Negative / Null Result ReportMedicine
Tao Y, Zheng A, Li X et al. · 2026 · Surgical oncology
Objective To construct and validate a nomogram for predicting false-negative results of axillary lymph node (ALN) fine needle aspiration (FNA) in breast cancer (BC). Methods Using the surgical pathological results of axillary lymph nodes…
View details →DOI: 10.1016/j.suronc.2026.102425 Negative / Null Result ReportMedicine
Shukla A, Paturu T, Shivan S et al. · 2026 · Southern medical journal
Objective The objective of our study was to determine the extent of publication bias of clinical trials pertaining to the treatment of coronary artery disease. Specifically, studies are more likely to be published if the results are…
View details →DOI: 10.14423/smj.0000000000001955 Negative / Null Result ReportMedicine
Uchida S, Mizuguchi Y, Sato S et al. · 2026 · Journal of human genetics
Non-invasive prenatal testing (NIPT) is widely used for fetal aneuploidy screening; however, most evaluations of test accuracy rely on pregnancy outcomes rather than cytogenetic confirmation after birth, and evidence regarding the…
View details →DOI: 10.1038/s10038-026-01483-w Negative / Null Result Report
Sobhi A, Hegazy RM, Zolfakar DS et al. · 2026 · Preprint
Abstract Purpose Ovarian lesions are common diseases nowadays that should be diagnosed accurately. The Ovarian-Adnexal Reporting and Data System (O-RADS) classification helps to a great extent in categorizing the type of ovarian lesions,…
View details →DOI: 10.21203/rs.3.rs-8573044/v1 Negative / Null Result Report
Mayorga AP, Peña CO, Muñoz DB et al. · 2026 · Preprint
Abstract Background The rapid urease test (RUT) is widely used for Helicobacter pylori (H. pylori) diagnosis, but its diagnostic performance in advanced gastric atrophy remains poorly characterized. Aims To evaluate RUT accuracy against…
View details →DOI: 10.21203/rs.3.rs-9490483/v1 Negative / Null Result ReportMedicine
Abi Kheir DJ, Moriles K, Carr AL et al. · 2026 · The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians
Background: The (1,3)-β-D-glucan (BDG) test can be used as a stewardship approach to decrease antifungal overutilization, development of resistance, and excess costs. Objective: This study assessed the impact that a BDG algorithm has on…
View details →DOI: 10.1177/87551225261446911 Negative / Null Result ReportMedicine
Auer A, Settypalli TBK, Rozstalnyy A et al. · 2026 · BMC veterinary research
Background Rapid diagnosis is critical for the early detection and control of transboundary animal diseases such as African Swine Fever (ASF) and Avian Influenza (AI), particularly because it enables timely containment measures at the farm…
View details →DOI: 10.1186/s12917-026-05606-5 Negative / Null Result Report
Zougmore WAMJ, Kaboré NF, Bado P et al. · 2026 · Preprint
Abstract Background : Human Papillomavirus (HPV) testing is recommended as a high-performance screening method within the World Health Organization (WHO) global strategy for cervical cancer elimination. However, the programmatic…
View details →DOI: 10.21203/rs.3.rs-9484224/v1 Negative / Null Result ReportOpen accessMedicine
Saliba M, Haddad E · 2026 · International journal of surgery case reports
Introduction The most common type of vulvar cancer is squamous cell carcinoma. The management of early-stage vulvar squamous cell carcinoma includes radical local excision of the primary tumor. Evaluation of sentinel nodes for metastases…
View details →DOI: 10.1097/rc9.0000000000000450 Negative / Null Result ReportOpen accessMedicine
Lindsley IC, Juman MM, Seifert SN et al. · 2026 · PLoS neglected tropical diseases
Large host-virus association databases are increasingly used to explore broad questions in disease ecology, particularly around host range, pathogen diversity, and the potential for spillover. While these databases have been instrumental…
View details →DOI: 10.1371/journal.pntd.0013343 Negative / Null Result Report
