Neoadjuvant docetaxel, oxaliplatin, and S-1 therapy for patients with large type 3 or type 4 gastric cancer: final outcomes of a multicenter, phase II study (OGSG 1902).
Endo S; Tanaka R; Yamaguchi T; Miyagaki H; Kawada J; Omori T; Takahashi N; Masuzawa T · 2026 · Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“The phase III JCOG0501 trial, which evaluated neoadjuvant S-1 plus cisplatin, failed to demonstrate any survival benefits.”
Abstract (excerpt)
Background Large type 3 (≥ 8 cm) and type 4 gastric cancers are associated with extremely poor prognoses. The phase III JCOG0501 trial, which evaluated neoadjuvant S-1 plus cisplatin, failed to demonstrate any survival benefits. Docetaxel,…
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Metadata source: Europe PMC · DOI 10.1007/s10120-025-01705-8