Improving Deep Brain Stimulation Electrode Performance in vivo Through Use of Conductive Hydrogel Coatings
Tomoko Hyakumura; Tomoko Hyakumura; Ulises Aregueta-Robles; Wenlu Duan; Joel Villalobos; Joel Villalobos; Wendy K. Adams; Laura Poole-Warren · 2021 · Frontiers in Neuroscience
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract
Active implantable neurological devices like deep brain stimulators have been used over the past few decades to treat movement disorders such as those in people with Parkinson’s disease and more recently, in psychiatric conditions like obsessive compulsive disorder. Electrode-tissue interfaces that support safe and effective targeting of specific brain regions are critical to success of these devices. Development of directional electrodes that activate smaller volumes of brain tissue requires electrodes to operate safely with higher charge densities. Coatings such as conductive hydrogels (CHs)
Abstract by Tomoko Hyakumura; Tomoko Hyakumura; Ulises Aregueta-Robles; Wenlu Duan; Joel Villalobos; Joel Villalobos; Wendy K. Adams; Laura Poole-Warren, Frontiers in Neuroscience (2021) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Chronic stress induces insulin resistance and enhances cognitive impairment in AD
Negative / Null Result ReportSimilarities (and Differences) in the Learning Patterns of Single-Word Reading of an Alphabetic Orthography in Monolingual and Bilingual Primary School Children: A Cross-Sectional Study
Negative / Null Result ReportThe Impact of Acute Aerobic Exercise on General and Food-Related Inhibitory Function Among Young Adults with Obesity: An Event-Related Potential (ERP) Study
Negative / Null Result ReportEffects of simvastatin on white matter integrity in healthy middle‐aged adults
Negative / Null Result ReportRepetitive temporal interference stimulation improves jump performance but not the postural stability in young healthy males: a randomized controlled trial
Negative / Null Result ReportImpact of Rural vs. Urban Residence on Survival Rates of Patients with Glioblastoma: A Tertiary Care Center Experience
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.3389/fnins.2021.761525
