Negative / Null Result ReportOpen accessMedicine
Yoonhee Shin, Bohyun Park, Nam-eun Kim et al. · 2022 · Journal of Preventive Medicine and Public Health
Objectives The aim of this study was to evaluate the subjective level of health-related quality of life of Korean healthcare workers using various quality-of-life instruments. Methods This study included 992 participants, who were doctors and nurses. A survey was conducted between November 28 and December 4, 2019. Data from 954 participants divided into 3 groups (physicians, residents, and nurses) were analyzed. Four measurement tools (29 questions) were used in the survey to evaluate subjective health status and well-being. Results In the Mayo Well-being Index, burnout during work (88.5%) and
View details →DOI: 10.3961/jpmph.22.114 Negative / Null Result ReportOpen accessDiseases of the musculoskeletal system
Yan-Tao Ma, Yu-Lin Dong, Bo Wang et al. · 2023 · BMC Musculoskeletal Disorders
Abstract Background Latent and active myofascial trigger points (MTrPs) in knee-associated muscles may play a key role in pain management among patients with knee osteoarthritis (KOA). The aim of this study was to investigate the effect of dry needling treatment on pain intensity, disability, and range of motion (ROM) in patients with KOA. Methods This randomized, single-blinded, clinical trial was carried out for 6 weeks of treatment and 6-month follow-up. A total of 98 patients met the entry criteria and were randomly assigned to the dry needling latent and active myofascial trigger point (M
View details →DOI: 10.1186/s12891-022-06116-9 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Juan Duchesne, David McGreevy, Kristofer Nilsson et al. · 2020 · Journal of Endovascular Resuscitation and Trauma Management
Background: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is becoming a standardized adjunct in the management of non-compressible hemorrhage. Ultrasound (US)-guided femoral access has been taught as the best practice for femoral artery cannulation. However, there is a lack of evidence to support its use in patients in extremis with severe hemorrhage. We hypothesize that no differences in outcome will exist between US-guided and to blind percutaneous or cutdown access methods. Methods: This was an international, multicenter retrospective review of all patients managed with
View details →DOI: 10.26676/jevtm.v4i2.139 Negative / Null Result ReportOpen accessOcean engineering
Jiaxing Xin, Ying Cui, Jun Yang et al. · 2025 · IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
The intensification of the urban heat island (UHI) effect poses a serious threat to public health, particularly in cities. Effectively mitigating UHI has been a focus of national and international academic research over the last decades. However, most contemporary research has focused on land use mitigation measures within urban areas, with less emphasis on suburban land use. To address this research gap and explore spatial characteristics, we analyzed the driving mechanism of suburban land use patterns on UHI intensity (UHII) within the main urban area of Shenyang City based on high spatial r
View details →DOI: 10.1109/jstars.2025.3587268 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Bilan Yang, Xiaoli Xi, Hongsheng Yu et al. · 2024 · Cancer Reports
Abstract Background The optimal treatment strategy for early‐stage hepatocellular carcinoma (HCC) remains controversial, specifically in regard to surgical resection (SR) and ablation. The aim of this study was to investigate the impact of SR and ablation on recurrence and prognosis in early‐stage HCC patients, to optimize treatment strategies and improve long‐term survival. Methods A retrospective analysis was conducted on 801 patients diagnosed with Barcelona Clinic Liver Cancer (BCLC) stage 0/A HCC and treated with SR or ablation between January 2015 and December 2019. The effectiveness and
View details →DOI: 10.1002/cnr2.2030 Negative / Null Result ReportOpen accessMedicine
Wade J. Chalker, Anthony J. Shield, David A. Opar et al. · 2018 · PeerJ
Background Hamstring strain injuries (HSI) are one of the most prevalent and serious injuries affecting athletes, particularly those in team ball sports or track and field. Recent evidence demonstrates that eccentric knee flexor weakness and between limb asymmetries are possible risk factors for HSIs. While eccentric hamstring resistance training, e.g. the Nordic hamstring exercise (NHE) significantly increases eccentric hamstring strength and reduces HSI risk, little research has examined whether between limb asymmetries can be reduced with training. As augmented feedback (AF) can produce sig
