A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19850 results in Negative / Null Result Report · page 336 of 662
Wu YH, Chang CF, Chien WH · 2026 · Journal of clinical medicine
Background/Objectives : Approximately 17 million individuals worldwide experience stroke annually. Stroke-induced cerebral hypoxia or infarction can impair multiple cognitive domains. This study aims to monitor the cognitive abilities of…
Labronici PJ, de Campos JP, de Araújo Almeida JP et al. · 2026 · European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
OBJECTIVES: To evaluate, using ultrasonography and the AOFAS (The American Orthopaedic Foot and Ankle Society) score, changes in the peroneal tendons of patients with ankle fractures resulting from a supination-external rotation (SER)…
Ruffin C, Schmiedt C, Dantino S et al. · 2026 · Journal of feline medicine and surgery
ObjectivesCats undergoing perineal urethrostomy (PU) often have acute kidney injury (AKI). Minimizing additional kidney injury during anesthesia is critical to prevent exacerbation of AKI. The impact of surgical positioning for PU on…
Hoon OH, Leung SY, Ko TY et al. · 2026 · Cureus
Background and purpose Contrast-enhanced mammography (CEM) has emerged as a valuable imaging modality for breast cancer detection and management. Background parenchymal enhancement (BPE) reflects the level of normal glandular tissue…
Toavs TL, Sudheendra VH, Barrett T et al. · 2026 · The Journal of arthroplasty
Background Cryoanalgesia is increasingly used in total knee arthroplasty (TKA) as a nonopioid pain control modality. This study evaluated the effect of cryoanalgesia on postoperative opioid use and recovery of range of motion in patients…
Rosenthal S, Megla E, Bainbridge W · 2026 · Preprint
It is well known that memory fades over time, but it is unclear how actions taken between encoding and recall affect this fading, especially for visual recall. To assess the effect of sleep on visual recall, we conducted two experiments.…
Brodkorb T, Elnahrawy A, Spaich S et al. · 2026 · Archives of gynecology and obstetrics
Purpose The aim of this study was to evaluate sexual function in the long term after total laparoscopic hysterectomy (TLH) versus laparoscopic supracervical hysterectomy (LASH) in patients with benign indications. Methods As part of a…
Jamali A, Hamishehkar H, Memar MY et al. · 2026 · Clinical and experimental dental research
Objectives Hypericum perforatum L. offers several beneficial effects, for example antioxidant, antitumor, wound healing. Our aim was to ascertain the effect of H. perforatum extract gum on salivary Streptococcus mutans count, pH, plaque…
Ramadhan D, Al-Rasheedy M, Alsarraj L · 2026 · Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina
Objective For evaluation of predictive factors of sponataneous conception after saline infused sonosalpingography (SIS). Method A prospective study was conducted from August 2023 to December 2024 at reproductive medial unit at…
Salcedo GG, Galvis JSS, Medina SEM et al. · 2026 · Neurourology and urodynamics
Introduction The intravesical injection of onoabotulinum toxin A is a cornerstone in the management of overactive bladder. Traditionally, treatment involves 20 injection sites, avoiding the bladder trigone. Recent studies have shown that…
Masumi Z, Bagheri M, Feizi R et al. · 2026 · BMC nursing
Background The rising use of C-arm fluoroscopy in operating rooms raises occupational safety concerns for perioperative nurses. They may face scattered ionizing radiation despite not being classified as radiation workers. This study…
Bolgen C, Karluka I · 2026 · Annals of vascular surgery
Background The study examines whether omitting local anesthesia at the tunneling site during subcutaneous port catheter implantation is associated with differences in patient comfort and procedural outcomes through pain assessment during…
Baybora H, Özal E, Özal SA · 2026 · BMC ophthalmology
Background There are research findings suggesting that antiglaucoma agents may reduce aqueous humor outflow and decrease the elimination of intravitreally administered anti-vascular endothelial growth factor agents, prolonging their…
Ahiati JM · 2026 · Preprint
This research study examined the level of stress and depression associated with students and how social support influences the stress and depression levels of students. There are several interactions between stress, depression, and social…
Imai K, Abe J, Chikazawa K et al. · 2026 · Journal of clinical medicine
Background/Objectives : Vaginal natural orifice transluminal endoscopic surgery (vNOTES) is increasingly being used to avoid abdominal incisions; however, its mid-term oncological safety in endometrial cancer remains unclear. Methods :…
Sharma K, Israilevich RN, Ross E et al. · 2026 · Retina (Philadelphia, Pa.)
