A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21710 results · page 321 of 724
SAW YH, CHAI HI, YAHYA NA et al. · 2026 · Preprint
Abstract Background Energy drinks are widely consumed acidic beverages that may compromise the longevity of resin composite restorations. However, limited evidence exists regarding the use of swept-source optical coherence tomography…
Pettenuzzo T, Sella N, Zarantonello F et al. · 2026 · Preprint
Abstract Background. High-flow nasal cannula (HFNC) is a promising respiratory support modality that improves oxygenation, alveolar recruitment, and comfort while reducing dead space compared to conventional oxygen therapy. Recently, a…
Dağlı E, Çapar ÖF, Sert S · 2026 · Scientific reports
This study examines the effects of freeze-thaw (F-T) cycles on the unconfined compressive strength (UCS) of untreated and stabilized soils using fly ash, lime, and lime-fly ash mixtures (30% FA, 5% L, and 30% FA + 5% L). Specimens were…
Ryou S, Jung Y, Kim DS et al. · 2026 · The Korean journal of internal medicine
Background/aims Few studies have compared modified endoscopic mucosal resection (EMR) techniques for small rectal neuroendocrine tumors (NETs). This study evaluated the clinical outcomes of ligation-assisted EMR (EMR-L) and precutting EMR…
Liu L, Shen Y, Yang S et al. · 2026 · Journal of biotechnology
As an enzyme cofactor, antioxidant, and stabilizer of cellular structures, Mn²⁺is essential for microbial growth, metabolism, and environmental adaptation. In this work, the impact of varying Mn²⁺ levels on caproic acid formation and…
Yilmaz AB, Karimzada K, Ozercan AY et al. · 2025 · Journal of robotic surgery
To evaluate the predictive value of the Estimation of Physiologic Ability and Surgical Stress (E-PASS) score, Comorbidity Score for Robotic Surgery (CRS) and Charlson Comorbidity Index (CCI) in relation to postoperative complications in…
Marshall MJ, Peck K, Hunter R et al. · 2024 · Behavioral sciences (Basel, Switzerland)
Eysenck's biopsychological model of stress posits that the extraversion-introversion distinction is associated with different thresholds of arousal, which in turn moderate the stress response. Although higher thresholds of activation have…
Gow J, Roofeh D · 2025 · Preprint
Abstract Background: Giant cell arteritis (GCA) is a large vessel vasculitis characterized by granulomatous inflammation classically affecting the carotid artery branches. GCA most often presents with one or more classic clinical features…
Graf J, Buder A · 2025 · Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
Primary erythrocytosis, also known as polycythemia vera, is a myoproliferative disease resulting in an increased red blood cell mass and is associated with increased hematocrit and hemoglobin concentrations. Patients have an augmented risk…
Khalifa H, Ayaty M, Oreaba R et al. · 2025 · Journal of the Egyptian National Cancer Institute
Objectives Following external beam radiation therapy (EBRT) with concurrent chemotherapy, we analyzed the benefits of surgical resection for locally advanced cervical carcinoma in terms of the frequency and severity of complications and…
Lyu HH, Wen X, Lin JT et al. · 2025 · Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
Objective: To compare the Kadish T staging, AJCC T staging, and Dulguerov T staging system in terms of their impact on surgical treatment selection and survival prognosis in patients with olfactory neuroblastoma (ONB). Methods: The cases…
Chen PY, Young TC, Lin CY et al. · 2025 · Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
Objective To determine the hearing outcomes in patients with sudden sensorineural hearing loss (SSNHL) after exposure to different brands of vaccines against COVID-19. Study design Cohort study. Setting Tertiary referral center. Patients…
Zheng X, Zhang T, Zhan T et al. · 2025 · Respiratory medicine
Purpose Positive end-expiratory pressure (PEEP) refers to a vital respiratory therapeutic tool for treating ARDS. Since overweight individuals face a greater risk of pulmonary complications than others, this study aims to assess whether…
Syed-Abdul MM, Tian L, Hegele RA et al. · 2025 · The lancet. Diabetes & endocrinology
There is a well-established link between the severity of hypertriglyceridaemia and acute pancreatitis and long-term triglyceride-lowering therapies known to prevent episodes of acute pancreatitis. Therefore, it has been assumed, without…
Pina L, Eufemio CM, Dove J et al. · 2025 · Surgical endoscopy
Introduction Laparoscopic Sleeve Gastrectomy (LSG) and Laparoscopic Roux-en-Y Gastric Bypass (LRYGB) constitute the most commonly performed bariatric metabolic surgery (BMS) procedures in the USA. The number of robotic-assisted BMS cases…