View details →DOI: 10.7717/peerj.4972 Negative / Null Result ReportOpen accessMedicine (General)
Wei-Kai Chuang, Skye Hung-Chun Cheng, Chen-Fang Hung et al. · 2022 · Journal of the Formosan Medical Association
Background/purpose: This study aimed to analyze the long-term outcomes of hypofractionated whole-breast irradiation (WBI) (HF-WBI) compared with those of conventionally fractionated WBI (CF-WBI) for early breast cancer treated with breast-conservation surgery (BCS) and adjuvant WBI in Taiwan. Methods: This study included patients treated at our institution between 2012 and 2016. All patients with early breast cancer received BCS (pT1–2, pN0, M0) and adjuvant WBI through one of two treatment schemes. Propensity score matching analysis was conducted to create comparable cohorts. The major result
View details →DOI: 10.1016/j.jfma.2022.01.015 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
Hao WANG, Zhitao GU, Jianyong DING et al. · 2016 · Chinese Journal of Lung Cancer
Background and objective Video-assisted thoracoscopic surgery (VATS) theoretically offers advantages over open thymectomy for clinically early-stage (Masaoka-Koga stage I and II) thymic malignancies. However, longterm outcomes have not been well studied. We compared the postoperative outcomes and survival from a cohort study based on the database of the Chinese Alliance for Research in Thymomas (ChART). Methods Between 1994 and 2012, data of 1,117 patients having surgery for clinically early-stage (Masaoka-Koga stage I and II) tumors were enrolled for the study. Among them, 241 cases underwent
View details →DOI: 10.3779/j.issn.1009-3419.2016.07.07 Negative / Null Result ReportOpen accessMedicine
Flávio Kapczinski, Jair Mari, Luiz Henrique Junqueira Dieckmann et al. · 2024 · BMJ Open
Objective This study aims to conduct an overview on the comparative efficacy of valproate in acute mania, bipolar depression and maintenance treatment of bipolar disorder (BD).Method We performed an overview of systematic reviews with meta-analyses of randomised controlled trials (RCTs), registered in PROSPERO (CRD42024497749). We searched Medline and Cochrane Database of Systematic Reviews. Summary measures comparing valproate with placebo or other active drugs were described.Results We included 26 systematic reviews. For acute mania (31 RCTs, n=4376), valproate showed a significantly better
View details →DOI: 10.1136/bmjopen-2024-087999 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Zahra Ojaghi-Haghighi, Atoosa Mostafavi, Hassan Moladoust et al. · 2015 · Journal of Tehran University Heart Center
Background: Left ventricular (LV) twist is due to oppositely directed apical and basal rotation and has been proposed as a sensitive marker of LV function. We sought to assess the impact of chronic pure mitral regurgitation (MR) on the torsional mechanics of the left human ventricle using tissue Doppler imaging. Methods: Nineteen severe MR patients with a normal LV ejection fraction and 16 non-MR controls underwent conventional echocardiography and apical and basal short-axis color Doppler myocardial imaging (CDMI). LV rotation at the apical and basal short-axis levels was calculated from the
Negative / Null Result ReportOpen accessSurgery
Mohamed Nasr, Moustafa AH El-Nawasany, Haytham E Ali et al. · 2025 · JPRAS Open
Background: Diabetic foot ulcers (DFUs) are a serious complication of diabetes that can lead to significant morbidity. Autologous platelet-rich plasma (PRP), rich in growth factors and cytokines, has emerged as a promising treatment to enhance ulcer healing. This study aimed to compare the clinical and histological efficacy of injected PRP versus topically applied PRP and traditional wound care in the management of DFUs. Methods: Sixty patients with DFUs were randomly assigned to three equal groups (n = 20 each). Group A received locally injected autologous PRP; Group B received topically appl
View details →DOI: 10.1016/j.jpra.2025.08.008 Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Yongzhao Fan PhD, Linlin Zhang PhD, Xiaoyang Kong MD et al. · 2022 · American Journal of Alzheimer's Disease and Other Dementias
Background Previous studies have demonstrated that pre-exercise suppresses anxiety-like behavior, but the effects of different exercise times on vascular dementia induced anxiety-like behavior have not been well investigated. Objective The present study aims to investigate the underlying neurochemical mechanism of different pre-vascular-dementia exercise times on 5-HT and anxiety-like behavior in rats with vascular dementia. Methods 32 Sprague-Dawley (SD) rats were randomly divided into 4 groups: sham group (S group, n = 8), vascular dementia group (VD group, n = 8), 1-week physical exercise a
