal nursing
Purpose Implement and evaluate near-infrared (NIR) huddles for neonatal peripheral intravenous catheter (PIVC) insertion. Methods An implementation project investigated PIVC insertion attempts, site, inserter designation, dwell, and…
View details →DOI: 10.1097/jpn.0000000000000877 Negative / Null Result ReportMedicine
Huang JQ, Xiao HM, Ma CX et al. · 2026 · Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
To compare survival outcomes and safety between concurrent chemoradiotherapy (CCRT) and CCRT with concurrent immune checkpoint inhibitor (ICI) in patients with locally advanced esophageal squamous cell carcinoma. This multicenter cohort…
View details →DOI: 10.1093/dote/doag007 Negative / Null Result ReportMedicine
Moura RP, Mwema A, Bottemanne P et al. · 2026 · Journal of controlled release : official journal of the Controlled Release Society
Multiple sclerosis (MS) is a chronic neuroinflammatory disease affecting over 2.5 million people worldwide. Despite available therapies, no current treatment halts disease progression or specifically targets remyelination. Here, we…
View details →DOI: 10.1016/j.jconrel.2026.114804 Negative / Null Result ReportMedicine
Wu F, Wu R, Chen L et al. · 2026 · New biotechnology
Enhancing enzyme thermostability is crucial for industrial applications requiring robust performance under extreme conditions. Structure-based protein design models excel at improving thermal stability but often compromise enzymatic…
View details →DOI: 10.1016/j.nbt.2026.01.009 Negative / Null Result ReportMedicine
Liu X, Wang Y, Medina AA et al. · 2026 · Pharmacological research
Gut-liver axis disturbance is the unifying pathogenesis of cholestatic liver diseases. The purpose of this study was to explore the underlying mechanisms of the probiotic Lactobacillus amylovorus (LA) and its secreted extracellular…
View details →DOI: 10.1016/j.phrs.2026.108152 Negative / Null Result Report
Sohal P, Gupta K, Kaushal S et al. · 2025 · Preprint
ABSTRACT Objective Acute isoniazid toxicity causes refractory seizures due to pyridoxine deficiency-mediated gamma-aminobutyric acid depletion. While pyridoxine is the established antidote, its limited availability in emergency settings…
View details →DOI: 10.1101/2025.09.17.676905 Negative / Null Result Report
Huchthausen C, Shi M, Sousa GL et al. · 2025 · Preprint
Abstract Radiomics-based machine learning models have the potential to detect lung cancer at inception from CT scans and transform patient outcomes. Low malignancy rates in early-development pulmonary nodules (PNs) and variable image…
View details →DOI: 10.21203/rs.3.rs-7350820/v1 Negative / Null Result ReportMedicine
Timimi S · 2025 · Child and adolescent mental health
Because definitions of mental disorder are inescapably subjective, they can be continuously expanded in response to commercial, guild and social interests and pressures. In this article, I argue that this has resulted in young people…
View details →DOI: 10.1111/camh.70015 Negative / Null Result Report
Moncheaux A, Guimond A, Spiegelhalter C et al. · 2025 · Preprint
ABSTRACT Background Mutations in CAV3 , encoding caveolin-3, cause caveolinopathies, rare genetic disorders affecting both skeletal and cardiac muscle. Caveolin-3 contributes to T-tubule formation and excitation-contraction coupling. BIN1…
View details →DOI: 10.1101/2025.09.26.678914 Negative / Null Result ReportOpen accessMedicine
Fujii T, Nogami Y, Seo T · 2026 · BMJ open
Objectives Cognitive behavioural therapy (CBT) is recommended as a first-line treatment for depression and anxiety disorders, but its utilisation under Japan's national health insurance remains poorly understood. This study aimed to…
View details →DOI: 10.1136/bmjopen-2025-115722 Negative / Null Result ReportMedicine
Ead AS, Wirkus J, Machuca J et al. · 2026 · The Journal of nutrition
Background Pancreatic ductal adenocarcinoma is a deadly cancer linked to obesity. Adipose tissue contributes to tumor progression by promoting inflammation and supplying lipids and cytokines that support cancer growth. Although omega-6…
View details →DOI: 10.1016/j.tjnut.2025.101286 Negative / Null Result ReportOpen accessMedicine
Mudupula Vemula SS, Adhikari S, Motkur S et al. · 2026 · Cureus
Thrombotic thrombocytopenic purpura (TTP) is a rare, life-threatening thrombotic microangiopathy (TMA) characterized by microangiopathic hemolytic anemia, thrombocytopenia, and end-organ dysfunction, with high untreated mortality that can…
View details →DOI: 10.7759/cureus.110006 Negative / Null Result ReportMedicine
Alpat SE, Kaya B, Nakkaş HG et al. · 2026 · Burns : journal of the International Society for Burn Injuries
Objective Despite notable advancements in burn care, morbidity and mortality remain high, with progressive tissue loss typically occurring in the first 48 h post-injury. While microneedling and topical retinyl palmitate are recognized for…
View details →DOI: 10.1016/j.burns.2025.107811 Negative / Null Result ReportOpen accessComputer Science
A. Hietanen, K. Kajantie, M. Laine et al. · 2008 · arXiv
We update Monte Carlo simulations of the three-dimensional SU(3) + adjoint Higgs theory, by extrapolating carefully to the infinite volume and continuum limits, in order to estimate the contribution of the infrared modes to the pressure of hot QCD. The sum of infrared contributions beyond the known 4-loop order turns out to be a smooth function, of a reasonable magnitude and specific sign. Unfortunately, adding this function to the known 4-loop terms does not improve the match to four-dimensional lattice data, in spite of the fact that other quantities, such as correlation lengths, spatial str
Negative / Null Result ReportOpen accessPhysics
Yunxiao Zhang, Nan Huo, Liang Cui et al. · 2022 · arXiv
In classical coherence theory, coherence time is typically related to the bandwidth of the optical field. Narrowing the bandwidth will result in the lengthening of the coherence time. This will erase temporal distinguishability of photons due to time delay in pulsed photon interference. However, this is changed in an SU(1,1)-type quantum interferometer where quantum entanglement is involved. In this paper, we investigate how the temporal coherence of the fields in a pulse-pumped SU(1,1) interferometer changes with the bandwidth of optical filtering. We find that, because of the quantum entangl
Negative / Null Result ReportOpen accessComputer Science
Lei Wang, Ee-Peng Lim · 2024 · arXiv
Large language models (LLMs) have shown excellent performance on various NLP tasks. To use LLMs as strong sequential recommenders, we explore the in-context learning approach to sequential recommendation. We investigate the effects of instruction format, task consistency, demonstration selection, and number of demonstrations. As increasing the number of demonstrations in ICL does not improve accuracy despite using a long prompt, we propose a novel method called LLMSRec-Syn that incorporates multiple demonstration users into one aggregated demonstration. Our experiments on three recommendation
Negative / Null Result ReportOpen accessComputer Science
Maximilian Spliethöver, Jonas Klaff, Hendrik Heuer · 2019 · arXiv
Attention mechanisms have seen some success for natural language processing downstream tasks in recent years and generated new State-of-the-Art results. A thorough evaluation of the attention mechanism for the task of Argumentation Mining is missing, though. With this paper, we report a comparative evaluation of attention layers in combination with a bidirectional long short-term memory network, which is the current state-of-the-art approach to the unit segmentation task. We also compare sentence-level contextualized word embeddings to pre-generated ones. Our findings suggest that for this tas