Pollard J, Parry J, Wilkinson T et al. · 2026 · Case reports in oncology
Introduction Leptomeningeal disease is a rare and devastating complication of ovarian cancer which typically occurs in patients with advanced relapsed disease. It is challenging to treat and associated with a very poor prognosis. Case…
Wierzbicki AS · 2025 · Expert opinion on pharmacotherapy
Introduction Lipid-lowering therapies are well established for the treatment of cardiovascular disease (CVD). Historically monotherapy studies have been performed, but the introduction of statins has led to these drugs being recognized as…
Shimizu K · 2025 · Biological & pharmaceutical bulletin
Multiple sclerosis (MS) develops due to an abnormal T-cell immune response to autoantigens and control of T-cell activation is a mainstream approach for its treatment. In the present study, neogenin, a key molecule for T-cell activation,…
Gonzalez PA, Zamora-Abrahan G, Roa F et al. · 2024 · Preprint
Background: A 32-year-old Filipino female with rheumatoid arthritis and lichen planus of low activity was admitted following a five-week period of painful oral mucosal and cutaneous bullae and erosions over her prior lichen planus lesions…
Sharath S, Sardana K, Khurana A et al. · 2025 · Archives of dermatological research
Background Although there are several reports on use of tofacitinib in lichen planus (LP), its usage in hypertrophic LP is sparse with no data on tissue cytokine expression. Methods We retrospectively analyzed the records of recalcitrant…
Culliton K, Au K, Undurraga S et al. · 2026 · Hand (New York, N.Y.)
Background TDetection of distal radioulnar joint (DRUJ) instability has proven inconsistent despite numerous examination maneuvers. Computed tomography (CT) has been suggested as a modality for evaluating DRUJ instability; however, without…
Karaki Z, Chemaly C, Kotaich J et al. · 2025 · Annals of medicine and surgery (2012)
Introduction and importance Aplastic anemia (AA) is a rare but potentially fatal hematologic disorder in children, marked by bone marrow failure and pancytopenia. Early diagnosis and access to curative treatment such as hematopoietic stem…
Muir R, O’Shea B, Iniesta R et al. · 2024 · Preprint
Objectives Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder, affecting both upper and lower motor neurons. High-density surface electromyography is a non-invasive measure of muscle fasciculations, a phenomenon prevalent…
Mansouri M, Rockne KJ · 2026 · ACS environmental Au
Gas ebullition plays a critical role in facilitating contaminant transport from the sediment to the water column. Predicting gas ebullition accurately is necessary for managing sediments and assessing sediment/water flux, and many…
Nas OF, Kandemirli SG, Korkmaz B et al. · 2025 · Neurological research
Objectives To evaluate success, complications and efficacy for endovascular management for carotid blowout syndrome. Methods Images were evaluated for contrast extravasation, vessel wall irregularity, pseudoaneurysm/aneurysm formation.…
Bruillot M, Pieper A, Sourd D et al. · 2025 · European journal of anaesthesiology
Background Treatment programs designed to enhance recovery after caesarean delivery include multimodal analgesia to ensure optimal analgesia while reducing exposure to systemic opioids. Evidence for the effectiveness of continuous wound…
Domin M, Liew SL, Hordacre B et al. · 2025 · NeuroImage
Indirect structural disconnection-symptom mapping allows white matter impairment to be determined without the need for multi-directional diffusion (MDDW) imaging for each individual. Although widely used this method has not been validated.…
Trost SU, Harindhanavudhi T, Lang Q et al. · 2024 · Preprint
Background: The approval of cystic fibrosis conductance regulator (CFTR) modulators including the triple modulator Elexacaftor/Tezacaftor/Ivacaftor (ETI) for people with cystic fibrosis (pwCF) have improved pulmonary function…
Bhatt HV, Patel D, Rogando D et al. · 2025 · Annals of cardiac anaesthesia
Although thoracic epidural analgesia and paravertebral blocks have well-documented benefits in cardiac surgery, the theoretical risk of neuraxial hematoma in anticoagulated patients limits their use. Fascial plane blocks are recently…
Wattanathorn J, Muchimapura S, Thukham-Mee W et al. · 2025 · Life (Basel, Switzerland)
Owing to the need for a brain supplement targeting neuroprotection against age-related brain disorders and the known effect of carotenoids on brain function, we aimed to assess the effect of consuming carotenoid-rich functional congee for…