A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.
WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.
21290 results · page 319 of 710
Slis A, Parrell B · 2025 · Preprint
Sensory errors, mismatches between predicted sensory outcomes of movement and reafferent sensory feedback, drive changes in the feedforward control of future motor behavior that correct for those errors. Across a wide variety of motor…
Maylott SE, Zeng G, Leung TS et al. · 2025 · Journal of neuroscience research
Sudden infant death syndrome (SIDS)-the sudden and unexplained death of a seemingly healthy infant, < 1 year old-may be associated with abnormalities in the brain regions that underlie breathing and arousal during sleep. While post-mortem…
Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in Veterinary Science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
Evans ND, Fetterman AK · 2026 · Public understanding of science (Bristol, England)
Admitting that one's research findings are wrong involves admitting a potential instance of incompetence, which can keep scientists from engaging in wrongness admission. However, wrongness admission can yield favorable perceptions. In five…
Meier M, Gurri L, Beck K et al. · 2025 · Preprint
Childhood maltreatment (CM) has long-lasting effects on physical and mental health with CM type specific effects being reported. Epigenetic processes, like deoxyribonucleic acid methylation (DNAm), might mediate this link, and CM types…
Frizado AP, O'Reilly MA · 2025 · Physics in medicine and biology
Objective. Although less established than transcranial focused ultrasound (FUS), transvertebral FUS is being developed to treat spinal cord pathologies. Transvertebral sonication of the spinal cord for microbubble-mediated drug delivery…
Appel H, Carmen-Orozco RP, Santiago CP et al. · 2025 · Preprint
The RNA-binding protein Ptbp1 has been proposed as a master regulator of neuronal fate, repressing neurogenesis through its effects on alternative splicing and miRNA maturation. While prior studies using RNA interference suggested that…
Van der Snickt T, Ailliet S, Bassini S et al. · 2025 · Preprint
Enzyme-free isothermal amplification methods offer a promising alternative to enzymatic assays for nucleic acid detection, particularly in low-resource settings. The nonenzymatic isothermal strand displacement and amplification (NISDA)…
Walleczek J, von Stillfried N, Schmidt S et al. · 2025 · Preprint
This metascientific project studied the replicability of Bem Experiment 1, which had claimed a precognitive effect, i.e., the ability to successfully guess the outcome of future random events (Bem. J Pers Soc Psychol. 2011;100: 407-25).…
Li L, Wang Y, Du Z et al. · 2026 · Metabolism: clinical and experimental
Background and aims Targeting key enzymes in hepatic de novo lipogenesis (DNL) presents a promising strategy for treating hypercholesterolemia. However, the precise regulatory mechanisms governing hepatic DNL remain incompletely…
Petersen Dias A, Orsel K, Gammariello CS et al. · 2025 · Research in veterinary science
Digital dermatitis (DD) is a polymicrobial, multifactorial hoof disorder with an undefined etiology, and existing animal models fail to induce a fast, standardized infection in bovine skin. This study explored bacterial inoculation methods…
Willroth EC, Young G, Ford BQ et al. · 2025 · Psychological science
Certain emotion-regulation strategies (e.g., reappraisal) are associated with better well-being and are therefore seen as adaptive (health-promoting) strategies. However, it is unlikely that any strategy is adaptive regardless of context.…
Argenbright CM, Scully IF, Flores D et al. · 2025 · The journal of pain
Pain is a multidimensional phenomenon, encompassing affective-motivational, cognitive-evaluative, and sensory-discriminative domains. Understanding these components is crucial for effective diagnosis and management, particularly in…
Goldberg SB, Baldwin SA, Flynn AWP et al. · 2026 · Clinical psychological science : a journal of the Association for Psychological Science
While it is known that therapists vary in effectiveness, it is unclear what therapist-level characteristics predict this variation. We conducted a large-scale, preregistered study ( n = 97 therapists from the United States and Canada, n =…
Adinugroho I, Bentall R, Stafford T · 2025 · Preprint
This is the first study to attempt replication of Banas et al (2023) on inoculation messages. The original experiment demonstrated that inoculation messages could stimulate resistance to anti-vaccine conspiracy theories. However, a gap was…
