e-ISSN: Pending
Negative / Null Result ReportOpen accessNeurosciences. Biological psychiatry. Neuropsychiatry

Different Exercise Time on 5-HT and Anxiety-like Behavior in the Rat With Vascular Dementia

Yongzhao Fan PhD; Linlin Zhang PhD; Xiaoyang Kong MD; Kun Liu PhD; Hao Wu PhD · 2022 · American Journal of Alzheimer's Disease and Other Dementias

WASTE classifies this as Negative / Null Result Report · AI classification, approximate

The study found no significant effect — useful as a negative control or null benchmark for your own design.

Abstract

Background Previous studies have demonstrated that pre-exercise suppresses anxiety-like behavior, but the effects of different exercise times on vascular dementia induced anxiety-like behavior have not been well investigated. Objective The present study aims to investigate the underlying neurochemical mechanism of different pre-vascular-dementia exercise times on 5-HT and anxiety-like behavior in rats with vascular dementia. Methods 32 Sprague-Dawley (SD) rats were randomly divided into 4 groups: sham group (S group, n = 8), vascular dementia group (VD group, n = 8), 1-week physical exercise a

Abstract by Yongzhao Fan PhD; Linlin Zhang PhD; Xiaoyang Kong MD; Kun Liu PhD; Hao Wu PhD, American Journal of Alzheimer's Disease and Other Dementias (2022) — licensed CC BY 4.0.

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Metadata source: DOAJ · DOI 10.1177/15333175221082743