Wright L, Hamze J, Nagrani TR et al. · 2026 · Preprint
Abstract Background Coronary artery disease (CAD) places a disproportionate burden on rural Appalachian communities. Scioto County, Ohio has among the highest rates of CAD-related hospitalizations in the state, approaching double the…
View details →DOI: 10.21203/rs.3.rs-9246863/v1 Negative / Null Result ReportMedicine
Ibrahim M, Mostafa D, Manie EA et al. · 2026 · British poultry science
1. This study used unvaccinated sentinels plus Avian Influenza Virus (AIV) specific ELISA for differentiating infected from vaccinated animals (DIVA). Birds assessed were from 10 broiler flocks (F1-F10), three layer (F11-F13) and two…
View details →DOI: 10.1080/00071668.2026.2645007 Negative / Null Result ReportOpen accessMedicine
Tavoly M, Jørgensen CT, Sandblad KG et al. · 2026 · Research and practice in thrombosis and haemostasis
Background It has been suggested that D-dimer testing should be avoided in patients with prolonged symptoms, as results may yield false negatives. However, the evidence supporting this recommendation is limited. Objectives This study…
View details →DOI: 10.1016/j.rpth.2026.103457 Negative / Null Result ReportOpen accessMedicine
Serrari M, Bianchi L, Tré-Hardy M et al. · 2026 · Microorganisms
Antenatal screening for Group B Streptococcus (GBS) does not always reflect intrapartum colonisation status, and rapid molecular point-of-care tests (POCT) have been developed to enable real-time detection during labour. This prospective…
View details →DOI: 10.3390/microorganisms14051060 Negative / Null Result ReportMedicine
McCulloch H, Lohr PA · 2026 · Obstetrics and gynecology
Objective To assess the accuracy of using the last menstrual period (LMP) date for determining gestational age, compared with ultrasonography, among patients aged younger than 16 years at British Pregnancy Advisory Service (BPAS), a large…
View details →DOI: 10.1097/aog.0000000000006242 Negative / Null Result Report
Özen A, Depoorter L, Huysentruyt K et al. · 2026 · Preprint
Background: /Objectives: Although cow’s milk allergy is the most common food allergy in infants, its diagnosis remains challenging. Conventional allergy tests, including skin prick testing and serum-specific IgE, can support the diagnosis…
View details →DOI: 10.20944/preprints202606.1225.v1 Negative / Null Result ReportMedicine
Yi J, Bi K, Shen M et al. · 2026 · Academic radiology
Objectives This study aimed to develop a post-procedural predictive model for assessing the risk of false-negative results in ultrasound-guided percutaneous transthoracic needle lung biopsy (US-PTLB). Material and methods Two prospective…
View details →DOI: 10.1016/j.acra.2025.10.023 Negative / Null Result ReportOpen accessMedicine
Ma JY, Jiang W, Cheng B et al. · 2026 · Endoscopic ultrasound
Background and objectives Repeated EUS-guided fine-needle aspiration/biopsy (rEUS-FNA/B) is recommended in solid pancreatic lesions (SPLs) with inconclusive initial results. However, even rEUS-FNA/B cannot completely eliminate false…
View details →DOI: 10.1097/eus.0000000000000171 Negative / Null Result ReportMedicine
Tsai CT, Liang SY, Lai CH et al. · 2026 · Infection
Purpose Non-induced sputum galactomannan (GM) testing is increasingly used in routine evaluation of suspected invasive pulmonary aspergillosis (IPA), yet its real-world performance and the clinical implications of negative results remain…
View details →DOI: 10.1007/s15010-026-02784-0 Negative / Null Result ReportMedicine
Anettová L, Jaume-Ramis S, Paredes-Esquivel C et al. · 2026 · Journal of helminthology
Pooling of gastropod samples is frequently used in surveys of the neurotropic nematode Angiostrongylus cantonensis to reduce cost and processing time. Here we highlight a potential limitation of this technique using the snail Theba pisana…
View details →DOI: 10.1017/s0022149x26101588 Negative / Null Result Report