Kakeya H, Umeno Y · 2025 · Preprint
Background Kayano et al. estimated the potential number of COVID-19 cases and deaths in Japan from February 17 to November 30, 2021, in a counterfactual scenario where no vaccination was implemented. Their model predicted 63.3 million…
Stawiany K, Kozak K, Sokołowska Z · 2025 · Preprint
The study explores the hypothesis that individuals show greater sympathy towards coherent name-face pairs compared to incoherent pairs, replicating the effect observed by Barton and Halberstadt. A structured questionnaire was designed…
Beldi L, Dong Y, Volet C et al. · 2025 · Preprint
Secondary bile acids, generated through microbial transformation of primary bile acids secreted in bile, play a role in shaping intestinal microbial communities, modulating host immunity, and regulating energy metabolism. In vitro studies…
Dang YL, Esnault K, Leroi MJ et al. · 2025 · Epilepsy & behavior : E&B
Objective Toxoplasma gondii (T. gondii) seropositivity has been reported to have up to a five-fold increased risk for epilepsy. However, substantial heterogeneity in methodology exists across these studies. Furthermore, other studies…
Vaz F, Silva T, Silva E et al. · 2025 · Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine
Pelvic organ prolapse (POP) limits people's quality of life and is quite common in women, especially with advancing age. As cases increase, there is an urgent need for alternative treatments, especially for severe POP, where options remain…
Pachunka A, Jeffries JB, Karr L et al. · 2024 · Preprint
Interacting with animals can improve health and well-being across the lifespan. Some programs such as 4-H and FFA center around youth interacting with animals, potentially enhancing youth development. Mueller (2014) investigated whether…
Mazza A, Voorrips E, Hughes G et al. · 2024 · Preprint
Daily, we perform activities in the presence of others (e.g., office work). While it's well-established that the mere presence of others can influence our performance, it is less clear whether others' performance, rather than just their…
Tavernier N, Wisniewski D, Brass M · 2024 · Preprint
Over the last 15 years, researchers in psychology asserted that manipulating laypeople’s free will beliefs (FWB) has an impact on various downstream social behaviors (such as cheating). More recently, however, many of these findings failed…
Román-Caballero R, Martín-Arévalo E, Martín-Sánchez PDC et al. · 2024 · Consciousness and cognition
Entrainment theories propose that attention inherently oscillates between moments of attentional enhancement and disengagement. Consequently, perceptual and response benefits have been reported in tasks with a rhythmic structure. In the…
Oddleifson C, Kilgus S, Klingbeil DA et al. · 2025 · Journal of school psychology
The purpose of this study was to conduct a conceptual replication of Pendergast et al.'s (2018) study that examined the diagnostic accuracy of a nomogram procedure, also known as a naive Bayesian approach. The specific naive Bayesian…
Tal A, Mudrik L · 2024 · Journal of experimental psychology. General
The field of consciousness studies has yielded various-sometimes contradicting-accounts regarding the function of consciousness, ranging from denying it has such function to claiming that any high-level cognitive function requires…
Romeas T, Goujat M, Faubert J et al. · 2025 · Psychology of sport and exercise
The impact of domain-general cognitive 'brain' training on improving sports performance is highly debated. This study sought to follow-up on research that showcased the benefits of perceptual-cognitive 3D-Multiple Object Tracking (3D-MOT)…
Román-Caballero R, Martín-Arévalo E, Martín-Sánchez PdC et al. · 2024 · Preprint
Entrainment theories propose that attention inherently oscillates between moments of attentional enhancement and disengagement. Consequently, perceptual and response benefits have been reported in tasks with a rhythmic structure. In the…
Houben M, Rief W, Gärtner T et al. · 2024 · Preprint
Abstract Background: Depression is related to a reduced update of negative expectations in response to positive information. Here, we aimed to replicate that cognitive immunization (a cognitive devaluation of expectation-disconfirming…
Whiteford KL, Baltzell LS, Chiu M et al. · 2024 · Preprint
Musical training has been associated with enhanced neural processing of sounds, as measured via the frequency following response (FFR), implying the potential for human subcortical neural plasticity. We conducted a large-scale multi-site…