A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21290 results · page 322 of 710
Chen P, Zhao W, Li Y et al. · 2025 · BMC pregnancy and childbirth
OBJECTIVE: Thyroid hormones are essential for normal pregnancy and fetal development. The relationship between thyroid disease and the risk of spontaneous abortion (SA) and recurrent spontaneous abortion (RSA) has been reported, but…
Wengler K, Baker SC, Velikovskaya A et al. · 2024 · JAMA psychiatry
Importance The link between psychosis and dopaminergic dysfunction is established, but no generalizable biomarkers with clear potential for clinical adoption exist. Objective To replicate previous findings relating neuromelanin-sensitive…
Van J, Nielsen SE, Kirwan CB · 2022 · Preprint
Common research practices in neuroimaging studies using functional magnetic resonance imaging may produce outcomes that are difficult to replicate. Results that cannot be replicated have contributed to a replication crisis in psychology,…
Oberauer K · 2021 · Preprint
Some theorists argue that working memory is limited to a discrete number of items, and additional items are not encoded at all. Others assume that all items are represented with variable quality. Adam, Vogel, and Awh (2017) presented…
MAKINDE AI, Abiodun BJ, James R et al. · 2022 · Preprint
Abstract The West African westerly jet (WAWJ) plays a crucial role in Sahel precipitation, yet there is no information on how well climate models simulate the jet and its contribution to Sahel precipitation. This study examines the…
Kooij KL, Andreani NA, Keller L et al. · 2025 · The International journal of eating disorders
Objective Anorexia nervosa (AN) is a complex psychiatric disorder characterized by persistent dieting and reduced food intake, leading to significantly low body weight. Dysbiosis in the gut microbiome of patients with AN has been suggested…
Kotb A, Wagdy S, Sharaf H et al. · 2025 · Scientific reports
Preeclampsia is a multi-factorial disease, with both genetic and environmental factors contributing to its development. The genetic susceptibility in preeclampsia has been determined to be around 50%. STORKHEAD_BOX1 PROTEIN 1 (STOX1), is…
Long SK, Lee J, Yamani Y et al. · 2022 · Applied ergonomics
Trust is a critical factor that drives successful human-automation interaction in a myriad of modern professional environments. One seminal work on human-automation trust is Muir and Moray (1996) showing that human-machine trust evolves…
Stepanova EV, Strube MJ, Mazur KD · 2023 · The Journal of social psychology
In two studies, participants completed an implicit attractiveness task with faces as primes varying on (a) facial features from Afrocentric to Eurocentric and (b) skin tone from dark to light, and target pictures of environmental scenes…
Woestemeier A, Schwandt T, Lingohr P et al. · 2026 · Surgery open science
Introduction Abdominal surgery causes an inflammatory reaction in the intestines, resulting in a postoperative ileus. Mast cells can be divided into mucosal mast cells and connective tissue mast cells. In this study, we investigated mast…
Adjangba C, Border R, Romero Villela PN et al. · 2020 · Preprint
ABSTRACT Tobacco smoking is the leading cause of preventable death globally. Smoking quantity, measured in cigarettes per day (CPD), is influenced both by the age of onset of regular smoking (AOS) and by genetic factors, including a strong…
Jamil B, Su J, Elam K et al. · 2025 · Development and psychopathology
Introduction Past research suggests that polygenic scores for major depressive disorder (MDD-PGS), family conflict, and parental acceptance may all predict depressive outcomes among adolescents. Few studies have examined the interplay of…
Burris JL, Reider LB, Oleas DS et al. · 2024 · Acta psychologica
Researchers have proposed that humans have evolved psychological mechanisms that facilitate the detection, rapid response, and subsequent avoidance of potential threats. However, some inconsistent results in the literature have called into…
Chandrashekar SP, Adelina N, Zeng S et al. · 2022 · Preprint
People tend to stick with a default option instead of switching to another option. For instance, Johnson and Goldstein (2003) found a default effect in an organ donation scenario: if organ donation is the default option, people are more…
Chang WH, Hu TY, Kuo LK · 2026 · Diagnostics (Basel, Switzerland)
Background: Severe sepsis and septic shock remain major causes of ICU mortality despite advances in critical care. Polymyxin B hemoperfusion (PMX-HP) is widely used in Asia for refractory endotoxemia, yet the optimal session strategy…
