BmK IT2 suppresses proliferation while differentially modulates migration and invasion of neural tumor cells: Association with down-regulation of functional VGSCs and transcriptional reprogramming.
Jing S; Wang J; Cheng S; Ma Q; Tao J; Wang H; Ji Y; Tan Z · 2026 · Toxicon : official journal of the International Society on Toxinology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
Abstract (excerpt)
Voltage-gated sodium channels (VGSCs) are emerging therapeutic targets for cancers including neural tumors such as neuroblastomas and gliomas. BmK IT2, a neurotoxic polypeptide from the scorpion Buthus martensii Karsch, is a known…
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Metadata source: Europe PMC · DOI 10.1016/j.toxicon.2026.109166