Lienesch M, Sibbing U, Schürenkamp M et al. · 2026 · Preprint
Abstract Pre-ejaculate is a clear, sperm-free liquid secreted by the male bulbourethral glands. Pre-ejaculate is currently not a subject of routine forensic testing and consequently, often overlooked. The aim of this study was to…
View details →DOI: 10.21203/rs.3.rs-9823035/v1 Negative / Null Result Report
Majid GS, Abdulamir AS, Aufi IM · 2026 · Preprint
Background: The problem of transmissible human herpesvirus infections through blood donation has not been completely resolved by serological testing due to issues such as delayed in seroconversion or false-negative results. This study…
View details →DOI: 10.12688/f1000research.173833.2 Negative / Null Result ReportMedicine
Andronache J, Cichna-Markl M, Dobrovolny S et al. · 2026 · NPJ science of food
Food fraud through species substitution has been reported for edible gastropods, particularly in processed products where morphological identification is not feasible. DNA-based methods have been used to identify gastropod species in food…
View details →DOI: 10.1038/s41538-026-00961-x Failed Experiment ReportMedicine
Loeb SA, Tharp DL, Zawieja SD et al. · 2026 · Journal of cardiovascular pharmacology
Over 30 million individuals globally are afflicted with heart failure with preserved ejection fraction (HFpEF). Despite this substantial figure, treatment options for HFpEF remain limited. This is largely attributed to the variability in…
View details →DOI: 10.1097/fjc.0000000000001844 Negative / Null Result ReportOpen accessMedicine
Otwell T, Knight B, Coryell M et al. · 2025 · Frontiers in cellular and infection microbiology
Molecular diagnostic assays are critical tools to test, diagnose and treat infectious and other diseases. For example, PCR test results have been extremely valuable during the COVID-19 pandemic, not only to provide appropriate health care…
View details →DOI: 10.3389/fcimb.2025.1524025 Negative / Null Result ReportMedicine
Gudmundsdottir H, Hernandez-Delima FJ, McDowell BC et al. · 2026 · Surgery
Background Regional lymph node involvement impacts prognosis for patients with pancreatic neuroendocrine tumors and may influence management decisions for small tumors. Conventional cross-sectional imaging modalities have low sensitivity…
View details →DOI: 10.1016/j.surg.2026.110136 Negative / Null Result ReportOpen accessMedicine
Khoshakhlagh M, Dehghani T, Alizadeh A et al. · 2026 · Iranian journal of pathology
Background & objective Real-time PCR is widely used to detect SARS-CoV-2, the virus responsible for COVID-19, but false-negative results can occur even with internal controls. This study aimed to investigate the impact of using alternative…
View details →DOI: 10.30699/ijp.2025.2053609.3417 Negative / Null Result ReportOpen accessMedicine
Cañete FT, Williams L, Parry R et al. · 2026 · Forensic science international. Synergy
The Phadebas® Forensic Press Test (PFPT) is widely employed in forensic laboratories for presumptive saliva screening by observation of α-amylase activity. This enzyme hydrolyses starch embedded in the test paper, resulting in a blue…
View details →DOI: 10.1016/j.fsisyn.2026.100691 Negative / Null Result Report
Lesmanawati DAS, Widiasta A, Ghrahani R et al. · 2026 · Preprint
Abstract Background Patients with systemic lupus erythematosus (SLE) are at increased risk of tuberculosis (TB) because of disease-related immune dysregulation and prolonged immunosuppressive therapy. Screening for latent TB infection…
View details →DOI: 10.21203/rs.3.rs-9728431/v1 Negative / Null Result ReportMedicine
Liu M, Kong L, Sun W et al. · 2026 · Journal of immunotherapy (Hagerstown, Md. : 1997)
To investigate the clinical profile of nivolumab-induced autoimmune hemolytic anemia (AIHA) and to reveal the diagnostic and therapeutic patterns of this disease. Articles on nivolumab-induced AIHA published before October 31, 2025 were…
View details →DOI: 10.1097/cji.0000000000000612 