PET Study in a Patient with Spinocerebellar Degeneration before and after Long-Term Administration of Thyrotropin Releasing Hormone
H. Tanji; H. Nagasawa; T. Hayashi; H. Onodera; T. Fujiwara; M. Itoh; T. Ido; Y. Itoyama · 1996 · Behavioural Neurology
WASTE classifies this as Negative / Null Result Report · AI classification, approximate
The study found no significant effect — useful as a negative control or null benchmark for your own design.
The finding, in one line
“CMRG1c was markedly decreased in the cerebellum and there was no significant difference before and after the treatment, i.”
Abstract
We studied the chronic effect of thyrotropin releasing hormone (TRH) in a patient with spinocerebellar degeneration by measuring cerebral metabolic rate for glucose (CMRG1c) using 2-[18F]fluoro-2-deoxy-D-glucose (18FDG) and positron emission tomography (PET). A 56-year-old female, who had suffered from progressive ataxia for 2 years, was treated by intravenous administration of 2 mg TRH for 3 weeks, and CMRG1c of the brain was measured before and after treatment. CMRG1c was markedly decreased in the cerebellum and there was no significant difference before and after the treatment, i.e. mean CM
Abstract by H. Tanji; H. Nagasawa; T. Hayashi; H. Onodera; T. Fujiwara; M. Itoh; T. Ido; Y. Itoyama, Behavioural Neurology (1996) — licensed CC BY 4.0.
About to run something similar?
Run an AI Precheck on your own design to catch failure modes like this one before you spend the time. Your first desk check is free.
Related failures
Chronic stress induces insulin resistance and enhances cognitive impairment in AD
Negative / Null Result ReportSimilarities (and Differences) in the Learning Patterns of Single-Word Reading of an Alphabetic Orthography in Monolingual and Bilingual Primary School Children: A Cross-Sectional Study
Negative / Null Result ReportThe Impact of Acute Aerobic Exercise on General and Food-Related Inhibitory Function Among Young Adults with Obesity: An Event-Related Potential (ERP) Study
Negative / Null Result ReportEffects of simvastatin on white matter integrity in healthy middle‐aged adults
Negative / Null Result ReportRepetitive temporal interference stimulation improves jump performance but not the postural stability in young healthy males: a randomized controlled trial
Negative / Null Result ReportImpact of Rural vs. Urban Residence on Survival Rates of Patients with Glioblastoma: A Tertiary Care Center Experience
WASTE indexes this work — it does not host or republish it. Failure-type classification is automated and approximate.
Metadata source: DOAJ · DOI 10.3233/ben-1996-93-409