View details →DOI: 10.1177/15333175221082743 Negative / Null Result ReportOpen accessMedicine (General)
Hongseok Yoo, Jimi Oh, Chul Park · 2020 · Military Medical Research
Abstract Background In 2014, an outbreak of adenoviral pneumonia occurred in the Korean military training center. However, there are limited data on the characteristics of the fever and its response to antipyretic therapy in immunocompetent adults with adenovirus-positive community-acquired pneumonia (CAP). Methods The medical records of the patients who were admitted to the Armed Forces Chuncheon Hospital for the treatment of CAP between January 2014 and December 2016 were retrospectively analyzed. The patients were divided into three groups, namely, the adenovirus-positive (Adv) group, the a
View details →DOI: 10.1186/s40779-020-00235-x Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry
Tomoko Hyakumura, Tomoko Hyakumura, Ulises Aregueta-Robles et al. · 2021 · Frontiers in Neuroscience
Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement disorders such as those in people with Parkinson’s disease and more recently, in psychiatric conditions like obsessive compulsive disorder. Electrode-tissue interfaces that support safe and effective targeting of specific brain regions are critical to success of these devices. Development of directional electrodes that activate smaller volumes of brain tissue requires electrodes to operate safely with higher charge densities. Coatings such as conductive hydrogels (CHs)
View details →DOI: 10.3389/fnins.2021.761525 Negative / Null Result ReportOpen accessNeoplasms. Tumors. Oncology. Including cancer and carcinogens
C. Archili, P. Lissoni, G. Cattaneo et al. · 1990 · The International Journal of Biological Markers
The biological significance of soluble IL-2 receptors (sIL-2R) is still unknown; in particular, it is not yet clear whether their increase in the blood may reflect activation of immune cells, or whether it is related to an immune dysfunction. To investigate this problem, we evaluated serum levels of sIL-2R before and after administration of a highly lymphocytolitic chemotherapy (FEC: fluorouracil, epirubicin, cyclophosphamide) in a group of 6 patients with advanced breast cancer. SIL-2R were analyzed in relation to lymphocyte number. Absolute mean number of lymphocytes was significantly lower
View details →DOI: 10.1177/172460089000500109 Negative / Null Result ReportOpen accessMicrobiology
Philip El-Duah, Benjamin Meyer, Augustina Sylverken et al. · 2019 · Viruses
Known human coronaviruses are believed to have originated in animals and made use of intermediate hosts for transmission to humans. The intermediate hosts of most of the human coronaviruses are known, but not for HCoV-NL63. This study aims to assess the possible role of some major domestic livestock species as intermediate hosts of HCoV-NL63. We developed a testing algorithm for high throughput screening of livestock sera with ELISA and confirmation with recombinant immunofluorescence assay testing for antibodies against HCoV-NL63 in livestock. Optimization of the ELISA showed a capability of
View details →DOI: 10.3390/v11010043 Negative / Null Result ReportOpen accessAgriculture (General)
M. Behdarnejad, H. Piri, M. Delbari · 2023 · مجله آب و خاک
Introduction In sustainable farming systems, the use of organic fertilizers is of particular importance in increasing crop production and maintaining sustainable soil fertility. Nowadays, the consumption of organic foods is introduced to consumers as an alternative. The result of the application of chemical products is the crisis of environmental pollution, soil and water resources, and the health risk to human society. Nowadays, in order to reduce the effects of misuse of chemical inputs, chemical fertilizers can be replaced with organic biological fertilizers, including animal manure, compos
View details →DOI: 10.22067/jsw.2023.79296.1215 Negative / Null Result ReportOpen accessMedicine
Zhao Jiandong, Yuan Yongyi, Chen Jing et al. · 2012 · Journal of Translational Medicine
Abstract Background Many patients with enlarged vestibular aqueduct (EVA) have either only one allelic mutant of the SLC26A4 gene or lack any detectable mutation. In this study, multiplex ligation-dependent probe amplification (MLPA) was used to screen for copy number variations (CNVs) of SLC26A4 and to reveal the pathogenic mechanisms of non-syndromic EVA (NSEVA). Methods Between January 2003 and March 2010, 923 Chinese patients (481 males, 442 females) with NSEVA were recruited. Among these, 68 patients (7.4%) were found to carry only one mutant allele of SLC26A4 and 39 patients (4.2%) lacke
