A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
19850 results in Negative / Null Result Report · page 335 of 662
Akitomo T, Kaneki A, Nishimura T et al. · 2026 · International dental journal
Although many studies have examined large language models (LLMs) for dental diagnosis, most focus on a single topic, and few have investigated their broader usefulness for the variety of patients. Twenty-five cases meeting the eligibility…
Zeynali N, Akbari M, Ghezelbash S · 2026 · Journal of education and health promotion
Background Since chronic heart failure would cause various physical outcomes and limitations, it could create significant changes in the mental status of the patients. One of the problems among these patients is increased stress levels.…
Akarakian R, Geamanu A, Moffat A et al. · 2026 · BMC musculoskeletal disorders
BACKGROUND: Jumper’s knee or patellar tendinosis is a debilitating condition occurring in up to 40% of athletes that perform jumping, rapid acceleration and deceleration movements. Minimally invasive percutaneous ultrasonic tenotomy…
Eşkil KG, Eşkil R, Yapıcı A · 2026 · BMC sports science, medicine & rehabilitation
Background The present study aims to examine the impact of badminton training programs on the attention and motor skills performance of students with specific learning disabilities (SLDs). Methods The study was carried out with students at…
Shin C, Riehl JT · 2026 · The journal of knee surgery
Abstract As the population continues to grow and age, the number of projected total knee arthroplasty (TKA) procedures is expected to grow substantially by 2030. This retrospective study reviews peripheral vascular disease (PVD) and…
Saleh RS, Elbattawy EA, Hamza S et al. · 2026 · Scientific reports
The aim of this study was to compare the effect of Calcium Aluminate- Calcium Silicate based experimental pulp capping material with the commercially available Mineral Trioxide Aggregate (MTA) in terms of dentin bridge formation and pulp…
Kataruka M, Sk J, Bhattacharjee S et al. · 2026 · Cureus
Background Orthotic intervention is a non-invasive and commonly used treatment for trigger finger (TF). Among the various splinting options, the comparative effectiveness of proximal interphalangeal joint block orthosis (PIPJ-BO) and…
Jang M, Kwon S · 2026 · Preprint
Abstract Background The WTO TRIPS flexibilities serve as a health safeguard that protects access to medicines (ATM) by allowing flexibility in pharmaceutical patents. Engaging with state and capital powers, civil society organizations…
Aziz NN, Hassan RM, Ibrahim RA et al. · 2026 · Clinical medicine insights. Arthritis and musculoskeletal disorders
Background Late-onset rheumatoid arthritis (LORA) poses a great challenge for physicians regarding diagnosis and treatment. The prognosis for LORA was better in some early research but worse in more recent trials. Objectives The study aim…
Liu B, Li J, Dai S et al. · 2026 · The Journal of craniofacial surgery
To investigate the difference between the 3-dimensional structure of the cavity in patients with isolated cleft palate and Pierre-Robin syndrome with cleft palate. Retrospective measurements of high need ratio (NR), velopharyngeal gap…
Guo L, Wang J, Du D · 2026 · Frontiers in oncology
Purpose To investigate the efficacy and safety of deep hyperthermia combined with tislelizumab and chemotherapy in patients with advanced squamous non-small cell lung cancer (NSCLC). Methods A total of 100 patients with advanced squamous…
Domingo PT, Berger GK, Gray P et al. · 2026 · The Journal of the American Academy of Orthopaedic Surgeons
Purpose We evaluated the safety outcomes of opioids alone versus opioids plus low-dose gabapentinoids in patients naïve to both opioids and gabapentinoids, after total joint arthroplasty (TJA) of the knee, hip, or shoulder. Methods This…
Lin Z, Chen Y, Zang H et al. · 2026 · Operative neurosurgery (Hagerstown, Md.)
