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Failure-mode index

Search what already failed

A searchable index of real negative results, null findings, and replication failures from the published literature — so you can learn what didn't work before repeating it.

WASTE indexes published research — it does not host or republish full papers. Each entry is a metadata record (title, authors, DOI) compiled from open scholarly databases, with the abstract shown in full only where the paper is openly licensed (e.g. Creative Commons); otherwise a short excerpt is shown for reference under fair use. WASTE classifies each work by failure type; classifications are automated and approximate.

21290 results · page 317 of 710

Negative / Null Result ReportOpen accessMedicine

Viewed touch influences tactile detection by altering decision criterion.

Nair A, Medina J · 2024 · Attention, perception & psychophysics

Our tactile perception is shaped not only by somatosensory input but also by visual information. Prior research on the effect of viewing touch on tactile processing has found higher tactile detection rates when paired with viewed touch…

View details →DOI: 10.3758/s13414-024-02959-7
Failed Experiment ReportMedicine

Within-Subject Manipulations Of Proactive Control Do Not Change Negative Templates Benefits: Exploring the Effect Of Reward On Negative And Positive Cues.

Chidharom M, Tong M, Carlisle NB · 2024 · Visual cognition

Negative templates come from foreknowledge of distractor-features and lead to improved performance during visual search. Recent studies have better characterized the mechanisms underlying these benefits, by showing a critical role of…

View details →DOI: 10.1080/13506285.2024.2315790
Negative / Null Result ReportOpen accessMedicine

Optimal time between decompressive craniectomy and cranioplasty to reduce the risk of complications: A retrospective study.

Stretti F, Parvin R, Fariña Nuñez MT et al. · 2026 · Neurosurgical review

Cranioplasty (CP) is performed after decompressive craniectomy (DC), with complication rates of 15-40%. Risk factors and ideal timing for CP are unclear. This study investigates risk factors for complications after CP and the best time to…

View details →DOI: 10.1007/s10143-025-03993-1
Negative / Null Result ReportMedicine

Interacting with supportive adults predicts greater same-day psychosocial functioning among adolescents in a self-driven learning program.

Ratner K, Zhu G, Li Q et al. · 2023 · Journal of adolescence

Introduction Supportive adults are a critical component of effective out-of-school time (OST) youth programs, yet the short-term dynamics that underlie their role are poorly understood. Within GripTape, a US-wide self-driven learning…

View details →DOI: 10.1002/jad.12149
Failed Experiment ReportOpen accessMedicine

Severe deviation in protein fold prediction by advanced AI: a case study.

López-Sagaseta J, Urdiciain A · 2025 · Scientific reports

Artificial intelligence (AI) and deep learning are making groundbreaking strides in protein structure prediction. AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino…

View details →DOI: 10.1038/s41598-025-89516-w
Negative / Null Result ReportOpen accessMedicine

Novel TTN Mutation Causing Severe Congenital Myopathy and Uncertain Association with Infantile Hydrocephalus.

Balasundaram P, Avulakunta ID, Delfiner L et al. · 2023 · Case reports in genetics

Arthrogryposis multiplex congenita (AMC) is characterized by nonprogressive symmetric contractures of multiple joints with normal intellect and normal systemic examination. AMC is often due to fetal akinesia, which has neurologic,…

View details →DOI: 10.1155/2023/5535083
Negative / Null Result ReportMedicine

Is variability in working memory capacity related to differences in the reactivation of memory traces? A test based on the time-based resource sharing (TBRS) model.

Gonthier C, Gavornikova-Baligand Z · 2023 · Attention, perception & psychophysics

Working memory performance depends on reactivating memory traces, by rapidly switching between refreshing item representations and performing concurrent cognitive processing (time-based resource sharing (TBRS) account). Prior research has…

View details →DOI: 10.3758/s13414-023-02659-8
Negative / Null Result ReportOpen accessMedicine

Does the airway circulation influence airflow obstruction in asthma?

Wanner A · 2025 · BMJ open respiratory research

The airway wall is thickened in asthma and the airway microvasculature participates in the remodelling. It has been assumed but not convincingly demonstrated that the remodelled airway vasculature has a mechanical role in asthma-associated…

View details →DOI: 10.1136/bmjresp-2024-002575
Negative / Null Result ReportMedicine

Salivary amylase gene (AMY1) copy number variation has only a minor correlation with body composition in Chinese adults.

Zhang X, Moran C, Wang R et al. · 2023 · Genes & genomics

Background According to the WHO, about 39% of the global adult population were overweight or obese in 2016. Obesity has high heritability, with more than 1000 variants so far identified. There have been reports indicating that salivary…

View details →DOI: 10.1007/s13258-023-01381-x
Negative / Null Result ReportOpen accessMedicine

Efficacy of cognitive training on cognition, symptoms and functioning: Impact of motivation and attendance.