View details →DOI: 10.1186/1479-5876-10-82 Negative / Null Result ReportOpen accessDiseases of the circulatory (Cardiovascular) system
Takumi Osawa, Hitoshi Mori, Akane Kawai et al. · 2022 · Journal of Arrhythmia
Abstract Background Uninterrupted dabigatran during atrial fibrillation (AF) ablation is now established as the standard therapy. However, there are few reports on the effects of uninterrupted dabigatran on the intensity of anticoagulation during AF ablation. Methods We retrospectively analyzed 247 consecutive patients who underwent AF ablation in our hospital from January 2017 to December 2018. Patients who took warfarin or uninterrupted direct oral anticoagulants (DOACs) except for dabigatran were excluded. 89 patients underwent ablation with uninterrupted dabigatran (uninterrupted group, ma
View details →DOI: 10.1002/joa3.12655 Negative / Null Result ReportOpen accessDentistry
Hamed Kalhor, Mamak Adel, Maryam Tofangchiha et al. · 2026 · Annali di Stomatologia
Objectives: This study aimed to assess the effect of a metal artifact removal (MAR) algorithm on the visibility of the second mesiobuccal canal (MB2) of maxillary molars on cone-beam computed tomography (CBCT) scans. Materials and Methods: This cross-sectional study evaluated 41 CBCT scans of patients retrieved from the radiology clinic’s archives. The CBCT scans were saved with and without the MAR algorithm applied. The images were coded and evaluated by two endodontists to assess MB2 detection in maxillary molars and its visibility level using a 5-point Likert scale. Of the 164 samples, 32 w
View details →DOI: 10.59987/ads/2026.1.220-227 Negative / Null Result ReportOpen accessInternal medicine
LI Wen-hong, WANG Jin-wen, CHEN Hao et al. · 2015 · Linchuang shenzangbing zazhi
Objective To study the clinical curative effectiveness of high frequency ultrafiltration for the renal edema with diuretic resistance.Methods We selected 42 cases of nephrotic syndrome with severe edema.Among them,there were 20 cases of diabetic kidney disease,10 cases of lupus nephritis,8 cases of refractory primary nephrotic syndrome,and 4 cases of multiple myeloma nephropathy.All patients were subjected to standard treatment for 3-5 days according to different primary diseases after admission.Their urine was less than 800 mL every day and it met the standard of diuretic resistance.Then the
Negative / Null Result ReportOpen accessOphthalmology
Ritu Mali, Smruti R. Priyadarshini, Srikant K. Sahu et al. · 2024 · Indian Journal of Ophthalmology
Purpose: To compare the visual outcomes, postoperative complications, and graft asymmetry between precut and manually dissected donor tissues for Descemet stripping automated endothelial keratoplasty (DSAEK) and Descemet stripping endothelial keratoplasty (DSEK) procedures, respectively. Methods: Seventy eyes of 70 patients undergoing DSEK/DSAEK at a tertiary eyecare center in eastern India were included in this prospective randomized control study. The 70 eyes were divided equally into two groups. Group A (n = 35) and Group B (n = 35) underwent DSEK and DSAEK procedures, respectively. the ope
View details →DOI: 10.4103/ijo.ijo_3282_23 Negative / Null Result ReportOpen accessInfectious and parasitic diseases
Amira Al Balakosy, Mostafa Alfishawy, Omnia Elnabawy et al. · 2021 · Afro-Egyptian Journal of Infectious and Endemic Diseases
Background and study aim: Epidemiological data reported lower death rates of COVID-19 cases in countries with higher & recent coverage by measles containing vaccines. In this study we aim to identify measles IgG titer in COVID-19 patients & correlate it with disease severity. Patients and Method: This is a Cross-sectional study where 78 patients admitted to Ain Shams University Quarantine hospitals with positive PCR for SARS-CoV-2 were enrolled. All patients underwent quantification of serum measles IgG titer. Then classified according to the COVID-19 severity into mild, moderate and
View details →DOI: 10.21608/aeji.2021.72615.1144 Negative / Null Result ReportOpen accessMedicine
fatemeh marhemati, reza mir arab razi, mostafa azizi · 2020 · آموزش پزشکی
Background and Objective: Creating and developing self-directed learning skills has become one of the goals of education in recent decades, and today's students need to learn and acquire comprehensive information in this regard, or better to say, learn information and communication technology skills, to Be able to use electronic services. The purpose of this study was to investigate the relationship between electronic citizenship knowledge and self-directed learning of students of University of Mazandaran and Babol University of medical sciences. Methods: This study is descriptive-analytical i