Background and objectives Bone and soft tissue tumors are significant causes of limb amputation. Regenerative peripheral nerve interface (RPNI) is an effective method for preventing neuroma formation in residual nerves. However, the…
Monteiro L, Lima J, Silva L et al. · 2026 · Journal of clinical medicine
Background: Artificial intelligence (AI) is expected to play an increasingly important role in medicine and dentistry. While its diagnostic potential has been tested in various medical fields, limited research exists on its applications…
Yoshikawa M, Yoshikawa Y, Uemura M et al. · 2026 · Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
This study investigated whether neuromuscular electrical stimulation (NMES) applied to the gluteus maximus alone or in combination with the hamstrings redistributes interface pressure in the sacral and ischial regions during 60°…
Abdullah NA, Hassan RK, Muhammed AK et al. · 2026 · Medicine
Ectopic pregnancy (EP) remains a major cause of early pregnancy-related morbidity and mortality. It can significantly impact future fertility and is associated with various risk factors. To investigate the incidence, clinical profile, and…
Adawy SNE, Aboulftouh DM, AbuAmu ST et al. · 2026 · The Saudi dental journal
To evaluate the stain resistance of repressed IPS Emax and Celtra Press after thermo-mechanical fatigue. Two pressable glass ceramics, IPS e.max press (Ivoclar, Vivadent) and Celtra press (Dentsply, Sirona), were used in this study. Thirty…
Almadani O, Alfakhri A, Asiri I et al. · 2026 · Pharmacoepidemiology and drug safety
Objective Incidents of infections associated with biosimilar biological disease-modifying antirheumatic drugs (bDMARDs) have been communicated to the Saudi Food and Drug Authority (SFDA). This study aimed to evaluate the infection risk…
Özfevzi R, Taner RL · 2026 · BMC oral health
Background Orthodontic malocclusion may affect both functional and psychosocial aspects of health; however, its relationship with global self-esteem in young adults remains unclear. This study aimed to compare self-esteem levels according…
Truong D, Nguyen KC, Chansangpetch S et al. · 2026 · Clinical ophthalmology (Auckland, N.Z.)
Purpose To compare the intraocular pressure (IOP)-lowering efficacy and safety of netarsudil, a Rho-associated kinase (ROCK) inhibitor, among eyes with open-angle glaucoma (OAG), combined-mechanism glaucoma (CMG), and angle-closure…
Wang R, Ren Y, Song Y et al. · 2026 · Journal of cardiothoracic surgery
Objective Comparison of the efficacy of the oXiris filter and the ST-100 filter in patients with postoperative cardiac surgery infections combined with acute kidney injury. Methods This is a retrospective cohort study of patients with…
Siddappa PK, Barakat MT, Zhou MJ et al. · 2026 · Surgical endoscopy
Background and aims Duodenoscopes with disposable distal end caps (DDEC) have been introduced to reduce the risk of transmitting multi-drug-resistant organisms compared to conventional reusable duodenoscopes (CRD). However, there have been…
Sharma I, Basu S, Nasir S et al. · 2026 · Ocular immunology and inflammation
Purpose Serpiginous-Like Choroiditis (SLC) is considered to be a subtype of tuberculosis associated uveitis and has been treated with either 6 or 9 months of Anti Tuberculosis therapy (ATT). However, ATT is associated with several adverse…
Okutucu M, Arpa M · 2026 · Preprint
Abstract Purpose This study aimed to evaluate vascular endothelial cell health through serum Syndecan-1 (SDC-1) level measurement in patients with diabetic retinopathy undergoing intravitreal anti-VEGF therapy and to increase the awareness…
Zhu Y, Zhang C, Yang H et al. · 2026 · BMC neurology
Background Clinical evidence of the potential treatment benefit of endovascular treatment (EVT) for M3 occlusion of the middle cerebral artery (MCA) is sparse. This study aims to compare EVT versus standard medical management (SMM) for…
Tora MS, Fofana F, Roach K et al. · 2026 · Journal of neurosurgery. Pediatrics
Objective In shunted pediatric hydrocephalus patients, the potential for shunt failure is a frequent cause of emergency department (ED) presentation. The assessment of papilledema through ophthalmological fundoscopic examination (OFE) is…
Jaramillo H, Slarve M, Long D et al. · 2026 · PloS one
Carbapenem-resistant Acinetobacter baumannii (CRAB), a Gram-negative bacterial pathogen, has been identified by Centers for Disease Control (CDC) as the top priority pathogen for which new antibiotics are needed. We found that the addition…
Letica L, Lubina IŠ, Brekalo Z et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : The incidence of colorectal cancer (CRC) in developed Western countries is constantly growing. CRC represents the third most common cancer and the second leading cancer-related cause of death worldwide. Innate…
Kang HI, Lee SJ, AlShomer F et al. · 2026 · Medicina (Kaunas, Lithuania)
Background and Objectives : Head and neck cancer (HNC) frequently necessitates reconstructive surgery due to defects following oncologic resection. The influence of age on reconstructive outcomes in head and neck cancer remains…
Jiang B, Wang S, Chu Y · 2026 · Preprint
Abstract Background Multiple Sclerosis (MS) is a chronic neurodegenerative disease, and social media platforms like TikTok and Bilibili play an increasingly important role in disseminating health information. However, the quality and…