Purpose The study compares refractive outcomes of secondary intraocular lens (SIOL) surgery performed by vitreoretinal, anterior segment, and both surgeons. Methods Eyes included in this study underwent SIOLfrom 2012-2024and had a final…
ALqaraghuli MiA, Sheadeed Nm, karim AK et al. · 2026 · Preprint
Abstract Background: As multiple sclerosis (MS) is a long-lasting and highly variable disease, treatment aims to focus on reducing relapses and preventing the buildup of disability over time. Choosing an effective first disease-modifying…
Laughlin M, Jack JT, Stephens SE et al. · 2026 · PloS one
Intracardiac flow analysis aims to evaluate blood flow patterns and associated parameters for the assessment of cardiac function. However, there is limited understanding as to how flow parameters are influenced by various sources, such as…
Qin D, Nan Y, Zhu H et al. · 2026 · Frontiers in medicine
Aim To develop a reusable prototype electric silicone oil injector and aspirator and to compare its performance with that of a vitrectomy machine-based system and a manual syringe technique in an ex vivo porcine eye model. Methods The…
Li H, Li T, Guo Y et al. · 2026 · Frontiers in medicine
Background To evaluate the clinical efficacy of ciprofol versus propofol combined with alfentanil for anesthesia in patients undergoing hysteroscopic transcervical resection of submucosal myomas. Methods A total of 208 patients scheduled…
Thanawala S, Shah R, Alluri KV et al. · 2026 · Medicine
Background The adaptogenic effects of Ashwagandha root extract are evident. An earlier study showed the therapeutic effects of a once-daily sustained-release (SR) formulation (300 mg) of Ashwagandha root extract over an extended period.…
Kafle A, Singh S, Singh M et al. · 2026 · Frontiers in plant science
Understanding crop root growth and distribution and soil water depletion under water deficit conditions is critical for developing sustainable production practices for cucumber ( Cucumis sativus L.) in semi-arid regions like West Texas.…
Tripathi R, Dahal S, Acharya N et al. · 2026 · Journal of Nepal Health Research Council
Background Postoperative pain is a most common symptom of endodontic patients after root canal treatments (RCTs). The aim of this study was to evaluate Postoperative pain during and after root canal treatment (RCT) among patients at a…
Sarkis H, Kerhani AA, Hedderich DM et al. · 2026 · World neurosurgery
Background/objective Shunt-dependent hydrocephalus represents a major complication of aneurysmal subarachnoid hemorrhage (aSAH), yet no universally adopted CT-based prediction tool exists. Fisher-based scales suffer from a ceiling effect…
Devletli Ozygit L, Eyuboglu GB · 2026 · American journal of dentistry
Purpose To investigate comparatively the changes in surface roughness and surface microhardness of resin composites applied with traditional incremental layering technique and bulk-fill resin composites after erosive/abrasive applications.…
Zhang X, Li Y, Fang Y et al. · 2026 · Frontiers in bioengineering and biotechnology
Objective Based on the existing research that predominantly focuses on loaded level walking or employs discrete-point methods to analyze stair negotiation, this study utilizes functional data analysis to systematically investigate the…
Bayrakçi O · 2026 · Medicine
Surgical treatments of the thorax are one of the most painful surgeries known. Postoperative pain is an important factor affecting treatment success, hospital stay, complications, duration of chest tube placement, and respiratory dynamics.…
Zeilinger J, Regitnig P, Kronschläger M et al. · 2026 · Journal of cataract and refractive surgery
Purpose To compare decentration, tilt, and dynamic stability ("wobble") between retropupillary fixated iris claw intraocular lenses (IOL) and double needle flanged scleral fixated technique. Setting Vienna Institute for Research in Ocular…
Ding X, Yan L, Yang Q et al. · 2026 · Preprint
Abstract BACKGROUND Septic shock, prevalent in critical care medicine, poses significant treatment challenges and high mortality rates. Its pathogenesis involves an inflammatory cytokine storm and microcirculatory dysfunction, potentially…
Gund MP, Naim J, Wittig J et al. · 2026 · BMC oral health
Background Chlorhexidine (CHX) can lower the bacterial contamination on masks. This study explores how effectively CHX reduces the bacterial spectrum in the patient's oral cavity and subsequently how this influences the contamination of…