Negative / Null Result ReportOpen accessPediatrics
Roberto Teggi, Bruno Colombo, Marco Familiari et al. · 2023 · Frontiers in Pediatrics
IntroductionVestibular impairment and vertigo in the pediatric population have an estimated prevalence ranging between 0.4% and 5.6% and are a topic of interest in recent years. The Bárány Society has recently reclassified migraine-related vertigo syndromes as vestibular migraine of childhood (VMC), probable vestibular migraine of childhood (probable VMC), and recurrent vertigo of childhood (RVC).MethodsApplying the criteria established by the Bárány Society, we retrospectively analyzed data on 95 pediatric patients suffering from episodic vertigo that were recruited from 2018 to 2022. In appl
View details →DOI: 10.3389/fped.2023.1152928 Negative / Null Result ReportOpen accessGynecology and obstetrics
Fedora Ambrosetti, MD, Giovanni Grandi, MD, Elisabetta Petrella, MD et al. · 2023 · AJOG Global Reports
BACKGROUND: The use of epidural analgesia represents the gold standard for pain management during labor, but the influence of the use of epidural analgesia on delivery mode is not fully understood. OBJECTIVE: This study aimed to analyze the impact of epidural analgesia on the delivery mode, namely, cesarean delivery, vaginal delivery, and operative vaginal delivery rates, in Robson class 1 women. STUDY DESIGN: A retrospective cohort study was conducted on all Robson class 1 women who delivered from January 1, 2019, to December 31, 2019, in the University Hospital of Modena. The primary outcome
View details →DOI: 10.1016/j.xagr.2023.100207 Negative / Null Result ReportOpen accessSports medicine
JL Ayers, M DeBeliso, TG Sevene et al. · 2016 · Biology of Sport
Olympic weightlifting movements and their variations are believed to be among the most effective ways to improve power, strength, and speed in athletes. This study investigated the effects of two Olympic weightlifting variations (hang cleans and hang snatches), on power (vertical jump height), strength (1RM back squat), and speed (40-yard sprint) in female collegiate athletes. 23 NCAA Division I female athletes were randomly assigned to either a hang clean group or hang snatch group. Athletes participated in two workout sessions a week for six weeks, performing either hang cleans or hang snatc
View details →DOI: 10.5604/20831862.1201814 Negative / Null Result ReportOpen accessPsychology
Arum Etikariena · 2019 · Jurnal Psikologi Undip
In recent years, research on innovation in organizations, particularly innovative work behaviors, has developed considerably. The objective of the study were to examine the role of individual characteristics such as age, gender, educational background, ethnic’s background, tenure and length in current position which presumably would have an impact on the formation of innovative work behaviors. The study is quantitative study with non-experimental design, conducted on 279 respondents working in a Syariah Bank and a television company. The measuring tool used is the Innovative Work Behavior Scal
View details →DOI: 10.14710/jp.17.2.107-118 Negative / Null Result ReportOpen accessPsychology
sara hasani, abolghasem mehrinezhad, Roshanak khodabakhsh pirkalani · 2020 · مجله علوم روانشناختی
Background: Obsessive-compulsive disorder is one of the most common and disabling psychological disorders. Many studies have investigated the effectiveness of mindfulness and exposure on the improvement of obsessive-compulsive disorder, but the key question is which of the two combinations of exposure, mindfulness, and mindfulness of exposure is most effective on obsessive-compulsive disorder in women? Aims: To compare the effects of exposure, mindfulness and mindfulness-exposure consciousness on combined obsessive-compulsive disorder in Arak women. Method: This was a quasi-experimental study
Negative / Null Result ReportOpen accessMedicine
LIU Yanan, WANG Likai, LIU Sisi et al. · 2019 · 口腔疾病防治
Objective To compare the polishing effects of three different polishing systems on machinable compos⁃ ite resins and to provide a basis for the rational selection of polishing systems in the clinic. Methods Block HC, Cerasmart, and Hyramic were fabricated into 90 test pieces. Then, 30 test pieces for each material were randomly divid⁃ ed into 3 groups with 10 pieces per group. The pieces were polished with the Vita Enamic® Polishing Set (Vita group), EVE RA341 composite polishing set (Eve group), and Toboo M elastic ceramic polishing set (Tob group). The surface roughness and gloss of each tes
View details →DOI: 10.12016/j.issn.2096⁃1456.2019.07.006 