Fiszdon JM, Wang K, Lê K et al. · 2024 · Schizophrenia research. Cognition

While cognitive remediation therapy (CRT) and compensatory strategy training both have large literature bases supporting their efficacy on both proximal and distal outcomes, the research base on stand-alone cognitive training (CT) is…

View details →DOI: 10.1016/j.scog.2024.100313
Negative / Null Result ReportMedicine

The Association of Oxygen Delivery and Transfusion on Cardiopulmonary Bypass with Acute Kidney Injury.

Engoren M, Janda A, Heung M et al. · 2024 · Journal of cardiothoracic and vascular anesthesia

Objectives To estimate whether the association of transfusion and acute kidney injury (AKI) has a threshold of oxygen delivery below which transfusion is beneficial but above which it is harmful. Design Retrospective study SETTING:…

View details →DOI: 10.1053/j.jvca.2024.04.019
Negative / Null Result ReportOpen accessMedicine

The Impact of GLP-1 Receptor Agonists on Esophagogastroduodenoscopy Outcomes: A Retrospective Cohort Study in a Predominantly African American Population.

El Sabagh A, Abdulraheem A, Jimenez A et al. · 2026 · JGH open : an open access journal of gastroenterology and hepatology

Background Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) improve glycemic control and promote weight loss but may increase gastric residue, raising concerns during esophagogastroduodenoscopy (EGD). African American patients remain…

View details →DOI: 10.1002/jgh3.70370
Negative / Null Result ReportOpen accessMedicine

Impact of a Mindfulness-Based Intervention on Symptoms and Emotion Regulation Strategies in Young Adolescents From the General Population: A Randomized Controlled Trial.

Piguet C, Celen Z, Meuleman B et al. · 2025 · Depression and anxiety

Adolescence is marked by major puberty-induced changes including increased reactivity to stress and a peak incidence of mental disorders. The implementation of early interventions during this developmental period is essential to prevent…

View details →DOI: 10.1155/da/2679049
Negative / Null Result ReportOpen accessMedicine

Dietary inflammatory index and objective disease activity in IBD: no association found.

de Oliveira RMV, Vasques ACJ, Romero SA et al. · 2026 · European journal of clinical nutrition

Background Inflammatory Bowel Disease (IBD) involves genetic and environmental factors, but the relationship between disease activity, adiposity, and diet remains unclear. Objective To investigate the association between…

View details →DOI: 10.1038/s41430-026-01713-6
Negative / Null Result Report

When and why moral exemplars fail to motivate intergroup reconciliation

Péter SZ, Witkowska M-, Szekeres H · 2022 · Preprint

In societies with collective memories of their group’s historical victimization, the modes of conflict resolution conventionally proposed in social psychology may be ineffective. The present study aimed to examine the effectiveness of…

View details →DOI: 10.31234/osf.io/h37ae
Negative / Null Result ReportOpen accessMedicine

Lack of effect of cyclic adenosine monophosphate modulation during prematuration in vitro on development to the blastocyst stage and expression of specific genes associated with lineage commitment.

Desenzi R, Cuellar CJ, Hoorn QA et al. · 2025 · JDS communications

Pharmacological elevation of cyclic AMP (cAMP) of cultured cumulus-oocyte complexes (COC) before or coincident with initiation of maturation has been reported to improve outcomes for various systems for in vitro production of embryos. Here…

View details →DOI: 10.3168/jdsc.2024-0625
Negative / Null Result ReportMedicine

First evidence for the existence of Simkania negevensis in the genitalia of human females.

Abu-Saif RA, Al-Basha AS, Al-Younes HM · 2023 · Enfermedades infecciosas y microbiologia clinica (English ed.)

Introduction Simkania negevensis has been linked to some respiratory and non-respiratory diseases. However, there is still a serious lack of clinical investigations that attempt to determine possible body sites that could be inhabited by…

View details →DOI: 10.1016/j.eimce.2022.11.015
Negative / Null Result ReportOpen accessMedicine

Circulating microRNA-219 in stroke: Lack associations with clinical parameters and post-stroke epilepsy risk.

Fahimi Z, Kazemi M, Rahimi H et al. · 2025 · IBRO neuroscience reports

Background Post-stroke epilepsy (PSE) is a significant complication in stroke survivors, yet early diagnostic biomarkers remain unclear. This study investigated whether circulating microRNA-219 (miR-219) could serve as a reliable biomarker…

View details →DOI: 10.1016/j.ibneur.2025.11.013
Negative / Null Result ReportOpen accessMedicine

Assessing the Impact of PCSK9 and HMGCR Inhibition on Liver Function: Drug-Target Mendelian Randomization Analyses in Four Ancestries.

Rosoff DB, Bell AS, Wagner J et al. · 2024 · Cellular and molecular gastroenterology and hepatology

Background & aims Observational studies have linked lipid-lowering drug targets pro-protein convertase subtilisin/kexin 9 (PCSK9) and HMG-CoA reductase (HMGCR) with adverse liver outcomes; however, liver disease incidence varies across…

View details →DOI: 10.1016/j.jcmgh.2023.09.001