Crawford J · 2020 · Preprint
Waytz, Dungan, and Young (2013) conducted four studies to test the hypothesis that valuing fairness over loyalty is more strongly associated with willingness to blow the whistle on transgressors than valuing loyalty over fairness. We…
Ma Y, Baker DJ, Vukovics K et al. · 2021 · Preprint
What factors affect listeners’ emotional perception of music? Ali and Peynircioğlu (2006) conducted a series of experiments on the listener's emotional response to melodies and lyrics in songs. Here we present a pre-registered replication…
Andrashko V, Novak T, Kopecek M et al. · 2026 · Therapeutic advances in psychopharmacology
Background Ketamine is a rapid-acting antidepressant with robust evidence, but unclear predictors of therapeutic response. Objectives Based on previous knowledge, hemodynamic parameters and acute altered state of consciousness have been…
Hong W, Yang Y, Xing Z · 2025 · BJPsych open
Background Depression in individuals with type 2 diabetes mellitus (T2DM) is associated with worse clinical prognosis; however, evidence regarding the relationship between depression and hypoglycaemic risk remains limited and inconclusive.…
Qi J, Yin Z, Peng Y et al. · 2025 · Journal of pharmaceutical policy and practice
Background Polymyxin B is increasingly used to treat infections caused by multidrug-resistant gram-negative bacteria; however, its widespread clinical use is hindered by the high incidence of nephrotoxicity. Antioxidants, such as vitamin…
Rotella A, Sparks AM, Mishra S et al. · 2021 · Preprint
Some evidence suggests that people behave more cooperatively and generously when observed or in the presence of images of eyes (termed the ‘watching eyes’ effect). Eye images are thought to trigger feelings of observation, which in turn…
Alton LA, Kutz T, Bywater CL et al. · 2024 · Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Metabolic cold adaptation, or Krogh's rule, is the controversial hypothesis that predicts a monotonically negative relationship between metabolic rate and environmental temperature for ectotherms living along thermal clines measured at a…
Asher MW, Hecht CA, Harackiewicz JM et al. · 2025 · Motivation science
According to expectancy-value theories of motivation, individuals choose to pursue tasks that they expect to succeed at and find personally valuable. Historically, researchers have often suggested that these two factors interact to…
Eshraghi N, Jayervand F, Hashemi N et al. · 2025 · BMC pregnancy and childbirth
Background To determine whether the combination of vaginal progesterone and cervical pessary initiated during the second trimester reduces the incidence of preterm birth and enhance neonatal outcomes among women diagnosed with singleton…
Sulfaro AA · 2026 · Psychonomic bulletin & review
Vividness judgements are intended to capture variance in the axis that uniquely separates the experience of a mental image from other unambiguously sensory perceptual experiences, and from a completely non-sensory experience of one's…
Petkova YP, Johnston JD, Collins AL · 2026 · Food science & nutrition
There is controversy regarding the differential metabolic effects of proteins from plant and animal sources. Existing literature focuses on a limited range of plant proteins consumed just before, or as part of, a mixed meal, resulting in…
Ventura GC, Ryan H, Yu HN et al. · 2026 · World journal of clinical pediatrics
Children born with fetal growth restriction (FGR) or small for gestational age (SGA) face an increased risk of motor and cognitive impairments, although prevalence and severity vary across studies due to differences in definitions,…
Rotondo F, Biddle K, Chen J et al. · 2022 · Neuroscience
The prospect of exploiting memory reconsolidation to treat mental health disorders has received great research interest, particularly following demonstrations that the β-adrenergic receptor antagonist propranolol, which is safe for use in…
Bakare AB, Lee Y, Hong J et al. · 2026 · Health care science
Background Assess ChatGPT and Bard's effectiveness in the initial identification of articles for Otolaryngology-Head and Neck Surgery systematic literature reviews. Methods Three PRISMA-based systematic reviews (Jabbour et al. 2017, Wong…
Zareba MR, Fafrowicz M, Marek T et al. · 2021 · Preprint
Abstract Humans can be classified as early, intermediate and late chronotypes based on the preferred sleep and wakefulness patterns. The anatomical basis of these distinctions remains largely unexplored. Using magnetic resonance imaging…